المؤلفون: Grigori Y. Rychkov, Zeeshan Shaukat, Chiao Xin Lim, Rashid Hussain, Ben J. Roberts, Claudia M. Bonardi, Guido Rubboli, Brandon F. Meaney, Robyn Whitney, Rikke S. Møller, Michael G. Ricos, Leanne M. Dibbens

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 15133

مصطلحات موضوعية: epilepsy, K + channels, patch clamping, channelopathies, gain-of-function mutations

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pathology, Diagnostics, and Therapeutics; https://dx.doi.org/10.3390/ijms232315133

الاتاحة: https://doi.org/10.3390/ijms232315133

المؤلفون: Steven A. Weinman, Jie Zhao, Sean C. Kumer, Brian Bridges, Ben J. Roberts, Irina Tikhanovich

مصطلحات موضوعية: 0301 basic medicine, Liver Cirrhosis, Chromatin Immunoprecipitation, Protein-Arginine N-Methyltransferases, Arginine, Transcription, Genetic, Immunology, Active Transport, Cell Nucleus, Histone Deacetylase 1, Biochemistry, Methylation, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, Cell Line, Tumor, Animals, Humans, Myeloid Cells, p300-CBP Transcription Factors, Enzyme Inhibitors, Promoter Regions, Genetic, Molecular Biology, Transcription factor, Cells, Cultured, Mice, Knockout, Innate immune system, Chemistry, Promoter, Cell Biology, M2 Macrophage, Cell biology, 030104 developmental biology, Liver, Acetyltransferase, Protein Processing, Post-Translational, Mannose receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da309942918c324ad04096b60d634317
https://europepmc.org/articles/PMC5555193/

المؤلفون: Ben J Roberts, S Paltoglou

المساهمون: Paltoglou,Steve, Roberts, Benjamin James

المصدر: Oncogene. 26:604-609

مصطلحات موضوعية: Cancer Research, Ubiquitin-Protein Ligases, Molecular Sequence Data, Protein domain, Ubiquitin-conjugating enzyme, Biology, complex mixtures, Ubiquitin, EPAS, VHL, ubiquitin, Skp1, Basic Helix-Loop-Helix Transcription Factors, Genetics, Humans, Amino Acid Sequence, Molecular Biology, Cells, Cultured, chemistry.chemical_classification, DNA ligase, Sequence Homology, Amino Acid, HIF-2, HIF-1, SCF, Hypoxia-Inducible Factor 1, alpha Subunit, Sic1, Protein Structure, Tertiary, Cell biology, Ubiquitin ligase, Biochemistry, chemistry, Von Hippel-Lindau Tumor Suppressor Protein, biology.protein, bacteria, Mutant Proteins, Protein Processing, Post-Translational, Cullin, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::671e38b346d481a2c560fda432b0daaa
https://doi.org/10.1038/sj.onc.1209818

المؤلفون: Ben J Roberts, Martin Lewis

المساهمون: Roberts, Benjamin James, Lewis, Martin David

المصدر: Archives of Biochemistry and Biophysics. 436:237-245

مصطلحات موضوعية: Male, Protein Folding, Time Factors, Cell, endoplasmic retuculum, Endoplasmic Reticulum, Biochemistry, Rats, Sprague-Dawley, Cytosol, Ubiquitin, Carbon Tetrachloride, Endoplasmic Reticulum Chaperone BiP, Heat-Shock Proteins, Cytochrome P-450 CYP2E1, unfolded protein response, Transfection, Oxidants, medicine.anatomical_structure, Liver, Microsomes, Liver, Subcellular Fractions, Proteasome Endopeptidase Complex, DNA, Complementary, BiP, Immunoblotting, Biophysics, CCL4, Biology, digestive system, Cell Line, ubiquitin, medicine, Animals, Humans, CYP2E1, Molecular Biology, Endoplasmic reticulum, HEK 293 cells, Blotting, Northern, Molecular biology, digestive system diseases, Rats, proteasome, Proteasome, biology.protein, Unfolded protein response, RNA, Molecular Chaperones

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7cda7bab04e0c373f8ed7a5e609c9b
https://doi.org/10.1016/j.abb.2005.02.010

المؤلفون: Martin Lewis, Ben J Roberts

المساهمون: Roberts, Benjamin James, Lewis, Martin David

المصدر: Oncogene. 23:2315-2323

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, von Hippel-Lindau Disease, Ubiquitin-Protein Ligases, Clinical Sciences, urologic and male genital diseases, Protein structure, Downregulation and upregulation, Ubiquitin, VHL, Internal medicine, ubiquitin, Genetics, medicine, HIF, cancer, Hypoxia, neoplasms, Molecular Biology, Adaptor Proteins, Signal Transducing, Sequence Deletion, chemistry.chemical_classification, DNA ligase, biology, Tumor Suppressor Proteins, Neuropeptides, Glucose transporter, Signal transducing adaptor protein, female genital diseases and pregnancy complications, Protein Structure, Tertiary, Ubiquitin ligase, Oxygen tension, Cell biology, Endocrinology, chemistry, Von Hippel-Lindau Tumor Suppressor Protein, biology.protein, Carrier Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa3b01642c3517ab0ce5613d84fdea2e
https://doi.org/10.1038/sj.onc.1207384

المؤلفون: Martin Lewis, Ben J Roberts

المساهمون: Roberts, Benjamin James, Lewis, Martin David

المصدر: Oncogene. 22:3992-3997

مصطلحات موضوعية: Cytoplasm, Cancer Research, endocrine system diseases, Integrin alpha5, urologic and male genital diseases, medicine.disease_cause, law.invention, Ligases, Renal cell carcinoma, law, Tumor Cells, Cultured, Glucose Transporter Type 1, RCC, Kidney Neoplasms, Recombinant Proteins, female genital diseases and pregnancy complications, Gene Expression Regulation, Neoplastic, Drug Combinations, Von Hippel-Lindau Tumor Suppressor Protein, Electrophoresis, Polyacrylamide Gel, Proteoglycans, Collagen, Monosaccharide Transport Proteins, Ubiquitin-Protein Ligases, Genetic Vectors, Molecular Sequence Data, Clinical Sciences, Down-Regulation, Biology, Bacterial Proteins, VHL, Genetics, medicine, Humans, HIF, Amino Acid Sequence, Carcinoma, Renal Cell, neoplasms, Molecular Biology, Gene, Cell Nucleus, tumour, Tumor Suppressor Proteins, Cancer, Von hippel lindau, Hypoxia-Inducible Factor 1, alpha Subunit, medicine.disease, Subcellular localization, Molecular biology, Fibronectins, Protein Structure, Tertiary, Luminescent Proteins, nuclear, Microscopy, Fluorescence, Suppressor, Laminin, Carcinogenesis, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b6866dafb811b18114482d104f36d9
https://doi.org/10.1038/sj.onc.1206683

المؤلفون: Ben J. Roberts

المصدر: Journal of Biological Chemistry. 272:9771-9778

مصطلحات موضوعية: Proteasome Endopeptidase Complex, Cytochrome, Leupeptins, Proteolysis, Cysteine Proteinase Inhibitors, Biology, Biochemistry, Mixed Function Oxygenases, Rats, Sprague-Dawley, Cytochrome P-450 Enzyme System, Cytochrome P-450 CYP1A2, Multienzyme Complexes, Cytochrome P-450 CYP3A, medicine, Animals, Molecular Biology, Dose-Response Relationship, Drug, medicine.diagnostic_test, Endoplasmic reticulum, CYP1A2, Cytochrome P450 reductase, Cytochrome P-450 CYP2E1, Oxidoreductases, N-Demethylating, Cell Biology, Acetylcysteine, Rats, Cell biology, Cysteine Endopeptidases, Proteasome, Microsomes, Liver, Microsome, biology.protein, Aryl Hydrocarbon Hydroxylases, Cytochrome P-450 CYP4A

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daa0cebc6029c9c185a3a849b671c7fd
https://doi.org/10.1074/jbc.272.15.9771

المؤلفون: Byoung-Joon Song, Susan E. Shoaf, Ben J. Roberts, Yunjo Soh, Sang S. Park

المصدر: Journal of Biological Chemistry. 270:29632-29635

مصطلحات موضوعية: Ethanol, biology, Chemistry, Cell Biology, Biochemistry, In vitro, Cytosol, chemistry.chemical_compound, Ubiquitin, In vivo, biology.protein, Microsome, Enzyme inducer, Protein stabilization, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e709c35ea276470eef3bd02f464d8147
https://doi.org/10.1074/jbc.270.50.29632

المؤلفون: Ben J Roberts, Steve M Paltoglou

المصدر: Oncogene. 24(23)

مصطلحات موضوعية: Transcriptional Activation, Cancer Research, medicine.medical_specialty, endocrine system diseases, Tumor suppressor gene, Monosaccharide Transport Proteins, Ubiquitin-Protein Ligases, Tumour suppressor protein, chemistry.chemical_element, Cell Count, Biology, urologic and male genital diseases, medicine.disease_cause, Response Elements, Oxygen, Cell Line, Transactivation, Internal medicine, Genetics, medicine, Humans, cardiovascular diseases, Von Hippel–Lindau disease, neoplasms, Molecular Biology, Glucose Transporter Type 1, Tumor Suppressor Proteins, HIF-1alpha, High cell, medicine.disease, Hypoxia-Inducible Factor 1, alpha Subunit, female genital diseases and pregnancy complications, Cell biology, Endocrinology, chemistry, Von Hippel-Lindau Tumor Suppressor Protein, Carcinogenesis, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f4c1e411865a1b7a92ade2a8d9bdf6
https://pubmed.ncbi.nlm.nih.gov/15750626

المؤلفون: Murray L. Whitelaw, Ben J. Roberts

المساهمون: Roberts, Benjamin James, Whitelaw, Murray

المصدر: The Journal of biological chemistry. 274(51)

مصطلحات موضوعية: Proteasome Endopeptidase Complex, Aryl hydrocarbon receptor nuclear translocator, Dioxins, Biochemistry, Cell Line, chemistry.chemical_compound, Multienzyme Complexes, MG132, Animals, Humans, Phosphorylation, Molecular Biology, Transcription factor, Ubiquitins, Nuclear receptor co-repressor 1, Sequence Deletion, biology, Helix-Loop-Helix Motifs, Cell Biology, Hsp90, Cell biology, Cysteine Endopeptidases, Nuclear receptor, chemistry, Proteasome, Receptors, Aryl Hydrocarbon, biology.protein, Signal transduction, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0250a4ae0ec21e7f886b23a322b33ff7
https://pubmed.ncbi.nlm.nih.gov/10593927