المؤلفون: Wainberg, Zev, Melisi, Davide, Macarulla, Teresa, Pazo Cid, Roberto, Chandana, Sreenivasa, De La Fouchardière, Christelle, Dean, Andrew, Kiss, Igor, Lee, Woo, Goetze, Thorsten, Van Cutsem, Eric, Paulson, A, Bekaii-Saab, Tanios, Pant, Shubham, Hubner, Richard, Xiao, Zhimin, Chen, Huanyu, Benzaghou, Fawzi, OReilly, Eileen

المصدر: The Lancet. 402(10409)

مصطلحات موضوعية: Humans, Gemcitabine, Paclitaxel, Pancreatic Neoplasms, Albumins, Adenocarcinoma, Antineoplastic Combined Chemotherapy Protocols

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/54g69911
https://escholarship.org/content/qt54g69911/qt54g69911.pdf

المؤلفون: Okines, Alicia F. C., Curigliano, Giuseppe, Mizuno, Nobumasa, Oh, Do-Youn, Rorive, Andree, Soliman, Hatem, Takahashi, Shunji, Bekaii-Saab, Tanios, Burkard, Mark E., Chung, Ki Y., Debruyne, Philip R., Fox, Jenny R., Gambardella, Valentina, Gil-Martin, Marta, Hamilton, Erika P., Monk, Bradley J., Nakamura, Yoshiaki, Nguyen, Danny, O’Malley, David M., Olawaiye, Alexander B., Pothuri, Bhavana, Reck, Martin, Sudo, Kazuki, Sunakawa, Yu, van Marcke, Cédric, Yu, Evan Y., Ramos, Jorge, Tan, Sherry, Bieda, Mark, Stinchcombe, Thomas E., Pohlmann, Paula R.

المساهمون: UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie, UCL - (SLuc) Unité d'oncologie médicale

المصدر: Nature Medicine, Vol. 1, no.1, p. 1-8 (2025)

Relation: boreal:298176; http://hdl.handle.net/2078.1/298176

الاتاحة: http://hdl.handle.net/2078.1/298176
https://doi.org/10.1038/s41591-024-03462-0

المؤلفون: McNamara, Mairéad, Bridgewater, John, Goyal, Lipika, Jacobs, Timothy, Wagner, Anna, Goldstein, David, Shroff, Rachna, Moehler, Markus, Lowery, Maeve, Bekaii-Saab, Tanios, Kelley, Robin, Furuse, Junji, Rimassa, Lorenza, Morizane, Chigusa, Lamarca, Angela, Hubner, Richard, Knox, Jennifer, Valle, Juan

المصدر: BMJ Open. 12(10)

مصطلحات موضوعية: adult oncology, chemotherapy, hepatobiliary tumours, Humans, Authorship, Biliary Tract Neoplasms, Europe, Physicians, Women, Retrospective Studies, Clinical Trials as Topic, Male, Female

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3020468g
https://escholarship.org/content/qt3020468g/qt3020468g.pdf

المؤلفون: Javle, Milind, Lee, Sunyoung, Azad, Nilofer, Borad, Mitesh, Kate Kelley, Robin, Sivaraman, Smitha, Teschemaker, Anna, Chopra, Ishveen, Janjan, Nora, Parasuraman, Shreekant, Bekaii-Saab, Tanios

المصدر: The Oncologist. 27(10)

مصطلحات موضوعية: SEER program, cholangiocarcinoma, incidence, mortality, prevalence, unknown primary tumor, Adolescent, Adult, Bile Duct Neoplasms, Bile Ducts, Intrahepatic, Cholangiocarcinoma, Dyskinesias, Epilepsy, Benign Neonatal, Humans, Incidence, Neoplasms, Unknown Primary, Retrospective Studies, Seizures, United States, Young Adult

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1zv5t1mx

المؤلفون: Brendel, Karl, Bekaii‐Saab, Tanios, Boland, Patrick M, Dayyani, Farshid, Dean, Andrew, Macarulla, Teresa, Maxwell, Fiona, Mody, Kabir, Pedret‐Dunn, Anna, Wainberg, Zev A, Zhang, Bin

المصدر: CPT Pharmacometrics & Systems Pharmacology. 10(12)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Clinical Research, Rare Diseases, Cancer, Pancreatic Cancer, Clinical Trials and Supportive Activities, Digestive Diseases, Antineoplastic Agents, Carcinoma, Pancreatic Ductal, Diarrhea, Female, Genotype, Glucuronosyltransferase, Humans, Irinotecan, Liposomes, Logistic Models, Male, Metabolic Clearance Rate, Models, Biological, Neoplasm Metastasis, Neutropenia, Pancreatic Neoplasms, Pharmacology and Pharmaceutical Sciences, Medical Physiology, Medical physiology, Pharmacology and pharmaceutical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4f56r0n3

المؤلفون: Kim, Dae Won, Uboha, Nataliya, Alese, Olatunji, Saenger, Yvonne, Zheng, Lei, Fu, Siqing, Gong, Jun, Chaves, Jorge, Chen, Christopher T, Powderly, John D, Zhaohui, Jin, Bekaii-Saab, Tanios, Alistar, Angela T, Gabrail, Nashat, Agensky, Laura, Goel, Apollina, Margossian, Steven, Levisetti, Matteo, Quayle, Steve, Eva Selfridge, J

المصدر: Regular and Young Investigator Award Abstracts ; page A730-A730

الاتاحة: https://doi.org/10.1136/jitc-2024-sitc2024.0636
https://syndication.highwire.org/content/doi/10.1136/jitc-2024-SITC2024.0636

المؤلفون: Strickler, John H, Bekaii-Saab, Tanios, Cercek, Andrea, Heinemann, Volker, Nakamura, Yoshiaki, Raghav, Kanwal, Siena, Salvatore, Tabernero, Josep, Van Cutsem, Eric, Yoshino, Takayuki, Ramos, Jorge, Guan, Xuesong, Andre, Thierry

المساهمون: Seagen Inc

المصدر: Future Oncology ; page 1-9 ; ISSN 1479-6694 1744-8301

الاتاحة: https://doi.org/10.1080/14796694.2024.2441101
https://www.tandfonline.com/doi/pdf/10.1080/14796694.2024.2441101

المؤلفون: Scalia, Isabel G., Sonbol, Mohamad Bassam, Farina, Juan M., Pereyra, Milagros, Wang, Yuxiang, Bekaii-Saab, Tanios S., Yang, Ming, Connolly, Heidi M., Pellikka, Patricia A., Herrmann, Joerg, Halfdanarson, Thorvardur R., Starr, Jason S., Luis, Sushil Allen, Arsanjani, Reza, Ayoub, Chadi

المصدر: JACC: CardioOncology ; ISSN 2666-0873

الاتاحة: https://doi.org/10.1016/j.jaccao.2024.09.008
https://api.elsevier.com/content/article/PII:S2666087324003466?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2666087324003466?httpAccept=text/plain

المؤلفون: Kopetz, Scott, Bekaii-Saab, Tanios, Elez, Elena, Tabernero, Josep, taieb, julien, Yoshino, Takayuki

المساهمون: Institut Català de la Salut, Elez E Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Kopetz S University of Texas MD Anderson Cancer Center, Houston, TX, USA. Tabernero J Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain. Universitat de Vic - Universitat Central de Catalunya, Barcelona, Spain. Bekaii-Saab T Mayo Clinic, Phoenix, AZ, USA. Taieb J Georges Pompidou European Hospital, Université de Paris, Paris, France. Yoshino T National Cancer Center Hospital East, Kashiwa, Japan, Vall d'Hebron Barcelona Hospital Campus

المصدر: Scientia

مصطلحات موضوعية: Anticossos monoclonals - Ús terapèutic, Quimioteràpia combinada, Còlon - Càncer - Tractament, Recte - Càncer - Tractament, Anomalies cromosòmiques, DISEASES::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms, Other subheadings::Other subheadings::Other subheadings::/drug therapy, CHEMICALS AND DRUGS::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Antibodies, Monoclonal, ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Therapeutics::Therapeutics::Drug Therapy::Antineoplastic Protocols::Therapeutics::Drug Therapy::Antineoplastic Combined Chemotherapy Protocols, PHENOMENA AND PROCESSES::Genetic Phenomena::Genetic Variation::Mutation, ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias del sistema digestivo::neoplasias gastrointestinales::neoplasias intestinales::neoplasias colorrectales, Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia, COMPUESTOS QUÍMICOS Y DROGAS::aminoácidos, péptidos y proteínas::proteínas::proteínas sanguíneas::inmunoproteínas::inmunoglobulinas::anticuerpos::anticuerpos monoclonales, TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::terapéutica::farmacoterapia::protocolos antineoplásicos::terapéutica::farmacoterapia::protocolos de quimioterapia antineoplásica combinada, FENÓMENOS Y PROCESOS::fenómenos genéticos::variación genética::mutación

وصف الملف: application/pdf

Relation: Future Oncology;20(11); https://doi.org/10.2217/fon-2022-1249; Elez E, Kopetz S, Tabernero J, Bekaii-Saab T, Taieb J, Yoshino T, et al. SEAMARK: phase II study of first-line encorafenib and cetuximab plus pembrolizumab for MSI-H/dMMR BRAFV600E-mutant mCRC. Futur Oncol. 2024 Apr;20(11):653–63.; https://hdl.handle.net/11351/11294; 001083403100001

الاتاحة: https://hdl.handle.net/11351/11294
https://doi.org/10.2217/fon-2022-1249

المؤلفون: Zheng-Lin, Binbin, Bekaii-Saab, Tanios S.

المصدر: Therapeutic Advances in Medical Oncology ; volume 16 ; ISSN 1758-8359 1758-8359

الاتاحة: http://dx.doi.org/10.1177/17588359231225037
http://journals.sagepub.com/doi/pdf/10.1177/17588359231225037
http://journals.sagepub.com/doi/full-xml/10.1177/17588359231225037

المؤلفون: Mosalem, Osama, Coston, Tucker W, Imperial, Robin, Mauer, Elizabeth, Thompson, Christopher, Yilma, Binyam, Bekaii-Saab, Tanios S, Stoppler, Melissa Conrad, Starr, Jason S

المساهمون: Tempus AI

المصدر: The Oncologist ; ISSN 1083-7159 1549-490X

الاتاحة: http://dx.doi.org/10.1093/oncolo/oyae098
https://academic.oup.com/oncolo/advance-article-pdf/doi/10.1093/oncolo/oyae098/57830007/oyae098.pdf

المؤلفون: Chandana, Sreenivasa R., Woods, Laura M., Maxwell, Fiona, Gandolfo, Ruth, Bekaii-Saab, Tanios

المصدر: European Journal of Cancer ; volume 201, page 113941 ; ISSN 0959-8049

الاتاحة: https://doi.org/10.1016/j.ejca.2024.113941
https://api.elsevier.com/content/article/PII:S0959804924001175?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0959804924001175?httpAccept=text/plain

المؤلفون: Chandana, Sreenivasa R., Woods, Laura M., Maxwell, Fiona, Gandolfo, Ruth, Bekaii-Saab, Tanios

المساهمون: Ipsen Biopharmaceuticals

المصدر: European Journal of Cancer ; volume 198, page 113471 ; ISSN 0959-8049

الاتاحة: http://dx.doi.org/10.1016/j.ejca.2023.113471
https://api.elsevier.com/content/article/PII:S0959804923007736?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0959804923007736?httpAccept=text/plain

المؤلفون: Abidi, Maheen, Aboulafia, David M, Accordino, Melissa K, Acoba, Jared D, Ahluwalia, Manmeet S, Ahmad, Syed A, Ajmera, Archana, Alimohamed, Saif I, Altman, Jessica, Angevine, Anne H, Bakouny, Ziad, Bar, Michael H, Bardia, Aditya, Barnholtz-Sloan, Jill S, Barrow McCollough, Briana, Bashir, Babar, Batist, Gerald, Bekaii-Saab, Tanios S, Berg, Stephanie, Bernicker, Eric H, Bhutani, Divaya, Bilen, Mehmet A, Bindal, Poorva, Bishnoi, Rohit, Blau, Sibel, Bohachek, Pamela, Boland, Genevieve, Bonnen, Mark, Bouchard, Gabrielle, Bouganim, Nathaniel, Bowles, Daniel W, Busser, Fiona J, Butt, Omar, Cabal, Angelo, Cabalona, Wilhelmina D, Cabebe, Elwyn C, Caimi, Paolo, Campian, Jian L, Carducci, Theresa M, Chen, James L, Cheng, Alex, Chism, David D, Choueiri, Toni K, Clark, Melanie J, Clement, Jessica M, Connors, Jean M, Cook, Erin, Curran, Catherine R, Daher, Ahmad, Dailey, Mark E, Davis, Elizabeth J, Dawsey, Scott J, Deeken, John F, Del Prete, Salvatore A, Demetri, George D, Desai, Aakash, Doroshow, Deborah B, Durbin, Eric B, Egan, Pamela C, Elias, Rawad, Elkrief, Arielle, Elms, Destry J, Elshoury, Amro, Faller, Bryan, Farmakiotis, Dimitrios, Fecher, Leslie A, Feldman, Lawrence E, Ferrario, Cristiano, Fiala, Mark A, Flora, Daniel B, French, Benjamin, Friese, Christopher R, Fu, Julie C, Gadgeel, Shirish M, Gainor, Justin, Galsky, Matthew D, Gantt, Gerald, Garcia, Jorge A, Gartrell, Benjamin A, Gatti-Mays, Margaret E, Gill, David M, Gillaspie, Erin A, Giordano, Antonio, Glace, Mary Grace, Glover, Michael J, Goel, Sanjay, Graber, Jerome J, Griffiths, Elizabeth A, Grivas, Petros, Grover, Punita, Gulati, Anthony P, Gulati, Shuchi, Gupta, Shilpa, Gurley, Michael, Hafez, Navid, Halabi, Susan, Halfdanarson, Thorvardur R, Halmos, Balazs, Hausrath, Daniel J, Hawley, Jessica E

المصدر: Cancer Cell. 38(6)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Biological Sciences, Clinical Research, Cancer, COVID-19, COVID-19 Testing, Data Accuracy, Electronic Health Records, Humans, Neoplasms, Quality Improvement, SARS-CoV-2, COVID-19 and Cancer Consortium. Electronic address: jeremy.warner@vumc.org, COVID-19 and Cancer Consortium, Neurosciences, Oncology & Carcinogenesis, Biochemistry and cell biology, Oncology and carcinogenesis

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4r87t16t

المؤلفون: Kuderer, Nicole M, Choueiri, Toni K, Shah, Dimpy P, Shyr, Yu, Rubinstein, Samuel M, Rivera, Donna R, Shete, Sanjay, Hsu, Chih-Yuan, Desai, Aakash, de Lima Lopes, Gilberto, Grivas, Petros, Painter, Corrie A, Peters, Solange, Thompson, Michael A, Bakouny, Ziad, Batist, Gerald, Bekaii-Saab, Tanios, Bilen, Mehmet A, Bouganim, Nathaniel, Larroya, Mateo Bover, Castellano, Daniel, Del Prete, Salvatore A, Doroshow, Deborah B, Egan, Pamela C, Elkrief, Arielle, Farmakiotis, Dimitrios, Flora, Daniel, Galsky, Matthew D, Glover, Michael J, Griffiths, Elizabeth A, Gulati, Anthony P, Gupta, Shilpa, Hafez, Navid, Halfdanarson, Thorvardur R, Hawley, Jessica E, Hsu, Emily, Kasi, Anup, Khaki, Ali R, Lemmon, Christopher A, Lewis, Colleen, Logan, Barbara, Masters, Tyler, McKay, Rana R, Mesa, Ruben A, Morgans, Alicia K, Mulcahy, Mary F, Panagiotou, Orestis A, Peddi, Prakash, Pennell, Nathan A, Reynolds, Kerry, Rosen, Lane R, Rosovsky, Rachel, Salazar, Mary, Schmidt, Andrew, Shah, Sumit A, Shaya, Justin A, Steinharter, John, Stockerl-Goldstein, Keith E, Subbiah, Suki, Vinh, Donald C, Wehbe, Firas H, Weissmann, Lisa B, Wu, Julie Tsu-Yu, Wulff-Burchfield, Elizabeth, Xie, Zhuoer, Yeh, Albert, Yu, Peter P, Zhou, Alice Y, Zubiri, Leyre, Mishra, Sanjay, Lyman, Gary H, Rini, Brian I, Warner, Jeremy L, Consortium, COVID-19 and Cancer, Abidi, Maheen, Acoba, Jared D, Agarwal, Neeraj, Ahmad, Syed, Ajmera, Archana, Altman, Jessica, Angevine, Anne H, Azad, Nilo, Bar, Michael H, Bardia, Aditya, Barnholtz-Sloan, Jill, Barrow, Briana, Bashir, Babar, Belenkaya, Rimma, Berg, Stephanie, Bernicker, Eric H, Bestvina, Christine, Bishnoi, Rohit, Boland, Genevieve, Bonnen, Mark, Bouchard, Gabrielle, Bowles, Daniel W, Busser, Fiona, Cabal, Angelo, Caimi, Paolo, Carducci, Theresa

المصدر: The Lancet. 395(10241)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Health Sciences, Clinical Sciences, Oncology and Carcinogenesis, Infectious Diseases, Prevention, Lung, Coronaviruses, Cancer, Emerging Infectious Diseases, Good Health and Well Being, Aged, Antiviral Agents, Azithromycin, Betacoronavirus, COVID-19, Cause of Death, Comorbidity, Coronavirus Infections, Databases, Factual, Female, Humans, Hydroxychloroquine, Male, Middle Aged, Neoplasms, Pandemics, Pneumonia, Viral, Prognosis, Risk Factors, SARS-CoV-2, COVID-19 Drug Treatment, COVID-19 and Cancer Consortium, Medical and Health Sciences, General & Internal Medicine, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9d33v85q
https://escholarship.org/content/qt9d33v85q/qt9d33v85q.pdf

المؤلفون: Kim, Richard D, McDonough, Shannon, El-Khoueiry, Anthony B, Bekaii-Saab, Tanios S, Stein, Stacey M, Sahai, Vaibhav, Keogh, George P, Kim, Edward J, Baron, Ari D, Siegel, Abby B, Barzi, Afsaneh, Guthrie, Katherine A, Javle, Milind, Hochster, Howard

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Cancer, Digestive Diseases, Clinical Research, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Antineoplastic Combined Chemotherapy Protocols, Biliary Tract Neoplasms, Capecitabine, Female, Fluorouracil, Humans, Male, Middle Aged, Pyridones, Pyrimidinones, Advanced biliary cancer, MEK inhibitor, 5-Fluorouracil, Public Health and Health Services, Oncology & Carcinogenesis, Oncology and carcinogenesis

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/89d2d90n

المؤلفون: Nakamura, Yoshiaki, Mizuno, Nobumasa, Sunakawa, Yu, Canon, Jean-Luc, Galsky, Matthew D, Hamilton, Erika, Hayashi, Hidetoshi, Jerusalem, Guy, Kim, Seung Tae, Lee, Keun-Wook, Kankeu Fonkoua, Lionel Aurelien, Monk, Bradley J, Nguyen, Danny, Oh, Do-Youn, Okines, Alicia, O'Malley, David M, Pohlmann, Paula, Reck, Martin, Shin, Sang Joon, Sudo, Kazuki, Takahashi, Shunji, Van Marcke, Cedric, Yu, Evan Y, Groisberg, Roman, Ramos, Jorge, Tan, Sherry, Stinchcombe, Thomas E, Bekaii-Saab, Tanios

المصدر: Journal of Clinical Oncology, 41 (36), 5569 - 5578 (2023-12-20)

مصطلحات موضوعية: Trastuzumab, ERBB2 protein, human, tucatinib, Antibodies, Monoclonal, Humanized, Receptor, ErbB-2, Humans, Trastuzumab/adverse effects, Receptor, ErbB-2/metabolism, Antineoplastic Combined Chemotherapy Protocols/adverse effects, Antibodies, Monoclonal, Humanized/adverse effects, Neoplasms/drug therapy, Antineoplastic Combined Chemotherapy Protocols, Neoplasms, Oncology, Cancer Research, Human health sciences, Sciences de la santé humaine, Oncologie

Relation: https://ascopubs.org/doi/pdfdirect/10.1200/JCO.23.00606; urn:issn:0732-183X; urn:issn:1527-7755

URL الوصول: https://orbi.uliege.be/handle/2268/313195

المؤلفون: Kaumaya, Pravin TP, Guo, Linlin, Overholser, Jay, Penichet, Manuel L, Bekaii-Saab, Tanios

المصدر: OncoImmunology. 9(1)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Immunology, Vaccine Related, Colo-Rectal Cancer, Biotechnology, Immunotherapy, Digestive Diseases, Prevention, Cancer, Women's Health, Immunization, 5.1 Pharmaceuticals, Good Health and Well Being, Animals, Antibodies, Monoclonal, Humanized, B-Lymphocytes, Cancer Vaccines, Epitopes, B-Lymphocyte, Humans, Mice, Mice, Inbred BALB C, Programmed Cell Death 1 Receptor, Trastuzumab, Immuno-oncology, peptide cancer vaccines, B-cell epitopes, PD-1, PD-L1, nivolumab, CT26/HER-2 model, CT26 carcinoma, HER-2, nivolumab, CT26/HER-2 model, Oncology and carcinogenesis

URL الوصول: https://escholarship.org/uc/item/0ns6q397

المؤلفون: Eva Selfridge, J, Uboha, Nataliya, Saenger, Yvonne, Chaves, Jorge, Zheng, Lei, Powderly, John, Kim, Dae Won, Alese, Olatunji, Fu, Siqing, Gong, Jun, Gabrail, Nashat, Zhaohui, Jin, Bekaii-Saab, Tanios, Alistar, Angela, Agensky, Laura, Goel, Apollina, Margossian, Steven, Quayle, Steve, Levisetti, Matteo

المصدر: Regular and Young Investigator Award Abstracts ; page A846-A846

الاتاحة: http://dx.doi.org/10.1136/jitc-2023-sitc2023.0750
https://syndication.highwire.org/content/doi/10.1136/jitc-2023-SITC2023.0750

المؤلفون: Jamal, Fares, Sahvan, Oudai, Bekaii-Saab, Tanios S., Sonbol, Mohamad Bassam

المصدر: Journal of Clinical Oncology; 2025 Supplement 4, Vol. 43, p820-820, 47p