المؤلفون: Bressan, Elisangela, Reed, Xylena, Bansal, Vikas, Hutchins, Elizabeth, Cobb, Melanie M, Webb, Michelle G, Alsop, Eric, Grenn, Francis P, Illarionova, Anastasia, Savytska, Natalia, Violich, Ivo, Broeer, Stefanie, Fernandes, Noémia, Sivakumar, Ramiyapriya, Beilina, Alexandra, Billingsley, Kimberley J, Berghausen, Joos, Pantazis, Caroline B, Pitz, Vanessa, Patel, Dhairya, Daida, Kensuke, Meechoovet, Bessie, Reiman, Rebecca, Courtright-Lim, Amanda, Logemann, Amber, Antone, Jerry, Barch, Mariya, Kitchen, Robert, Li, Yan, Dalgard, Clifton L, Center, The American Genome, Rizzu, Patrizia, Hernandez, Dena G, Hjelm, Brooke E, Nalls, Mike, Gibbs, J Raphael, Finkbeiner, Steven, Cookson, Mark R, Van Keuren-Jensen, Kendall, Craig, David W, Singleton, Andrew B, Heutink, Peter, Blauwendraat, Cornelis

المصدر: Cell Genomics. 3(3)

مصطلحات موضوعية: Biological Sciences, Genetics, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Stem Cell Research - Induced Pluripotent Stem Cell, Neurosciences, Stem Cell Research, Aging, Parkinson's Disease, Neurodegenerative, Brain Disorders, Human Genome, Aetiology, 2.1 Biological and endogenous factors, Neurological, American Genome Center, Parkinson disease, dopaminergic neurons, genetic risk, induced pluripotent stem cell, omics single-cell RNA sequencing single-cell ATAC sequencing SNCA LRRK2 GBA1

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8nw72976
https://escholarship.org/content/qt8nw72976/qt8nw72976.pdf

المؤلفون: Kluss, Jillian H., Beilina, Alexandra, Williamson, Chad D., Lewis, Patrick A., Cookson, Mark R., Bonet-Ponce, Luis

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2022 Oct . 119(43), 1-12.

URL الوصول: https://www.jstor.org/stable/27208890

المؤلفون: Kluss, Jillian H, Beilina, Alexandra, Williamson, Chad D, Lewis, Patrick A, Cookson, Mark R, Bonet-Ponce, Luis

المصدر: Proceedings of the National Academy of Sciences (PNAS) , 119 (43) , Article e2205492119. (2022)

مصطلحات موضوعية: Science & Technology, Multidisciplinary Sciences, Science & Technology - Other Topics, Parkinson's disease, JIP4, kinase, LLOMe, LYTL, PARKINSONS-DISEASE, PROTEIN RILP, LOCALIZATION, MUTATIONS, TRANSPORT, PATHWAY, FYVE, ARL8, HRS

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10174907/1/Lysosomal%20positioning%20regulates%20Rab10%20phosphorylation%20at%20LRRK2sup%2Bsup%20lysosomes.pdf; https://discovery.ucl.ac.uk/id/eprint/10174907/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10174907/1/Lysosomal%20positioning%20regulates%20Rab10%20phosphorylation%20at%20LRRK2sup%2Bsup%20lysosomes.pdf
https://discovery.ucl.ac.uk/id/eprint/10174907/

المؤلفون: Mamais, Adamantios, Kluss, Jillian H, Bonet-Ponce, Luis, Landeck, Natalie, Langston, Rebekah G, Smith, Nathan, Beilina, Alexandra, Kaganovich, Alice, Ghosh, Manik C, Pellegrini, Laura, Kumaran, Ravindran, Papazoglou, Ioannis, Heaton, George R, Harvey, Kirsten, Bandopadhyay, Rina, Maio, Nunziata, Kim, Changyoun, LaVoie, Matthew J, Gershlick, David C, Cookson, Mark R

المصدر: PLOS Biology , 20 (5) , Article e3001621. (2022)

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10148203/1/Bandopadhyay_Correction%20of%20Mutations%20in%20LRRK2%20linked%20to%20Parkinson%20disease%20sequester%20Rab8a%20to%20damaged%20lysosomes%20and%20regulate%20transferrin-mediated%20iron%20uptake%20in%20microglia_VoR.pdf; https://discovery.ucl.ac.uk/id/eprint/10148203/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10148203/1/Bandopadhyay_Correction%20of%20Mutations%20in%20LRRK2%20linked%20to%20Parkinson%20disease%20sequester%20Rab8a%20to%20damaged%20lysosomes%20and%20regulate%20transferrin-mediated%20iron%20uptake%20in%20microglia_VoR.pdf
https://discovery.ucl.ac.uk/id/eprint/10148203/

المؤلفون: Mamais, Adamantios, Kluss, Jillian H., Bonet-Ponce, Luis, Landeck, Natalie, Langston, Rebekah G., Smith, Nathan, Beilina, Alexandra, Kaganovich, Alice, Ghosh, Manik C., Pellegrini, Laura, Kumaran, Ravindran, Papazoglou, Ioannis, Heaton, George R., Bandopadhyay, Rina, Maio, Nunziata, Kim, Changyoun, LaVoie, Matthew J., Gershlick, David C., Cookson, Mark R.

المساهمون: Südhof, Thomas C., National Institute on Aging

المصدر: PLOS Biology ; volume 19, issue 12, page e3001480 ; ISSN 1545-7885

الاتاحة: http://dx.doi.org/10.1371/journal.pbio.3001480
https://dx.plos.org/10.1371/journal.pbio.3001480

المؤلفون: Mazza, Melissa Conti, Beilina, Alexandra, Roosen, Dorien A., Hauser, David, Cookson, Mark R.

المساهمون: National Institute on Aging, National Heart, Lung, and Blood Institute, National Institutes of Health, National Human Genome Research Institute

المصدر: Stem Cell Research ; volume 55, page 102506 ; ISSN 1873-5061

الاتاحة: http://dx.doi.org/10.1016/j.scr.2021.102506
https://api.elsevier.com/content/article/PII:S1873506121003536?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1873506121003536?httpAccept=text/plain

المؤلفون: Beilina, Alexandra, Van Der Brug, Marcel, Ahmad, Rili, Kesavapany, Sashi, Miller, David W., Petsko, Gregory A., Cookson, Mark R.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2005 Apr . 102(16), 5703-5708.

URL الوصول: https://www.jstor.org/stable/3375371

المؤلفون: Reed, Xylena, Weller, Cory A, Saez-Atienzar, Sara, Beilina, Alexandra, Solaiman, Sultana, Portley, Makayla, Kaileh, Mary, Roy, Roshni, Ding, Jinhui, Zenobia Moore, A, Thad Whitaker, D, Traynor, Bryan J, Raphael Gibbs, J, Scholz, Sonja W, Cookson, Mark R

المصدر: bioRxiv ; ISSN:2692-8205

مصطلحات موضوعية: Epigenetic clock, PBMCs, cell type, iPSCs, methQTL, resource

Relation: https://doi.org/10.1101/2024.12.13.627515; https://pubmed.ncbi.nlm.nih.gov/39713361; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11661179/

الاتاحة: https://doi.org/10.1101/2024.12.13.627515
https://pubmed.ncbi.nlm.nih.gov/39713361
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11661179/

المؤلفون: Heaton, George R., Landeck, Natalie, Mamais, Adamantios, Nalls, Mike A., Nixon-Abell, Jonathon, Kumaran, Ravindran, Beilina, Alexandra, Pellegrini, Laura, Li, Yan, Harvey, Kirsten, Cookson, Mark R.

المساهمون: Intramural Research Program of the National Institute of Health, National Institute on Aging and National Institute on Neurological Disorders and Stroke, Wellcome Trust, Medical Research Council

المصدر: Neurobiology of Disease ; volume 141, page 104948 ; ISSN 0969-9961

الاتاحة: http://dx.doi.org/10.1016/j.nbd.2020.104948
https://api.elsevier.com/content/article/PII:S0969996120302230?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0969996120302230?httpAccept=text/plain

المؤلفون: Beilina, Alexandra, Bonet-Ponce, Luis, Kumaran, Ravindran, Kordich, Jennifer J., Ishida, Morié, Mamais, Adamantios, Kaganovich, Alice, Saez-Atienzar, Sara, Gershlick, David C., Roosen, Dorien A., Pellegrini, Laura, Malkov, Vlad, Fell, Matthew J., Harvey, Kirsten, Bonifacino, Juan S., Moore, Darren J., Cookson, Mark R.

المساهمون: NIH, National Institute on Aging, Eunice Kennedy Shriver National Institute of Child Health and Human Development, University College London

المصدر: Cell Reports ; volume 31, issue 5, page 107614 ; ISSN 2211-1247

الاتاحة: http://dx.doi.org/10.1016/j.celrep.2020.107614
https://api.elsevier.com/content/article/PII:S2211124720305635?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2211124720305635?httpAccept=text/plain

المؤلفون: Bonet-Ponce, Luis, Beilina, Alexandra, Williamson, Chad D., Lindberg, Eric, Kluss, Jillian H., Saez-Atienzar, Sara, Landeck, Natalie, Kumaran, Ravindran, Mamais, Adamantios, Bleck, Christopher K. E., Li, Yan, Cookson, Mark R.

المساهمون: National Institutes of Health

المصدر: Science Advances ; volume 6, issue 46 ; ISSN 2375-2548

الاتاحة: http://dx.doi.org/10.1126/sciadv.abb2454
https://syndication.highwire.org/content/doi/10.1126/sciadv.abb2454
https://www.science.org/doi/pdf/10.1126/sciadv.abb2454

المؤلفون: Wu, Chun-Xiang, Liao, Jingling, Park, Yangshin, Hoang, Neo C., Engel, Victoria A., Wan, Li, Oh, Misook, Sanishvili, Ruslan, Takagi, Yuichiro, Johnson, Steven M., Wang, Mu, Federici, Mark, Nichols, R. Jeremy, Beilina, Alexandra, Reed, Xylena, Cookson, Mark R., Hoang, Quyen Q.

المساهمون: Biochemistry and Molecular Biology, School of Medicine

المصدر: Publisher

مصطلحات موضوعية: LRRK2, Parkinson's disease, GTPase

وصف الملف: application/pdf

Relation: BioRxiv; Wu, C.-X., Liao, J., Park, Y., Hoang, N. C., Engel, V. A., Wan, L., Oh, M., Sanishvili, R., Takagi, Y., Johnson, S. M., Wang, M., Federici, M., Nichols, R. J., Beilina, A., Reed, X., Cookson, M. R., & Hoang, Q. Q. (2019). A revised 1.6 Å structure of the GTPase domain of the Parkinson’s disease-associated protein LRRK2 provides insights into mechanisms. BioRxiv, 676627. https://doi.org/10.1101/676627; https://hdl.handle.net/1805/24934

الاتاحة: https://hdl.handle.net/1805/24934

المؤلفون: Tomkins, James E., Dihanich, Sybille, Beilina, Alexandra, Ferrari, Raffaele, Ilacqua, Nicolò, Cookson, Mark R., Lewis, Patrick A., Manzoni, Claudia

وصف الملف: text

Relation: https://centaur.reading.ac.uk/76656/8/Tomkins_et_al-2017-PROTEOMICS.pdf; https://centaur.reading.ac.uk/76656/1/Tomkins_et_al-2018-PROTEOMICS.pdf; Tomkins, J. E., Dihanich, S., Beilina, A., Ferrari, R., Ilacqua, N., Cookson, M. R., Lewis, P. A. and Manzoni, C. (2018) Comparative protein interaction network analysis identifies shared and distinct functions for the human ROCO proteins. Proteomics, 18 (10). 1700444. ISSN 1615-9853 doi: https://doi.org/10.1002/pmic.201700444

الاتاحة: https://centaur.reading.ac.uk/76656/
https://centaur.reading.ac.uk/76656/8/Tomkins_et_al-2017-PROTEOMICS.pdf
https://centaur.reading.ac.uk/76656/1/Tomkins_et_al-2018-PROTEOMICS.pdf
https://onlinelibrary.wiley.com/doi/abs/10.1002/pmic.201700444

المؤلفون: Pellegrini, Laura, Hauser, David N, Li, Yan, Mamais, Adamantios, Beilina, Alexandra, Kumaran, Ravindran, Wetzel, Andrea, Nixon-Abell, Jonathon, Heaton, George, Rudenko, Iakov, Alkaslasi, Mor, Ivanina, Natalie, Melrose, Heather L, Cookson, Mark R, Harvey, Kirsten

المساهمون: Intramural Research Program of the National Institute of Health, National Institute on Aging and National Institute on Neurological Disorders and Stroke, Medical Research Council

المصدر: Human Molecular Genetics ; volume 27, issue 18, page 3257-3271 ; ISSN 0964-6906 1460-2083

الاتاحة: http://dx.doi.org/10.1093/hmg/ddy232
http://academic.oup.com/hmg/article-pdf/27/18/3257/25643346/ddy232.pdf

المؤلفون: CIVIERO, LAURA, RODELLA, UMBERTO, RUSSO, ISABELLA, BELLUZZI, ELISA, BUBACCO, LUIGI, GREGGIO, ELISA, Cirnaru, Maria Daniela, Beilina, Alexandra, Lobbestael, Evy, Reyniers, Lauran, Hondhamuni, Geshanthi, Lewis, Patrick A, Van den Haute, Chris, Baekelandt, Veerle, Bandopadhyay, Rina, Piccoli, Giovanni, Cookson, Mark R, Taymans, Jean Marc

المساهمون: Civiero, Laura, Cirnaru, Maria Daniela, Beilina, Alexandra, Rodella, Umberto, Russo, Isabella, Belluzzi, Elisa, Lobbestael, Evy, Reyniers, Lauran, Hondhamuni, Geshanthi, Lewis, Patrick A, Van den Haute, Chri, Baekelandt, Veerle, Bandopadhyay, Rina, Bubacco, Luigi, Piccoli, Giovanni, Cookson, Mark R, Taymans, Jean Marc, Greggio, Elisa

مصطلحات موضوعية: LRRK2, Parkinson's disease, neurodegeneration, neuronal cyto-skeleton, p21-activated kinases

وصف الملف: ELETTRONICO

Relation: info:eu-repo/semantics/altIdentifier/pmid/26375402; info:eu-repo/semantics/altIdentifier/wos/WOS:000367192100017; firstpage:n/a; lastpage:n/a; journal:JOURNAL OF NEUROCHEMISTRY; http://hdl.handle.net/11577/3168273; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84955212896

الاتاحة: http://hdl.handle.net/11577/3168273
https://doi.org/10.1111/jnc.13369

المؤلفون: Hauser, David N., Mamais, Adamantios, Conti, Melissa M., Primiani, Christopher T., Kumaran, Ravindran, Dillman, Allissa A., Langston, Rebekah G., Beilina, Alexandra, Garcia, Joseph H., Diaz-Ruiz, Alberto, Bernier, Michel, Fiesel, Fabienne C., Hou, Xu, Springer, Wolfdieter, Li, Yan, de Cabo, Rafael, Cookson, Mark R.

المساهمون: National Institute on Aging, National Institute of Neurological Disorders and Stroke

المصدر: Molecular Neurodegeneration ; volume 12, issue 1 ; ISSN 1750-1326

الاتاحة: http://dx.doi.org/10.1186/s13024-017-0212-x
http://link.springer.com/content/pdf/10.1186/s13024-017-0212-x.pdf
http://link.springer.com/article/10.1186/s13024-017-0212-x/fulltext.html

المؤلفون: Liu, Zhiyong, Bryant, Nicole, Kumaran, Ravindran, Beilina, Alexandra, Abeliovich, Asa, Cookson, Mark R, West, Andrew B

المساهمون: National Institutes of Health, National Institute of Neurological Disorders and Stroke, National Institute on Aging

المصدر: Human Molecular Genetics ; volume 27, issue 2, page 385-395 ; ISSN 0964-6906 1460-2083

الاتاحة: https://doi.org/10.1093/hmg/ddx410
http://academic.oup.com/hmg/article-pdf/27/2/385/24325786/ddx410.pdf

المؤلفون: Mamais, Adamantios, Kluss, Jillian H, Bonet-Ponce, Luis, Landeck, Natalie, Langston, Rebekah G, Smith, Nathan, Beilina, Alexandra, Kaganovich, Alice, Ghosh, Manik C, Pellegrini, Laura, Kumaran, Ravindran, Papazoglou, Ioannis, Heaton, George R, Bandopadhyay, Rina, Maio, Nunziata, Kim, Changyoun, LaVoie, Matthew J, Gershlick, David C, Cookson, Mark R

المصدر: nlmid: 101183755 ; essn: 1545-7885

مصطلحات موضوعية: Aged, Animals, Biological Transport, Corpus Striatum, Gain of Function Mutation, HEK293 Cells, Humans, Iron, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Lysosomes, Male, Mice, Inbred C57BL, Microglia, Middle Aged, Mutation, Parkinson Disease, Protein Serine-Threonine Kinases, Transferrin, Transferrins, rab GTP-Binding Proteins

وصف الملف: application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/333251

الاتاحة: https://doi.org/10.17863/CAM.80674
https://www.repository.cam.ac.uk/handle/1810/333251

المؤلفون: Langston, Rebekah G., Beilina, Alexandra, Reed, Xylena, Kaganovich, Alice, Singleton, Andrew B., Blauwendraat, Cornelis, Gibbs, J. Raphael, Cookson, Mark R.

المصدر: Science Translational Medicine ; volume 14, issue 655 ; ISSN 1946-6234 1946-6242

الاتاحة: http://dx.doi.org/10.1126/scitranslmed.abp8869
https://www.science.org/doi/pdf/10.1126/scitranslmed.abp8869

المؤلفون: van der Brug, Marcel P., Blackinton, Jeff, Chandran, Jayanth, Hao, Ling-Yang, Lal, Ashish, Mazan-Mamczarz, Krystyna, Martindale, Jennifer, Xie, Chengsong, Ahmad, Rili, Thomas, Kelly J., Beilina, Alexandra, Gibbs, J. Raphael, Ding, Jinhui, Myers, Amanda J., Zhan, Ming, Cai, Huaibin, Bonini, Nancy M., Gorospe, Myriam, Cookson, Mark R.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2008 Jul . 105(29), 10244-10249.

URL الوصول: https://www.jstor.org/stable/25463134