المؤلفون: Begnini, Fabio, Geschwindner, Stefan, Johansson, Patrik, Wissler, Lisa, Lewis, Richard J., Danelius, Emma, Luttens, Andreas, Matricon, Pierre, Carlsson, Jens, Lenders, Stijn, König, Beate, Friedel, Anna, Sjö, Peter, Schiesser, Stefan, Kihlberg, Jan

المصدر: Journal of Medicinal Chemistry. 65(4):3473-3517

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-477522
https://doi.org/10.1021/acs.jmedchem.1c01975
https://uu.diva-portal.org/smash/get/diva2:1672725/FULLTEXT01.pdf

المؤلفون: Kurmasheva, Naziia, Said, Aida, Wong, Boaz, Kinderman, Priscilla, Han, Xiaoying, Rahimic, Anna H.F., Kress, Alena, Carter-Timofte, Madalina E., Holm, Emilia, van der Horst, Demi, Kollmann, Christoph F., Liu, Zhenlong, Wang, Chen, Hoang, Huy-Dung, Kovalenko, Elina, Chrysopoulou, Maria, Twayana, Krishna Sundar, Ottosen, Rasmus N, Svenningsen, Esben B., Begnini, Fabio, Kiib, Anders E., Kromm, Florian E.H., Weiss, Hauke J., Di Carlo, Daniele, Muscolini, Michela, Higgins, Maureen, van der Heijden, Mirte, Bardoul, Angelina, Tong, Tong, Ozsvar, Attila, Hou, Wen-Hsien, Schack, Vivien R., Holm, Christian K., Zheng, Yunan, Ruzek, Melanie, Kalucka, Joanna, de la Vega, Laureano, Elgaher, Walid A.M., Korshoej, Anders R., Lin, Rongtuan, Hiscott, John, Poulsen, Thomas B., O'Neill, Luke A., Roy, Dominic G, Rinschen, Markus M., van Montfoort, Nadine, Diallo, Jean-Simon, Farin, Henner F, Alain, Tommy, Olagnier, David

المصدر: Kurmasheva , N , Said , A , Wong , B , Kinderman , P , Han , X , Rahimic , A H F , Kress , A , Carter-Timofte , M E , Holm , E , van der Horst , D , Kollmann , C F , Liu , Z , Wang , C , Hoang , H-D , Kovalenko , E , Chrysopoulou , M , Twayana , K S , Ottosen , R N , Svenningsen , E B , Begnini , F , Kiib , A E , Kromm , F E H ....

مصطلحات موضوعية: Animals, Humans, Oncolytic Virotherapy/methods, Succinates/pharmacology, Mice, Cell Line, Tumor, Oncolytic Viruses, Interferon Type I/metabolism, NF-E2-Related Factor 2/metabolism, Colonic Neoplasms/therapy, Antiviral Agents/pharmacology, NF-kappa B/metabolism, I-kappa B Kinase/metabolism, Kelch-Like ECH-Associated Protein 1/metabolism, Inflammation/drug therapy, Female, Vesicular stomatitis Indiana virus/physiology, Signal Transduction/drug effects, /dk/atira/pure/subjectarea/asjc/1600/1600, name=General Chemistry, /dk/atira/pure/subjectarea/asjc/1300/1300, name=General Biochemistry,Genetics and Molecular Biology, /dk/atira/pure/subjectarea/asjc/3100/3100, name=General Physics and Astronomy

وصف الملف: application/pdf

الاتاحة: https://discovery.dundee.ac.uk/en/publications/031c6e64-cb04-4fa3-813b-15f0b4b2d550
https://doi.org/10.1038/s41467-024-48422-x
https://discovery.dundee.ac.uk/ws/files/124152386/s41467-024-48422-x.pdf
http://www.scopus.com/inward/record.url?scp=85193395304&partnerID=8YFLogxK

المؤلفون: Begnini, Fabio, Poongavanam, Vasanthanathan, Atilaw, Yoseph, Erdélyi, Máté, 1975, Schiesser, Stefan, Kihlberg, Jan

المصدر: ACS Medicinal Chemistry Letters. 12(6):983-990

مصطلحات موضوعية: Cell permeability, conformational sampling, macrocycle, NMR spectroscopy

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-448939
https://doi.org/10.1021/acsmedchemlett.1c00126
https://uu.diva-portal.org/smash/get/diva2:1579970/FULLTEXT01.pdf

المؤلفون: Begnini, Fabio, Poongavanam, Vasanthanathan, Over, Bjorn, Castaldo, Marie, Geschwindner, Stefan, Johansson, Patrik, Tyagi, Mohit, Tyrchan, Christian, Wissler, Lisa, Sjo, Peter, Schiesser, Stefan, Kihlberg, Jan

المصدر: Journal of Medicinal Chemistry. 64(2):1054-1072

مصطلحات موضوعية: PROTEIN-PROTEIN INTERACTION, SMALL MOLECULES, KELCH DOMAIN, PREDICTION, DISCOVERY, INHIBITORS, FRAGMENTS, PROGRAM, BIND, RULE

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-437880
https://doi.org/10.1021/acs.jmedchem.0c01569
https://uu.diva-portal.org/smash/get/diva2:1539004/FULLTEXT01.pdf

المؤلفون: Waqas, Fakhar H., Shehata, Mahmoud, Elgaher, Walid A M, Lacour, Antoine, Kurmasheva, Naziia, Begnini, Fabio, Kiib, Anders E, Dahlmann, Julia, Chen, Chutao, Pavlou, Andreas, Poulsen, Thomas B, Merkert, Sylvia, Martin, Ulrich, Olmer, Ruth, Olagnier, David, Hirsch, Anna K H, Pleschka, Stephan, Pessler, Frank

المصدر: Waqas , F H , Shehata , M , Elgaher , W A M , Lacour , A , Kurmasheva , N , Begnini , F , Kiib , A E , Dahlmann , J , Chen , C , Pavlou , A , Poulsen , T B , Merkert , S , Martin , U , Olmer , R , Olagnier , D , Hirsch , A K H , Pleschka , S & Pessler , F 2023 , ' NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent ....

مصطلحات موضوعية: Humans, Active Transport, Cell Nucleus, Endothelial Cells/metabolism, Influenza A virus/genetics, Influenza A Virus, H1N1 Subtype/genetics, Karyopherins/metabolism, Kelch-Like ECH-Associated Protein 1/metabolism, NF-E2-Related Factor 2/metabolism, Ribonucleoproteins/metabolism, RNA, Messenger/metabolism, Virus Replication

الاتاحة: https://pure.au.dk/portal/en/publications/6d830713-3bee-4c2a-be8e-28c6dcb81c48
https://doi.org/10.1371/journal.ppat.1011506
http://www.scopus.com/inward/record.url?scp=85165687834&partnerID=8YFLogxK

المؤلفون: Begnini, Fabio, Geschwindner, Stefan, Johansson, Patrik, Wissler, Lisa, Lewis, Richard J., Danelius, Emma, Luttens, Andreas, Matricon, Pierre, Carlsson, Jens, Lenders, Stijn, König, Beate, Friedel, Anna, Sjö, Peter, Schiesser, Stefan, Kihlberg, Jan

المساهمون: AstraZeneca, Vetenskapsr?det

المصدر: Journal of Medicinal Chemistry ; volume 66, issue 3, page 2204-2204 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.3c00037
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c00037

المؤلفون: Kurmasheva, Naziia, Said, Aida, Wong, Boaz, Kress, Alena, Liu, Zhenlong, Wang, Chen, Carter-Timofte, Madalina Elena, Holm, Emilia, van der Horst, Demi, Hoang, Huy-Dung, Twayana, Krishna Sundar, Ottosen, Rasmus, Svenningsen, Esben Bjerregaard, Begnini, Fabio, Kiib, Anders Engsted, Weiss, Hauke, Di Carlo, Daniele, Muscolini, Michela, Higgins, Maureen, Kinderman, Priscilla, van der Heijden, Mirte, Tong, Tong, Ozsvar, Attila, Hou, Wen-Hsien, Schack, Vivien, Bach Holm, Christian, van Montfoort, Nadine, Zheng, Yunan, Ruzek, Melanie, Kalucka, Joanna Maria, de la Vega, Laureano, Elgaher, Walid A M, Korshoej, Anders Rosendal, Lin, Rongtuan, Hiscottt, John, Poulsen, Thomas, O´Neill, Luke, Diallo, Jean Simon, Farin, Henner, Alain, Tommy, Olagnier, David Pierre Christophe

المصدر: Kurmasheva , N , Said , A , Wong , B , Kress , A , Liu , Z , Wang , C , Carter-Timofte , M E , Holm , E , van der Horst , D , Hoang , H-D , Twayana , K S , Ottosen , R , Svenningsen , E B , Begnini , F , Kiib , A E , Weiss , H , Di Carlo , D , Muscolini , M , Higgins , M , Kinderman , P , van der Heijden , M , Tong , T , Ozsvar , ....

الاتاحة: https://pure.au.dk/portal/en/publications/f107a053-2154-48e2-ab3b-255bf3875a78
https://doi.org/10.21203/rs.3.rs-3035315/v1

المؤلفون: Begnini, Fabio

المساهمون: Kihlberg, Jan, Professor, Bach, Anders, Associate Professor

المصدر: Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology.

مصطلحات موضوعية: Macrocycles, Keap1-Nrf2, Protein-protein interactions, Natural products

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-454235
https://uu.diva-portal.org/smash/get/diva2:1598713/FULLTEXT01.pdf
https://uu.diva-portal.org/smash/get/diva2:1598713/PREVIEW01.jpg

المؤلفون: Tyagi, Mohit, Begnini, Fabio, Poongavanam, Vasanthanathan, Doak, Bradley C., Kihlberg, Jan

المصدر: Chemistry – A European Journal ; volume 26, issue 1 ; ISSN 0947-6539 1521-3765

الاتاحة: http://dx.doi.org/10.1002/chem.202080163
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchem.202080163
https://onlinelibrary.wiley.com/doi/pdf/10.1002/chem.202080163
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/chem.202080163

المؤلفون: Rainoldi, Giulia, Begnini, Fabio, De Munnik, Mariska, Lo Presti, Leonardo, Vande Velde, Christophe M.L., Orru, Romano, Lesma, Giordano, Ruijter, Eelco, Silvani, Alessandra

المصدر: Rainoldi , G , Begnini , F , De Munnik , M , Lo Presti , L , Vande Velde , C M L , Orru , R , Lesma , G , Ruijter , E & Silvani , A 2018 , ' Sequential Multicomponent Strategy for the Diastereoselective Synthesis of Densely Functionalized Spirooxindole-Fused Thiazolidines ' , ACS Combinatorial Science , vol. 20 , no. 2 , pp. 98-105 . https://doi.org/10.1021/acscombsci.7b00179

مصطلحات موضوعية: Asinger reaction, azido-Ugi reaction, multicomponent reactions, spirooxindole, thiazolidine, Ugi-Joullié reaction

وصف الملف: application/pdf

الاتاحة: https://research.vu.nl/en/publications/044abadd-7ca8-4850-95b7-466d91819aed
https://doi.org/10.1021/acscombsci.7b00179
https://hdl.handle.net/1871.1/044abadd-7ca8-4850-95b7-466d91819aed
https://research.vu.nl/ws/files/72562145/Sequential_Multicomponent_Strategy_for_the_Diastereoselective_Synthesis_of_Densely_Functionalized_Spirooxindole_Fused_Thiazolidines.pdf
http://www.scopus.com/inward/record.url?scp=85041902438&partnerID=8YFLogxK
http://www.scopus.com/inward/citedby.url?scp=85041902438&partnerID=8YFLogxK

المؤلفون: Tyagi, Mohit, Begnini, Fabio, Poongavanam, Vasanthanathan, Doak, Bradley C., Kihlberg, Jan

المصدر: Chemistry - A European Journal. 26(1):49-88

مصطلحات موضوعية: beyond rule of 5, drugs, macrocycles, metathesis, synthesis

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-409042

المؤلفون: Kurmasheva, Naziia, Said, Aida, Wong, Boaz, Kinderman, Priscilla, Han, Xiaoying, Rahimic, Anna H F, Kress, Alena, Carter-Timofte, Madalina E, Holm, Emilia, van der Horst, Demi, Kollmann, Christoph F, Liu, Zhenlong, Wang, Chen, Hoang, Huy-Dung, Kovalenko, Elina, Chrysopoulou, Maria, Twayana, Krishna Sundar, Ottosen, Rasmus N, Svenningsen, Esben B, Begnini, Fabio, Kiib, Anders E, Kromm, Florian E H, Weiss, Hauke J, Di Carlo, Daniele, Muscolini, Michela, Higgins, Maureen, van der Heijden, Mirte, Arulanandam, Rozanne, Bardoul, Angelina, Tong, Tong, Ozsvar, Attila, Hou, Wen-Hsien, Schack, Vivien R, Holm, Christian K, Zheng, Yunan, Ruzek, Melanie, Kalucka, Joanna, de la Vega, Laureano, Elgaher, Walid A M, Korshoej, Anders R, Lin, Rongtuan, Hiscott, John, Poulsen, Thomas B, O'Neill, Luke A, Roy, Dominic G, Rinschen, Markus M, van Montfoort, Nadine, Diallo, Jean-Simon, Farin, Henner F, Alain, Tommy, Olagnier, David

المصدر: Nat Commun ; ISSN:2041-1723 ; Volume:15 ; Issue:1

Relation: https://doi.org/10.1038/s41467-024-55044-w; https://pubmed.ncbi.nlm.nih.gov/39702301; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659427/

الاتاحة: https://doi.org/10.1038/s41467-024-55044-w
https://pubmed.ncbi.nlm.nih.gov/39702301
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659427/

المؤلفون: Begnini, Fabio

مصطلحات الفهرس: Organic Chemistry, Organisk kemi, Licentiate thesis, comprehensive summary, info:eu-repo/semantics/masterThesis, text

URL: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-382646

المؤلفون: Silvani, Alessandra, Rainoldi, Giulia, Begnini, Fabio, Lesma, Giordano

المصدر: Synlett ; volume 27, issue 20, page 2831-2835 ; ISSN 0936-5214 1437-2096

الاتاحة: http://dx.doi.org/10.1055/s-0036-1589286
http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0036-1589286.pdf

المؤلفون: Rainoldi, Giulia, Begnini, Fabio, de Munnik, Mariska, Lo Presti, Leonardo, Vande Velde, Christophe M. L., Orru, Romano, Lesma, Giordano, Ruijter, Eelco, Silvani, Alessandra

المصدر: ACS Combinatorial Science; 20240101, Issue: Preprints

المؤلفون: Rainoldi, Giulia, Begnini, Fabio, Silvani, Alessandra, Lesma, Giordano

المصدر: Synlett; 2016, Vol. 27 Issue 20, p2831-2835, 5p

مصطلحات موضوعية: THIAZOLINES, OXINDOLES, SPIRO compounds synthesis

المؤلفون: Begnini, Fabio, Geschwindner, Stefan, Johansson, Patrik, Wissler, Lisa, Lewis, Richard, Danelius, Emma, Luttens, Andreas, Matricon, Pierre, Carlsson, Jens, Lenders, Stijn, König, Beate, Friedel, Anna, Sjö, Peter, Schiesser, Stefan, Kihlberg, Jan

مصطلحات الفهرس: Biological Sciences, Biologiska vetenskaper, Chemical Sciences, Kemi, Manuscript (preprint), info:eu-repo/semantics/preprint, text

URL: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-454563

المؤلفون: Begnini, Fabio, Geschwindner, Stefan, Johansson, Patrik, Wissler, Lisa, Lewis, Richard, Danelius, Emma, Luttens, Andreas, Matricon, Pierre, Carlsson, Jens, Lenders, Stijn, König, Beate, Friedel, Anna, Sjö, Peter, Schiesser, Stefan, Kihlberg, Jan

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-454563