المؤلفون: Michele De Luca, Donatella Restuccia, Umile Gianfranco Spizzirri, Pasquale Crupi, Giuseppina Ioele, Beatrice Gorelli, Maria Lisa Clodoveo, Simona Saponara, Francesca Aiello

المصدر: Antioxidants, Vol 12, Iss 3, p 622 (2023)

مصطلحات موضوعية: wine lees, green extraction procedure, principal component analysis, partial least square regression, antioxidant properties, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2076-3921/12/3/622; https://doaj.org/toc/2076-3921

URL الوصول: https://doaj.org/article/ff0056aee311471da52fea595a048868

المؤلفون: Gabriele Carullo, Simona Saponara, Amer Ahmed, Beatrice Gorelli, Sarah Mazzotta, Alfonso Trezza, Beatrice Gianibbi, Giuseppe Campiani, Fabio Fusi, Francesca Aiello

المصدر: Marine Drugs, Vol 20, Iss 8, p 515 (2022)

مصطلحات موضوعية: sclareolide, labdane, hypertension, vasorelaxant activity, CaV1.2 channels, KCa1.1 channels, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1660-3397/20/8/515; https://doaj.org/toc/1660-3397

URL الوصول: https://doaj.org/article/6344eb9bf13548c9bf987bc885a2082f

المؤلفون: Federica Pessina, Maria Frosini, Paola Marcolongo, Fabio Fusi, Simona Saponara, Alessandra Gamberucci, Massimo Valoti, Daniela Giustarini, Paolo Fiorenzani, Beatrice Gorelli, Valeria Francardi, Maurizio Botta, Elena Dreassi

المصدر: PLoS ONE, Vol 15, Iss 5, p e0233788 (2020)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/78375ad41d2d45c0a1fc0791bda3cd5a

المؤلفون: Giuseppe Campiani (1714282), Caterina Cavella (7852640), Jeremy D. Osko (5262062), Margherita Brindisi (1714312), Nicola Relitti (5143451), Simone Brogi (715714), A. Prasanth Saraswati (9460123), Stefano Federico (9460126), Giulia Chemi (4887832), Samuele Maramai (1871650), Gabriele Carullo (6384479), Benedikt Jaeger (11113215), Alfonso Carleo (11113218), Rosaria Benedetti (1859671), Federica Sarno (3232011), Stefania Lamponi (140398), Paola Rottoli (8467725), Elena Bargagli (8467728), Carlo Bertucci (1703254), Daniele Tedesco (1703248), Daniel Herp (3930101), Johanna Senger (1463518), Giovina Ruberti (687850), Fulvio Saccoccia (2400835), Simona Saponara (1714297), Beatrice Gorelli (1714279), Massimo Valoti (1960363), Breándan Kennedy (11113221), Husvinee Sundaramurthi (9302249), Stefania Butini (1714288), Manfred Jung (26925), Katy M. Roach (7630040), Lucia Altucci (96038), Peter Bradding (60398), David W. Christianson (1294293), Sandra Gemma (1714309), Antje Prasse (354621)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, HDAC 6, IPF lung tissues, lung model, HDAC 6 overexpression, Biological Evaluation, first-in-class molecules, HDAC activities, vivo toxicity, Structural analysis, fibrotic sphere formation, novel h HDAC 6 inhibitors, binding mode, immunohistochemistry studies, Idiopathic Pulmonary Fibrosis, IPF phenotype, analogue 6 h, Potent Inhibitors Idiopathic, lung disease, h HDAC 1, TGF -β1-dependent fibrogenesis, cell viability

Relation: https://figshare.com/articles/journal_contribution/Harnessing_the_Role_of_HDAC6_in_Idiopathic_Pulmonary_Fibrosis_Design_Synthesis_Structural_Analysis_and_Biological_Evaluation_of_Potent_Inhibitors/14959785

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00184.s001

المؤلفون: Alessandro Papa, Silvia Pasquini, Francesca Galvani, Mariarosaria Cammarota, Chiara Contri, Gabriele Carullo, Sandra Gemma, Anna Ramunno, Stefania Lamponi, Beatrice Gorelli, Simona Saponara, Katia Varani, Marco Mor, Giuseppe Campiani, Francesca Boscia, Fabrizio Vincenzi, Alessio Lodola, Stefania Butini

المساهمون: Papa, Alessandro, Pasquini, Silvia, Galvani, Francesca, Cammarota, Mariarosaria, Contri, Chiara, Carullo, Gabriele, Gemma, Sandra, Ramunno, Anna, Lamponi, Stefania, Gorelli, Beatrice, Saponara, Simona, Varani, Katia, Mor, Marco, Campiani, Giuseppe, Boscia, Francesca, Vincenzi, Fabrizio, Lodola, Alessio, Butini, Stefania

المصدر: European journal of medicinal chemistry. 246

مصطلحات موضوعية: Pharmacology, Endocannabinoid system, Enzyme inhibitors, Fatty acid amide hydrolase, Neuroinflammation, Neuroprotection, Reversible inhibitors, Selective inhibitors, Reversible inhibitor, Organic Chemistry, Enzyme inhibitor, General Medicine, Drug Discovery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505b4efc091e07da1608061ca321b941
https://pubmed.ncbi.nlm.nih.gov/36462439

المؤلفون: Miriam, Durante, Maria, Frosini, Elda, Chiaino, Fabio, Fusi, Alessandra, Gamberucci, Beatrice, Gorelli, Konstantin, Chegaev, Chiara, Riganti, Simona, Saponara

المصدر: Vascular pharmacology. 143

مصطلحات موضوعية: Antibiotics, Antineoplastic, Doxorubicin, Myocytes, Smooth Muscle, Anthracyclines, Muscle, Smooth, Vascular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::de8f03250469d6da7df78256b89b1dff
https://pubmed.ncbi.nlm.nih.gov/35149209

المؤلفون: Alessandro Grillo, Filomena Fezza, Giulia Chemi, Roberto Colangeli, Simone Brogi, Domenico Fazio, Stefano Federico, Alessandro Papa, Nicola Relitti, Roberto Di Maio, Gianluca Giorgi, Stefania Lamponi, Massimo Valoti, Beatrice Gorelli, Simona Saponara, Mascia Benedusi, Alessandra Pecorelli, Patrizia Minetti, Giuseppe Valacchi, Stefania Butini, Giuseppe Campiani, Sandra Gemma, Mauro Maccarrone, Giuseppe Di Giovanni

مصطلحات موضوعية: Endocannabinoid system, enzyme inhibitors, epilepsy, fatty acid amide hydrolase, seizures, selective inhibitors, temporal lobe epilepsy

Relation: https://doi.org/10.1021/acschemneuro.1c00192; https://zenodo.org/communities/fondazionesantaluciairccs; https://doi.org/10.5281/zenodo.6241597; https://doi.org/10.5281/zenodo.6241598; oai:zenodo.org:6241598

الاتاحة: https://doi.org/10.5281/zenodo.6241598

المؤلفون: Gianluca Giorgi, Massimo Valoti, Beatrice Gorelli, Mascia Benedusi, Nicola Relitti, Roberto Colangeli, Sandra Gemma, Mauro Maccarrone, Roberto Di Maio, Stefano Federico, Filomena Fezza, Giuseppe Valacchi, Simone Brogi, Giuseppe Di Giovanni, Alessandro Papa, Stefania Lamponi, Giulia Chemi, Alessandra Pecorelli, Alessandro Grillo, Giuseppe Campiani, Simona Saponara, Patrizia Minetti, Stefania Butini, Domenico Fazio

مصطلحات موضوعية: Endocannabinoid system, Physiology, Cognitive Neuroscience, enzyme inhibitors, Status epilepticus, Hippocampal formation, Pharmacology, Biochemistry, NO, Amidohydrolases, 03 medical and health sciences, chemistry.chemical_compound, Epilepsy, 0302 clinical medicine, Fatty acid amide hydrolase, Seizures, medicine, fatty acid amide hydrolase, Humans, Settore BIO/10, epilepsy, seizures, selective inhibitors, temporal lobe epilepsy, 030304 developmental biology, 0303 health sciences, Chemistry, Dentate gyrus, Cell Biology, General Medicine, Anandamide, medicine.disease, nervous system, Synaptic plasticity, Endocannabinoids, Enzyme Inhibitors, Anticonvulsants, medicine.symptom, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b2bc937d2e3fdb998f3f44e0cfe562
http://hdl.handle.net/11697/172837

المؤلفون: Paola Marcolongo, Federica Pessina, Fabio Fusi, Maria Frosini, Elena Dreassi, Beatrice Gorelli, Valeria Francardi, Massimo Valoti, Paolo Fiorenzani, Daniela Giustarini, Maurizio Botta, Simona Saponara, Alessandra Gamberucci

المصدر: PLoS ONE
PLoS ONE, Vol 15, Iss 5, p e0233788 (2020)

مصطلحات موضوعية: Mealworm, Male, Life Cycles, Captopril, Physiology, Blood Pressure, 030204 cardiovascular system & hematology, medicine.disease_cause, Vascular Medicine, Rats, Inbred WKY, chemistry.chemical_compound, 0302 clinical medicine, Larvae, Heart Rate, Rats, Inbred SHR, Blood plasma, Medicine and Health Sciences, Tenebrio, Mammals, 0303 health sciences, Multidisciplinary, biology, Chemistry, Eukaryota, Heart, Animal Models, Body Fluids, medicine.anatomical_structure, Blood, Experimental Organism Systems, Larva, Hypertension, Vertebrates, Medicine, Anatomy, Animals, Antihypertensive Agents, Dietary Supplements, medicine.drug, Research Article, medicine.medical_specialty, Inbred SHR, Science, Research and Analysis Methods, Rodents, Blood Plasma, 03 medical and health sciences, Model Organisms, Internal medicine, medicine, Inbred WKY, 030304 developmental biology, Nutrition, Organisms, Biology and Life Sciences, Glutathione, Cell Biology, biology.organism_classification, Diet, Rats, Red blood cell, Oxidative Stress, Endocrinology, Blood pressure, Amniotes, Coronary perfusion pressure, Animal Studies, Cardiovascular Anatomy, Oxidative stress, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a1b02cbcd59af371edcdff08d889a5
http://europepmc.org/articles/PMC7259609

المؤلفون: Beatrice Gorelli, Alessandra Vallone, Sarah D'Alessandro, Koen J. Dechering, Karin J.M. Koolen, Stefania Butini, Simone Brogi, Silvia Parapini, Stefania Lamponi, Reto Caldelari, Margherita Brindisi, Gloria Alfano, Fabio Fusi, Sandra Gemma, Giulia Chemi, Joseph M. Jez, Giuseppe Campiani, Donatella Taramelli, Simona Saponara, Soon Goo Lee

المساهمون: Vallone, Alessandra, D'Alessandro, Sarah, Brogi, Simone, Brindisi, Margherita, Chemi, Giulia, Alfano, Gloria, Lamponi, Stefania, Lee, Soon Goo, Jez, Joseph M., Koolen, Karin J. M., Dechering, Koen J., Saponara, Simona, Fusi, Fabio, Gorelli, Beatrice, Taramelli, Donatella, Parapini, Silvia, Caldelari, Reto, Campiani, Giuseppe, Gemma, Sandra, Butini, Stefania

المصدر: European Journal of Medicinal Chemistry. 150:698-718

مصطلحات موضوعية: 0301 basic medicine, Methyltransferase, In silico, Plasmodium falciparum, Gametocyte, Structure-activity relationships, Gametocytes, 01 natural sciences, Article, Antimalarials, Structure-Activity Relationship, 03 medical and health sciences, Parasitic Sensitivity Tests, Piperidines, Drug Discovery, Structure–activity relationship, Malaria Plasmodium falciparum, Antimalarial Agent, Enzyme Inhibitors, Malaria, Falciparum, Furans, Cytotoxicity, Gametocytes, Inhibition, Malaria Plasmodium falciparum, Structure-activity relationships, Inhibition, Pharmacology, chemistry.chemical_classification, Life Cycle Stages, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, Organic Chemistry, Methyltransferases, General Medicine, biology.organism_classification, Malaria, 0104 chemical sciences, 030104 developmental biology, Enzyme, Biochemistry, chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae37839257297231a690a96c423f135
https://doi.org/10.1016/j.ejmech.2018.03.024

المؤلفون: Beatrice Gorelli, Nicola Antonio Colabufo, Simona Saponara, Fabio Fusi, Miriam Durante, Maria Grazia Perrone

المصدر: Journal of Cardiovascular Pharmacology. 70:405-410

مصطلحات موضوعية: Male, medicine.medical_specialty, Tetrahydronaphthalenes, P-glycoprotein, Pharmacology, Cardiovascular System, 030226 pharmacology & pharmacy, Cell Line, 03 medical and health sciences, 0302 clinical medicine, In vivo, medicine.artery, Heart rate, medicine, Animals, Ca(V)1.2 channel current, ATP Binding Cassette Transporter, Subfamily B, Member 1, Rats, Wistar, Aorta, aorta rings, Ca(V)1.2 channel current, Langendorff-perfused heart, PET tracer, P-glycoprotein, Dose-Response Relationship, Drug, Cardiac cycle, medicine.diagnostic_test, Chemistry, PET tracer, Heart, Isolated Heart Preparation, aorta rings, Isoquinolines, Orders of magnitude (mass), Rats, Blood-Brain Barrier, Vasoconstriction, Positron emission tomography, Positron-Emission Tomography, cardiovascular system, Coronary perfusion pressure, Ventricular pressure, Langendorff-perfused heart, Radiology, Radiopharmaceuticals, Cardiology and Cardiovascular Medicine, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d9cbc3d2e898eb38c2b55e532a4ae78
https://doi.org/10.1097/fjc.0000000000000536

المؤلفون: Federica, Pessina, Alessandra, Gamberucci, Jialin, Chen, Boyin, Liu, Peter, Vangheluwe, Beatrice, Gorelli, Stefania, Lorenzini, Ottavia, Spiga, Alfonso, Trezza, Giampietro, Sgaragli, Simona, Saponara

المصدر: Biochemical pharmacology. 155

مصطلحات موضوعية: Male, Dose-Response Relationship, Drug, Butylated Hydroxyanisole, Isolated Heart Preparation, Ryanodine Receptor Calcium Release Channel, Myocardial Contraction, Rats, HEK293 Cells, Heart Rate, Animals, Humans, Calcium, Myocytes, Cardiac, Rats, Wistar

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::aed0ae908507412c1ab810e53ea9ea37
https://pubmed.ncbi.nlm.nih.gov/30036502

المؤلفون: Federica Pessina, Alessandra Gamberucci, Jialin Chen, Boyin Liu, Peter Vangheluwe, Beatrice Gorelli, Stefania Lorenzini, Ottavia Spiga, Alfonso Trezza, Giampietro Sgaragli, Simona Saponara

المساهمون: Pessina, Federica, Gamberucci, Alessandra, Chen, Jialin, Liu, Boyin, Vangheluwe, Peter, Gorelli, Beatrice, Lorenzini, Stefania, Spiga, Ottavia, Trezza, Alfonso, Sgaragli, Giampietro, Saponara, Simona

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/pmid/30036502; info:eu-repo/semantics/altIdentifier/wos/WOS:000445323100041; volume:155; firstpage:434; lastpage:443; numberofpages:10; journal:BIOCHEMICAL PHARMACOLOGY; http://hdl.handle.net/11365/1058383; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85050752188

الاتاحة: http://hdl.handle.net/11365/1058383
https://doi.org/10.1016/j.bcp.2018.07.026

المؤلفون: Alessandra Gamberucci, Beatrice Gorelli, Simona Saponara, Alfonso Trezza, Peter Vangheluwe, Federica Pessina, Stefania Lorenzini, Giampietro Sgaragli, Boyin Liu, Jialin Chen, Ottavia Spiga

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Chronotropic, SERCA, Chemistry, Ryanodine receptor, Diastole, Skeletal muscle, Biochemistry, Ryanodine receptor 2, 03 medical and health sciences, 030104 developmental biology, medicine.anatomical_structure, cardiovascular system, Ventricular pressure, Coronary perfusion pressure, medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f4c7160a5e567ac573e072dce6302a
http://hdl.handle.net/11365/1058383

المؤلفون: Keisuke Ishizawa, Jung Sook Suh, Maria Frosini, Masaki Imanishi, Sarah J. Mitchell, Kai Kappert, Linyong Xu, Georg Dechant, Sui-Lin Mo, Heiko Funke-Kaiser, Piero Tanganelli, Koichiro Tsuchiya, M. Zeitlinger, Ludo Willems, Josef Donnerer, Jae-Wook Oh, Z. Erdogan, A. Burian, Ingrid Liebmann, Ignacio Valencia-Hernández, Bosheng Huang, Christian Humpel, Min-Ji Song, Constanze M. Barwitz, Licht Miyamoto, Giampietro Sgaragli, José Carlos Villegas-Bedolla, Hyung-Sik Kang, Tomoyuki Nishizaki, Alessandra Larini, Shu-Feng Zhou, Jin-Jun Zhang, Geert Meyfroidt, Kisung Ko, Kerstin Seidel, Daniel Godínez-Hernández, Hyun Soo Kwak, Lorenzo Ricci, Luisa Lucas, Victoria C. Cogger, Héctor Urquiza-Marín, Yasumasa Ikeda, Yoshitaka Kihira, Gerald Zernig, Shuhei Tomita, Shoko Fujii, Sarah N. Hilmer, Ming Wei, Haeng-A. Kang, Geert Maleux, Yuling Chen, Rafael de Cabo, Min Park, Beatrice Gorelli, Lai-Bao Sun, Kai K. Kummer, Takeshi Kanno, Xue-Nong Zou, Chris Verslype, Sarah Bernhard, Ki-Mo Lee, Blanca Nateras-Marín, José Antonio Reyes-Ramírez, Sabrina Klare, Toshiaki Tamaki, Akinobu Gotoh, Brett Jones, Janine M. Prast, Hwa-Youn Lee, Eva Schrezenmeier, Christian Böhm, Wan Kyunn Whang, Takumi Sakurada, Shuichi Hamano, Jong Mi Lee, Yuki Izawa-Ishizawa, Isabel Spriet, Aniko Huizer-Pajkos, Chung Hyo Kim, David G. Le Couteur, Massimo Valoti, Sebastian Kirsch, C. Jandrisits, Petra Goldin-Lang, Andrew J. McLachlan, Druck Reinhardt Druck Basel, Uy Dong Sohn, Thao Thanh Nguyen, Sun Young Park, Xian-Guo Liu, Lijun Cao, Neel R. Nabar, Melanie Kroh, Qiu-Lan He, Werner Skuballa, Hisao Nagaya, Frank S. Zollmann, Lixiang Wu, Hironori Taira, Thomas Unger, Kristin Schmerbach

المصدر: Pharmacology. 90:I-IV

مصطلحات موضوعية: Pharmacology, General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2f47e12278c97a01fd01afb1a24b16c0
https://doi.org/10.1159/000345034

المؤلفون: Simona Saponara, Giampietro Sgaragli, Beatrice Gorelli, Fabio Fusi, Cecilia Martelli, Elisabetta Teodori, Virginia Tzankova

المصدر: Pharmacology. 88:137-141

مصطلحات موضوعية: Pharmacology, chemistry.chemical_compound, chemistry, Stereochemistry, Aryl, Cyclohexanol, Amine gas treating, General Medicine, Multidrug-Resistance Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::04235f53b38d86ab67688495fab89a48
https://doi.org/10.1159/000330452

المؤلفون: Lorenzo Di Cesare Mannelli, Livio Luongo, Vincenzo Di Marzo, Margherita Brindisi, Kwang-Mook Jung, Giuseppe Campiani, Anna Pittaluga, Beatrice Gorelli, Fabiana Piscitelli, Carla Ghelardini, Andrea Armirotti, Daniele Tedesco, Christophe Landry, Emanuele Gabellieri, Stefania Lamponi, Stefania Butini, Sandra Gemma, Carlo Bertucci, Alessia Ligresti, Samuele Maramai, Alessandro Grillo, Simone Brogi, Simona Saponara, Marie Pierre Dehouck, Tommaso Bonfiglio, Daniele Piomelli, Sabatino Maione

المساهمون: Brindisi, Margherita, Maramai, Samuele, Gemma, Sandra, Brogi, Simone, Grillo, Alessandro, Di Cesare Mannelli, Lorenzo, Gabellieri, Emanuele, Lamponi, Stefania, Saponara, Simona, Gorelli, Beatrice, Tedesco, Daniele, Bonfiglio, Tommaso, Landry, Christophe, Jung, Kwang Mook, Armirotti, Andrea, Luongo, Livio, Ligresti, Alessia, Piscitelli, Fabiana, Bertucci, Carlo, Dehouck, Marie Pierre, Campiani, Giuseppe, Maione, Sabatino, Ghelardini, Carla, Pittaluga, Anna, Piomelli, Daniele, Di Marzo, Vincenzo, Butini, Stefania, European Research Centre for Drug Discovery and Development, Banchi di Sotto 55 and Dipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena (UNISI), UNIVERSITY OF FIRENZE (UNIVERSITY OF FIRENZE), Università degli Studi di Firenze [Firenze], University of Siena (University of Siena), University of Bologna, University of Genova [Genova, Italy], Laboratoire de la Barrière Hémato-Encéphalique (LBHE), Université d'Artois (UA), University of California, Instituto Italiano di Tecnologia (IIT), Ministero dell'Istruzione-Ministero dell'Economia e Finanze, Second University of Napoli, Endocannabinoid Research Group, Institute of Biomolecular Chemistry (ENDOCANNABINOID RESEARCH GROUP), Consiglio Nazionale delle Ricerche [Roma] (CNR), Institute of Biomolecular Biology, Consiglio Nazionale delle Ricerche (CNR), Department of Pharmacology, Università degli Studi di Siena = University of Siena (UNISI), Università degli Studi di Firenze = University of Florence [Firenze] (UNIFI), Jung, Kwang-Mook, Dehouck, Marie-Pierre, Brindisi, M, Maramai, S, Gemma, S, Brogi, S, Grillo, A, Di Cesare Mannelli, L, Gabellieri, E, Lamponi, S, Saponara, S, Gorelli, B, Tedesco, D, Bonfiglio, T, Landry, C, Jung, Km, Armirotti, A, Ligresti, A, Piscitelli, F, Bertucci, C, Dehouck, Mp, Campiani, G, Ghelardini, C, Pittaluga, A, Piomelli, D, Di Marzo, V, Butini, S.

المصدر: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2016, 59 (6), pp.2612-2632. ⟨10.1021/acs.jmedchem.5b01812⟩
Brindisi, M; Maramai, S; Gemma, S; Brogi, S; Grillo, A; Mannelli, LDC; et al.(2016). Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain. JOURNAL OF MEDICINAL CHEMISTRY, 59(6), 2612-2632. doi: 10.1021/acs.jmedchem.5b01812. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/0nc4z28r
Journal of medicinal chemistry 59 (2016): 2612–2632. doi:10.1021/acs.jmedchem.5b01812
info:cnr-pdr/source/autori:Brindisi M.; Maramai S.; Gemma S.; Brogi S.; Grillo A.; Di Cesare Mannelli L.; Gabellieri E.; Lamponi S.; Saponara S.; Gorelli B.; Tedesco D.; Bonfiglio T.; Landry C.; Jung K.-M.; Armirotti A.; Luongo L.; Ligresti A.; Piscitelli F.; Bertucci C.; Dehouck M.-P.; Campiani G.; Maione S.; Ghelardini C.; Pittaluga A.; Piomelli D.; Di Marzo V.; Butini S./titolo:Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain/doi:10.1021%2Facs.jmedchem.5b01812/rivista:Journal of medicinal chemistry/anno:2016/pagina_da:2612/pagina_a:2632/intervallo_pagine:2612–2632/volume:59

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Proteomics, Cannabinoid receptor, Organoplatinum Compounds, medicine.medical_treatment, [SDV]Life Sciences [q-bio], Pharmacology, Receptor, Cannabinoid, CB2, Mice, Receptor, Cannabinoid, CB1, HEK293 Cell, Models, Drug Discovery, Multiple Sclerosi, Cannabinoid receptor type 2, Encephalomyelitis, Arachidonic Acid, Chemistry, Medicine (all), beta-lactams, Chronic pain, Brain, Animals, Arachidonic Acids, Blood-Brain Barrier, Cell Membrane, Drug Design, Encephalomyelitis, Autoimmune, Experimental, Endocannabinoids, Glycerides, HEK293 Cells, Humans, Monoacylglycerol Lipases, Multiple Sclerosis, Mutagenicity Tests, Neuralgia, Pain, Permeability, Structure-Activity Relationship, Molecular Medicine, Drug Discovery3003 Pharmaceutical Science, CB1, CB2, 3. Good health, Oxaliplatin, lipids (amino acids, peptides, and proteins), MGL inhibitors, medicine.symptom, Human, Receptor, Monoacylglycerol Lipase, Membrane permeability, Neurophysiology, Peptides and proteins, Multiple sclerosis, 03 medical and health sciences, Experimental, medicine, Inverse agonist, Cannabinoid, Endocannabinoid, neuropathic pain, Inhibitors, Animal, Organoplatinum Compound, β-lactams, Molecular, Proteomic, Multiple sclerosis, MGL inhibitors, neuropathic pain, beta-lactams, medicine.disease, Encephalomyeliti, Monoacylglycerol lipase, 030104 developmental biology, Mechanism of action, Mutagenicity Test, Central nervous system, Glyceride, MAGL, Model, Autoimmune

وصف الملف: application/pdf; STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b580f3a9ed3679eb8fef1195b5fa53
http://hdl.handle.net/11588/771110

المؤلفون: Giampietro Sgaragli, Fabio Fusi, Beatrice Gorelli, Federica Pessina, Simona Saponara

المصدر: European Journal of Nutrition. 42:10-17

مصطلحات موضوعية: Aorta, Nutrition and Dietetics, Vascular smooth muscle, Voltage-dependent calcium channel, Chemistry, Medicine (miscellaneous), Rutin, chemistry.chemical_compound, Biochemistry, medicine.artery, medicine, Biophysics, Myocyte, heterocyclic compounds, Patch clamp, Quercetin, Phenylephrine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::697a949b74c1e7d0be235bd47ce70564
https://doi.org/10.1007/s00394-003-0395-5

المؤلفون: BRINDISI, MARGHERITA, BUTINI, STEFANIA, FRANCESCHINI, SILVIA, BROGI, SIMONE, TROTTA, FRANCESCO, Sindu Ros, Alfredo Cagnotto, Mario Salmona, CASAGNI, ALICE, ANDREASSI, MARCO, SAPONARA, SIMONA, Beatrice Gorelli, Pia Weikop, Jens D. Mikkelsen, Jorgen Scheel Kruger, Karin Sandager Nielsen, Ettore Novellino, CAMPIANI, GIUSEPPE, GEMMA, SANDRA

المساهمون: Brindisi, Margherita, Butini, Stefania, Franceschini, Silvia, Brogi, Simone, Trotta, Francesco, Sindu, Ro, Alfredo, Cagnotto, Mario, Salmona, Casagni, Alice, Andreassi, Marco, Saponara, Simona, Gorelli, Beatrice, Pia, Weikop, Mikkelsen, Jens D., Jorgen Scheel Kruger, Karin Sandager Nielsen, Ettore, Novellino, Campiani, Giuseppe, Gemma, Sandra

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/pmid/25343529; info:eu-repo/semantics/altIdentifier/wos/WOS:000345722200026; volume:57; issue:22; firstpage:9578; lastpage:9597; numberofpages:20; journal:JOURNAL OF MEDICINAL CHEMISTRY; https://hdl.handle.net/11365/48230; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84913554344

الاتاحة: https://hdl.handle.net/11365/48230
https://doi.org/10.1021/jm501119j
https://pubs.acs.org/doi/10.1021/jm501119j

المؤلفون: Fabio Fusi, Massimo Valoti, Katia Marazova, Beatrice Gorelli, Gian Pietro Sgaragli

المصدر: European Journal of Pharmacology. 346:237-243

مصطلحات موضوعية: Male, medicine.medical_specialty, Vascular smooth muscle, Contraction (grammar), chemistry.chemical_element, Aorta, Thoracic, Calcium-Transporting ATPases, In Vitro Techniques, Calcium, Endoplasmic Reticulum, Muscle, Smooth, Vascular, Phenylephrine, Nifedipine, Internal medicine, Extracellular, medicine, Animals, Enzyme Inhibitors, Rats, Wistar, Pharmacology, Biological activity, 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester, Hydroquinones, Rats, Calcium Channel Agonists, Endocrinology, chemistry, Mechanism of action, Muscle Tonus, Biophysics, medicine.symptom, Extracellular Space, Adrenergic alpha-Agonists, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc22893d50ea06a8f32d76dd468e84e
https://doi.org/10.1016/s0014-2999(98)00056-9