المؤلفون: Heike Chauvistré, Batool Shannan, Sheena M. Daignault-Mill, Robert J. Ju, Daniel Picard, Stefanie Egetemaier, Renáta Váraljai, Christine S. Gibhardt, Antonio Sechi, Farnusch Kaschani, Oliver Keminer, Samantha J. Stehbens, Qin Liu, Xiangfan Yin, Kirujan Jeyakumar, Felix C. E. Vogel, Clemens Krepler, Vito W. Rebecca, Linda Kubat, Smiths S. Lueong, Jan Forster, Susanne Horn, Marc Remke, Michael Ehrmann, Annette Paschen, Jürgen C. Becker, Iris Helfrich, Daniel Rauh, Markus Kaiser, Sheraz Gul, Meenhard Herlyn, Ivan Bogeski, José Neptuno Rodríguez-López, Nikolas K. Haass, Dirk Schadendorf, Alexander Roesch

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/37bb3c7c6ed14e8aa7ac035cb7135585

المؤلفون: Bradley Garman, Ioannis N. Anastopoulos, Clemens Krepler, Patricia Brafford, Katrin Sproesser, Yuchao Jiang, Bradley Wubbenhorst, Ravi Amaravadi, Joseph Bennett, Marilda Beqiri, David Elder, Keith T. Flaherty, Dennie T. Frederick, Tara C. Gangadhar, Michael Guarino, David Hoon, Giorgos Karakousis, Qin Liu, Nandita Mitra, Nicholas J. Petrelli, Lynn Schuchter, Batool Shannan, Carol L. Shields, Jennifer Wargo, Brandon Wenz, Melissa A. Wilson, Min Xiao, Wei Xu, Xaiowei Xu, Xiangfan Yin, Nancy R. Zhang, Michael A. Davies, Meenhard Herlyn, Katherine L. Nathanson

المصدر: Cell Reports, Vol 21, Iss 7, Pp 1936-1952 (2017)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124717314997; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/050b7f3f632c47dbb71f42de901ed09e

المؤلفون: Clemens Krepler, Katrin Sproesser, Patricia Brafford, Marilda Beqiri, Bradley Garman, Min Xiao, Batool Shannan, Andrea Watters, Michela Perego, Gao Zhang, Adina Vultur, Xiangfan Yin, Qin Liu, Ioannis N. Anastopoulos, Bradley Wubbenhorst, Melissa A. Wilson, Wei Xu, Giorgos Karakousis, Michael Feldman, Xiaowei Xu, Ravi Amaravadi, Tara C. Gangadhar, David E. Elder, Lauren E. Haydu, Jennifer A. Wargo, Michael A. Davies, Yiling Lu, Gordon B. Mills, Dennie T. Frederick, Michal Barzily-Rokni, Keith T. Flaherty, Dave S. Hoon, Michael Guarino, Joseph J. Bennett, Randall W. Ryan, Nicholas J. Petrelli, Carol L. Shields, Mizue Terai, Takami Sato, Andrew E. Aplin, Alexander Roesch, David Darr, Steve Angus, Rakesh Kumar, Ensar Halilovic, Giordano Caponigro, Sebastien Jeay, Jens Wuerthner, Annette Walter, Matthias Ocker, Matthew B. Boxer, Lynn Schuchter, Katherine L. Nathanson, Meenhard Herlyn

المصدر: Cell Reports, Vol 21, Iss 7, Pp 1953-1967 (2017)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124717314535; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/3165039b88f34a199db1a3519c05d121

المؤلفون: Meenhard Herlyn, Ashani T. Weeraratna, Lynn M. Schuchter, Malte Peters, Markus Boehm, Giordano Caponigro, Poulikos I. Poulikakos, Tamer A. Ahmed, Yiling Lu, Gordon B. Mills, Giorgos C. Karakousis, Xiaowei Xu, Katherine L. Nathanson, Bradley Garman, Wei Xu, Qin Liu, Marilda Beqiri, Batool Shannan, Patricia A. Brafford, Katrin Sproesser, Min Xiao, Clemens Krepler

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08bb2c8ffab75aabe628e9c20b338739
https://doi.org/10.1158/1078-0432.c.6524043.v1

المؤلفون: Meenhard Herlyn, Ashani T. Weeraratna, Lynn M. Schuchter, Malte Peters, Markus Boehm, Giordano Caponigro, Poulikos I. Poulikakos, Tamer A. Ahmed, Yiling Lu, Gordon B. Mills, Giorgos C. Karakousis, Xiaowei Xu, Katherine L. Nathanson, Bradley Garman, Wei Xu, Qin Liu, Marilda Beqiri, Batool Shannan, Patricia A. Brafford, Katrin Sproesser, Min Xiao, Clemens Krepler

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a6ff506c298bc0e58a02977c288bce
https://doi.org/10.1158/1078-0432.22458783.v1

المؤلفون: Meenhard Herlyn, Ashani T. Weeraratna, Lynn M. Schuchter, Malte Peters, Markus Boehm, Giordano Caponigro, Poulikos I. Poulikakos, Tamer A. Ahmed, Yiling Lu, Gordon B. Mills, Giorgos C. Karakousis, Xiaowei Xu, Katherine L. Nathanson, Bradley Garman, Wei Xu, Qin Liu, Marilda Beqiri, Batool Shannan, Patricia A. Brafford, Katrin Sproesser, Min Xiao, Clemens Krepler

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36db26dddeff86d69ec7031316ca4dcc
https://doi.org/10.1158/1078-0432.22458780

المؤلفون: Ioana Stejerean‐Todoran, Katharina Zimmermann, Christine S Gibhardt, Adina Vultur, Christian Ickes, Batool Shannan, Zuriñe Bonilla del Rio, Anna Wölling, Sabrina Cappello, Hsu‐Min Sung, Magdalena Shumanska, Xin Zhang, Maithily Nanadikar, Muhammad U Latif, Anna Wittek, Felix Lange, Andrea Waters, Patricia Brafford, Jörg Wilting, Henning Urlaub, Dörthe M Katschinski, Peter Rehling, Christof Lenz, Stefan Jakobs, Volker Ellenrieder, Alexander Roesch, Michael P Schön, Meenhard Herlyn, Hedwig Stanisz, Ivan Bogeski

المصدر: EMBO Reports

مصطلحات موضوعية: Proteomics, Phenotype, Cell Line, Tumor, Genetics, Medizin, Humans, Calcium, Molecular Biology, Biochemistry, Melanoma, Oxidation-Reduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada40a69551e61b8ea0ca78c0f785408
https://pubmed.ncbi.nlm.nih.gov/36156348

المؤلفون: Frank Meiss, Heike Chauvistré, Dirk Schadendorf, Thomas G. P. Grunewald, Giuseppina Sannino, Evelyn Dabrowski, J. Utikal, Susanne Horn, Lisa Zimmer, Renáta Váraljai, Andrea Forschner, Diana Klein, Björn Scheffler, Friedegund Meier, Verena Jendrossek, Johann Matschke, Lucie Heinzerling, Martin Stuschke, Felix C. E. Vogel, Joachim Klode, Elisabeth Livingstone, D Westphal, A. Hoewner, Alexander Roesch, Patrick Terheyden, J Bruns, Batool Shannan, Carola Berking, Ralf Gutzmer, David Rafei-Shamsabadi, Ricarda Rauschenberg, Aruna Marchetto

المصدر: European Journal of Cancer. 109:137-153

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Cancer Research, Cell growth, business.industry, Melanoma, medicine.medical_treatment, Cell cycle, medicine.disease, Targeted therapy, Radiation therapy, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, medicine, Cancer research, Neoplasm, business, Chemoradiotherapy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1fb0c9565ed17aa186f27a71eeef729a
https://doi.org/10.1016/j.ejca.2018.12.024

المؤلفون: Marc Remke, Stefanie Egetemaier, Nikolas K. Haass, Smiths S Lueong, Markus Kaiser, Heike Chauvistré, José Neptuno Rodríguez-López, Linda Kubat, Clemens Krepler, Antonio Sechi, Batool Shannan, Qin Liu, Robert J. Ju, Farnusch Kaschani, Alexander Roesch, Sheraz Gul, Jürgen C. Becker, Vito W. Rebecca, Jan Forster, Iris Helfrich, Susanne Horn, Annette Paschen, Daniel Rauh, S. M. Daignault, Kirujan Jeyakumar, Meenhard Herlyn, Xiangfan Yin, Dirk Schadendorf, Daniel Picard, Felix C. E. Vogel, Michael Ehrmann, Renáta Váraljai, Oliver Keminer, Samantha J. Stehbens

المساهمون: Publica

مصطلحات موضوعية: Cell, Medizin, General Physics and Astronomy, Context (language use), General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, medicine, Humans, Melanoma, Gene, Cell Proliferation, 030304 developmental biology, Phenocopy, 0303 health sciences, Multidisciplinary, biology, Monophenol Monooxygenase, Cell growth, General Chemistry, medicine.disease, medicine.anatomical_structure, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Melanocytes, Demethylase, JARID1B

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b04ae9486f97f99a6fdc8d596aa08fa
https://doi.org/10.1101/2020.04.01.999847

المؤلفون: Heike Chauvistré, Alexander Roesch, Kilian Wistuba-Hamprecht, Benjamin Weide, Jürgen C. Becker, Andreas Stang, Batool Shannan, Felix C. E. Vogel, Susanne Horn, Peter A. Horn, Teofila Seremet, Renáta Váraljai, Jérémie Nsengimana, Nils von Neuhoff, Joey Mark S. Diaz, Bart Neyns, Julia Newton-Bishop, Dirk Schadendorf, Klaus G. Griewank, Antje Sucker

المساهمون: Clinical sciences, Medical Oncology, Laboratory for Medical and Molecular Oncology, Laboratory of Molecullar and Cellular Therapy

المصدر: Journal of Clinical Oncology

مصطلحات موضوعية: Cancer Research, Metastatic melanoma, business.industry, Medizin, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, Cancer research, Medicine, Liquid biopsy, Monitoring tool, business, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eefe13f65a05ee1a64f811328e968ca
https://doi.org/10.1200/jco.2019.37.15_suppl.9548

المؤلفون: Andrea Watters, Xiangfan Yin, Stefan Mollin, Clemens Krepler, Phyllis A. Gimotty, Adina Vultur, Joseph L. Benci, Gao Zhang, Quan Chen, Katherine L. Nathanson, Patricia Brafford, Ling Li, Xiaowei Xu, Markus Dörr, Qin Liu, Batool Shannan, Jie Zhang, Eric Meggers, Zhi Wei, Meenhard Herlyn, Michela Perego

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Gerontology, Indoles, Medizin, Mice, SCID, medicine.disease_cause, 0302 clinical medicine, Mice, Inbred NOD, hemic and lymphatic diseases, SGI-1776, Antineoplastic Combined Chemotherapy Protocols, ortho-Aminobenzoates, Mice, Knockout, Sulfonamides, Kinase, Melanoma, Imidazoles, University hospital, 3. Good health, Tumor Burden, Pyridazines, Oncology, Pim kinases, 030220 oncology & carcinogenesis, RNA Interference, Heterocyclic Compounds, 3-Ring, Research Paper, organometallics, Pyrimidinones, Protein Serine-Threonine Kinases, 03 medical and health sciences, Proto-Oncogene Proteins c-pim-1, Cell Line, Tumor, Proto-Oncogene Proteins, medicine, melanoma, Animals, Humans, neoplasms, PI3K/AKT/mTOR pathway, Advanced melanoma, Cell Proliferation, therapy, business.industry, Gene Expression Profiling, PIM kinases, Cancer, medicine.disease, Xenograft Model Antitumor Assays, 030104 developmental biology, Cancer research, business, Carcinogenesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00f0b3f281bd656655ec1861c8f1bd6
http://europepmc.org/articles/PMC5342389

المؤلفون: Shijie Zha, Young Chan Chae, Elaida Dimwamwa, Keith T. Flaherty, Lynn M. Schuchter, Dario C. Altieri, Narayan G. Avadhani, Gao Zhang, Wei Xu, Patricia Brafford, Mengnan Gu, Qin Liu, Batool Shannan, Jephrey Y. Liu, Ashani T. Weeraratna, Manti Guha, Min Xiao, Giorgos C. Karakousis, Satish Srinivasan, Jie Zhang, Devraj Basu, Xiaowei Xu, Dennie T. Frederick, Zhi Wei, Clemens Krepler, Katrin Sproesser, Gordon B. Mills, Tara C. Gangadhar, Harry Choi, Michael A. Davies, Tian Tian, Ravi K. Amaravadi, Abheek Ghosh, Omotayo Ope, Caiyue Xu, Meenhard Herlyn, Yiling Lu, Lawrence Wu, Dongmei Zhang, Weiting Xu, Jennifer A. Wargo, Sergio Randell

المصدر: Journal of Clinical Investigation. 126:1834-1856

مصطلحات موضوعية: Male, 0301 basic medicine, MAPK/ERK pathway, Mitochondrial DNA, Lactams, Macrocyclic, Biology, Mitochondrion, Guanidines, Mitochondrial Dynamics, Article, Hsp90 inhibitor, Mitochondrial Proteins, Mice, 03 medical and health sciences, Animals, Humans, Integrated stress response, HSP90 Heat-Shock Proteins, Extracellular Signal-Regulated MAP Kinases, Melanoma, Protein Kinase Inhibitors, Transcription factor, General Medicine, TFAM, Mitochondria, Neoplasm Proteins, Cell biology, DNA-Binding Proteins, 030104 developmental biology, Mitochondrial biogenesis, Female, Transcription Factors, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74e94cfd6e0f67de1b11babaf588419
https://doi.org/10.1172/jci82661

المؤلفون: Yiling Lu, Giordano Caponigro, Katherine L. Nathanson, Marilda Beqiri, Qin Liu, Lynn M. Schuchter, Poulikos I. Poulikakos, Ashani T. Weeraratna, Min Xiao, Giorgos C. Karakousis, Clemens Krepler, Wei Xu, Katrin Sproesser, Gordon B. Mills, Meenhard Herlyn, Batool Shannan, Xiaowei Xu, Bradley Garman, Patricia Brafford, Tamer A. Ahmed, Markus Boehm, Malte Peters

المصدر: Clinical Cancer Research. 22:1592-1602

مصطلحات موضوعية: 0301 basic medicine, Neuroblastoma RAS viral oncogene homolog, Cancer Research, Combination therapy, biology, business.industry, Melanoma, Cancer, Binimetinib, medicine.disease, Bioinformatics, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Oncology, chemistry, 030220 oncology & carcinogenesis, Encorafenib, medicine, Cancer research, biology.protein, PTEN, Personalized medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2c4157996be02b7142f8a0e99c0f18eb
https://doi.org/10.1158/1078-0432.ccr-15-1762

المؤلفون: Quan Chen, Clemens Krepler, Andrea Watters, Scott Peterson, Batool Shannan, Geena Rajan, Ashani T. Weeraratna, Tara C. Gangadhar, Phyllis A. Gimotty, Melissa Wilson, Michela Perego, Lynn M. Schuchter, Adina Vultur, Katherine L. Nathanson, Meenhard Herlyn, Ling Li, Rakhee Thombre

المصدر: Pigment Cell & Melanoma Research. 29:317-328

مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, 0301 basic medicine, Indoles, Medizin, 3d model, Gonanes, Dermatology, Models, Biological, Article, General Biochemistry, Genetics and Molecular Biology, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, Mediator, Mice, Inbred NOD, In vivo, Cell Line, Tumor, Spheroids, Cellular, Cell Adhesion, Tumor Microenvironment, medicine, Animals, Melanoma, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Cell Proliferation, Phosphoinositide-3 Kinase Inhibitors, Sulfonamides, Tumor microenvironment, business.industry, Cell growth, medicine.disease, 030104 developmental biology, Oncology, Mutation, Cancer research, Collagen, Signal transduction, business, Proto-Oncogene Proteins c-akt, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fce6225ed44ca36077990c33aa2f4da
https://doi.org/10.1111/pcmr.12465

المؤلفون: David E. Elder, Michael A. Davies, Yuchao Jiang, Katherine L. Nathanson, Keith T. Flaherty, Marilda Beqiri, Qin Liu, Nicholas J. Petrelli, Tara C. Gangadhar, Xiangfan Yin, Michael J. Guarino, Carol L. Shields, Dennie T. Frederick, Nandita Mitra, Nan Zhang, Jennifer A. Wargo, Min Xiao, Giorgos C. Karakousis, Batool Shannan, Bradley Garman, Dave S.B. Hoon, Clemens Krepler, Lynn M. Schuchter, Meenhard Herlyn, Xaiowei Xu, Katrin Sproesser, Bradley Wubbenhorst, Wei Xu, Patricia Brafford, Brandon Wenz, Ioannis N. Anastopoulos, Joseph J. Bennett, Ravi K. Amaravadi, Melissa Wilson

المصدر: Cell Reports, Vol 21, Iss 7, Pp 1936-1952 (2017)

مصطلحات موضوعية: 0301 basic medicine, Neuroblastoma RAS viral oncogene homolog, Adult, Male, MAP Kinase Signaling System, medicine.medical_treatment, Gene mutation, Biology, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Article, Targeted therapy, 03 medical and health sciences, Mice, Cell Line, Tumor, medicine, Animals, Humans, Gene, lcsh:QH301-705.5, neoplasms, Melanoma, Aged, Repetitive Sequences, Nucleic Acid, Genetics, Aged, 80 and over, Mutation, Massive parallel sequencing, Genome, Immunotherapy, Oncogenes, Middle Aged, medicine.disease, 3. Good health, 030104 developmental biology, lcsh:Biology (General), Cancer research, Heterografts, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9daa55337f7b89545a481ebc7d52b5dc
https://pubmed.ncbi.nlm.nih.gov/29141224

المؤلفون: Anna Lena Merkel, Lena Kastl, Adina Vultur, Kathrin Wähler, Batool Shannan, Matthias Ocker, Wolfgang J. Parak, Klaus Harms, Sandra Dieckmann, Timo Völker, Anja Kastl, Meenhard Herlyn, Eric Meggers

المصدر: ChemMedChem. 8:924-927

مصطلحات موضوعية: Models, Molecular, Light, Stereochemistry, Chemical biology, chemistry.chemical_element, Antineoplastic Agents, Crystallography, X-Ray, Biochemistry, Article, Structure-Activity Relationship, Drug Discovery, Organometallic Compounds, Humans, General Pharmacology, Toxicology and Pharmaceutics, Cell Proliferation, Pharmacology, Dose-Response Relationship, Drug, Molecular Structure, Drug discovery, Ligand, Organic Chemistry, Exchange kinetics, Rhenium, chemistry, Molecular Medicine, Drug Screening Assays, Antitumor, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f112e4f6560d8027b66e669c3f1cd511
https://doi.org/10.1002/cmdc.201300060

المؤلفون: Diana Klein, Friedegund Meier, Felix C. E. Vogel, J. Verena, Johann Matschke, Alexander Roesch, Batool Shannan, Dirk Schadendorf, Heike Chauvistré

المصدر: ESMO Open. 3:A358

مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, biology, business.industry, DNA repair, medicine.medical_treatment, Melanoma, Cell cycle, medicine.disease, Radiation therapy, Oncology, Cell culture, In vivo, medicine, Cancer research, biology.protein, JARID1B, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f25107399677a9cc7b9cdb86d8324d04
https://doi.org/10.1136/esmoopen-2018-eacr25.844

المؤلفون: Dirk Schadendorf, Felix C. E. Vogel, Alexander Roesch, Heike Chauvistré, Batool Shannan, Elmar Zügner, Christoph Magnes, N. Bordag

المصدر: ESMO Open. 3:A123

مصطلحات موضوعية: Cancer Research, biology, Cell growth, medicine.medical_treatment, Melanoma, Cell, medicine.disease, Warburg effect, Targeted therapy, medicine.anatomical_structure, Oncology, medicine, Cancer research, biology.protein, Demethylase, Epigenetics, JARID1B

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e711fc95b14245a5231d2ab9349f12f6
https://doi.org/10.1136/esmoopen-2018-eacr25.295

المؤلفون: Batool, Shannan, Michela, Perego, Rajasekharan, Somasundaram, Meenhard, Herlyn

المصدر: Cancer treatment and research. 167

مصطلحات موضوعية: Biomarkers, Tumor, Humans, Melanoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::d0d12ec1dc9faa77696efa04f4c4cf1c
https://pubmed.ncbi.nlm.nih.gov/26601857

المؤلفون: Michela Perego, Rajasekharan Somasundaram, Batool Shannan, Meenhard Herlyn

المصدر: Melanoma ISBN: 9783319225388

مصطلحات موضوعية: 0301 basic medicine, Therapy Outcome, Oncology, medicine.medical_specialty, business.industry, Melanoma, medicine.disease, Tumor heterogeneity, Clinical trial, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Therapy response, 030220 oncology & carcinogenesis, Research community, Internal medicine, medicine, Biomarker (medicine), business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e28a9216ab58bc613aeae76cf5aa04d8
https://doi.org/10.1007/978-3-319-22539-5_1