المؤلفون: Karalis, Vasiliki, Caval-Holme, Franklin, Bateup, Helen S

المصدر: Nature Communications. 13(1)

مصطلحات موضوعية: Biological Sciences, Biomedical and Clinical Sciences, Genetics, Brain Disorders, Tuberous Sclerosis, Neurosciences, Rare Diseases, Intellectual and Developmental Disabilities (IDD), Neurological, Animals, Disease Models, Animal, Down-Regulation, Mechanistic Target of Rapamycin Complex 1, Mechanistic Target of Rapamycin Complex 2, Mice, Neurons, Regulatory-Associated Protein of mTOR, Sirolimus, TOR Serine-Threonine Kinases

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/46h5413x
https://escholarship.org/content/qt46h5413x/qt46h5413x.pdf

المؤلفون: Deb, Bipan K, Bateup, Helen S

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Biomedical and Clinical Sciences, Biological Psychology, Psychology, Human Genome, Mental Health, Brain Disorders, Neurosciences, Neurodegenerative, Stem Cell Research, Stem Cell Research - Embryonic - Human, Pediatric, Stem Cell Research - Nonembryonic - Non-Human, Genetics, Stem Cell Research - Nonembryonic - Human, Epilepsy, Underpinning research, 1.1 Normal biological development and functioning, Aetiology, 2.1 Biological and endogenous factors, Neurological, human brain organoids, neurodevelopmental disorders, mTOR, somatic mutations, cortical development, malformations of cortical development, Clinical Sciences, Biochemistry and cell biology, Biological psychology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/88z3b0q0
https://escholarship.org/content/qt88z3b0q0/qt88z3b0q0.pdf

المؤلفون: Kosillo, Polina, Ahmed, Kamran M, Aisenberg, Erin E, Karalis, Vasiliki, Roberts, Bradley M, Cragg, Stephanie J, Bateup, Helen S

مصطلحات موضوعية: Neurosciences, Underpinning research, 1.1 Normal biological development and functioning, Animals, Dopamine, Dopaminergic Neurons, Mechanistic Target of Rapamycin Complex 1, Mechanistic Target of Rapamycin Complex 2, Mice, TOR Serine-Threonine Kinases, mTORC1, mTORC2, raptor, rictor, dopamine neurons, TSC, Mouse, mouse, neuroscience, Biochemistry and Cell Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/47p0s09p

المؤلفون: Li, Hanqin, Busquets, Oriol, Verma, Yogendra, Syed, Khaja Mohieddin, Kutnowski, Nitzan, Pangilinan, Gabriella R, Gilbert, Luke A, Bateup, Helen S, Rio, Donald C, Hockemeyer, Dirk, Soldner, Frank

مصطلحات موضوعية: Regenerative Medicine, Stem Cell Research - Induced Pluripotent Stem Cell, Genetics, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Stem Cell Research - Embryonic - Human, Biotechnology, Stem Cell Research, Generic health relevance, Humans, RNA, Guide, Kinetoplastida, Gene Editing, Pluripotent Stem Cells, Deoxyribonuclease I, RNA, Messenger, RNA-Directed DNA Polymerase, Ribonucleoproteins, CRISPR-Cas Systems, hPSCs, prime editing, disease models, parkinson's disease, genome engineering, Human, genetics, genomics, human, regenerative medicine, stem cells, Biochemistry and Cell Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9446m3x7
https://escholarship.org/content/qt9446m3x7/qt9446m3x7.pdf

المؤلفون: Benthall, Katelyn N, Cording, Katherine R, Agopyan-Miu, Alexander HCW, Wong, Corinna D, Chen, Emily Y, Bateup, Helen S

المصدر: Cell Reports. 36(6)

مصطلحات موضوعية: Pediatric, Autism, Rare Diseases, Intellectual and Developmental Disabilities (IDD), Behavioral and Social Science, Neurosciences, Brain Disorders, Mental Health, Tuberous Sclerosis, Basic Behavioral and Social Science, Neurological, Mental health, Animals, Corpus Striatum, Endocannabinoids, Gene Deletion, Hypertrophy, Learning, Long-Term Synaptic Depression, Mechanistic Target of Rapamycin Complex 1, Mice, Knockout, Motor Activity, Mutation, Neural Pathways, Neurons, Signal Transduction, Synapses, Synaptic Transmission, Tuberous Sclerosis Complex 1 Protein, Up-Regulation, Tsc1, Tsc2, Tuberous Sclerosis Complex, autism spectrum disorder, corticostriatal synapses, direct pathway, endocannabinoid-LTD, indirect pathway, motor learning, striatum, Biochemistry and Cell Biology, Medical Physiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9fj2m55d

المؤلفون: Kramer, Daniel J, Aisenberg, Erin E, Kosillo, Polina, Friedmann, Drew, Stafford, David A, Lee, Angus Yiu-Fai, Luo, Liqun, Hockemeyer, Dirk, Ngai, John, Bateup, Helen S

المصدر: Cell Reports. 35(6)

مصطلحات موضوعية: Neurosciences, Basic Behavioral and Social Science, Genetics, Behavioral and Social Science, Neurological, Good Health and Well Being, Animals, Cell Line, Dopamine Plasma Membrane Transport Proteins, Dopaminergic Neurons, Humans, Mice, DAT, DAT-dopamine neurons, Flp recombinase, Neurod6, TrailMap, intersectional genetics, nucleus accumbens, substantia nigra pars compacta, ventral tegmental area, Biochemistry and Cell Biology, Medical Physiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8p75h4ps

المؤلفون: Karalis, Vasiliki, Bateup, Helen S

المصدر: Developmental Neuroscience. 43(3-4)

مصطلحات موضوعية: Mental Health, Stem Cell Research, Intellectual and Developmental Disabilities (IDD), Brain Disorders, Stem Cell Research - Nonembryonic - Non-Human, Genetics, Neurosciences, 1.1 Normal biological development and functioning, Underpinning research, Neurological, Animals, Autism Spectrum Disorder, Humans, Mechanistic Target of Rapamycin Complex 1, Mechanistic Target of Rapamycin Complex 2, Mice, Quality of Life, Signal Transduction, Rapamycin, Tuberous sclerosis complex, mTORopathy, Epilepsy, Neurodevelopmental disorders, Raptor, Rictor, PTEN, mTORC1, mTORC2, Paediatrics and Reproductive Medicine, Cognitive Sciences, Neurology & Neurosurgery

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4r689797

المؤلفون: Kosillo, Polina, Bateup, Helen S

مصطلحات موضوعية: Angelman syndrome, Fragile X syndrome, PTEN hamartoma tumor syndrome, Rett syndrome, Tuberous Sclerosis Complex, autism spectrum disorder, dopamine, genetic mouse models, Neurosciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7nk139xg

المؤلفون: Yamashiro, Lívia H, Wilson, Stephen C, Morrison, Huntly M, Karalis, Vasiliki, Chung, Jing-Yi J, Chen, Katherine J, Bateup, Helen S, Szpara, Moriah L, Lee, Angus Y, Cox, Jeffery S, Vance, Russell E

المصدر: Nature communications. 11(1)

مصطلحات موضوعية: Macrophages, Animals, Mice, Inbred C57BL, Mice, Knockout, Mice, Mice, Mutant Strains, Herpesvirus 1, Human, Herpes Simplex, Interferon Type I, Membrane Proteins, Signal Transduction, Point Mutation, Autophagy, Female, Male, Interferon Regulatory Factor-3, Immune Evasion

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8078d249

المؤلفون: Blair, John D, Bateup, Helen S

المصدر: Developmental Dynamics. 249(1)

مصطلحات موضوعية: Stem Cell Research, Stem Cell Research - Induced Pluripotent Stem Cell, Regenerative Medicine, Tuberous Sclerosis, Brain Disorders, Stem Cell Research - Nonembryonic - Human, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Rare Diseases, Neurosciences, Stem Cell Research - Embryonic - Human, Aetiology, Development of treatments and therapeutic interventions, 5.2 Cellular and gene therapies, 2.1 Biological and endogenous factors, Neurological, Animals, Brain, Humans, Neurons, Organoids, Pluripotent Stem Cells, Stem Cells, astrocytes, brain organoids, cortical tuber, CRISPR, Cas9, disease modeling, human pluripotent stem cells, mTOR, neurons, TSC1, TSC2, tuberous sclerosis complex, CRISPR/Cas9, Biological Sciences, Medical and Health Sciences, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/639634g9

المؤلفون: Kosillo, Polina, Doig, Natalie M, Ahmed, Kamran M, Agopyan-Miu, Alexander HCW, Wong, Corinna D, Conyers, Lisa, Threlfell, Sarah, Magill, Peter J, Bateup, Helen S

المصدر: Nature Communications. 10(1)

مصطلحات موضوعية: Mental Health, Brain Disorders, Tuberous Sclerosis, Basic Behavioral and Social Science, Behavioral and Social Science, Rare Diseases, Neurosciences, Neurological, Animals, Axons, Behavior, Animal, Cell Body, Cognition, Corpus Striatum, Dopamine, Dopaminergic Neurons, Gene Knockout Techniques, Hypertrophy, Mechanistic Target of Rapamycin Complex 1, Mice, Motivation, Neuronal Plasticity, Signal Transduction, Tuberous Sclerosis Complex 1 Protein

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/77w0w7zp
https://escholarship.org/content/qt77w0w7zp/qt77w0w7zp.pdf

المؤلفون: Blair, John D, Hockemeyer, Dirk, Bateup, Helen S

المصدر: Nature Medicine. 24(10)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Health Sciences, Stem Cell Research, Stem Cell Research - Induced Pluripotent Stem Cell, Tuberous Sclerosis, Genetics, Neurosciences, Stem Cell Research - Embryonic - Human, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Rare Diseases, Regenerative Medicine, Brain Disorders, Intellectual and Developmental Disabilities (IDD), Neurological, CRISPR-Cas Systems, Cell Line, Cerebral Cortex, Genetic Engineering, Humans, Neuroglia, Neurons, Pluripotent Stem Cells, Spheroids, Cellular, Tuberous Sclerosis Complex 1 Protein, Tuberous Sclerosis Complex 2 Protein, Medical and Health Sciences, Immunology, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4bh1r6jt

المؤلفون: Benthall, Katelyn N, Ong, Stacie L, Bateup, Helen S

المصدر: Cell Reports. 23(11)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Autism, Neurosciences, Behavioral and Social Science, Basic Behavioral and Social Science, Brain Disorders, Intellectual and Developmental Disabilities (IDD), Mental Health, Neurological, Animals, Corpus Striatum, Female, Male, Mechanistic Target of Rapamycin Complex 1, Mice, Mice, Knockout, Neurons, Signal Transduction, Synaptic Transmission, Tuberous Sclerosis Complex 1 Protein, D1, D2, Tsc1, autism spectrum disorder, corticostriatal transmission, excitability, mTOR, striatonigral, striatopallidal, striatum, Medical Physiology, Biological sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9pt869rt

المؤلفون: Kramer, Daniel J, Risso, Davide, Kosillo, Polina, Ngai, John, Bateup, Helen S

المصدر: eNeuro. 5(3)

مصطلحات موضوعية: Mesencephalon, Ventral Tegmental Area, Nucleus Accumbens, Neural Pathways, Animals, Mice, Inbred C57BL, Gastrin-Releasing Peptide, Nerve Tissue Proteins, In Situ Hybridization, Fluorescence, Sequence Analysis, RNA, Female, Male, Basic Helix-Loop-Helix Transcription Factors, Dopaminergic Neurons, Cellular Heterogeneity, Dopamine Neurons, Grp, Neurod6, Retrograde Tracing, Single-Cell RNA-Sequencing, VTA, Neurosciences, 2.1 Biological and endogenous factors, Aetiology, Neurological

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/14f3f8hz
https://escholarship.org/content/qt14f3f8hz/qt14f3f8hz.pdf

المؤلفون: Cording, Katherine R., Bateup, Helen S.

المصدر: Frontiers in Cellular Neuroscience ; volume 17 ; ISSN 1662-5102

الاتاحة: http://dx.doi.org/10.3389/fncel.2023.1270489
https://www.frontiersin.org/articles/10.3389/fncel.2023.1270489/full

المؤلفون: Yang, Hongbin, de Jong, Johannes W, Tak, YeEun, Peck, James, Bateup, Helen S, Lammel, Stephan

المصدر: Neuron. 97(2)

مصطلحات موضوعية: Ventral Tegmental Area, Nucleus Accumbens, Afferent Pathways, Animals, Mice, Inbred C57BL, Mice, Dopamine, Behavior, Animal, Exploratory Behavior, Motivation, Conditioning, Operant, Maze Learning, Reward, Female, Male, Dopaminergic Neurons, GABAergic Neurons, Optogenetics, Channelrhodopsins, GABA, dopamine, mesolimbic, motivation, nucleus accumbens, reward, ventral tegmental area, Basic Behavioral and Social Science, Behavioral and Social Science, Neurosciences, Underpinning research, 1.1 Normal biological development and functioning, Good Health and Well Being, Psychology, Cognitive Sciences, Neurology & Neurosurgery

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2kr7q70s

المؤلفون: Blair, John D, Hockemeyer, Dirk, Doudna, Jennifer A, Bateup, Helen S, Floor, Stephen N

المصدر: Cell Reports. 21(7)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Genetics, Neurosciences, Human Genome, Stem Cell Research - Embryonic - Human, Regenerative Medicine, Stem Cell Research, 1.1 Normal biological development and functioning, Neurological, 3' Untranslated Regions, Cell Line, Cells, Cultured, Gene Expression Regulation, Developmental, Humans, Neural Stem Cells, Neurogenesis, Prosencephalon, Protein Biosynthesis, Proteome, TOR Serine-Threonine Kinases, Transcriptome, RNA, TrIP-seq, cellular differentiation, human stem cell, neural progenitor cell, neurogenesis, neuron, polysome profiling, ribosome profiling, translational control, 3’ Untranslated Regions, Biochemistry and Cell Biology, Medical Physiology, Biological sciences

URL الوصول: https://escholarship.org/uc/item/8rq2098s

المؤلفون: Kulkarni, Rishikesh U, Kramer, Daniel J, Pourmandi, Narges, Karbasi, Kaveh, Bateup, Helen S, Miller, Evan W

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 114(11)

مصطلحات موضوعية: Brain, Neurons, Animals, Humans, Mice, Epilepsy, Disease Models, Animal, Xanthones, Tumor Suppressor Proteins, Photons, Voltage-Sensitive Dye Imaging, Tuberous Sclerosis Complex 1 Protein, fluorescent sensors, two-photon microscopy, voltage imaging, Biotechnology, Neurosciences, Brain Disorders, Neurological

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/74z3q8q1

المؤلفون: Colonna, Marco, Konopka, Genevieve, Liddelow, Shane A., Nowakowski, Tomasz, Awatramani, Rajeshwar, Bateup, Helen S., Cadwell, Cathryn R., Caglayan, Emre, Chen, Jerry L., Gillis, Jesse, Kampmann, Martin, Krienen, Fenna, Marsh, Samuel E., Monje, Michelle, O’Dea, Michael R., Patani, Rickie, Pollen, Alex A., Quintana, Francisco J., Scavuzzo, Marissa, Schmitz, Matthew, Sloan, Steven A., Tesar, Paul J., Tollkuhn, Jessica, Tosches, Maria Antonietta, Urbanek, Madeleine E., Werner, Jonathan M., Bayraktar, Omer A., Gokce, Ozgun, Habib, Naomi

المصدر: Nature Neuroscience; December 2024, Vol. 27 Issue: 12 p2310-2325, 16p

المؤلفون: Haetzel, Laura M., Iafrati, Jillian, Cording, Katherine R., Farhan, Mahmoud, Noveir, Sasan D., Rumbaugh, Gavin, Bateup, Helen S.

المصدر: Journal of Neuroscience; 11/27/2024, Vol. 44 Issue 48, p1-19, 19p

مصطلحات موضوعية: ACTION theory (Psychology), MOTOR neurons, AMPA receptors, GLUTAMATE receptors, AUTISM spectrum disorders, DEVELOPMENTAL delay, DENDRITIC spines, DOPAMINE receptors, RAS oncogenes