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1Academic Journal
المؤلفون: Heleen K. Bronsveld, Marie L. De Bruin, Jelle Wesseling, Joyce Sanders, Ingrid Hofland, Vibeke Jensen, Marloes T. Bazelier, Bas ter Braak, Anthonius de Boer, Peter Vestergaard, Marjanka K. Schmidt
المصدر: BMC Cancer, Vol 18, Iss 1, Pp 1-11 (2018)
مصطلحات موضوعية: Insulin, Insulin growth factor 1 receptor, Diabetes mellitus, Breast cancer, PI3K pathway, MAPK pathway, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
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2Academic Journal
المصدر: PLoS ONE, Vol 8, Iss 8, p e73600 (2013)
وصف الملف: electronic resource
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المؤلفون: Erika Moro, Johannes P Schimming, José V. Castell, Bas ter Braak, Laia Tolosa, Barbara M.A. van Vugt-Lussenburg, Bob van der Water, Teresa Martínez-Sena, Miguel A. Miranda, Sylvia Escher
المساهمون: Publica
المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Archives of Toxicology, 95(6), 2109-2121. Springer Science and Business Media LLC
ARCHIVES OF TOXICOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Archives of Toxicologyمصطلحات موضوعية: Redox-cycling phenols, Plastic seals, 0301 basic medicine, Cytotox CALUX reporter gene assay, Health, Toxicology and Mutagenesis, Diffusion, HepG2 BAC-GFP SRXN1 assay, 010501 environmental sciences, Toxicology, 01 natural sciences, Gas Chromatography-Mass Spectrometry, 03 medical and health sciences, chemistry.chemical_compound, Phenols, Cross-contamination of culture wells, Cell Line, Tumor, Humans, Incubation, 0105 earth and related environmental sciences, Nrf2 CALUX reporter gene assay, Hepatotoxicity, Reproducibility of Results, Hep G2 Cells, General Medicine, In vitro toxicity, In vitro, High-Throughput Screening Assays, Hydroquinones, Quinone, In Vitro Systems, 030104 developmental biology, chemistry, Environmental chemistry, Toxicity, Degradation (geology), Oxidation-Reduction, Redox cycling, Toxicity of phenols, High-content imaging
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المؤلفون: Bob van de Water, Liesanne Wolters, Sylvia E. Le Dévédec, Bas ter Braak, Peter Bouwman, Marije Niemeijer
المصدر: Mutagenesis, 37(2), 130-142
Mutagenesisمصطلحات موضوعية: Test Method, HepG2 BAC GFP, 3D Model, DNA damage, Health, Toxicology and Mutagenesis, Next Generation Risk Assessment (NGRA), Toxicology, medicine.disease_cause, Green fluorescent protein, 03 medical and health sciences, 0302 clinical medicine, Drug Metabolism, Mutagenicity, New Approach Methods (NAMs), Genetics, medicine, Humans, Viability assay, Mode of action, Genetics (clinical), 030304 developmental biology, 0303 health sciences, BTG2, 3D Model, Mutagenicity Tests, Chemistry, DNA Damage, Mutagenicity, In vitro toxicology, High Content Imaging, Hep G2 Cells, HepG2 BAC GFP, In vitro, Biochemistry, Test Method, 030220 oncology & carcinogenesis, Tumor Suppressor Protein p53, Genotoxicity, Mutagens, DNA Damage
وصف الملف: application/pdf
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المؤلفون: Tanja Hansen, Laia Tolosa, Jan G. Hengstler, Richard Maclennan, Paul Walker, Rajinder Gupta, Bob van de Water, Florian Caiment, Leroy Elenschneider, Patrick Guye, Bas ter Braak, Sylvia Escher, Jos C. S. Kleinjans, Marcel H. M. van Herwijnen, Wolfgang Moritz, Yannick Schrooders, Tim Brecklinghaus, Ahmed Ghallab, Tine Tricot, Duncan Hauser, Wiebke Albrecht, Marcel Leist, José V. Castell, Catherine M. Verfaillie
المساهمون: RS: GROW - R1 - Prevention, Toxicogenomics, Publica
المصدر: Archives of Toxicology, 95(2), 573-589. Springer
Archives of toxicology, 95:573-589
Archives of Toxicology
ARCHIVES OF TOXICOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instnameمصطلحات موضوعية: 0301 basic medicine, CellNet, Health, Toxicology and Mutagenesis, Cell, Toxicology, Non-DEGsDTU−, TOXICITY, 0302 clinical medicine, Pathway coverage, Gene Regulatory Networks, Induced pluripotent stem cell, Cells, Cultured, Liver cell, INDUCTION, Liver Neoplasms, In vivo liver, In vitro liver, RNA-seq, CellNet, Non-DEGs, Non-DEGsDTU−, Pathway coverage, High-Throughput Nucleotide Sequencing, Cell Differentiation, Hep G2 Cells, General Medicine, RNA-seq, Non-DEGs DTU, In vivo liver, Non-DEGs, In vitro liver, 3. Good health, In Vitro Systems, medicine.anatomical_structure, DIFFERENTIATION, Liver, 030220 oncology & carcinogenesis, Toxicity, HEPATOTOXICITY, Induced Pluripotent Stem Cells, CellNet, In vitro liver, In vivo liver, Non-DEGs, Non-DEGsDTU-, Pathway coverage, RNA-seq, In Vitro Techniques, Biology, METABOLISM, Models, Biological, PRIMARY HEPATOCYTES, 03 medical and health sciences, In vivo, SYSTEMS, Cell Line, Tumor, ddc:570, medicine, Humans, HEPARG CELLS, Non-DEGs(DTU), Gene Expression Profiling, Computational Biology, PLATFORM, Molecular biology, In vitro, EVOLUTION, 030104 developmental biology, Gene Expression Regulation, Cell culture, Hepatocytes, Transcriptome, Drug metabolism
وصف الملف: application/pdf; Print-Electronic
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المؤلفون: Anja Wilmes, Tobias Strassfeld, Harry Vrieling, Manoj Kumar, Balázs Mihalik, Costanza Rovida, Giorgia Pallocca, Nanette G Vrijenhoek, Ciarán Fisher, Bart van der Burg, Thomas Braunbeck, Xenia Dolde, Alice Krebs, Zofia Janstova, Béla Z. Schmidt, Wiebke Albrecht, Jan G. Hengstler, Tim Brecklinghaus, David A. Fluri, J. J. W. A. Boei, Thomas Exner, Marcel Leist, Tanja Waldmann, Jaffar Kisitu, Anna-Katharina Holzer, Manuel Pastor, Joh Dokler, Andrea Paola Cediel Ulloa, Paul Jennings, Barbara M.A. van Vugt-Lussenburg, Bas ter Braak, Bob van de Water, Anna Forsby, Maja Brajnik, Wolfgang Moritz, Catherine M. Verfaillie, Johannes P Schimming, Rebecca von Hellfeld, Alice Limonciel, Francois Busquet, Julianna Kobolák, Ugis Sarkans, Regina Stöber, Jessica Lundqvist, Andras Dinnyes
المساهمون: Molecular and Computational Toxicology, AIMMS
المصدر: Archives of Toxicology
Archives of Toxicology, 94(7), 2435-2461. Springer Verlag
Archives of Toxicology, 94(7), 2435-2461. SPRINGER HEIDELBERG
Krebs, A, van Vugt-Lussenburg, B M A, Waldmann, T, Albrecht, W, Boei, J, Ter Braak, B, Brajnik, M, Braunbeck, T, Brecklinghaus, T, Busquet, F, Dinnyes, A, Dokler, J, Dolde, X, Exner, T E, Fisher, C, Fluri, D, Forsby, A, Hengstler, J G, Holzer, A-K, Janstova, Z, Jennings, P, Kisitu, J, Kobolak, J, Kumar, M, Limonciel, A, Lundqvist, J, Mihalik, B, Moritz, W, Pallocca, G, Ulloa, A P C, Pastor, M, Rovida, C, Sarkans, U, Schimming, J P, Schmidt, B Z, Stöber, R, Strassfeld, T, van de Water, B, Wilmes, A, van der Burg, B, Verfaillie, C M, von Hellfeld, R, Vrieling, H, Vrijenhoek, N G & Leist, M 2020, ' The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods ', Archives of Toxicology, vol. 94, no. 7, pp. 2435-2461 . https://doi.org/10.1007/s00204-020-02802-6
Archives of Toxicology, 94(7), 2435-2461
Archives of toxicology, 94:2435-2461مصطلحات موضوعية: 0301 basic medicine, Test data generation, Computer science, Health, Toxicology and Mutagenesis, Data validation, HAZARD ASSESSMENT, Toxicology, CELL-CULTURE PRACTICE, Documentation, Policy Making, Cells, Cultured, Zebrafish, media_common, EPITHELIAL-CELLS, General Medicine, data processing, GIVIMP, in vitro toxicology, metadata, nuclear receptor, Test (assessment), Strategy implementation, Europe, Data processing, In Vitro Systems, NEURAL CREST MIGRATION, Life Sciences & Biomedicine, REPRODUCTIVE TOXICITY, Risk Assessment, 03 medical and health sciences, SDG 17 - Partnerships for the Goals, ddc:570, Terminology as Topic, Toxicity Tests, media_common.cataloged_instance, Animals, Humans, European union, Retrospective Studies, In vitro toxicology, Electronic Data Processing, Metadata, Science & Technology, business.industry, 030111 toxicology, Reproducibility of Results, CALUX METHOD, IN-VITRO, Pipeline (software), DRUG DISCOVERY, 030104 developmental biology, Nuclear receptor, DEVELOPMENTAL NEUROTOXICITY DNT, Government Regulation, Software engineering, business, EMBRYONIC STEM-CELLS
وصف الملف: application/pdf; Print-Electronic
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المصدر: Methods in molecular biology (Clifton, N.J.). 1981
مصطلحات موضوعية: Microscopy, Cholestasis, Microscopy, Fluorescence, Hepatocytes, Humans, Hep G2 Cells, Chemical and Drug Induced Liver Injury, Signal Transduction
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المؤلفون: Lysiane Richert, Bas ter Braak, Marije Niemeijer, Bob van de Water, Céline Parmentier, Audrey Baze, Steven Wink, Ruben Boon, Catherine M. Verfaillie, Suzanna Huppelschoten
المصدر: Toxicology in Vitro
Toxicology In Vitro, 73. Elsevier BVمصطلحات موضوعية: Male, 0301 basic medicine, DNA damage, Induced Pluripotent Stem Cells, Cell, Context (language use), Biology, Toxicology, medicine.disease_cause, TOXICITY, Unfolded protein response, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Cellular stress response, medicine, Humans, Transcriptomics, Induced pluripotent stem cell, Aged, Aged, 80 and over, Inflammation, Science & Technology, Liver Neoplasms, Cell Differentiation, Hep G2 Cells, General Medicine, Cell biology, MODEL, DIFFERENTIATION, 030104 developmental biology, medicine.anatomical_structure, Liver, Oxidative stress, 030220 oncology & carcinogenesis, Hepatocytes, Induced pluripotent stem cell derived hepatocytes, hepatocytes, SENSITIVITY, INDUCED HEPATOTOXICITY, Life Sciences & Biomedicine, Induced pluripotent stem cell derived
وصف الملف: Print-Electronic; application/pdf
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المؤلفون: Roxanne E. Kieltyka, Doris Heinrich, Ciqing Tong, Linda van den Berk, Bas ter Braak, Bob van de Water, Joeri A. J. Wondergem, Kwakernaak Markus Cornelis, Tingxian Liu
المصدر: Advanced Healthcare Materials
Advanced Healthcare Materials, 10(11). Wileyمصطلحات موضوعية: hydrogels, HepG2 spheroids, Cell Culture Techniques, Biomedical Engineering, Supramolecular chemistry, Pharmaceutical Science, Peptide, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Biomaterials, 3D cell culture, Spheroids, Cellular, medicine, Humans, squaramide, chemistry.chemical_classification, Matrigel, Quinine, Chemistry, Squaramide, Spheroid, Cell Differentiation, Hydrogels, Hep G2 Cells, 021001 nanoscience & nanotechnology, 0104 chemical sciences, medicine.anatomical_structure, Hepatocyte, Self-healing hydrogels, Biophysics, 0210 nano-technology, supramolecular
وصف الملف: application/pdf
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المصدر: Methods in Molecular Biology
Methods in Molecular Biology-Experimental Cholestasis Research
Methods in Molecular Biology ISBN: 9781493994199مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Gene knockdown, medicine.medical_treatment, Oxidative phosphorylation, Biology, medicine.disease, medicine.disease_cause, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Cytokine, Cholestasis, Live cell imaging, 030220 oncology & carcinogenesis, Cellular stress response, medicine, Oxidative stress
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المؤلفون: Steven Hiemstra, Marije Niemeijer, Bob van de Water, Steven Wink, Bas ter Braak, Wouter den Hollander
المصدر: Methods in Pharmacology and Toxicology ISBN: 9781493976768
مصطلحات موضوعية: Liver injury, Drug, Pathology, medicine.medical_specialty, business.industry, media_common.quotation_subject, Microscopy, medicine, medicine.disease, business, media_common
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12
المؤلفون: Joost B. Beltman, Jan P. Langenberg, Johannes P Schimming, Luc J M Bischoff, Bob van de Water, Isoude A. Kuijper, Bas ter Braak, Daan Noort, Liesanne Wolters
المساهمون: TNO Defensie en Veiligheid
المصدر: Archives of Toxicology
Archives of Toxicology, 93(2), 435-451مصطلحات موضوعية: 0301 basic medicine, Health, Toxicology and Mutagenesis, Cell, 010501 environmental sciences, medicine.disease_cause, Toxicology, 01 natural sciences, environment and public health, Green fluorescent protein, Soft electrophiles, Oxidoreductases Acting on Sulfur Group Donors, Gene knockdown, TS - Technical Sciences, Kelch-Like ECH-Associated Protein 1, Chemistry, Nuclear Proteins, Hep G2 Cells, General Medicine, respiratory system, Observation, Weapon & Protection Systems, Molecular Imaging, Cell biology, Protein Transport, medicine.anatomical_structure, Toxicity, Single-Cell Analysis, MafG Transcription Factor, HepG2, NF-E2-Related Factor 2, Green Fluorescent Proteins, Srxn1, Defence Research, Context (language use), Defence, Safety and Security, digestive system, Nrf2, Xenobiotics, Repeated exposure, 03 medical and health sciences, Live cell imaging, Toxicity Tests, medicine, Humans, MafF Transcription Factor, 0105 earth and related environmental sciences, Dose-Response Relationship, Drug, Maleates, CBRN - CBRN Protection, Hydroquinones, Repressor Proteins, 030104 developmental biology, Cell culture, Oxidative stress
وصف الملف: application/pdf
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13
المؤلفون: Christine L E Siezen, Bas ter Braak, Bob van de Water, Steven Wink, Esmee Koedoot, Jan Willem van der Laan, Chantal Pont
المصدر: Breast cancer research
Breast cancer research, 17, 97. BioMed Central
Breast Cancer Research : BCRمصطلحات موضوعية: medicine.medical_specialty, medicine.medical_treatment, Breast Neoplasms, Biology, Pharmacology, Receptor, IGF Type 1, Mice, Antigens, CD, Cell Line, Tumor, Internal medicine, Insulin receptor substrate, Diabetes Mellitus, medicine, Animals, Humans, Hypoglycemic Agents, Insulin, Insulin-Like Growth Factor I, Mammary Glands, Human, Receptor, Insulin-like growth factor 1 receptor, Medicine(all), GRB10, Epithelial Cells, Receptor, Insulin, IRS2, 3. Good health, Insulin receptor, Endocrinology, MCF-7 Cells, biology.protein, Female, Signal transduction, Research Article, Signal Transduction
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14
المؤلفون: Esmee Koedoot, Bob van de Water, Harry van Steeg, Christine L E Siezen, Ewoud N Speksnijder, Jan Willem van der Laan, Daniela C.F. Salvatori, Bas ter Braak
المصدر: Breast cancer research, 17, 14
Breast Cancer Research : BCR
Breast cancer researchمصطلحات موضوعية: medicine.medical_specialty, Epithelial-Mesenchymal Transition, medicine.medical_treatment, Mammary Neoplasms, Animal, Mice, Transgenic, Biology, medicine.disease_cause, Receptor, IGF Type 1, Mice, Internal medicine, medicine, Animals, Cluster Analysis, Insulin, Epithelial–mesenchymal transition, Insulin-Like Growth Factor I, Extracellular Signal-Regulated MAP Kinases, Protein kinase B, Medicine(all), Kinase, Insulin glargine, Gene Expression Profiling, Body Weight, Milk Proteins, Receptor, Insulin, Endocrinology, Cell Transformation, Neoplastic, Tumor promotion, Female, Signal transduction, Tumor Suppressor Protein p53, Carcinogenesis, Proto-Oncogene Proteins c-akt, medicine.drug, Signal Transduction, Research Article
وصف الملف: application/pdf
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المؤلفون: Duarte M. F. Prazeres, Adriano R. Azzoni, Bas ter Braak, Jonathan De la Vega, Gabriel A. Monteiro
المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USPمصطلحات موضوعية: Reporter gene, Liposome, Chinese hamster ovary cell, Green Fluorescent Proteins, TRANSFECÇÃO, Pharmaceutical Science, Transfection, CHO Cells, DNA, Gene delivery, Biology, Molecular biology, Lipids, Chaotropic agent, Plasmid, Cricetulus, Genes, Reporter, Cricetinae, Zeta potential, Animals, Plasmids
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المصدر: Developmental and comparative immunology. 35(10)
مصطلحات موضوعية: Immunology, Virulence, Porins, medicine.disease_cause, Microbiology, Hemolymph, medicine, Animals, Symbiosis, Pathogen, Escherichia coli, Escherichia coli Infections, Sequence Deletion, Aphid, biology, Escherichia coli K12, Escherichia coli Proteins, food and beverages, Membrane Proteins, Pathogenic bacteria, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, Immunity, Innate, Acyrthosiphon pisum, Gastrointestinal Tract, Aphids, Host-Pathogen Interactions, Reactive Oxygen Species, Protein Kinases, Bacteria, Developmental Biology, Bacterial Outer Membrane Proteins
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17
المؤلفون: Pooja Rao, Christine L E Siezen, Eytan Ruppin, Bas ter Braak, Bob van de Water, Joo Sang Lee, Jan Willem van der Laan, Charlotte Voorhoeve
المصدر: Breast Cancer Research : BCR
Breast cancer research, 19, 14
Breast cancer researchمصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Mammary gland, Tumor initiation, medicine.disease_cause, Hallmarks of cancer, Receptor, IGF Type 1, Insulin-like growth factor, Mice, 0302 clinical medicine, Surgical oncology, IGF1R, Cell Movement, Insulin, Insulin-Like Growth Factor I, Medicine(all), Warburg, Prognosis, Tumor Burden, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Female, Glycolysis, Research Article, Signal Transduction, medicine.medical_specialty, Epithelial-Mesenchymal Transition, Breast Neoplasms, Mice, Transgenic, Biology, 03 medical and health sciences, Internal medicine, Cell Line, Tumor, medicine, Animals, Enhancer of Zeste Homolog 2 Protein, Mammary gland tumor, Insulin-like growth factor 1 receptor, Gene Expression Profiling, 030104 developmental biology, Endocrinology, Glucose, Tumor progression, Mutation, Next-generation sequencing, ras Proteins, Carcinogenesis, Transcriptome, Biomarkers
وصف الملف: application/pdf
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