المؤلفون: Ian R. Kilford, Andy Billinton, Barry Passingham, Anita Chowdhury, Alan Naylor, Adrian Hall, Gerard Martin Paul Giblin, Thomas George Christopher Hayhow, Leanne Cutler, Paul Goldsmith, Susan H. Brown, Alan K. Bristow, D. Anthony Rawlings

المصدر: Bioorganic & Medicinal Chemistry Letters. 18:4027-4032

مصطلحات موضوعية: Central Nervous System, medicine.drug_class, Stereochemistry, Chemistry, Pharmaceutical, Carboxylic acid, Clinical Biochemistry, Carboxylic Acids, Pharmaceutical Science, Carboxamide, Pyrazole, Biochemistry, Chemical synthesis, Inhibitory Concentration 50, Structure-Activity Relationship, chemistry.chemical_compound, Amide, Drug Discovery, medicine, Humans, Receptors, Prostaglandin E, Solubility, Molecular Biology, chemistry.chemical_classification, Molecular Structure, Organic Chemistry, Brain, Isoquinolines, Amides, Receptors, Prostaglandin E, EP1 Subtype, Models, Chemical, chemistry, Drug Design, Pyrazoles, Molecular Medicine, Pharmacophore, Penetrant (biochemical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2756d87d424f2e7f9467bf85e919a5a
https://doi.org/10.1016/j.bmcl.2008.05.118

المؤلفون: Barry Passingham, Adrian Hall, Nicholas Maughan Clayton, Thomas George Christopher Hayhow, Gerard Martin Paul Giblin, Ian R. Kilford, Alan Naylor, Andy Billinton, Susan H. Brown, Paul Goldsmith, Lisa Winyard, David N. Hurst, Anita Chowdhury

المصدر: Bioorganic & Medicinal Chemistry Letters. 18:3392-3399

مصطلحات موضوعية: Central Nervous System, Stereochemistry, Carboxylic acid, Clinical Biochemistry, Analgesic, Pharmaceutical Science, Pharmacology, Pyrazole, Biochemistry, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Amide, Drug Discovery, Animals, Combinatorial Chemistry Techniques, Receptors, Prostaglandin E, Receptor, Molecular Biology, Pain Measurement, chemistry.chemical_classification, Analgesics, Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, Antagonist, Brain, Receptors, Prostaglandin E, EP1 Subtype, Rats, Disease Models, Animal, chemistry, Pyrazoles, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890f8f9caf3f85da5db38c3d3d9149c7
https://doi.org/10.1016/j.bmcl.2008.04.018

المؤلفون: Colin A. Campbell, Alan Wise, Gail Hutley, Barry Passingham, Jason Witherington, Vincent Bordas, Christopher J. Gardner, Sharon Butler, Lee Abberley, Tom D. Heightman, Alison I. Muir, Richard L. Elliott, Fiona McKay, David Kenneth Dean, Ben Powney, Gareth J. Sanger, Manuela Berlanga, Jackie S. Scott, Jill Darton, Kim Winborn, Mark J. Longley, Maite de los Frailes

المصدر: Bioorganicmedicinal chemistry letters. 17(23)

مصطلحات موضوعية: Agonist, medicine.medical_specialty, Indoles, medicine.drug_class, Clinical Biochemistry, Growth hormone secretagogue receptor, Pharmaceutical Science, Receptor agonist activity, Peptide hormone, Biochemistry, Growth hormone secretagogue, Internal medicine, Drug Discovery, medicine, Animals, Humans, Receptors, Ghrelin, Molecular Biology, Gastric emptying, Chemistry, Human Growth Hormone, Organic Chemistry, digestive, oral, and skin physiology, Biological activity, Stereoisomerism, Rats, Endocrinology, Gastric Emptying, Molecular Medicine, Ghrelin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1074c2e9c08ae992306ec4ae9b7f9ca5
https://pubmed.ncbi.nlm.nih.gov/17942309