المؤلفون: Ying Zhai, De-Yi Yang, Ernest Asante-Appiah, Lei Chen, Haiqun Tang, Paul Ingravallo, Amin A. Nomeir, John P. Caldwell, Ling Tong, Guowei Zhou, Wensheng Yu, Yueheng Jiang, Oleg Selyutin, Anilkumar G. Nair, Seong Heon Kim, Rong Liu, Joseph A. Kozlowski, Qingbei Zeng, Stuart B. Rosenblum, Michael P. Dwyer, Rong Kong, Ellen Xia, Sony Agrawal, Robert Mazzola, Bandarpalle B. Shankar, Kerry Keertikar

المصدر: Bioorganic & Medicinal Chemistry Letters. 28:1954-1957

مصطلحات موضوعية: 0301 basic medicine, Genotype, Proline, Silylation, viruses, Clinical Biochemistry, Pharmaceutical Science, Hepacivirus, Viral Nonstructural Proteins, Pharmacology, Virus Replication, Antiviral Agents, Heterocyclic Compounds, 4 or More Rings, Biochemistry, 03 medical and health sciences, Dogs, 0302 clinical medicine, Cytochrome P-450 Enzyme System, Pharmacokinetics, Drug Discovery, Animals, Humans, Potency, NS5A, Molecular Biology, Chemistry, Organic Chemistry, virus diseases, Haplorhini, biochemical phenomena, metabolism, and nutrition, digestive system diseases, In vitro, Rats, Regimen, 030104 developmental biology, Molecular Medicine, 030211 gastroenterology & hepatology, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd2480c8ed858188f3382243eccdd83
https://doi.org/10.1016/j.bmcl.2018.03.049

المؤلفون: Shiying Chen, Wensheng Yu, Joseph A. Kozlowski, Daniel Lundell, Seong Heon Kim, Ling Tong, Shelby Umland, Xiaoda Niu, Vinay Girijavallabhan, Lei Chen, Aneta Kosinski, Guowei Zhou, Mengwei Hu, Neng-Yang Shih, Bandarpalle B. Shankar, De-Yi Yang

المصدر: Bioorganic & Medicinal Chemistry Letters. 27:3704-3708

مصطلحات موضوعية: 0301 basic medicine, Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, Hydantoin, ADAM17 Protein, Pharmacology, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Dogs, Drug Discovery, Animals, Humans, Potency, Prodrugs, Pentanoic Acids, Molecular Biology, Whole blood, chemistry.chemical_classification, Hydantoins, Organic Chemistry, Haplorhini, Prodrug, Tace inhibitor, Rats, Enzyme Activation, 030104 developmental biology, Enzyme, ROC Curve, chemistry, Area Under Curve, Molecular Medicine, Lead compound, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5125137f478242040971d76ea3dc87f8
https://doi.org/10.1016/j.bmcl.2017.07.007

المؤلفون: Guowei Zhou, Liping Yang, Neng-Yang Shih, M. Arshad Siddiqui, Vinay Girijavallabhan, Shiying Chen, Lei Chen, Dansu Li, Peter Orth, Zhuyan Guo, Bandarpalle B. Shankar, Kristin E. Rosner, Wensheng Yu, Ling Tong, Chaoyang Dai, Joseph A. Kozlowski, Aneta Kosinski, Xiaoda Niu, Seong Heon Kim, Daniel Lundell, Shelby Umland, Janeta Popovici-Muller

المصدر: Bioorganic & Medicinal Chemistry Letters. 27:3037-3042

مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Hydantoin, ADAM17 Protein, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Dogs, 0302 clinical medicine, Drug Discovery, Animals, Humans, Potency, Protease Inhibitors, Molecular Biology, Whole blood, chemistry.chemical_classification, Chemistry, Hydantoins, Organic Chemistry, Haplorhini, Rats, Enzyme Activation, 030104 developmental biology, Enzyme, ROC Curve, Area Under Curve, Molecular Medicine, Tumor necrosis factor alpha, Half-Life, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9ae78bb60384e5c554a062fa84b16e
https://doi.org/10.1016/j.bmcl.2017.05.062

المؤلفون: Bin Hu, Ling Tong, Sony Agrawal, Craig A. Coburn, Bandarpalle B. Shankar, Michael P. Dwyer, Bin Zhong, Lei Chen, Shiying Chen, Seong Heon Kim, Stuart B. Rosenblum, Shuai Zan, Karin Bystol, Ian W. Davies, Donna Carr, Ernest Asante-Appiah, Wensheng Yu, Joseph A. Kozlowski, Rebecca T. Ruck, Patricia McMonagle, Anilkumar G. Nair, Rong Liu, Oleg Selyutin, De-Yi Yang, Paul Ingravallo, Tao Ji, Qingbei Zeng, Jinglai Hao, Stephanie Curry, Frederick C. Lahser

المصدر: Bioorganicmedicinal chemistry letters. 26(21)

مصطلحات موضوعية: 0301 basic medicine, Indoles, Proline, Stereochemistry, viruses, Clinical Biochemistry, Pharmaceutical Science, Viral Nonstructural Proteins, 01 natural sciences, Biochemistry, Antiviral Agents, 03 medical and health sciences, Structure-Activity Relationship, Drug Discovery, HCV NS5A Inhibitor, Replicon, NS5A, Molecular Biology, Benzofurans, Indole test, Chemistry, Organic Chemistry, Imidazoles, virus diseases, biochemical phenomena, metabolism, and nutrition, digestive system diseases, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a60cb16436bbb67d5e33f8fd3f828fe7
https://pubmed.ncbi.nlm.nih.gov/27680588

المؤلفون: Guowei Zhou, Ling Tong, Bandarpalle B. Shankar, De-Yi Yang, Rong Liu, Sony Agrawal, Ying Zhai, Rong Kong, Craig A. Coburn, Lei Chen, Qingbei Zeng, Seong Heon Kim, Brian J. Lavey, Kerry Keertikar, Razia Rizvi, Ellen Xia, Michael Wong, Yueheng Jiang, Stuart B. Rosenblum, Wensheng Yu, Ernest Asante-Appiah, Anilkumar G. Nair, Joseph A. Kozlowski, Paul Ingravallo, Amin A. Nomeir, Michael P. Dwyer, Oleg Selyutin

المصدر: Bioorganicmedicinal chemistry letters. 26(16)

مصطلحات موضوعية: 0301 basic medicine, Indoles, Genotype, Hepacivirus, Clinical Biochemistry, Pharmaceutical Science, Viral Nonstructural Proteins, Biochemistry, Antiviral Agents, 03 medical and health sciences, Structure-Activity Relationship, Drug Discovery, Area under curve, Structure–activity relationship, Animals, NS5A, Molecular Biology, Indole test, biology, Chemistry, Organic Chemistry, virus diseases, biology.organism_classification, Virology, digestive system diseases, Rats, 030104 developmental biology, ROC Curve, Area Under Curve, Molecular Medicine, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d95943f585472c6925fcc6867075afb6
https://pubmed.ncbi.nlm.nih.gov/27423481

المؤلفون: Patricia McMonagle, Sony Agrawal, Stuart B. Rosenblum, Ling Tong, Wensheng Yu, Paul Ingravallo, Bandarpalle B. Shankar, Guowei Zhou, Oleg Selyutin, Razia Rizvi, Bin Zhong, Frederick C. Lahser, Rong Liu, Brian J. Lavey, De-Yi Yang, Stephanie Curry, Craig A. Coburn, Laura Rokosz, Michael P. Dwyer, Joseph A. Kozlowski, Lei Chen, Amin A. Nomeir, Donna Carr, Ernest Asante-Appiah, Yueheng Jiang, Anilkumar G. Nair, Seong Heon Kim, Qingbei Zeng, Jinglai Hao, Michael Wong, Bin Hu

المصدر: Bioorganicmedicinal chemistry letters. 26(15)

مصطلحات موضوعية: 0301 basic medicine, Male, Elbasvir, viruses, Clinical Biochemistry, Pharmaceutical Science, Hepacivirus, Microbial Sensitivity Tests, Pharmacology, Viral Nonstructural Proteins, Virus Replication, 01 natural sciences, Biochemistry, Antiviral Agents, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, Drug Discovery, Potency, Structure–activity relationship, Animals, NS5A, Molecular Biology, Benzofurans, Indole test, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Organic Chemistry, Imidazoles, virus diseases, biochemical phenomena, metabolism, and nutrition, Virology, Hepatitis C, digestive system diseases, In vitro, 0104 chemical sciences, Rats, Titer, 030104 developmental biology, chemistry, Aminal, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d736ae1eea6333cd6ded142d2f518f6
https://pubmed.ncbi.nlm.nih.gov/27282742

المؤلفون: Ashok Arasappan, Seong-Heon Kim, Robert C. Reynolds, Cheng Li, Aneta Kosinski, Jeremy Clark, Joseph A. Kozlowski, Ling Tong, Vinay Girijavallabhan, Pinto Patrick A, Lei Chen, F. George Njoroge, Anita T. Fowler, Vishal Verma, Subramaniam Ananthan, Randall R. Rossman, Robert Chase, Neng-Yang Shih, Joseph A. Maddry, John A. Secrist, Cecil D. Kwong, Hollis S. Kezar, Abhijit Roychowdhury, Stephanie Curry, Malcolm MacCoss, Hsueh-Cheng Huang, Razia Rizvi, Frank Bennett, Stephen Gavalas, Yuhua Huang, Francisco Velazquez, Alvarez Carmen S, Feng Geng, Xiao Tong, John J. Piwinski, Regina Huelgas, Bandarpalle B. Shankar, Srikanth Venkatraman

المصدر: Bioorganic & Medicinal Chemistry Letters. 22:3229-3234

مصطلحات موضوعية: Pyrimidine, Stereochemistry, Clinical Biochemistry, Substituent, Pharmaceutical Science, Rodentia, Hepacivirus, Virus Replication, Antiviral Agents, Methylation, Biochemistry, Residue (chemistry), chemistry.chemical_compound, Dogs, Species Specificity, In vivo, Drug Discovery, Animals, Potency, Moiety, Benzothiazoles, Replicon, Molecular Biology, Chemistry, Organic Chemistry, Haplorhini, Pyrimidines, Benzothiazole, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63e593455015b9cae754dc9b1385747b
https://doi.org/10.1016/j.bmcl.2012.03.036

المؤلفون: Xiaolian Xu, Seong Heon Kim, Qingbei Zeng, Joseph A. Kozlowski, Carolyn DiIanni Carroll, Neng-Yang Shih, Baldwin John J, Wensheng Yu, Yueheng Jiang, Guizhen Dong, Yuefei Shao, Brian F. Mcguinness, Gopinadhan N. Anilkumar, Lisa Guise Zawacki, Doug W. Hobbs, Chung-Her Jenh, James W. Hall, Stuart B. Rosenblum, Bandarpalle B. Shankar, De-Yi Yang

المصدر: Bioorganic & Medicinal Chemistry Letters. 21:6982-6986

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Receptors, CXCR3, Clinical Biochemistry, hERG, Pharmaceutical Science, C-C chemokine receptor type 7, C-C chemokine receptor type 6, CCR5 receptor antagonist, Pharmacology, Biochemistry, Piperazines, Inhibitory Concentration 50, Structure-Activity Relationship, Chemokine receptor, stomatognathic system, Drug Discovery, Animals, Structure–activity relationship, cardiovascular diseases, skin and connective tissue diseases, Molecular Biology, Molecular Structure, biology, Chemistry, Organic Chemistry, Rats, stomatognathic diseases, Pyrazines, biology.protein, Molecular Medicine, Receptor antagonist activity, Protein Binding, CCL21

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c65b7371750c0100d6b469612e6fd2f
https://doi.org/10.1016/j.bmcl.2011.09.120

المؤلفون: Peter Orth, Bandarpalle B. Shankar, Daniel Lundell, Corey O. Strickland, Vinay Girijavallabhan, Chaoyang Dai, Joseph A. Kozlowski, Janeta Popovici-Muller, Brian J. Lavey, Jing Sun, Shiying Chen, Dansu Li, John J. Piwinski, Razia Rizvi, M. Arshad Siddiqui, Kristin E. Rosner, Lianyun Zhao, Zhuyan Guo, Wong Michael K C, Neng-Yang Shih, Xiaoda Niu

المصدر: Bioorganic & Medicinal Chemistry Letters. 21:3172-3176

مصطلحات موضوعية: Pyrrolidines, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Biological Availability, Pharmaceutical Science, Carboxamide, ADAM17 Protein, Tartrate, Biochemistry, Chemical synthesis, Pyrrolidine, chemistry.chemical_compound, Oral administration, Amide, Drug Discovery, medicine, Animals, Enzyme Inhibitors, Tartrates, Molecular Biology, chemistry.chemical_classification, Molecular Structure, biology, Organic Chemistry, Amides, Rats, Enzyme Activation, ADAM Proteins, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ffe3fdf02a5dba0580b311b55f7fe2
https://doi.org/10.1016/j.bmcl.2011.01.002

المؤلفون: Bandarpalle B. Shankar, Ling Tong, Himanshu Shah, Wensheng Yu, Jing Sun, De-Yi Yang, Guowei Zhou, Lei Chen, Feltz Robert, Kristin E. Rosner, Xiaoda Niu, Neng-Yang Shih, Shelby Umland, Zhuyan Guo, John J. Piwinski, Seong Heon Kim, Dansu Li, Razia Rizvi, Peter Orth, Aneta Kosinski, Wong Michael K C, Joseph A. Kozlowski, Daniel Lundell, M. Arshad Siddiqui, Brian J. Lavey

المصدر: Bioorganic & Medicinal Chemistry Letters. 20:5286-5289

مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Hydantoin, ADAM17 Protein, Biochemistry, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Hydrolase, Animals, Structure–activity relationship, Enzyme Inhibitors, Molecular Biology, biology, Organic Chemistry, Active site, Biological activity, Rats, ADAM Proteins, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Selectivity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0544f42865077bfcb9c1747073ba2311
https://doi.org/10.1016/j.bmcl.2010.06.134

المؤلفون: Jing Sun, Corey O. Strickland, John P. Caldwell, Kristin E. Rosner, Pauline C. Ting, Bandarpalle B. Shankar, Shiying Chen, David B. Belanger, Gerald W. Shipps, Vinay Girijavallabhan, Guowei Zhou, Brian J. Lavey, Dansu Li, Razia Rizvi, Peter Orth, Neng-Yang Shih, M. Arshad Siddiqui, Zhaoning Zhu, Wensheng Yu, Zhuyan Guo, Zhidan Liu, Maria David, John J. Piwinski, Daniel Lundell, Henry M. Vaccaro, Joe F. Lee, Jim Spitler, Vincent S. Madison, Xiaoda Niu, Chaoyang Dai, Mckittrick Brian A, Joseph A. Kozlowski, Janeta Popovici-Muller, Rob Mazzola

المصدر: Bioorganic & Medicinal Chemistry Letters. 20:4812-4815

مصطلحات موضوعية: Molecular model, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, ADAM17 Protein, Tartrate, Biochemistry, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, Pharmacokinetics, Drug Discovery, medicine, Animals, Computer Simulation, Protease Inhibitors, Tartrates, Molecular Biology, chemistry.chemical_classification, Binding Sites, biology, Organic Chemistry, In vitro, Rats, ADAM Proteins, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b8670bf1029b4ff13b82406eff8483
https://doi.org/10.1016/j.bmcl.2010.06.104

المؤلفون: Ying Zhai, Ellen Xia, Lei Chen, Bandarpalle B. Shankar, Qingbei Zeng, Anilkumar G. Nair, Sony Agrawal, Ronald N. Buckle, Guowei Zhou, Kannan P. Naicker, John P. Caldwell, Ling Tong, Yueheng Jiang, Stuart B. Rosenblum, Wensheng Yu, Kerry Keertikar, Haiqun Tang, Seong Heon Kim, Rong Liu, De-Yi Yang, Paul Ingravallo, Gregory Scott Martin, Samuel A. Vellekoop, Melissa L. Allard, Christian L. Holst, Michael P. Dwyer, Amin A. Nomeir, Robert Mazzola, Polivina Jolicia F Gauuan, Joseph A. Kozlowski, Oleg Selyutin, Rong Kong

المصدر: Bioorganicmedicinal chemistry letters. 26(5)

مصطلحات موضوعية: 0301 basic medicine, Silylation, Genotype, Proline, viruses, Hepacivirus, Clinical Biochemistry, Pharmaceutical Science, Microbial Sensitivity Tests, Pharmacology, Viral Nonstructural Proteins, Virus Replication, 01 natural sciences, Biochemistry, Antiviral Agents, 03 medical and health sciences, Structure-Activity Relationship, Drug Discovery, Potency, Structure–activity relationship, NS5A, Molecular Biology, biology, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Drug discovery, Organic Chemistry, virus diseases, biochemical phenomena, metabolism, and nutrition, Silanes, biology.organism_classification, digestive system diseases, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85586f1ce259c9e4c3146d6078489ecd
https://pubmed.ncbi.nlm.nih.gov/26850003

المؤلفون: R. William Hipkin, Jie Wu, Joseph A. Kozlowski, Waldemar Gonsiorek, Guowei Zhou, James A. Spitler, Neng-Yang Shih, Brian J. Lavey, Charles A. Lunn, Bandarpalle B. Shankar, Razia Rizvi, De-Yi Yang, Tong Ling, Ronald L. Wolin

المصدر: Bioorganic & Medicinal Chemistry Letters. 15:4417-4420

مصطلحات موضوعية: Cannabinoid receptor, Chemistry, Stereochemistry, medicine.medical_treatment, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Ligands, Biochemistry, Chemical synthesis, Sulfone, Receptor, Cannabinoid, CB2, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Cannabinoid receptor type 2, Molecular Medicine, Inverse agonist, lipids (amino acids, peptides, and proteins), Sulfones, Cannabinoid, Selectivity, Receptor, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab5a115c74f454a00e8f100990c5a95
https://doi.org/10.1016/j.bmcl.2005.07.023

المؤلفون: Kirkup Michael P, Bandarpalle B. Shankar, John W. Clader, Keith Huie, Sue-Ing Lin, Harry R. Davis, Douglas S Compton, Stuart W. McCombie, Andrew T. McPhail, Margaret van Heek, Yumibe Nathan P, Razia Rizvi, Sundeep Dugar

المصدر: Bioorganic & Medicinal Chemistry Letters. 6:2069-2072

مصطلحات موضوعية: Stereochemistry, Chemistry, medicine.drug_class, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Metabolic stability, Biochemistry, Drug Discovery, Side chain, medicine, Molecular Medicine, Potency, Cholesterol absorption inhibitor, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e1110e2e0b2531fce1b60f72f94d4e12
https://doi.org/10.1016/0960-894x(96)00365-4

المؤلفون: Ashit K. Ganguly, Stuart W. McCombie, Kirkup Michael P, John W. Clader, Bandarpalle B. Shankar

المصدر: Tetrahedron Letters. 37:4095-4098

مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Organic Chemistry, Drug Discovery, Lactam, Organic chemistry, Reformatsky reaction, Menthol, Biochemistry, Asymmetric induction, Cholesterol absorption

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ed96a0211903eb9cba015891fedc0674
https://doi.org/10.1016/0040-4039(96)00764-2

المؤلفون: Cecil D. Kwong, Stephanie Curry, John A. Secrist, Vinay Girijavallabhan, Pinto Patrick A, Lei Chen, Hsueh-Cheng Huang, Aneta Kosinski, Razia Rizvi, Robert C. Reynolds, Ling Tong, Ashok Arasappan, F. George Njoroge, Subramaniam Ananthan, Frank Bennett, Joseph A. Kozlowski, Vishal Verma, Joseph A. Maddry, Hollis S. Kezar, Malcolm MacCoss, Yuhua Huang, Namita Bansal, Francisco Velazquez, Randall R. Rossman, Xiao Tong, Stephen Gavalas, Seong-Heon Kim, Cheng Li, Robert Chase, Bandarpalle B. Shankar, Srikanth Venkatraman

المصدر: Bioorganicmedicinal chemistry letters. 22(22)

مصطلحات موضوعية: Pyrimidine, Stereochemistry, Clinical Biochemistry, High selectivity, Carbohydrates, Pharmaceutical Science, Biological Availability, Hepacivirus, Virus Replication, Biochemistry, Antiviral Agents, chemistry.chemical_compound, Structure-Activity Relationship, Dogs, Drug Discovery, Animals, Molecular Biology, Geminal, Organic Chemistry, Haplorhini, Rats, Pyrimidines, chemistry, Plasma exposure, Molecular Medicine, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a6f48b123a123044b72874916a54d0
https://pubmed.ncbi.nlm.nih.gov/23036957

المؤلفون: Jacob Valiyaveettil, Vinay Girijavallabhan, Pinto Patrick A, Lei Chen, Seong-Heon Kim, Anita T. Fowler, Cecil D. Kwong, Neng-Yang Shih, Xiao Tong, Cheng Li, Frank Bennett, Namita Bansal, Joseph A. Maddry, Hsueh-Cheng Huang, Subramaniam Ananthan, Ling Tong, Stephanie Curry, Joseph A. Kozlowski, Malcolm MacCoss, Srikanth Venkatraman, Francisco Velazquez, Hollis S. Kezar, Bandarpalle B. Shankar, Alvarez Carmen S, Vishal Verma, Randall R. Rossman, John J. Piwinski, Yuhua Huang, Robert C. Reynolds, Stephen Gavalas, Razia Rizvi, Robert Chase, Aneta Kosinski, Ashok Arasappan, John A. Secrist, Jeremy Clark, F. George Njoroge

المصدر: Bioorganicmedicinal chemistry letters. 22(17)

مصطلحات موضوعية: Pyrimidine, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, RNA-dependent RNA polymerase, Hepacivirus, Ring (chemistry), Virus Replication, Biochemistry, Antiviral Agents, chemistry.chemical_compound, Structure-Activity Relationship, Dogs, Drug Discovery, Potency, Molecule, Animals, Humans, Molecular Biology, Glyceraldehyde 3-phosphate dehydrogenase, biology, Organic Chemistry, Hepatitis C, Rats, Thiazoles, Pyrimidines, chemistry, Benzothiazole, biology.protein, Molecular Medicine, Selectivity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b8f85f4ca4fda22394ea622aca8cb0
https://pubmed.ncbi.nlm.nih.gov/22858143

المؤلفون: Ashit K. Ganguly, Stuart W. McCombie, Kirkup Michael P, Bandarpalle B. Shankar

المصدر: Tetrahedron Letters. 34:7171-7174

مصطلحات موضوعية: chemistry.chemical_classification, Denticity, Benzotriazole, Chemistry, Organic Chemistry, Biochemistry, chemistry.chemical_compound, Nucleophile, Aldose, Drug Discovery, Nucleophilic substitution, Organic chemistry, Stereoselectivity, Triol, Piperidine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::34ee82bd9d306bd2679f04d82e10a06b
https://doi.org/10.1016/s0040-4039(00)79279-3

المؤلفون: Stuart W. McCombie, Oswald Wilson, Kirkup Michael P, Karen Rosinski, Sue-Ing Lin, Robert Bishop, Bandarpalle B. Shankar, Paul Kirschmeier, Emily Dobek, Joanne M. Petrin, Donna Carr

المصدر: Bioorganic & Medicinal Chemistry Letters. 3:1537-1542

مصطلحات موضوعية: chemistry.chemical_classification, biology, Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Thio, Total synthesis, Condensation reaction, Biochemistry, Enzyme, Thiolysis, Enzyme inhibitor, Drug Discovery, biology.protein, Molecular Medicine, Protein kinase A, Molecular Biology, Protein kinase C

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::939084d47bf3f57a87b0aac1ea2e9285
https://doi.org/10.1016/s0960-894x(00)80013-x

المؤلفون: Dennis V. Nazareno, Stuart W. McCombie, Bandarpalle B. Shankar, William A. Metz, Jayaram R. Tagat

المصدر: ChemInform. 22

مصطلحات موضوعية: Acylation, In situ, chemistry.chemical_compound, Aminolysis, Chemistry, Organic chemistry, General Medicine, Methylene, Alkylation, Medicinal chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8fa60e90787d02a7ecd65a6ed47ff836
https://doi.org/10.1002/chin.199152206