المؤلفون: Sin, Yuan Yan, Giblin, Aoife, Judina, Aleksandra, Rujirachaivej, Punchita, Corral, Laura, Glennon, Eliza, Tai, ZhiXian, Feng, Tian, Torres, Eduardo, Zorn, Alina, Gorelik, Julia, Kyurkchieva, Elka, Yenchitsomanus, Pa-thai, Swindlehurst, Cathy, Chan, Kyle, Stirling, David, Baillie, George S.

وصف الملف: text

Relation: https://eprints.gla.ac.uk/343034/1/343034.pdf; Sin, Y. Y. et al. (2024) Targeted protein degradation of PDE4 shortforms by a novel proteolysis targeting chimera. FEBS Journal , (doi:10.1111/febs.17359 ) (PMID:39673076) (Early Online Publication)

الاتاحة: https://eprints.gla.ac.uk/343034/
https://eprints.gla.ac.uk/343034/1/343034.pdf

المؤلفون: Sin, Yuan Yan, Cameron, Ryan T., Schepers, Melissa, MacLeod, Ruth, Wright, Tom A., Paes, Dean, van den Hove, Daniel, Willems, Emily, Vanmierlo, Tim, Prickaerts, Jos, Blair, Connor M., Baillie, George S.

وصف الملف: text

Relation: https://eprints.gla.ac.uk/330058/1/330058.pdf; Sin, Y. Y. et al. (2024) Beta‐amyloid interacts with and activates the long‐form phosphodiesterase PDE4D5 in neuronal cells to reduce cAMP availability. FEBS Letters , 598(13), pp. 1591-1604. (doi:10.1002/1873-3468.14902 ) (PMID:38724485)

الاتاحة: https://eprints.gla.ac.uk/330058/
https://eprints.gla.ac.uk/330058/1/330058.pdf

المؤلفون: Main, Alice, Mary, Sheon, Sin, Yuan Yan, Wright, Tom A., Ling, Jiayue, Blair, Connor M., Smith, Godfrey L., Fuller, Will, Baillie, George S.

وصف الملف: text

Relation: https://eprints.gla.ac.uk/336738/1/336738.pdf; Main, A. , Mary, S. , Sin, Y. Y. , Wright, T. A. , Ling, J. , Blair, C. M. , Smith, G. L. , Fuller, W. and Baillie, G. S. (2024) SUMOylation of cardiac myosin binding protein-C reduces its phosphorylation and results in impaired relaxation following treatment with isoprenaline. International Journal of Biochemistry and Cell Biology , 176, 106668. (doi:10.1016/j.biocel.2024.106668 ) (PMID:39321569)

الاتاحة: https://eprints.gla.ac.uk/336738/
https://eprints.gla.ac.uk/336738/1/336738.pdf

المؤلفون: Cooke, Sean F., Wright, Thomas A., Yan Sin, Yuan, Ling, Jiayue, Kyurkchieva, Elka, Phanthaphol, Nattaporn, Mcskimming, Thomas, Herbert, Katharine, Rebus, Selma, Biankin, Andrew V., Chang, David K., Baillie, George S., Blair, Connor M.

مصطلحات موضوعية: RC0254 Neoplasms. Tumors. Oncology (including Cancer), RM Therapeutics. Pharmacology

وصف الملف: text

Relation: https://ray.yorksj.ac.uk/id/eprint/10698/2/324599.pdf; Cooke, Sean F., Wright, Thomas A., Yan Sin, Yuan, Ling, Jiayue, Kyurkchieva, Elka, Phanthaphol, Nattaporn, Mcskimming, Thomas, Herbert, Katharine ORCID logoorcid:0000-0001-9437-0253 , Rebus, Selma, Biankin, Andrew V., Chang, David K., Baillie, George S. and Blair, Connor M. (2024) Disruption of the pro-oncogenic c-RAF–PDE8A complex represents a differentiated approach to treating KRAS–c-RAF dependent PDAC. Scientific Reports, 14 (1).

الاتاحة: https://ray.yorksj.ac.uk/id/eprint/10698/
https://ray.yorksj.ac.uk/id/eprint/10698/2/324599.pdf
https://doi.org/10.1038/s41598-024-59451-3

المؤلفون: Thongyim, Saruda, Wright, Thomas A., Sattayawat, Pachara, Kaewkod, Thida, Baillie, George S., Tragoolpua, Yingmanee, Jangsutthivorawat, Siriphorn, Panya, Aussara

وصف الملف: text

Relation: https://eprints.gla.ac.uk/330696/2/330696.pdf; Thongyim, S., Wright, T. A., Sattayawat, P., Kaewkod, T., Baillie, G. S. , Tragoolpua, Y., Jangsutthivorawat, S. and Panya, A. (2024) Clinacanthus nutans extract lowers periodontal inflammation under high-glucose conditions via inhibiting NF-κB signaling pathway. Frontiers in Pharmacology , 15, 1410419. (doi:10.3389/fphar.2024.1410419 )

الاتاحة: https://eprints.gla.ac.uk/330696/
https://eprints.gla.ac.uk/330696/2/330696.pdf

المؤلفون: Gardner, Oliver F.W., Bai, Tianshu, Baillie, George S., Ferretti, Patrizia

وصف الملف: text

Relation: https://eprints.gla.ac.uk/329462/1/329462.pdf; Gardner, O. F.W., Bai, T., Baillie, G. S. and Ferretti, P. (2024) Phosphodiesterase 4D activity in acrodysostosis-associated neural pathology: too much or too little? Brain Communications , (doi:10.1093/braincomms/fcae225 ) (Early Online Publication)

الاتاحة: https://eprints.gla.ac.uk/329462/
https://eprints.gla.ac.uk/329462/1/329462.pdf

المؤلفون: Shead, Kyle D., Salyahetdinova, Veneta, Baillie, George S.

وصف الملف: text

Relation: https://eprints.gla.ac.uk/328306/1/328306.pdf; Shead, K. D. , Salyahetdinova, V. and Baillie, G. S. (2024) Charting the importance of Filamin A posttranslational modifications. Biochemical Journal , 481(13), pp. 865-881. (doi:10.1042/BCJ20240121 )

الاتاحة: https://eprints.gla.ac.uk/328306/
https://eprints.gla.ac.uk/328306/1/328306.pdf

المؤلفون: Gardner, Oliver FW, Bai, Tianshu, Baillie, George S, Ferretti, Patrizia

المصدر: Brain Communications , 6 (4) , Article fcae225. (2024)

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Clinical Neurology, Neurosciences, Neurosciences & Neurology, acrodysostosis, PDE4D, cAMP, protein kinase A, CAMP-SPECIFIC PHOSPHODIESTERASE, IDENTIFIES PDE4D MUTATIONS, DEPENDENT PROTEIN-KINASE, VERBAL WORD MEMORY, PRKAR1A MUTATION, CATALYTIC UNIT, GENE, PHOSPHORYLATION, ROFLUMILAST, ACTIVATION

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10195107/1/Gardner%202024%20Review%20accepted%20pre-print%20version.pdf; https://discovery.ucl.ac.uk/id/eprint/10195107/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10195107/1/Gardner%202024%20Review%20accepted%20pre-print%20version.pdf
https://discovery.ucl.ac.uk/id/eprint/10195107/

المؤلفون: Gulliver, Chloe, Busiau, Tara, Byrne, Ashleigh, Findlay, Jane E., Hoffmann, Ralf, Baillie, George S.

المساهمون: Center for Translational Molecular Medicine, Philips Research Americas

المصدر: Molecular Oncology ; volume 18, issue 3, page 707-725 ; ISSN 1574-7891 1878-0261

الاتاحة: http://dx.doi.org/10.1002/1878-0261.13572
https://febs.onlinelibrary.wiley.com/doi/pdf/10.1002/1878-0261.13572

المؤلفون: Gardner, Oliver F W, Bai, Tianshu, Baillie, George S, Ferretti, Patrizia

المساهمون: Great Ormond Street Hospital Charity, National Institute for Health and Care Research Great Ormond Street Hospital Biomedical Research Centre, Medical Research Council

المصدر: Brain Communications ; volume 6, issue 4 ; ISSN 2632-1297

الاتاحة: http://dx.doi.org/10.1093/braincomms/fcae225
https://academic.oup.com/braincomms/advance-article-pdf/doi/10.1093/braincomms/fcae225/58367227/fcae225.pdf
https://academic.oup.com/braincomms/article-pdf/6/4/fcae225/58485038/fcae225.pdf

المؤلفون: Baillie, George S., Sood, Arvind, McPhee, Ian, Gall, Irene, Perry, Stephen J., Lefkowitz, Robert J., Houslay, Miles D.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2022 Apr . 119(17), 1-1.

URL الوصول: https://www.jstor.org/stable/27151519

المؤلفون: Montezano, Augusto C., Kuriakose, Jithin, Hood, Katie Y., Sin, Yuan Yan, Camargo, Livia L., Namkung, Yoon, Castro, Carlos H., Santos, Robson A., Alves-Lopes, Rheure, Tejeda, Gonzalo, Passaglia, Patricia, Basheer, Sehrish, Gallen, Emily, Findlay, Jane E., Awan, Fazli R., Laporte, Stéphane A., MacLean, Margaret R., Baillie, George S., Touyz, Rhian M.

المصدر: Hypertension ; volume 82, issue 2, page 267-281 ; ISSN 0194-911X 1524-4563

الاتاحة: https://doi.org/10.1161/hypertensionaha.124.22693
https://www.ahajournals.org/doi/full/10.1161/HYPERTENSIONAHA.124.22693

المؤلفون: PAES, Dean, SCHEPERS, Melissa, WILLEMS, Emily, ROMBAUT, Ben, TIANE, Assia, Solomina, Yevgeniya, Tibbo, Amy, Blair, Connor, Kyurkchieva, Elka, Baillie, George S., Ricciarelli, Roberta, Brullo, Chiara, Fedele, Ernesto, Bruno, Olga, van den Hove, Daniel, VANMIERLO, Tim, Prickaerts, Jos

المساهمون: PAES, Dean, SCHEPERS, Melissa, WILLEMS, Emily, ROMBAUT, Ben, TIANE, Assia, Solomina, Yevgeniya, Tibbo, Amy, Blair, Connor, Kyurkchieva, Elka, Baillie, George S., Ricciarelli, Roberta, Brullo, Chiara, Fedele, Ernesto, Bruno, Olga, van den Hove, Daniel, VANMIERLO, Tim, Prickaerts, Jos

مصطلحات موضوعية: Alzheimer's disease, CRISPR, Cas9, Phosphodiesterase 4D, APP, PS1

وصف الملف: application/pdf

Relation: CELLULAR AND MOLECULAR LIFE SCIENCES, 80 (7) (Art N° 178); http://hdl.handle.net/1942/40497; 80; 001003638300001

الاتاحة: http://hdl.handle.net/1942/40497
https://doi.org/10.1007/s00018-023-04804-w

المؤلفون: Parsons, Emma C., Baillie, George S., Hoffmann, Ralf

وصف الملف: text

Relation: https://eprints.gla.ac.uk/307795/1/307795.pdf; Parsons, E. C. , Baillie, G. S. and Hoffmann, R. (2023) Revisiting the roles of cAMP signalling in the progression of prostate cancer. Biochemical Journal , 480(20), pp. 1599-1614. (doi:10.1042/BCJ20230297 )

الاتاحة: https://eprints.gla.ac.uk/307795/
https://eprints.gla.ac.uk/307795/1/307795.pdf

المؤلفون: Gulliver, Chloe, Huss, Sebastian, Semjonow, Axel, Baillie, George S., Hoffmann, Ralf

وصف الملف: text

Relation: https://eprints.gla.ac.uk/305426/3/305426.pdf; Gulliver, C. , Huss, S., Semjonow, A., Baillie, G. S. and Hoffmann, R. (2023) Loss of PDE4D7 expression promotes androgen independence, neuroendocrine differentiation, and alterations in DNA repair: implications for therapeutic strategies. British Journal of Cancer , 129(9), pp. 1462-1476. (doi:10.1038/s41416-023-02417-5 ) (PMID:37740039) (PMCID:PMC10628190)

الاتاحة: https://eprints.gla.ac.uk/305426/
https://eprints.gla.ac.uk/305426/3/305426.pdf

المؤلفون: Gulliver, Chloe, Baillie, George S., Hoffmann, Ralf

وصف الملف: text

Relation: https://eprints.gla.ac.uk/303318/3/303318.pdf; Gulliver, C. , Baillie, G. S. and Hoffmann, R. (2023) Reduced PDE4D7 in prostate cancer correlates with genomic downregulation within the upstream PDE4D coding region. Future Science OA , 9(9), (doi:10.2144/fsoa-2023-0064 ) (PMID:37752916) (PMCID:PMC10518809)

الاتاحة: https://eprints.gla.ac.uk/303318/
https://eprints.gla.ac.uk/303318/3/303318.pdf

المؤلفون: Kyurkchieva, Elka, Baillie, George S.

وصف الملف: text

Relation: https://eprints.gla.ac.uk/301257/1/301257.pdf; Kyurkchieva, E. and Baillie, G. S. (2023) Short PDE4 isoforms as drug targets in disease. Frontiers in Bioscience: Landmark , 28(7), 133. (doi:10.31083/j.fbl2807133 ) (PMID:37525918)

الاتاحة: https://eprints.gla.ac.uk/301257/
https://eprints.gla.ac.uk/301257/1/301257.pdf

المؤلفون: Wright, Thomas A., Gemmell, Alistair O., Tejeda, Gonzalo S., Blair, Connor M., Baillie, George S.

وصف الملف: text

Relation: https://eprints.gla.ac.uk/303426/1/303426.pdf; Wright, T. A. , Gemmell, A. O., Tejeda, G. S. , Blair, C. M. and Baillie, G. S. (2023) Cancer: phosphodiesterase type 4C (PDE4C), the forgotten subfamily as a therapeutic target. International Journal of Biochemistry and Cell Biology , 162, 106453. (doi:10.1016/j.biocel.2023.106453 ) (PMID:37499270)

الاتاحة: https://eprints.gla.ac.uk/303426/
https://eprints.gla.ac.uk/303426/1/303426.pdf

المؤلفون: Paes, Dean, Schepers, Melissa, Willems, Emily, Rombaut, Ben, Tiane, Assia, Solomina, Yevgeniya, Tibbo, Amy, Blair, Connor, Kyurkchieva, Elka, Baillie, George S., Ricciarelli, Roberta, Brullo, Chiara, Fedele, Ernesto, Bruno, Olga, van den Hove, Daniel, Vanmierlo, Tim, Prickaerts, Jos

وصف الملف: text

Relation: https://eprints.gla.ac.uk/298141/1/298141.pdf; Paes, D. et al. (2023) Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-β pathology. Cellular and Molecular Life Sciences , 80(7), 178. (doi:10.1007/s00018-023-04804-w ) (PMID:37306762) (PMCID:PMC10261250)

الاتاحة: https://eprints.gla.ac.uk/298141/
https://eprints.gla.ac.uk/298141/1/298141.pdf

المؤلفون: Brown, Alexandra D., Vergunst, Kathleen L., Branch, Makenzie, Blair, Connor M., Dupré, Denis J., Baillie, George S., Langelaan, David N.

وصف الملف: text

Relation: https://eprints.gla.ac.uk/300540/1/300540.pdf; Brown, A. D., Vergunst, K. L., Branch, M., Blair, C. M. , Dupré, D. J., Baillie, G. S. and Langelaan, D. N. (2023) Structural basis of CBP/p300 recruitment by the microphthalmia-associated transcription factor. Biochimica et Biophysica Acta: Molecular Cell Research , (doi:10.1016/j.bbamcr.2023.119520 ) (PMID:37353163) (In Press)

الاتاحة: https://eprints.gla.ac.uk/300540/
https://eprints.gla.ac.uk/300540/1/300540.pdf