المؤلفون: Tabrizi, Sarah J, Leavitt, Blair R, Rosser, Anne, Kordasiewicz, Holly B, Czech, Christian, Swayze, Eric E, Norris, Daniel A, Baumann, Tiffany, Gerlach, Irene, Schobel, Scott A, Paz, Erika, Smith, Anne V, Landwehrmeyer, G Bernhard, Bennett, C Frank, Lane, Roger M, Teams, Phase 1–2a IONIS-HTTRx Study Site, McColgan, Peter, Hensman, Davina, Ghosh, Rhia, Flower, Michael, Libri, Vincenzo, Saunders, Edwina, Raymond, Lynn, Wild, Edward J, Decolongon, Joji, Li, Tuan, Fathinia, Panteha, Lang, Christina, Lewerenz, Jan, Lindenberg, Katrin, Ludolph, Albert C, Schneider, Ariane, Trautmann, Sonja, Uhl, Stefanie, Saft, Carsten, Weydt, Patrick, Kaminski, Barbara, Kaminski, Daniela, Hoffmann, Rainer, von Hein, Sarah M, Muhlack, Siegfried, Gold, Ralf, Collins, Lucy, Mason, Sarah, Scott, Kirsten, Barker, Roger A, Stoker, Tom, Greenland, Julia, Andresen, Katie, Shanmugam, Mohan, Abdelghani, Mowafak, Turgut, Tolga, Peeren, Siofra, Colaco, Olga, Owens, Rebecca, Subin, Sujamole, Blair, Nick F, Spruth, Eike Jakob, Beckmann, Janna, Krug, Henriette, Langenfurth, Anika, Crossley, Diana, Akhtar, Nasreen, Gavin, Jennie, De Souza, Jenny, Massey, Thomas, McLauchlan, Duncan, Craufurd, David, Cousins, Rebecca, Shastin, Dmitri, Peall, Kathryn, Bhatt, Harsh, Davison, Andrew, Bagshawe, Joanne, Gunning, Belinda, Hamandi, Khalid, Priller, Josef, Rickards, Hugh

المصدر: 2019, ' Targeting Huntingtin Expression in Patients with Huntington’s Disease ', New England Journal of Medicine, vol. 380, no. 24, pp. 2307-2316 . https://doi.org/10.1056/NEJMoa1900907
The New England journal of medicine 380(24), 2307-2316 (2019). doi:10.1056/NEJMoa1900907

مصطلحات موضوعية: Adult, Male, congenital, hereditary, and neonatal diseases and abnormalities, Huntingtin, Mutant, HTT(RX), cerebrospinal fluid [Huntingtin Protein], Oligonucleotides, Disease, 030204 cardiovascular system & hematology, HTT protein, human, medicine.disease_cause, 03 medical and health sciences, 0302 clinical medicine, antagonists & inhibitors [Huntingtin Protein], Huntington's disease, cerebrospinal fluid [Oligonucleotides], mental disorders, Huntingtin Protein, Medicine, Humans, In patient, 030212 general & internal medicine, ddc:610, Injections, Spinal, Mutation, Dose-Response Relationship, Drug, business.industry, Nucleotides, genetics [Huntingtin Protein], General Medicine, Middle Aged, medicine.disease, chemical synthesis [Nucleotides], nervous system diseases, drug therapy [Huntington Disease], Huntington Disease, therapeutic use [Oligonucleotides], nervous system, Cancer research, Female, business, Trinucleotide repeat expansion, pharmacology [Nucleotides]

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9b0c3cfd83bb7bd722e3850edd8afa
https://www.pure.ed.ac.uk/ws/files/89496225/nejmoa1900907.pdf

المؤلفون: Fegan, Christopher, Bagshawe, Joanne, Salles, Gilles, Karlin, Lionel, Rule, Simon, Shah, Nimish, Morschhauser, Franck, Terriou, Louis, Dyer, Martin JS, Walter, Harriet, Hutchinson, Claire, Cartron, Guillaume, Sharpe, John, Duffy, Kevin, Nishimura, Akhisa, Abe, Shin-ichiro, Honda, Hideyuki, Yasuhiro, Tomoko, Yoshizawa, Toshio, Birkett, Joseph, Courtenay-Luck, Nigel

المصدر: Blood; December 2014, Vol. 124 Issue: 21 p3328-3328, 1p