المؤلفون: J. Scott Sawyer, Sandra L. Cockerham, K. Jeff Thrasher, Larry L. Froelich, Carlos R. Roman, Bach Nicholas J, Peter W. Stengel, Jerome H. Fleisch, Steven A. Silbaugh

المصدر: Bioorganic & Medicinal Chemistry Letters. 6:249-252

مصطلحات موضوعية: LTD4 receptor, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Quinoline, Pharmaceutical Science, Pharmacology, Biochemistry, In vitro, Guinea pig, chemistry.chemical_compound, Membrane, Orally active, chemistry, In vivo, Drug Discovery, Molecular Medicine, Receptor, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::438717985a22985e2fc666797a7adefa
https://doi.org/10.1016/0960-894x(96)00013-3

المؤلفون: Bach Nicholas J, Dennis R. Berry, Robert D. Dillard, Edward David Mihelich, Jean-Pierre Wery, Cynthia D. Sommers, Lea M. Johnson, David W. Snyder, Donald G. Carlson, David K. Clawson, Emma R. McKinney, Amy C. Smith, Richard Walter Schevitz, Susan E. Draheim, Lawrence W. Hartley, Jennifer L. Olkowski, Noel D. Jones, Nickolay Y. Chirgadze

المصدر: Journal of Medicinal Chemistry. 39:5137-5158

مصطلحات موضوعية: Magnetic Resonance Spectroscopy, medicine.drug_class, Stereochemistry, Carboxamide, Crystallography, X-Ray, Chemical synthesis, Mass Spectrometry, Phospholipases A, Structure-Activity Relationship, Phospholipase A2, Drug Discovery, medicine, Humans, Indole test, chemistry.chemical_classification, Indoleacetic Acids, biology, Active site, Phospholipases A2, Enzyme, chemistry, Biochemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Selectivity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb0858e7cadcd119a6d3f11a160b093
https://doi.org/10.1021/jm960486n

المؤلفون: Robert D. Dillard, Susan E. Draheim, Bach Nicholas J, Cynthia D. Sommers, Amy C. Smith, Emma R. McKinney, Noel D. Jones, Jennifer L. Olkowski, Edward David Mihelich, Jean-Pierre Wery, David W. Snyder, Lawrence W. Hartley, Donald G. Carlson, Richard Walter Schevitz, Nickolay Y. Chirgadze, Dennis R. Berry, David K. Clawson, Lea M. Johnson

المصدر: Journal of Medicinal Chemistry. 39:5159-5175

مصطلحات موضوعية: chemistry.chemical_classification, Indole test, Magnetic Resonance Spectroscopy, biology, Biological activity, Phospholipase, Crystallography, X-Ray, Chemical synthesis, Mass Spectrometry, Phospholipases A, Phospholipases A2, Structure-Activity Relationship, chemistry.chemical_compound, Sulfonylurea Compounds, Enzyme, Phospholipase A2, Biochemistry, chemistry, Biosynthesis, Enzyme inhibitor, Drug Discovery, biology.protein, Humans, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a4d3e2c3e6fd72e60021a3469bd5da
https://doi.org/10.1021/jm960487f

المؤلفون: Lawrence W. Hartley, Bach Nicholas J, David W. Snyder, Edward David Mihelich, Robert D. Dillard, Susan E. Draheim, Jean-Pierre Wery, David K. Clawson, C. Sommers, Donald G. Carlson, Richard Walter Schevitz, Jennifer L. Olkowski, Noel D. Jones, Nickolay Y. Chirgadze

المصدر: Nature Structural Biology

مصطلحات موضوعية: Models, Molecular, Indoles, Protein Conformation, Stereochemistry, Guinea Pigs, Biology, Crystallography, X-Ray, Phospholipases A, Secretory Phospholipase A2, Article, Potassium Chloride, Structure-Activity Relationship, chemistry.chemical_compound, Structural Biology, Animals, Humans, Lung, Molecular Biology, Inflammation, Indole test, chemistry.chemical_classification, Binding Sites, Molecular Structure, Active site, Orders of magnitude (mass), Kinetics, Phospholipases A2, Enzyme, chemistry, Biochemistry, Drug Design, biology.protein, Structure based, Biological Assay, Calcium, lipids (amino acids, peptides, and proteins), Selectivity, Lead compound

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a39496bafe98a1eb877d330d4835647
http://europepmc.org/articles/PMC7097651

المؤلفون: Elisabeth A. Schmittling, William T. Jackson, J. Scott Sawyer, David L. Saussy, S. Richard Baker, Philip Marder, Bach Nicholas J, Larry L. Froelich

المصدر: Bioorganic & Medicinal Chemistry Letters. 4:2077-2082

مصطلحات موضوعية: chemistry.chemical_classification, Molecular model, Chemistry, medicine.drug_class, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Leukotriene B4 receptor, Antagonist, Pharmaceutical Science, respiratory system, Receptor antagonist, Biochemistry, chemistry.chemical_compound, Dicarboxylic acid, Drug Discovery, Xanthone, medicine, Molecular Medicine, lipids (amino acids, peptides, and proteins), Binding site, Receptor, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a98d4753abc9e9b078133a5a20eee6f5
https://doi.org/10.1016/s0960-894x(01)80105-0

المؤلفون: Carlos R. Roman, Floreancig Paul Edward, Sandra L. Cockerham, Baker, Larry L. Froelich, P. Marder, Jerome H. Fleisch, William T. Jackson, Bach Nicholas J, Michael J. Sofia

المصدر: Journal of Medicinal Chemistry. 36:3978-3981

مصطلحات موضوعية: Neutrophils, Leukotriene B4, Bronchoconstriction, Guinea Pigs, Receptors, Leukotriene B4, Tetrazoles, Structure-Activity Relationship, chemistry.chemical_compound, Phenols, Antigens, CD, In vivo, Oral administration, Drug Discovery, Animals, Humans, Lung, Molecular Structure, biology, CD11 Antigens, Cell Membrane, Leukotriene B4 receptor, Biological activity, In vitro, chemistry, Biochemistry, CD18 Antigens, biology.protein, Molecular Medicine, Muscle Contraction, Organic anion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb123c949b12bc1b4783e6a0b1066970
https://doi.org/10.1021/jm00076a029

المؤلفون: Jason Scott Sawyer, Floreancig Paul Edward, D. L. Jun. Saussy, Carlos R. Roman, Peter W. Stengel, Larry L. Froelich, Jerome H. Fleisch, Michael J. Sofia, Bach Nicholas J, Stephen Richard Baker, Sandra L. Cockerham, Stephen M. Spaethe, P. Marder, Elisabeth A. Schmittling, Baldwin Rf, J. A. Palkowitz, P. S. Borromeo, William T. Jackson, Steven A. Silbaugh

المصدر: ChemInform. 27

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Stereochemistry, Leukotriene B4 receptor, Antagonist, General Medicine, Benzoic acid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::47e8e4cc53aea42d384c2441d0759fcd
https://doi.org/10.1002/chin.199610155

المؤلفون: Amy C. Smith, Lea M. Johnson, Robert D. Dillard, Lawrence W. Hartley, Donald G. Carlson, Noel D. Jones, Nickolay Y. Chirgadze, Emma R. McKinney, Richard Walter Schevitz, Susan E. Draheim, Jennifer L. Olkowski, Bach Nicholas J, Dennis R. Berry, David W. Snyder, Jean-Pierre Wery, Cynthia D. Sommers, David K. Clawson, Edward David Mihelich

المصدر: ChemInform. 28

مصطلحات موضوعية: Indole test, Biochemistry, Stereochemistry, Chemistry, General Medicine, Secretory Phospholipase A2

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2dccdd1798a2a7acf8d0453faf4a3f38
https://doi.org/10.1002/chin.199716152

المؤلفون: Donald G. Carlson, Cynthia D. Sommers, Richard Walter Schevitz, Bach Nicholas J, Susan E. Draheim, Edward David Mihelich, Nickolay Y. Chirgadze, Amy C. Smith, Jennifer L. Olkowski, David K. Clawson, Jean-Pierre Wery, Robert D. Dillard, Noel D. Jones, David W. Snyder, Emma R. McKinney, Dennis R. Berry, Lea M. Johnson, Lawrence W. Hartley

المصدر: ChemInform. 28

مصطلحات موضوعية: Indole test, Biochemistry, Chemistry, General Medicine, Secretory Phospholipase A2

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::18953de424a69d0b1c2580eceb94fb59
https://doi.org/10.1002/chin.199716151