المؤلفون: Garrisi, Elena Chiara¹ (AUTHOR) garrisi.elena@mh-hannover.de, Müller, Carsten² (AUTHOR), Ure, Benno¹ (AUTHOR), Carlens, Julia² (AUTHOR), Dingemann, Jens¹ (AUTHOR), Schukfeh, Nagoud¹ (AUTHOR)

المصدر: European Journal of Pediatric Surgery. Feb2025, Vol. 35 Issue 1, p52-59. 8p.

مصطلحات موضوعية: *BRONCHIOLITIS obliterans syndrome, *SURGICAL complications, *LUNG transplantation, *GASTROESOPHAGEAL reflux, *THERAPEUTICS, *FUNDOPLICATION

المؤلفون: Renaud-Picard, Benjamin^1,2,3 (AUTHOR), Moshkelgosha, Sajad^1,2 (AUTHOR), Berra, Gregory^1,2,4 (AUTHOR), Cheung, May⁵ (AUTHOR), Hwang, David⁶ (AUTHOR), Hedley, David⁵ (AUTHOR), Juvet, Stephen^1,2,7 (AUTHOR), Martinu, Tereza^1,2,7 (AUTHOR) tereza.martinu@uhn.ca

المصدر: Journal of Heart & Lung Transplantation. Jan2025, Vol. 44 Issue 1, p118-124. 7p.

مصطلحات موضوعية: *BRONCHIOLITIS obliterans syndrome, *REGULATORY T cells, *LUNG transplantation, *CELL analysis, *IMMUNOLOGIC memory

المؤلفون: Sadowska-Klasa, Alicja^1,2 (AUTHOR) a.sadowska@gumed.edu.pl, Karolak, Wojciech^2,3 (AUTHOR), Piekarska, Agnieszka^1,2 (AUTHOR), Kowalski, Jacek^2,4,5 (AUTHOR), Żegleń, Sławomir^2,6 (AUTHOR), Janowicz, Alicja^2,6 (AUTHOR), Nadolny, Tomasz^2,6 (AUTHOR), Wojarski, Jacek^2,3 (AUTHOR), Zaucha, Jan Maciej^1,2 (AUTHOR)

المصدر: Respiration. Dec2024, p1-8. 8p. 1 Illustration.

مصطلحات موضوعية: *BRONCHIOLITIS obliterans syndrome, *HEMATOPOIETIC stem cell transplantation, *GRAFT versus host disease, *CELL transplantation, *LUNG diseases

المؤلفون: Zhang, Wenxi¹ (AUTHOR), Qiu, Tong¹ (AUTHOR), Metelmann, Isabella B² (AUTHOR), Fritz, Ashley V³ (AUTHOR), Rucker, A Justin⁴ (AUTHOR), Du, Wenxing¹ (AUTHOR), Sef, Davorin⁵ (AUTHOR), Jiao, Wenjie¹ (AUTHOR)

المصدر: European Journal of Cardio-Thoracic Surgery. Dec2024, Vol. 66 Issue 6, p1-7. 7p.

مصطلحات موضوعية: *BRONCHIOLITIS obliterans syndrome, *BRONCHIOLITIS obliterans, *LUNG transplantation, *PROPENSITY score matching, *TREATMENT effectiveness

المؤلفون: Matsudo, Kyoto¹ (AUTHOR), Takamori, Shinkichi^1,2 (AUTHOR), Takenaka, Tomoyoshi¹ (AUTHOR) takenaka.tomoyoshi.473@m.kyushu-u.ac.jp, Shimokawa, Mototsugu³ (AUTHOR), Hashinokuchi, Asato¹ (AUTHOR), Nagano, Taichi¹ (AUTHOR), Kinoshita, Fumihiko¹ (AUTHOR), Akamine, Takaki¹ (AUTHOR), Kohno, Mikihiro¹ (AUTHOR), Toyokawa, Gouji⁴ (AUTHOR), Yoshizumi, Tomoharu¹ (AUTHOR)

المصدر: Transplant International. 2024, p1-9. 9p.

مصطلحات موضوعية: *BRONCHIOLITIS obliterans syndrome, *TUMOR necrosis factors, *LUNG transplantation, *T cells, *HOMOGRAFTS

المؤلفون: Renaud-Picard, Benjamin^1,2,3 (AUTHOR), Berra, Gregory^1,2,4 (AUTHOR), Hwang, David⁵ (AUTHOR), Huszti, Ella⁶ (AUTHOR), Miyamoto, Ei^1,2 (AUTHOR), Berry, Gerald J.⁷ (AUTHOR), Pal, Prodipto⁸ (AUTHOR), Juvet, Stephen^1,2,9 (AUTHOR), Keshavjee, Shaf^1,2,10 (AUTHOR), Martinu, Tereza^1,2,9 (AUTHOR) Tereza.Martinu@uhn.ca

المصدر: Journal of Heart & Lung Transplantation. Oct2024, Vol. 43 Issue 10, p1701-1715. 15p.

مصطلحات موضوعية: *BRONCHIOLITIS obliterans syndrome, *LUNG transplantation, *HOMOGRAFTS, *LUNGS, *TRANSLATIONAL research

المؤلفون: Yeo, Hye Ju^1,2 (AUTHOR) hjyeo@pusan.ac.kr, Kang, Junho³ (AUTHOR) rkdwnsgh2002@nate.com, Kim, Yun Hak^4,5 (AUTHOR) yunhak10510@pusan.ac.kr, Cho, Woo Hyun^1,2 (AUTHOR) chowh@pusan.ac.kr

المصدر: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 19, p10423. 13p.

مصطلحات موضوعية: *BRONCHIOLITIS obliterans syndrome, *FORCED expiratory volume, *LUNG transplantation, *PERIOSTIN, *LUNGS, *HOMOGRAFTS

المؤلفون: Olivieri, Attilio¹ (AUTHOR) a.oliveri@staff.univpm.it, Mancini, Giorgia² (AUTHOR) giorgia.mancini@ospedaliriuniti.marche.it

المصدر: Cells (2073-4409). Sep2024, Vol. 13 Issue 18, p1524. 35p.

مصطلحات موضوعية: *BRONCHIOLITIS obliterans syndrome, *STEM cell transplantation, *MESENCHYMAL stem cells, *LEUCOCYTE elastase, *BIOMARKERS, *ELASTASES

المؤلفون: Neumann, Thomas¹ thomas.neumann@med.uni-greifswald.de, Peters, Nadette¹ nadette.peters@gmx.de, Schneidewind, Laila^1,2 laila.schneidewind@uni-greifswald.de, Krüger, William¹ william.krueger@med.uni-greifswald.de

المصدر: BioMed. Sep2024, Vol. 4 Issue 3, p293-301. 9p.

مصطلحات موضوعية: *EOSINOPHILIA, *BRONCHIOLITIS obliterans syndrome, *VITAMIN D metabolism, *INFECTION, *HOMOGRAFTS, *QUALITY of life

المصدر: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

Other URLs: https://www.incyte.com/our-company/compliance-and-transparency

المصدر: Natural History of Chronic Graft-versus-Host Disease in the Oral Cavity of Patients Following Allogeneic Hematopoietic Stem Cell Transplant and Including Healthy Controls
Mays JW, Fassil H, Edwards DA, Pavletic SZ, Bassim CW. Oral chronic graft-versus-host disease: current pathogenesis, therapy, and research. Oral Dis. 2013 May;19(4):327-46. doi: 10.1111/odi.12028. Epub 2012 Oct 28.
Cooke KR, Luznik L, Sarantopoulos S, Hakim FT, Jagasia M, Fowler DH, van den Brink MRM, Hansen JA, Parkman R, Miklos DB, Martin PJ, Paczesny S, Vogelsang G, Pavletic S, Ritz J, Schultz KR, Blazar BR. The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease. Biol Blood Marrow Transplant. 2017 Feb;23(2):211-234. doi: 10.1016/j.bbmt.2016.09.023. Epub 2016 Oct 3.
Jagasia MH, Greinix HT, Arora M, Williams KM, Wolff D, Cowen EW, Palmer J, Weisdorf D, Treister NS, Cheng GS, Kerr H, Stratton P, Duarte RF, McDonald GB, Inamoto Y, Vigorito A, Arai S, Datiles MB, Jacobsohn D, Heller T, Kitko CL, Mitchell SA, Martin PJ, Shulman H, Wu RS, Cutler CS, Vogelsang GB, Lee SJ, Pavletic SZ, Flowers ME. National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: I. The 2014 Diagnosis and Staging Working Group report. Biol Blood Marrow Transplant. 2015 Mar;21(3):389-401.e1. doi: 10.1016/j.bbmt.2014.12.001. Epub 2014 Dec 18.

المصدر: A Phase 2, Open-Label, Randomized, Multicenter Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host Disease

Other URLs: https://www.incyte.com/our-company/compliance-and-transparency

المصدر: GRAVITAS-309: A Phase 2/3 Study of Itacitinib and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

Other URLs: https://www.incyte.com/our-company/compliance-and-transparency

المؤلفون: Incyte Corporation, Rigel Pharmaceuticals, National Institutes of Health (NIH)

المساهمون: Stefanie Sarantopoulos, MD, PhD., Professor of Medicine

المصدر: Phase I Trial of Ruxolitinib Plus Fostamatinib for the Treatment of Steroid Refractory Chronic Graft Versus Host Disease

المصدر: A Randomized, Double-blind, Multicenter, Phase 3 Study to Evaluate Efficacy and Safety of Belumosudil in Combination With Corticosteroids Versus Placebo in Combination With Corticosteroids in Participants at Least 12 Years of Age With Newly Diagnosed Chronic Graft Versus Host Disease (cGVHD)

المؤلفون: Emory University, Department of Pediatrics

المصدر: Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host Disease
Yang AH, Han MAT, Samala N, Rizvi BS, Marchalik R, Etzion O, Wright EC, Cao L, Hakim FT, Jones E, Kapuria D, Hickstein DD, Fowler D, Kanakry JA, Kanakry CG, Kleiner DE, Koh C, Pavletic SZ, Heller T. Characterization of Hepatic Dysfunction in Subjects Diagnosed With Chronic GVHD by NIH Consensus Criteria. Transplant Cell Ther. 2022 Nov;28(11):747.e1-747.e10. doi: 10.1016/j.jtct.2022.07.017. Epub 2022 Jul 22.
Ruben CL, Pirsl F, Steinberg SM, Holtzman NG, Parsons-Wandell L, Baruffaldi J, Curtis LM, Mitchell SA, Kerep AZ, Cowen EW, Berger A, Joe GO, Datiles MB 3rd, Mays JW, Pavletic SZ. Predictors of hematologic malignancy relapse in patients with advanced chronic graft-versus-host disease. Bone Marrow Transplant. 2021 Jul;56(7):1584-1592. doi: 10.1038/s41409-021-01211-2. Epub 2021 Feb 1.
Katic M, Pirsl F, Steinberg SM, Dobbin M, Curtis LM, Pulanic D, Desnica L, Titarenko I, Pavletic SZ. Vitamin D levels and their associations with survival and major disease outcomes in a large cohort of patients with chronic graft-vs-host disease. Croat Med J. 2016 Jun 30;57(3):276-86. doi: 10.3325/cmj.2016.57.276.
Curtis LM, Datiles MB 3rd, Steinberg SM, Mitchell SA, Bishop RJ, Cowen EW, Mays J, McCarty JM, Kuzmina Z, Pirsl F, Fowler DH, Gress RE, Pavletic SZ. Predictive models for ocular chronic graft-versus-host disease diagnosis and disease activity in transplant clinical practice. Haematologica. 2015 Sep;100(9):1228-36. doi: 10.3324/haematol.2015.124131. Epub 2015 Jun 18.
Bassim CW, Fassil H, Dobbin M, Steinberg SM, Baird K, Cole K, Joe G, Comis LE, Mitchell SA, Grkovic L, Edwards D, Mays JW, Cowen EW, Pulanic D, Williams KM, Gress RE, Pavletic SZ. Malnutrition in patients with chronic GVHD. Bone Marrow Transplant. 2014 Oct;49(10):1300-6. doi: 10.1038/bmt.2014.145. Epub 2014 Jul 14.
Martires KJ, Baird K, Steinberg SM, Grkovic L, Joe GO, Williams KM, Mitchell SA, Datiles M, Hakim FT, Pavletic SZ, Cowen EW. Sclerotic-type chronic GVHD of the skin: clinical risk factors, laboratory markers, and burden of disease. Blood. 2011 Oct 13;118(15):4250-7. doi: 10.1182/blood-2011-04-350249. Epub 2011 Jul 26.
Clark J, Yao L, Pavletic SZ, Krumlauf M, Mitchell S, Turner ML, Cowen EW. Magnetic resonance imaging in sclerotic-type chronic graft-vs-host disease. Arch Dermatol. 2009 Aug;145(8):918-22. doi: 10.1001/archdermatol.2009.78.
Imanguli MM, Swaim WD, League SC, Gress RE, Pavletic SZ, Hakim FT. Increased T-bet+ cytotoxic effectors and type I interferon-mediated processes in chronic graft-versus-host disease of the oral mucosa. Blood. 2009 Apr 9;113(15):3620-30. doi: 10.1182/blood-2008-07-168351. Epub 2009 Jan 23.

المصدر: A Phase III Clinical Trial to Demonstrate Efficacy / Safety of Liposomal Cyclosporine a + Standard of Care (SoC) Vs SoC Alone in Treating Chronic Lung Allograft Dysfunction / Bronchiolitis Obliterans in Patients Post Double Lung Transplant

المصدر: A Phase III, Extension Clinical Trial to Demonstrate Efficacy and Safety of Liposomal Cyclosprine a Via the PARI Investigational EFlow® Device and SoC in Treating Bronchiolitis Obliterans in Patients Post Single or Double Lung Transplant

المصدر: A Phase III Clinical Trial to Demonstrate Efficacy / Safety of Liposomal Cyclosporine a + Standard of Care (SoC) Vs SoC Alone in Treating Chronic Lung Allograft Dysfunction / Bronchiolitis Obliterans in Patients Post Single Lung Transplant

المصدر: A Phase 1/2, Open-Label, Dose Escalation and Dose Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamic Activity, and Efficacy of SNDX- 6352 in Subjects With Active Chronic Graft Versus Host Disease Who Have Received at Least 2 Lines of Prior Therapy