المصدر: Chemistry – A European Journal. 18(33):10382-10392

مصطلحات موضوعية: HERBIMYCIN-A, natural products, RING CLOSING METATHESIS, ORGANIC-SYNTHESIS, CLAISEN REARRANGEMENT, ALPHA, C?C coupling, halogenation, ANSAMYCIN ANTIBIOTICS, synthetic methods, GLYCOLATE ALDOL REACTIONS, BETA-UNSATURATED ESTERS, BRIDGED MACROCYCLIC LACTAMS, ASYMMETRIC-SYNTHESIS, carbenoids, HSP90 MOLECULAR CHAPERONE

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dris___01423::8c4d0c3f1258ab5b623123514b077318
https://doi.org/10.1002/chem.201201600

المؤلفون: Thomas M. Neubauer, Hampel Thomas Armin, Thorsten Bach, Thomas van Leeuwen

المصدر: Chemistry (Weinheim an der Bergstrasse, Germany). 18(33)

مصطلحات موضوعية: HERBIMYCIN-A, Ketone, natural products, Lactams, Macrocyclic, Convergent synthesis, RING CLOSING METATHESIS, Alkenes, CLAISEN REARRANGEMENT, Aldehyde, Catalysis, Stereocenter, chemistry.chemical_compound, C?C coupling, halogenation, Organic chemistry, BETA-UNSATURATED ESTERS, BRIDGED MACROCYCLIC LACTAMS, ASYMMETRIC-SYNTHESIS, Carbenoid, chemistry.chemical_classification, Aldehydes, Molecular Structure, Chemistry, Organic Chemistry, Stereoisomerism, ORGANIC-SYNTHESIS, General Chemistry, Hydroquinones, ALPHA, ANSAMYCIN ANTIBIOTICS, synthetic methods, GLYCOLATE ALDOL REACTIONS, Epimer, Organic synthesis, carbenoids, HSP90 MOLECULAR CHAPERONE, Isopropyl

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54368461e7a1d551cf794af97952983e
https://pubmed.ncbi.nlm.nih.gov/22807045

المؤلفون: McErlean, Christopher S. P., Proisy, Nicolas, Davis, Christopher J., Boland, Nicola A., Sharp, Swee Y., Boxall, Kathy, Slawin, Alexandra M. Z., Workman, Paul, Moody, Christopher J.

المصدر: McErlean , C S P , Proisy , N , Davis , C J , Boland , N A , Sharp , S Y , Boxall , K , Slawin , A M Z , Workman , P & Moody , C J 2007 , ' Synthetic ansamycins prepared by a ring-expanding Claisen rearrangement. Synthesis and biological evaluation of ring and conformational analogues of the Hsp90 molecular chaperone inhibitor geldanamycin ' , Organic & Biomolecular Chemistry , vol. 5 , pp. 531-546 . https://doi.org/10.1039/b615378j

مصطلحات موضوعية: POTENT HEAT-SHOCK-PROTEIN-90 INHIBITORS, BRIDGED MACROCYCLIC LACTAMS, PROTEIN-FOLDING MACHINERY, GLYCOLATE ALDOL REACTIONS, SOLID-SUPPORTED REAGENTS, STRUCTURE-BASED DESIGN, IN-VITRO, CLOSING METATHESIS, CRYSTAL-STRUCTURE, PHENOL OXIDATION

الاتاحة: https://research-portal.st-andrews.ac.uk/en/publications/4b7c5839-06d3-4de9-b128-08e4196e566d
https://doi.org/10.1039/b615378j
http://www.scopus.com/inward/record.url?scp=33846509183&partnerID=8YFLogxK