المؤلفون: Yohn, Samantha, Harvey, Phillip, Brannan, Stephen, Horan, William

مصطلحات موضوعية: M1 receptor, M4 receptor, acetylcholine, cognition, cognitive impairment associated with schizophrenia, muscarinic, schizophrenia

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/66c2v5p1
https://escholarship.org/content/qt66c2v5p1/qt66c2v5p1.pdf

المؤلفون: Horan, William P, Kalali, Amir, Brannan, Stephen K, Drevets, Wayne, Mahableshwarkar, Atul, Rao, Srinivas, Reuteman-Fowler, Corey, Savitz, Adam, Singh, Jaskaran, Walker, Gary, Wendland, Jens R, Harvey, Philip D

المصدر: Schizophrenia Bulletin ; ISSN 0586-7614 1745-1701

الاتاحة: https://doi.org/10.1093/schbul/sbae227
https://academic.oup.com/schizophreniabulletin/advance-article-pdf/doi/10.1093/schbul/sbae227/61625608/sbae227.pdf

المؤلفون: Horan, William P., Targum, Steven D., Claxton, Amy, Kaul, Inder, Yohn, Samantha E., Marder, Stephen R., Miller, Andrew C., Brannan, Stephen K.

المصدر: Schizophrenia Research ; volume 274, page 57-65 ; ISSN 0920-9964

الاتاحة: https://doi.org/10.1016/j.schres.2024.08.001
https://api.elsevier.com/content/article/PII:S0920996424003724?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0920996424003724?httpAccept=text/plain

المؤلفون: Kaul, Inder, Sawchak, Sharon, Walling, David P., Tamminga, Carol A., Breier, Alan, Zhu, Haiyuan, Miller, Andrew C., Paul, Steven M., Brannan, Stephen K.

المساهمون: Psychiatry, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Antipsychotic medications, Xanomeline, Xanomeline-trospium

وصف الملف: application/pdf

Relation: JAMA Psychiatry; Kaul I, Sawchak S, Walling DP, et al. Efficacy and Safety of Xanomeline-Trospium Chloride in Schizophrenia: A Randomized Clinical Trial [published correction appears in JAMA Psychiatry. 2024 Jul 3. doi:10.1001/jamapsychiatry.2024.2002]. JAMA Psychiatry. Published online May 1, 2024. doi:10.1001/jamapsychiatry.2024.0785; https://hdl.handle.net/1805/42636

الاتاحة: https://hdl.handle.net/1805/42636

المؤلفون: Paul, Steven M., Yohn, Samantha E., Brannan, Stephen K., Neugebauer, Nichole M., Breier, Alan

المصدر: Biological Psychiatry ; ISSN 0006-3223

الاتاحة: http://dx.doi.org/10.1016/j.biopsych.2024.03.014
https://api.elsevier.com/content/article/PII:S0006322324011739?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0006322324011739?httpAccept=text/plain

المؤلفون: Kaul, Inder, Sawchak, Sharon, Claxton, Amy, Sauder, Colin, Hassman, Howard H., Kakar, Rishi, Walling, David P., Citrome, Leslie, Zhu, Haiyuan, Miller, Andrew C., Brannan, Stephen K.

المصدر: Schizophrenia; Dec2024, Vol. 10 Issue 1, p1-9, 9p

المؤلفون: Breier, Alan, Brannan, Stephen K., Paul, Steven M., Miller, Andrew C.

المساهمون: Psychiatry, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Healthy volunteers, KarXT, Muscarinic receptor agonist, Pharmacokinetics, Phase 1, Schizophrenia, Tolerability, Trospium, Xanomeline

وصف الملف: application/pdf

Relation: Psychopharmacology; Breier A, Brannan SK, Paul SM, Miller AC. Evidence of trospium's ability to mitigate cholinergic adverse events related to xanomeline: phase 1 study results. Psychopharmacology (Berl). 2023;240(5):1191-1198. doi:10.1007/s00213-023-06362-2; https://hdl.handle.net/1805/37419

الاتاحة: https://hdl.handle.net/1805/37419

المؤلفون: Kott, Alan, Brannan, Stephen, Wang, Xingmei, Daniel, David

المصدر: Schizophrenia Bulletin Open ; volume 4, issue 1 ; ISSN 2632-7899

مصطلحات موضوعية: Psychiatry and Mental health

الاتاحة: http://dx.doi.org/10.1093/schizbullopen/sgad003
https://academic.oup.com/schizbullopen/advance-article-pdf/doi/10.1093/schizbullopen/sgad003/48947784/sgad003.pdf
https://academic.oup.com/schizbullopen/article-pdf/4/1/sgad003/49873350/sgad003.pdf

المؤلفون: Yohn, Samantha E., Harvey, Phillip D., Brannan, Stephen K., Horan, William P.

المصدر: Frontiers in Psychiatry; 2024, p1-15, 15p

مصطلحات موضوعية: MUSCARINIC acetylcholine receptors, CHOLINERGIC receptors, DRUG discovery, COGNITION disorders, SCHIZOPHRENIA

المؤلفون: Dacks, Penny A, Armstrong, Joshua J, Brannan, Stephen K, Carman, Aaron J, Green, Allan M, Kirkman, M Sue, Krakoff, Lawrence R, Kuller, Lewis H, Launer, Lenore J, Lovestone, Simon, Merikle, Elizabeth, Neumann, Peter J, Rockwood, Kenneth, Shineman, Diana W, Stefanacci, Richard G, Velentgas, Priscilla, Viswanathan, Anand, Whitmer, Rachel A, Williamson, Jeff D, Fillit, Howard M

المصدر: Alzheimer's Research & Therapy. 8(1)

مصطلحات موضوعية: Dementia, Patient Safety, Clinical Research, Health Services, Aging, Neurodegenerative, Comparative Effectiveness Research, Cardiovascular, Acquired Cognitive Impairment, Behavioral and Social Science, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Neurosciences, Alzheimer's Disease, Brain Disorders, Neurological, Good Health and Well Being, Cognitive Dysfunction, Humans, Alzheimer’s, Cognitive aging, Cognitive decline, Comorbidity, Comparative effectiveness, Diabetes, Hypertension, Prevention, Repurposing, Medical and Health Sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9518p1f1
https://escholarship.org/content/qt9518p1f1/qt9518p1f1.pdf

المؤلفون: Weiden, Peter J., Breier, Alan, Kavanagh, Sarah, Miller, Andrew C., Brannan, Stephen K., Paul, Steven M.

المساهمون: Psychiatry, School of Medicine

المصدر: Publisher

مصطلحات موضوعية: Positive and Negative Syndrome Scale (PANSS), KarXT (xanomeline-trospium), schizophrenia

وصف الملف: application/pdf

Relation: Journal of Clinical Psychiatry; Weiden, P. J., Breier, A., Kavanagh, S., Miller, A. C., Brannan, S. K., & Paul, S. M. (2022). Antipsychotic Efficacy of KarXT (Xanomeline−Trospium): Post Hoc Analysis of Positive and Negative Syndrome Scale Categorical Response Rates, Time Course of Response, and Symptom Domains of Response in a Phase 2 Study. The Journal of Clinical Psychiatry, 83(3), 40913. https://doi.org/10.4088/JCP.21m14316; https://hdl.handle.net/1805/41844

الاتاحة: https://hdl.handle.net/1805/41844

المؤلفون: Sauder, Colin, Allen, Luke A., Baker, Elizabeth, Miller, Andrew C., Paul, Steven M., Brannan, Stephen K.

المساهمون: Karuna Therapeutics

المصدر: Translational Psychiatry ; volume 12, issue 1 ; ISSN 2158-3188

الاتاحة: http://dx.doi.org/10.1038/s41398-022-02254-9
https://www.nature.com/articles/s41398-022-02254-9.pdf
https://www.nature.com/articles/s41398-022-02254-9

المؤلفون: Correll, Christoph U., Angelov, Angel S., Miller, Andrew C., Weiden, Peter J., Brannan, Stephen K.

المساهمون: Karuna Therapeutics

المصدر: Schizophrenia ; volume 8, issue 1 ; ISSN 2754-6993

الاتاحة: http://dx.doi.org/10.1038/s41537-022-00320-1
https://www.nature.com/articles/s41537-022-00320-1.pdf
https://www.nature.com/articles/s41537-022-00320-1

المؤلفون: Brannan, Stephen K., Cutler, Andrew J., Sawchak, Sharon, Kando, Judith, Miller, Andrew C., Claxton, Amy, Paul, Steven M., Kaul, Inder

المصدر: CNS Spectrums ; volume 29, issue 5, page 515-515 ; ISSN 1092-8529 2165-6509

الاتاحة: https://doi.org/10.1017/s1092852924001901
https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S1092852924001901

المؤلفون: Weiden, Peter J., Novak, Keisha, Watson, Carolyn, Sauder, Colin, Kaul, Inder, Miller, Andrew C., Claxton, Amy, Paul, Steven M., Brannan, Stephen K.

المصدر: CNS Spectrums ; volume 29, issue 5, page 509-509 ; ISSN 1092-8529 2165-6509

الاتاحة: https://doi.org/10.1017/s1092852924001792
https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S1092852924001792

المؤلفون: Kaul, Inder, Citrome, Leslie, Sawchak, Sharon, Kando, Judith, Miller, Andrew C., Paul, Steven M., Brannan, Stephen K.

المصدر: CNS Spectrums ; volume 29, issue 5, page 489-490 ; ISSN 1092-8529 2165-6509

الاتاحة: https://doi.org/10.1017/s1092852924001445
https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S1092852924001445

المؤلفون: Yohn, Samantha E., Horan, William P., Brannan, Stephen K., Paul, Steven M.

المصدر: Biological Psychiatry ; volume 95, issue 10, page S269-S270 ; ISSN 0006-3223

الاتاحة: http://dx.doi.org/10.1016/j.biopsych.2024.02.913
https://api.elsevier.com/content/article/PII:S000632232401014X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S000632232401014X?httpAccept=text/plain

المؤلفون: Horan, William, Claxton, Amy, Targum, Steven D., Yohn, Samantha E., Kaul, Inder, Sawchak, Sharon, Miller, Andrew C., Paul, Steven M., Brannan, Stephen K.

المصدر: Biological Psychiatry ; volume 95, issue 10, page S268-S269 ; ISSN 0006-3223

الاتاحة: http://dx.doi.org/10.1016/j.biopsych.2024.02.911
https://api.elsevier.com/content/article/PII:S0006322324010126?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0006322324010126?httpAccept=text/plain

المؤلفون: Kaul, Inder, Sawchak, Sharon, Correll, Christoph U, Kakar, Rishi, Breier, Alan, Zhu, Haiyuan, Miller, Andrew C, Paul, Steven M, Brannan, Stephen K

المصدر: The Lancet ; volume 403, issue 10422, page 160-170 ; ISSN 0140-6736

الاتاحة: http://dx.doi.org/10.1016/s0140-6736(23)02190-6
https://api.elsevier.com/content/article/PII:S0140673623021906?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0140673623021906?httpAccept=text/plain

المؤلفون: Targum, Steven D., Murphy, Christopher, Breier, Alan, Brannan, Stephen K.

المساهمون: Psychiatry, School of Medicine

المصدر: Publisher

مصطلحات موضوعية: Functional unblinding, PANSS, Paired ratings, Schizophrenia, Surveillance

وصف الملف: application/pdf

Relation: Journal of Psychiatric Research; Targum SD, Murphy C, Breier A, Brannan SK. Site-independent confirmation of primary site-based PANSS ratings in a schizophrenia trial. J Psychiatr Res. 2021;144:241-246. doi:10.1016/j.jpsychires.2021.10.027; https://hdl.handle.net/1805/42014

الاتاحة: https://hdl.handle.net/1805/42014