يعرض 1 - 20 نتائج من 88 نتيجة بحث عن '"BILAG."', وقت الاستعلام: 0.60s تنقيح النتائج
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    Academic Journal
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    Academic Journal

    المساهمون: Prevete, I., Iuliano, A., Cauli, A., Piga, M., Iannone, F., Coladonato, L., Bortoluzzi, A., Silvagni, E., Tani, C., Elefante, E., Doria, A., Iaccarino, L., Franceschini, F., Fredi, M., Conti, F., Spinelli, F. R., Frediani, B., Garcìa, E. G., Scirè, C. A., Zanetti, A., Rozza, D., Carrara, G., Sebastiani, G. D.

    مصطلحات موضوعية: OBJECTIVES: Several studies show that age at onset has an impact on the clinical-serological presentation, comorbidities and disease course of patients with systemic lupus erythematosus (SLE). We evaluated whether, in patients with recent onset SLE, the age at onset correlates with clinical-serological manifestations and with comorbidities. METHODS: We analysed 171 patients with a SLE diagnosis obtained within 12 months of diagnosis enrolled in the Early Lupus project. Based on the age of onset of the first disease symptom, they were stratified into 2 groups: early onset (18–45 years) and late onset (>, 45 years). The analysis was replicated by stratifying patients based on age at diagnosis (fulfillment of ACR classification criteria). Each comparison was made at baseline and at 36 months of follow-up. RESULTS: Baseline: patients with late onset displayed comorbidities (hypertension, dyslipidemia and osteoporosis) more frequently than early onset group. 11.4% of late onset patients had a malignancy in medical history, not recorded in the early onset cohort. The two groups differed neither in organ involvement (domain BILAG) nor in disease activity (ECLAM). Patients with early onset showed a disease with signs of higher serologic activity (higher frequency of anti-dsDNA positivity and lower mean C3 and C4 levels) and had malar rash more frequently than the late onset group (36.2% vs. 18.2%, p=0.042). Similar results were obtained by stratifying patients by age of diagnosis (18-45 years and >, 45 years), except for the higher frequency of discoid rash in the group with age at diagnosis >, 45 years (18% vs. 6.6%, p=0.045). 36 months: the 2 groups of patients independently of the stratification applied did not differ in the accumulation of damage, but showed a different pattern of 8 organ involvement. Musculoskeletal involvement was more frequent both in the late onset group (18.6% vs. 7.3%, p=0.043) and in the group with age at diagnosis >, 45 years (20.4% vs. 5.9%, p=0.009) compared to their counterparts, while renal involvement was more frequent in the group with age at diagnosis 18–45 years (21.4% vs. 6.1%, p=0.03).A sub analysis at 36 months on patients without hypertension and osteoporosis at enrollment showed that patients with older age at onset had a higher frequency of these comorbidities, compared to their counterparts. CONCLUSIONS: In our cohort, younger disease SLE onset seems to correlate with a more active immunological profile, while late onset with a higher incidence of comorbidities.

    Relation: info:eu-repo/semantics/altIdentifier/pmid/35894063; info:eu-repo/semantics/altIdentifier/wos/WOS:000955910000019; volume:41; issue:1; firstpage:145; lastpage:150; numberofpages:6; journal:CLINICAL AND EXPERIMENTAL RHEUMATOLOGY; https://hdl.handle.net/11584/367746; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85147047346; https://www.clinexprheumatol.org/abstract.asp?a=17991

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    Academic Journal
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    Academic Journal
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    Academic Journal

    المساهمون: Inês L, Fredi M, Jesus D, Shumilova A, Franceschini F, Vital Em.

    مصطلحات موضوعية: BILAG, Easy-BILAG, SLE, SLE-DAS, SLEDAI

    Relation: info:eu-repo/semantics/altIdentifier/pmid/37634675; info:eu-repo/semantics/altIdentifier/wos/WOS:001224693600001; journal:AUTOIMMUNITY REVIEWS; https://hdl.handle.net/11379/583086; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85169812954

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    Academic Journal

    المساهمون: Cruciani, Claudio, Zen, Margherita, Gatto, Mariele, Morand, Eric, Doria, Andrea

    Relation: info:eu-repo/semantics/altIdentifier/pmid/38044231; info:eu-repo/semantics/altIdentifier/wos/WOS:001339201800001; journal:BAILLIERE'S BEST PRACTICE & RESEARCH: CLINICAL RHEUMATOLOGY; https://hdl.handle.net/11577/3509247

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    Academic Journal
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    Academic Journal
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    Academic Journal
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    Academic Journal
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    المؤلفون: Basse, Ellen Margrethe, Pagh, Peter

    المصدر: Basse, E M & Pagh, P 2021, ' Beskyttelsen af bilag IV-arter på Amager Fælled ved de indbragte klagers opsættende virkning ', Tidsskrift for Miljø, bind 2021, nr. 9, s. 343-363 .

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=pure_au_____::1f11f650d80543ef10d9601bae85cfa8
    https://pure.au.dk/portal/da/publications/beskyttelsen-af-bilag-ivarter-paa-amager-faelled-ved-de-indbragte-klagers-opsaettende-virkning(3b6bdc1c-502a-409a-8202-6af54fb6e765).html

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    المساهمون: Psychology, Health & Technology

    المصدر: Reumatismo, Vol 70, Iss 2, Pp 85-91 (2018)
    Reumatismo, 70(2), 85-91. Societa Italiana di Reumatologia

    وصف الملف: application/pdf

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    Book

    المصدر: Christensen , C J , Ronold , K O & Thøgersen , M L 2000 , Kalibrering af partielle sikkerhedsfaktorer for udmattelse af vindmøllerotorer. Bilagsrapport . Denmark. Forskningscenter Risoe. Risoe-R , nr. 1204(DA)(bilag) .

    وصف الملف: application/pdf

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    Academic Journal

    المساهمون: The Pennsylvania State University CiteSeerX Archives

    المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/93/2b/Rheumatology_(Oxford)_2009_Dec_24_48(12)_1548-1552.tar.gz

    وصف الملف: application/zip

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    Academic Journal

    المساهمون: Piga, Matteo, Floris, Alberto, Sebastiani, Gian Domenico, Prevete, Imma, Iannone, Florenzo, Coladonato, Laura, Govoni, Marcello, Bortoluzzi, Alessandra, Mosca, Marta, Tani, Chiara, Doria, Andrea, Iaccarino, Luca, Franceschini, Franco, Fredi, Micaela, Conti, Fabrizio, Spinelli, Francesca Romana, Galeazzi, Mauro, Bellisai, Francesca, Zanetti, Anna, Carrara, Greta, Scirè, Carlo Alberto, Mathieu, Alessandro

    Relation: info:eu-repo/semantics/altIdentifier/pmid/31840179; info:eu-repo/semantics/altIdentifier/wos/WOS:000574394600021; volume:59; issue:9; firstpage:2272; lastpage:2281; numberofpages:10; journal:RHEUMATOLOGY; http://hdl.handle.net/11573/1509648; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85083009575

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    المساهمون: Complexe Genetica, RS: NUTRIM - R4 - Gene-environment interaction, RS: NUTRIM - R3 - Respiratory & Age-related Health

    المصدر: Annals of the Rheumatic Diseases, 76(12), 1992-2000. BMJ Publishing Group

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    المساهمون: Piga, M, Floris, A, Sebastiani, G, Prevete, I, Iannone, F, Coladonato, L, Govoni, M, Bortoluzzi, A, Mosca, M, Tani, C, Doria, A, Iaccarino, L, Franceschini, F, Fredi, M, Conti, F, Spinelli, F, Galeazzi, M, Bellisai, F, Zanetti, A, Carrara, G, Scirè, C, Mathieu, A

    وصف الملف: STAMPA