نتائج البحث - "BCL-X(L)"

1

Academic Journal

Anti-proliferative effect of honokiol in oral squamous cancer through the regulation of specificity protein 1

المؤلفون: Kim, Dong-Wook, Ko, Seon Mi, Jeon, Young-Joo, Noh, Young-Woock, Choi, Nag-Jin, Cho, Sung-Dae, Moon, Hong Seop, Cho, Young Sik, Shin, Jae-Chen, Park, Seon-Min, Seo, Kang Seok, Choi, Ji-Young, Chae, Jung-Il, Shim, Jung-Hyun

المساهمون: Cho, Sung-Dae

مصطلحات موضوعية: ENDOTHELIAL GROWTH-FACTOR, KAPPA-B ACTIVATION, BCL-X-L, TRANSCRIPTION FACTOR, CELL-CYCLE, INHIBITS ANGIOGENESIS, MAGNOLIA-OFFICINALIS, INDUCED APOPTOSIS, NATURAL-PRODUCT, DOWN-REGULATION, honokiol, oral squamous cancer cell, specificity protein 1, apoptosis

Relation: International Journal of Oncology, Vol.43 No.4, pp.1103-1110; https://hdl.handle.net/10371/207554; 000324603900017; 2-s2.0-84882438112; 221379

الاتاحة: https://hdl.handle.net/10371/207554
https://doi.org/10.3892/ijo.2013.2028

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2

Academic Journal

Fucoidan induces caspase-dependent apoptosis in MC3 human mucoepidermoid carcinoma cells

المؤلفون: Lee, Hang-Eun, Choi, Eun-Sun, Shin, Ji-Ae, Lee, Syng-Ook, Park, Ki-Soo, Cho, Nam-Pyo, Cho, Sung-Dae

المساهمون: Cho, Sung-Dae

مصطلحات موضوعية: N-TERMINAL KINASE, BCL-X-L, ERK, MCL-1, JNK, ACTIVATION, ANTITUMOR, SURVIVAL, ANGIOGENESIS, INVOLVEMENT, fucoidan, apoptosis, mucoepidermoid carcinoma, extracellular signal-regulated kinase 1, myeloid cell leukemia-1

Time: 2

Relation: Experimental and Therapeutic Medicine, Vol.7 No.1, pp.228-232; https://hdl.handle.net/10371/207499; 000330787500042; 2-s2.0-84887972462; 221376

الاتاحة: https://hdl.handle.net/10371/207499
https://doi.org/10.3892/etm.2013.1368

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3

Academic Journal

Convallaria keiskei as a novel therapeutic alternative for salivary gland cancer treatment by targeting myeloid cell leukemia-1

المؤلفون: Lee, Haeng-Eun, Nam, Jeong-Seok, Shin, Ji-Ae, Hong, In-Sun, Yang, In-Hyoung, You, Myung-Jo, Cho, Sung-Dae

المساهمون: Cho, Sung-Dae

مصطلحات موضوعية: MYC-DEPENDENT APOPTOSIS, BCL-X-L, TRANSLATIONAL CONTROL, DOWN-REGULATION, CERVICAL-CARCINOMA, CARDIAC-GLYCOSIDES, MEDIATED APOPTOSIS, ANTAGONIZES MCL-1, ANTICANCER AGENT, IN-VITRO, salivary gland cancer, apoptosis, Convallaria keiskei (MECK), myeloid cell leukemia-1 (Mcl-1), extracellular signal-regulated kinases 1/2 (ERK1/2)

Relation: Head and Neck, Vol.38, pp.E761-E770; https://hdl.handle.net/10371/206956; 000375116400091; 2-s2.0-84937061162; 221332

الاتاحة: https://hdl.handle.net/10371/206956
https://doi.org/10.1002/hed.24096

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4

Academic Journal

Lentivirus-Mediated BCL-X L Overexpression Inhibits Stem Cell Apoptosis during Ex Vivo Expansion and Provides Competitive Advantage Following Xenotransplantation

المؤلفون: Patricia M. A. Zehnle, Ying Wu, Naile Koleci, Sheila Bohler, Miriam Erlacher

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 7, p 4105 (2024)

مصطلحات موضوعية: hematopoietic stem cells, apoptosis, BCL-2, BCL-X L, caspases, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/7/4105; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/273941eb60884fbc83c0eee8a19ceaa7

الاتاحة: https://doi.org/10.3390/ijms25074105
https://doaj.org/article/273941eb60884fbc83c0eee8a19ceaa7

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5

Academic Journal

Cyclic RGD-containing peptides: in silico exploration against BCL-X(L)

المؤلفون: A. K. Oyebamiji, E. T. Akintayo, C. O. Akintayo, H. O. Aworinde, O. D. Adekunle, S. A. Akintelu

المصدر: The Ukrainian Biochemical Journal, Vol 95, Iss 2, Pp 93-105 (2023)

مصطلحات موضوعية: bcl-x(l), carcinogesis, cyclic rgd peptides, in silico study, modeling, peptide-protein interaction, Biochemistry, QD415-436, Medicine, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://ukrbiochemjournal.org/wp-content/uploads/2023/06/Oyebamiji_95_2.pdf; https://doaj.org/toc/2409-4943; https://doaj.org/toc/2413-5003

URL الوصول: https://doaj.org/article/ce9bee2f2ac248d99ab5c3b76cf60895

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6

Academic Journal

B-Cell Lymphoma 2 (Bcl-2) and Regulation of Apoptosis after Traumatic Brain Injury: A Clinical Perspective

المؤلفون: Deng, Hansen, Yue, John K, Zusman, Benjamin E, Nwachuku, Enyinna L, Abou-Al-Shaar, Hussam, Upadhyayula, Pavan S, Okonkwo, David O, Puccio, Ava M

المصدر: Medicina. 56(6)

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1z94d2v8
https://escholarship.org/content/qt1z94d2v8/qt1z94d2v8.pdf

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7

Academic Journal

The drug efficacy testing in 3D cultures platform identifies effective drugs for ovarian cancer patients

المؤلفون: Åkerlund, Emma, Gudoityte, Greta, Moussaud-Lamodiere, Elisabeth, Lind, Olina, Bwanika, Henri Colyn, Lehti, Kaisa, Salehi, Sahar, Carlson, Joseph, Wallin, Emelie, Fernebro, Josefin, Ostling, Paivi, Kallioniemi, Olli, Joneborg, Ulrika, Seashore-Ludlow, Brinton

المساهمون: Institute for Molecular Medicine Finland

مصطلحات موضوعية: Bcl-x-l, Precision medicine, Models, Cells, Carcinoma, Inhibition, Expression, Resistance, Survival, Reveals, Cancers

وصف الملف: application/pdf

Relation: B.S.L. acknowledges the Swedish Research Council (2021-03420) and Ake Wibergs Stiftelse (M19-0271). OK acknowledges the Knut and Alice Wallenberg Foundation (KAW 2015.0291), and the Swedish Research Council (2017-06095). We acknowledge Tom Erkers for constructive criticism of the manuscript. BioRender was used for the schematic graphics. Rebecka Bergstroem and Johan Lindberg are acknowledged for panel-sequencing of the patient-derived models used in the manuscript. Lidia Moyano-Galceran and Okan Gultekin are acknowledged for collection of several of the patient samples.Open access funding provided by Karolinska Institute; Åkerlund , E , Gudoityte , G , Moussaud-Lamodiere , E , Lind , O , Bwanika , H C , Lehti , K , Salehi , S , Carlson , J , Wallin , E , Fernebro , J , Ostling , P , Kallioniemi , O , Joneborg , U & Seashore-Ludlow , B 2023 , ' The drug efficacy testing in 3D cultures platform identifies effective drugs for ovarian cancer patients ' , npj precision oncology , vol. 7 , no. 1 , 111 . https://doi.org/10.1038/s41698-023-00463-z; http://hdl.handle.net/10138/567946; 04401bca-336c-4c1e-ac6d-5de8391b511e; 001096168300001

الاتاحة: http://hdl.handle.net/10138/567946

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8

Academic Journal

Physiological restraint of Bak by Bcl-x(L) is essential for cell survival

المؤلفون: Erinna Lee, S Grabow, S Chappaz, G Dewson, C Hockings, RM Kluck, MA Debrincat, DH Gray, MT Witkowski, M Evangelista, A Pettikiriarachchi, P Bouillet, RM Lane, PE Czabotar, PM Colman, Brian Smith, BT Kile, Walter Fairlie

مصطلحات موضوعية: Uncategorized, apoptosis, Bcl-2, BH3, Bak, Bcl-x(L)

Relation: https://figshare.com/articles/journal_contribution/Physiological_restraint_of_Bak_by_Bcl-x_L_is_essential_for_cell_survival/22231411

الاتاحة: https://doi.org/10.26181/22231411.v1
https://figshare.com/articles/journal_contribution/Physiological_restraint_of_Bak_by_Bcl-x_L_is_essential_for_cell_survival/22231411

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9

Academic Journal

Bcl-x(L) as prognostic marker and potential therapeutic target in cholangiocarcinoma

المؤلفون: Hoffmeister-Wittmann, P. (Paula), Mock, A. (Andreas), Nichetti, F. (Federico), Korell, F. (Felix), Heilig, C.E. (Christoph E.), Scherr, A.L. (Anna Lena), Günther, M. (Michael), Albrecht, T. (Thomas), Kelmendi, E. (Eblina), Xu, K. (Kaiyu), Nader, L. (Luisa), Kessler, A. (Annika), Schmitt, N. (Nathalie), Fritzsche, S. (Sarah), Weiler, S. (Sofia), Sobol, B. (Benjamin), Stenzinger, A. (Albrecht), Boeck, S. (Stefan), Westphalen, C.B. (Christoph B.), Schulze-Osthoff, K. (Klaus), Trojan, J. (Jörg), Kindler, T. (Thomas), Weichert, W. (Wilko), Spiekermann, K. (Karsten), Bitzer, M. (Michael), Folprecht, G. (Gunnar), Illert, A.L. (Anna L.), Boerries, M. (Melanie), Klauschen, F. (Frederick), Ochsenreiter, S. (Sebastian), Siveke, J. (Jens), Bauer, S. (Sebastian), Glimm, H. (Hanno), Brors, B. (Benedikt), Hüllein, J. (Jennifer), Hübschmann, D. (Daniel), Uhrig, S. (Sebastian), Horak, P. (Peter), Kreutzfeld, S. (Simon), Banales, J.M. (Jesús M.), Springfeld, C. (Christoph), Jäger, D. (Dirk), Schirmacher, P. (Peter), Roessler, S. (Stephanie), Ormanns, S. (Steffen), Goeppert, B. (Benjamin), Fröhling, S. (Stefan), Köhler, B.C. (Bruno C.)

مصطلحات موضوعية: Apoptosis, Bcl-2, Bcl-x(L), Chemotherapy, Cholangiocarcinoma, Mcl-1

وصف الملف: application/pdf

Relation: https://hdl.handle.net/10171/65016

الاتاحة: https://hdl.handle.net/10171/65016

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10

Academic Journal

Specific Targeting of Antiapoptotic Bcl-2 Proteins as a Radiosensitizing Approach in Solid Tumors

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 14; Pages: 7850

مصطلحات موضوعية: Bcl-2, Mc-1, Bcl-x L, radiotherapy, therapy resistance, cell death, synovial sarcoma, head and neck squamous cell carcinoma, non-small-cell lung cancer

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Oncology; https://dx.doi.org/10.3390/ijms23147850

الاتاحة: https://doi.org/10.3390/ijms23147850

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11

Academic Journal

Red Blood Cell BCL-xL Is Required for Plasmodium falciparum Survival: Insights into Host-Directed Malaria Therapies

المؤلفون: Coralie Boulet, Ghizal Siddiqui, Taylah L. Gaynor, Christian Doerig, Darren J. Creek, Teresa G. Carvalho

المصدر: Microorganisms; Volume 10; Issue 4; Pages: 824

مصطلحات موضوعية: BCL-x L, malaria, Plasmodium falciparum, host-directed therapy, red blood cells, host–parasite interaction

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Medical Microbiology; https://dx.doi.org/10.3390/microorganisms10040824

الاتاحة: https://doi.org/10.3390/microorganisms10040824

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12

Platelet intrinsic apoptosis

المؤلفون: Josefsson, Emma, 1976

المصدر: Thrombosis Research. 231:206-213

مصطلحات موضوعية: Cardiology and Cardiovascular Disease, Kardiologi och kardiovaskulära sjukdomar, Platelet, Mitochondria, Apoptosis, Cell death, Lifespan, BCL-X L, cell-death, activation, bcl-2, bax, protein, megakaryocytes, mechanism, thrombin, survival, family, Hematology, Cardiovascular System & Cardiology

URL الوصول: https://gup.ub.gu.se/publication/332851

13

Academic Journal

Structure-Based Design of A‑1293102, a Potent and Selective BCL‑X L Inhibitor

المؤلفون: Zhi-Fu Tao (1637641), Xilu Wang (1637659), Jun Chen (4238), Justin P. Ingram (3156099), Sha Jin (296416), Russell A. Judge (1637671), Peter J. Kovar (1637680), Chang Park (1637656), Chaohong Sun (1637674), Brian D. Wakefield (2406415), Li Zhou (54356), Haichao Zhang (221945), Steven W. Elmore (1637677), Darren C. Phillips (1637665), Andrew S. Judd (2311192), Joel D. Leverson (1738723), Andrew J. Souers (1637668)

Relation: https://figshare.com/articles/journal_contribution/Structure-Based_Design_of_A_1293102_a_Potent_and_Selective_BCL_X_sub_L_sub_Inhibitor/14579650

الاتاحة: https://doi.org/10.1021/acsmedchemlett.1c00162.s001

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14

Academic Journal

Mcl-1 and Bok transmembrane domains : Unexpected players in the modulation of apoptosis

المؤلفون: Lucendo, Estefania, Sancho, Monica, Lolicato, Fabio, Javanainen, Matti, Kulig, Waldemar, Leiva, Diego, Duart, Gerard, Andreu-Fernandez, Vicente, Mingarro, Ismael, Orzaez, Mar

المساهمون: Department of Physics

مصطلحات موضوعية: apoptosis, Bcl-2, Bok, Mcl-1, transmembrane, PROSURVIVAL BCL-2 PROTEINS, GLYCOPHORIN-A DIMERIZATION, HELIX PACKING, BAX, BCL-X(L), MOTIF, LOCALIZATION, MITOCHONDRIA, PATHWAYS, SURVIVAL, Biochemistry, cell and molecular biology, Physical sciences

وصف الملف: application/pdf

Relation: We thank Profs. R. Youle and B. Vogelstein for kindly providing the HCT116 cells; Prof. J. V. Esplugues for kindly providing the HeLa MtDsRed cells; and Prof. T. Kaufmann for kindly providing the shControl and shBok HCT116 cells. This work was supported by Spanish Ministry of Economy and Competitiveness Grant SAF2017-84689-R; Generalitat Valenciana Grant PROMETEO/2019/065. E.L. was supported by Generalitat Valenciana Grant ACIF/2016/019. F.L., M.J., and W.K. wish to thank the CSC-IT Center for Science (Espoo, Finland). M.J. acknowledges the Emil Aaltonen Foundation for support.; Lucendo , E , Sancho , M , Lolicato , F , Javanainen , M , Kulig , W , Leiva , D , Duart , G , Andreu-Fernandez , V , Mingarro , I & Orzaez , M 2020 , ' Mcl-1 and Bok transmembrane domains : Unexpected players in the modulation of apoptosis ' , Proceedings of the National Academy of Sciences of the United States of America , vol. 117 , no. 45 , pp. 27980-27988 . https://doi.org/10.1073/pnas.2008885117; ORCID: /0000-0001-7568-0029/work/86487855; http://hdl.handle.net/10138/329276; 74d6f1d2-3f6d-40cf-991e-cf83cc161b88; 000590738600008

الاتاحة: http://hdl.handle.net/10138/329276

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15

Academic Journal

Assessment of the Oral Delivery of a Myelin Basic Protein Gene Promoter with Antiapoptotic bcl‑x L (pMBP-bcl‑x L ) DNA by Cyclic Peptide Nanotubes with Two Aspect Ratios and Its Biodistribution in the Brain and Spinal Cord

المؤلفون: Jiahorng Liaw (10953195), Wei-Hsien Hsieh (10953198), Shih-Hsun Chiou (10953201), Yu-Shan Huang (847180), Shwu-Fen Chang (761846)

Relation: https://figshare.com/articles/journal_contribution/Assessment_of_the_Oral_Delivery_of_a_Myelin_Basic_Protein_Gene_Promoter_with_Antiapoptotic_bcl_x_sub_L_sub_pMBP-bcl_x_sub_L_sub_DNA_by_Cyclic_Peptide_Nanotubes_with_Two_Aspect_Ratios_and_Its_Biodistribution_in_the_Brain_and_Spinal_Cord/14762850

الاتاحة: https://doi.org/10.1021/acs.molpharmaceut.1c00057.s001

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16

Academic Journal

Structure-Guided Development of Potent Benzoylurea Inhibitors of BCL‑X L and BCL‑2

المؤلفون: Michael J. Roy (6390830), Amelia Vom (1840753), Toru Okamoto (673480), Brian J. Smith (203813), Richard W. Birkinshaw (10709192), Hong Yang (37298), Houda Abdo (10709195), Christine. A. White (10709198), David Segal (4637467), David C. S. Huang (9407262), Jonathan B. Baell (115410), Peter M. Colman (234346), Peter E. Czabotar (1792783), Guillaume Lessene (1738750)

Relation: https://figshare.com/articles/journal_contribution/Structure-Guided_Development_of_Potent_Benzoylurea_Inhibitors_of_BCL_X_sub_L_sub_and_BCL_2/14495297

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c01771.s001

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17

Bcl‐x L as prognostic marker and potential therapeutic target in cholangiocarcinoma

المؤلفون: Paula Hoffmeister‐Wittmann, Andreas Mock, Federico Nichetti, Felix Korell, Christoph E. Heilig, Anna‐Lena Scherr, Michael Günther, Thomas Albrecht, Eblina Kelmendi, Kaiyu Xu, Luisa Nader, Annika Kessler, Nathalie Schmitt, Sarah Fritzsche, Sofia Weiler, Benjamin Sobol, Albrecht Stenzinger, Stefan Boeck, Christoph B. Westphalen, Klaus Schulze‐Osthoff, Jörg Trojan, Thomas Kindler, Wilko Weichert, Karsten Spiekermann, Michael Bitzer, Gunnar Folprecht, Anna L. Illert, Melanie Boerries, Frederick Klauschen, Sebastian Ochsenreither, Jens Siveke, Sebastian Bauer, Hanno Glimm, Benedikt Brors, Jennifer Hüllein, Daniel Hübschmann, Sebastian Uhrig, Peter Horak, Simon Kreutzfeldt, Jesus M. Banales, Christoph Springfeld, Dirk Jäger, Peter Schirmacher, Stephanie Roessler, Steffen Ormanns, Benjamin Goeppert, Stefan Fröhling, Bruno C. Köhler

المصدر: Liver International. 42:2855-2870

مصطلحات موضوعية: Cholangiocarcinoma, Hepatology, Medizin, Chemotherapy, Mcl-1, Apoptosis, Bcl-2, Bcl-x(L)

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d4e69096e2225653be02a227e6063dd
https://doi.org/10.1111/liv.15392

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18

Academic Journal

Implementing Systems Modelling and Molecular Imaging to Predict the Efficacy of BCL-2 Inhibition in Colorectal Cancer Patient-Derived Xenograft Models

المصدر: O'Farrell , A C , Jarzabek , M A , Lindner , A U , Carberry , S , Conroy , E , Miller , I S , Connor , K , Shiels , L , Zanella , E R , Lucantoni , F , Lafferty , A , White , K , Meyer Villamandos , M , Dicker , P , Gallagher , W M , Keek , S A , Sanduleanu , S , Lambin , P , Woodruff , H C , Bertotti , A , Trusolino , L , Byrne , A T & Prehn ....

مصطلحات موضوعية: ABT-199, Venetoclax, colorectal cancer, BCL-2, FOLFOX, PDX, preclinical imaging, radiomics, systems biology, deterministic modelling, CELL-DEATH, COLON-CANCER, APOPTOSIS, BCL-X(L), MITOCHONDRIA, RESISTANCE, RESPONSES, PROTEINS, GROWTH