يعرض 1 - 20 نتائج من 44 نتيجة بحث عن '"BARRISH, J. C."', وقت الاستعلام: 0.57s تنقيح النتائج
  1. 1
    Academic Journal
    Antiviral properties of aminodiol inhibitors against human immunodeficiency virus and protease

    المؤلفون: Bechtold, C M, Patick, A K, Alam, M, Greytok, J, Tino, J A, Chen, P, Gordon, E, Ahmad, S, Barrish, J C, Zahler, R

    المصدر: Antimicrobial Agents and Chemotherapy ; volume 39, issue 2, page 374-379 ; ISSN 0066-4804 1098-6596

    الاتاحة: http://dx.doi.org/10.1128/aac.39.2.374
    https://journals.asm.org/doi/pdf/10.1128/AAC.39.2.374

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  2. 2
    Academic Journal
    Application of structure–metabolism relationships in the identification of a selective endothelin A antagonist, BMS-193884, with favourable pharmacokinetic properties

    المؤلفون: Humphreys, W. G., Obermeier, M. T., Barrish, J. C., Chong, S., Marino, A. M., Murugesan, N., Wang-Iverson, D., Morrison, R. A.

    المصدر: Xenobiotica ; volume 33, issue 11, page 1109-1123 ; ISSN 0049-8254 1366-5928

    الاتاحة: http://dx.doi.org/10.1080/00498250310001609147
    http://www.tandfonline.com/doi/pdf/10.1080/00498250310001609147

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  3. 3
    Academic Journal
    ChemInform Abstract: A Practical Method for the Preparation of α′‐Chloroketones of N‐ Carbamate Protected‐α‐Amino Acids.

    المؤلفون: CHEN, P., CHENG, P. T. W., SPERGEL, S. H., ZAHLER, R., WANG, X., THOTTATHIL, J., BARRISH, J. C., POLNIASZEK, R. P.

    المصدر: ChemInform ; volume 28, issue 33 ; ISSN 0931-7597 1522-2667

    الاتاحة: http://dx.doi.org/10.1002/chin.199733267
    https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchin.199733267
    https://onlinelibrary.wiley.com/doi/pdf/10.1002/chin.199733267

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  4. 4
    Academic Journal
    ChemInform Abstract: Mercaptoacyl Dipeptides as Dual Inhibitors of Angiotensin‐Converting Enzyme and Neutral Endopeptidase. Preliminary Structure‐Activity Studies.

    المؤلفون: DELANEY, N. G., BARRISH, J. C., NEUBECK, R., NATARAJAN, S., COHEN, M., ROVNYAK, G. C., HUBER, G., MURUGESAN, N., GIROTRA, R., SIEBER‐MCMASTER, E., ROBL, J. A., ASAAD, M. M., CHEUNG, H. S., BIRD, J. E., WALDRON, T., PETRILLO, E. W.

    المصدر: ChemInform ; volume 26, issue 6 ; ISSN 0931-7597 1522-2667

    الاتاحة: http://dx.doi.org/10.1002/chin.199506220
    https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchin.199506220
    https://onlinelibrary.wiley.com/doi/pdf/10.1002/chin.199506220

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  5. 5
    Academic Journal
    ChemInform Abstract: Dual Metalloprotease Inhibitors. Part 3. Utilization of Bicyclic and Monocyclic Diazepinone Based Mercaptoacetyls.

    المؤلفون: ROBL, J. A., SUN, C.‐Q., SIMPKINS, L. M., RYONO, D. E., BARRISH, J. C., KARANEWSKY, D. S., ASAAD, M. M., SCHAEFFER, T. R., TRIPPODO, N. C.

    المصدر: ChemInform ; volume 26, issue 9 ; ISSN 0931-7597 1522-2667

    الاتاحة: http://dx.doi.org/10.1002/chin.199509216
    https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchin.199509216
    https://onlinelibrary.wiley.com/doi/pdf/10.1002/chin.199509216

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  6. 6
    Academic Journal
    Characterization of a human immunodeficiency virus type 1 variant with reduced sensitivity to an aminodiol protease inhibitor

    المؤلفون: Patick, A K, Rose, R, Greytok, J, Bechtold, C M, Hermsmeier, M A, Chen, P T, Barrish, J C, Zahler, R, Colonno, R J, Lin, P F

    المصدر: Journal of Virology ; volume 69, issue 4, page 2148-2152 ; ISSN 0022-538X 1098-5514

    الاتاحة: http://dx.doi.org/10.1128/jvi.69.4.2148-2152.1995
    https://journals.asm.org/doi/pdf/10.1128/jvi.69.4.2148-2152.1995

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  7. 7
    Academic Journal
    ChemInform Abstract: Aminodiol HIV Protease Inhibitors. Part 1. Design, Synthesis, and Preliminary SAR.

    المؤلفون: BARRISH, J. C., GORDON, E., ALAM, M., LIN, P.‐F., BISACCHI, G. S., CHEN, P., CHENG, P. T. W., FRITZ, A. W., GREYTOK, J. A., HERMSMEIER, M. A., HUMPHREYS, W. G., LIS, K. A., MARELLA, M. A., MERCHANT, Z., MITT, T., MORRISON, R. A., OBERMEIER, M. T., PLUSCEC, J., SKOOG, M., SLUSARCHYK, W. A., SPERGEL, S. H., ET AL., ET AL.

    المصدر: ChemInform ; volume 25, issue 44 ; ISSN 0931-7597 1522-2667

    الاتاحة: http://dx.doi.org/10.1002/chin.199444198
    https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchin.199444198
    https://onlinelibrary.wiley.com/doi/pdf/10.1002/chin.199444198

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  8. 8
    Academic Journal
    ChemInform Abstract: Cupric Bromide Mediated Oxidation of 4‐Carboxyoxazolines to the Corresponding Oxazoles.

    المؤلفون: BARRISH, J. C., SINGH, J., SPERGEL, S. H., HAN, W.‐C., KISSICK, T. P., KRONENTHAL, D. R., MUELLER, R. H.

    المصدر: ChemInform ; volume 24, issue 49 ; ISSN 0931-7597 1522-2667

    الاتاحة: http://dx.doi.org/10.1002/chin.199349179
    https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchin.199349179
    https://onlinelibrary.wiley.com/doi/pdf/10.1002/chin.199349179

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  9. 9
    Academic Journal
    ChemInform Abstract: The Synthesis of a Conformationally Rigid Calcium Channel Blocker.

    المؤلفون: BARRISH, J. C., SPERGEL, S. H., MORELAND, S., HEDBERG, S. A.

    المصدر: ChemInform ; volume 24, issue 4 ; ISSN 0931-7597 1522-2667

    الاتاحة: http://dx.doi.org/10.1002/chin.199304156
    https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchin.199304156
    https://onlinelibrary.wiley.com/doi/pdf/10.1002/chin.199304156

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  10. 10
    Periodical
    5-Cyanopyrimidine Derivatives as a Novel Class of Potent, Selective, and Orally Active Inhibitors of p38α MAP Kinase

    المؤلفون: Liu, C., Wrobleski, S. T., Lin, J., Ahmed, G., Metzger, A., Wityak, J., Gillooly, K. M., Shuster, D. J., McIntyre, K. W., Pitt, S., Shen, D. R., Zhang, R. F., Zhang, H., Doweyko, A. M., Diller, D., Henderson, I., Barrish, J. C., Dodd, J. H., Schieven, G. L., Leftheris, K.

    المصدر: Journal of Medicinal Chemistry; October 2005, Vol. 48 Issue: 20 p6261-6270, 10p


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  11. 11
    Periodical
    Design, Synthesis, and Evaluation of Orally Active 4-(2,4-Difluoro-5-(methoxycarbamoyl)phenylamino)pyrrolo[2,1-f][1,2,4]triazines as Dual Vascular Endothelial Growth Factor Receptor-2 and Fibroblast Growth Factor Receptor-1 Inhibitors

    المؤلفون: Borzilleri, R. M., Zheng, X., Qian, L., Ellis, C., Cai, Z.-w., Wautlet, B. S., Mortillo, S., Jeyaseelan, R., Sr., Kukral, D. W., Fura, A., Kamath, A., Vyas, V., Tokarski, J. S., Barrish, J. C., Hunt, J. T., Lombardo, L. J., Fargnoli, J., Bhide, R. S.

    المصدر: Journal of Medicinal Chemistry; June 2005, Vol. 48 Issue: 12 p3991-4008, 18p


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  12. 12
    Periodical
    Discovery of N-(2-Chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a Dual Src/Abl Kinase Inhibitor with Potent Antitumor Activity in Preclinical Assays

    المؤلفون: Lombardo, L. J., Lee, F. Y., Chen, P., Norris, D., Barrish, J. C., Behnia, K., Castaneda, S., Cornelius, L. A. M., Das, J., Doweyko, A. M., Fairchild, C., Hunt, J. T., Inigo, I., Johnston, K., Kamath, A., Kan, D., Klei, H., Marathe, P., Pang, S., Peterson, R., Pitt, S., Schieven, G. L., Schmidt, R. J., Tokarski, J., Wen, M.-L., Wityak, J., Borzilleri, R. M.

    المصدر: Journal of Medicinal Chemistry; December 2004, Vol. 47 Issue: 27 p6658-6661, 4p


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  13. 13
    Periodical
    Imidazoquinoxaline Src-Family Kinase p56Lck Inhibitors:  SAR, QSAR, and the Discovery of (S)-N-(2-Chloro-6-methylphenyl)-2-(3-methyl-1-piperazinyl)imidazo- [1,5-a]pyrido[3,2-e]pyrazin-6-amine (BMS-279700) as a Potent and Orally Active Inhibitor with Excellent in Vivo Antiinflammatory Activity

    المؤلفون: Chen, P., Doweyko, A. M., Norris, D., Gu, H. H., Spergel, S. H., Das, J., Moquin, R. V., Lin, J., Wityak, J., Iwanowicz, E. J., McIntyre, K. W., Shuster, D. J., Behnia, K., Chong, S., Fex, H. de, Pang, S., Pitt, S., Shen, D. R., Thrall, S., Stanley, P., Kocy, O. R., Witmer, M. R., Kanner, S. B., Schieven, G. L., Barrish, J. C.

    المصدر: Journal of Medicinal Chemistry; August 2004, Vol. 47 Issue: 18 p4517-4529, 13p


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  14. 14
    Periodical
    Biphenylsulfonamide Endothelin Receptor Antagonists. 4. Discovery of N-[[2‘-[[(4,5-Dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1‘-biphenyl]- 2-yl]methyl]-N,3,3-trimethylbutanamide (BMS-207940), A Highly Potent and Orally Active ETA Selective Antagonist

    المؤلفون: Murugesan, N., Gu, Z., Spergel, S., Young, M., Chen, P., Mathur, A., Leith, L., Hermsmeier, M., Liu, E. C.-K., Zhang, R., Bird, E., Waldron, T., Marino, A., Koplowitz, B., Humphreys, W. G., Chong, S., Morrison, R. A., Webb, M. L., Moreland, S., Trippodo, N., Barrish, J. C.

    المصدر: Journal of Medicinal Chemistry; January 2003, Vol. 46 Issue: 1 p125-137, 13p


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  15. 15
    Periodical
    Discovery of N-Isoxazolyl Biphenylsulfonamides as Potent Dual Angiotensin II and Endothelin A Receptor Antagonists

    المؤلفون: Murugesan, N., Tellew, J. E., Gu, Z., Kunst, B. L., Fadnis, L., Cornelius, L. A., Baska, R. A. F., Yang, Y., Beyer, S. M., Monshizadegan, H., Dickinson, K. E., Panchal, B., Valentine, M. T., Chong, S., Morrison, R. A., Carlson, K. E., Powell, J. R., Moreland, S., Barrish, J. C., Kowala, M. C., Macor, J. E.

    المصدر: Journal of Medicinal Chemistry; August 2002, Vol. 45 Issue: 18 p3829-3835, 7p


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  16. 16
    Periodical
    Discovery of N-[2-[2-[[3-Methoxy-4-(5-oxazolyl)phenyl]amino]-5-oxazolyl]phenyl]-N-methyl-4- morpholineacetamide as a Novel and Potent Inhibitor of Inosine Monophosphate Dehydrogenase with Excellent in Vivo Activity

    المؤلفون: Dhar, T. G. M., Shen, Z., Guo, J., Liu, C., Watterson, S. H., Gu, H. H., Pitts, W. J., Fleener, C. A., Rouleau, K. A., Sherbina, N. Z., McIntyre, K. W., Witmer, M. R., Tredup, J. A., Chen, B.-C., Zhao, R., Bednarz, M. S., Cheney, D. L., MacMaster, J. F., Miller, L. M., Berry, K. K., Harper, T. W., Barrish, J. C., Hollenbaugh, D. L., Iwanowicz, E. J.

    المصدر: Journal of Medicinal Chemistry; May 2002, Vol. 45 Issue: 11 p2127-2130, 4p


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  17. 17
    Periodical
    Biphenylsulfonamide Endothelin Receptor Antagonists. Part 3: Structure-Activity Relationship of 4prime-Heterocyclic Biphenylsulfonamides

    المؤلفون: Murugesan, N., Gu, Z., Stein, P. D., Spergel, S., Bisaha, S., Liu, E. C., Zhang, R., Webb, M. L., Moreland, S., Barrish, J. C.

    المصدر: Bioorganic & Medicinal Chemistry Letters; 2002, Vol. 12 Issue: 4 p517-520, 4p


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  18. 18
    Periodical
    Biphenylsulfonamide Endothelin Receptor Antagonists. 2. Discovery of 4‘-Oxazolyl Biphenylsulfonamides as a New Class of Potent, Highly Selective ETA Antagonists

    المؤلفون: Murugesan, N., Gu, Z., Stein, P. D., Spergel, S., Mathur, A., Leith, L., Liu, E. C.-K., Zhang, R., Bird, E., Waldron, T., Marino, A., Morrison, R. A., Webb, M. L., Moreland, S., Barrish, J. C.

    المصدر: Journal of Medicinal Chemistry; August 10, 2000, Vol. 43 Issue: 16 p3111-3117, 7p


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  19. 19
    Periodical
    Solid phase synthesis of phosphinic acid endothelin converting enzyme inhibitors

    المؤلفون: Lloyd, J., Schmidt, J. B., Hunt, J. T., Barrish, J. C., Little, D. K., Tymiak, A. A.

    المصدر: Bioorganic & Medicinal Chemistry Letters; 1996, Vol. 6 Issue: 12 p1323-1326, 4p


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  20. 20
    Periodical
    Aminodiol HIV Protease Inhibitors. Synthesis And Structure−Activity Relationships Of P1/P1‘ Compounds:  Correlation between Lipophilicity and Cytotoxicity

    المؤلفون: Chen, P., Cheng, P. T. W., Alam, M., Beyer, B. D., Bisacchi, G. S., Dejneka, T., Evans, A. J., Greytok, J. A., Hermsmeier, M. A., Humphreys, W. G., Jacobs, G. A., Kocy, O., Lin, P.-F., Lis, K. A., Marella, M. A., Ryono, D. E., Sheaffer, A. K., Spergel, S. H., Sun, C.-q., Tino, J. A., Vite, G., Colonno, R. J., Zahler, R., Barrish, J. C.

    المصدر: Journal of Medicinal Chemistry; May 10, 1996, Vol. 39 Issue: 10 p1991-2007, 17p


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