يعرض 1 - 18 نتائج من 18 نتيجة بحث عن '"Aysel Ahadova (9668819)"', وقت الاستعلام: 0.40s تنقيح النتائج
  1. 1
    Table_1_Beta-2-microglobulin Mutations Are Linked to a Distinct Metastatic Pattern and a Favorable Outcome in Microsatellite-Unstable Stage IV Gastrointestinal Cancers.docx

    المؤلفون: Elena Busch (8089922), Aysel Ahadova (9668819), Kosima Kosmalla (10939305), Lena Bohaumilitzky (10939308), Pauline L. Pfuderer (10939311), Alexej Ballhausen (10939314), Johannes Witt (150415), Jan-Niklas Wittemann (10939317), Hendrik Bläker (714011), Elke Holinski-Feder (9479), Dirk Jäger (11106), Magnus von Knebel Doeberitz (206637), Georg Martin Haag (10939320), Matthias Kloor (218741)

    مصطلحات موضوعية: Cancer, Cancer Cell Biology, Cancer Diagnosis, Cancer Genetics, Cancer Therapy (excl. Chemotherapy and Radiation Therapy), Chemotherapy, Haematological Tumours, Molecular Targets, Radiation Therapy, Solid Tumours, Oncology and Carcinogenesis not elsewhere classified, MSI cancer, metastatic pattern, immune checkpoint blockade, B2M mutation, prognosis, therapy response

    Relation: https://figshare.com/articles/dataset/Table_1_Beta-2-microglobulin_Mutations_Are_Linked_to_a_Distinct_Metastatic_Pattern_and_a_Favorable_Outcome_in_Microsatellite-Unstable_Stage_IV_Gastrointestinal_Cancers_docx/14747649

    الاتاحة: https://doi.org/10.3389/fonc.2021.669774.s001

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  2. 2
    Mathematical background.

    المؤلفون: Saskia Haupt (10819045), Alexander Zeilmann (10819048), Aysel Ahadova (9668819), Hendrik Bläker (714011), Magnus von Knebel Doeberitz (206637), Matthias Kloor (218741), Vincent Heuveline (1535971)

    مصطلحات موضوعية: Medicine, Genetics, Evolutionary Biology, Cancer, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Information Systems not elsewhere classified, gene mutation graphs, DNA mismatch repair, Kronecker structure, driver mutations, Cartesian graph product, KRAS, CRC, LS-associated colorectal carcinogenesis, TP, pathway, point mutation rates, MMR-proficient APC-inactivated crypts, colorectal carcinogenesis, driver gene mutation graphs, CTNNB 1 mutations

    Relation: https://figshare.com/articles/dataset/Mathematical_background_/14613580

    الاتاحة: https://doi.org/10.1371/journal.pcbi.1008970.s001

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  3. 3
    Image
    Gene mutation graphs.

    المؤلفون: Saskia Haupt (10819045), Alexander Zeilmann (10819048), Aysel Ahadova (9668819), Hendrik Bläker (714011), Magnus von Knebel Doeberitz (206637), Matthias Kloor (218741), Vincent Heuveline (1535971)

    مصطلحات موضوعية: Medicine, Genetics, Evolutionary Biology, Cancer, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Information Systems not elsewhere classified, gene mutation graphs, DNA mismatch repair, Kronecker structure, driver mutations, Cartesian graph product, KRAS, CRC, LS-associated colorectal carcinogenesis, TP, pathway, point mutation rates, MMR-proficient APC-inactivated crypts, colorectal carcinogenesis, driver gene mutation graphs, CTNNB 1 mutations

    Relation: https://figshare.com/articles/figure/Gene_mutation_graphs_/14613586

    الاتاحة: https://doi.org/10.1371/journal.pcbi.1008970.g002

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  4. 4
    Image
    From the medical hypothesis over the modeling approach to the mathematical structure.

    المؤلفون: Saskia Haupt (10819045), Alexander Zeilmann (10819048), Aysel Ahadova (9668819), Hendrik Bläker (714011), Magnus von Knebel Doeberitz (206637), Matthias Kloor (218741), Vincent Heuveline (1535971)

    مصطلحات موضوعية: Medicine, Genetics, Evolutionary Biology, Cancer, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Information Systems not elsewhere classified, gene mutation graphs, DNA mismatch repair, Kronecker structure, driver mutations, Cartesian graph product, KRAS, CRC, LS-associated colorectal carcinogenesis, TP, pathway, point mutation rates, MMR-proficient APC-inactivated crypts, colorectal carcinogenesis, driver gene mutation graphs, CTNNB 1 mutations

    Relation: https://figshare.com/articles/figure/From_the_medical_hypothesis_over_the_modeling_approach_to_the_mathematical_structure_/14613583

    الاتاحة: https://doi.org/10.1371/journal.pcbi.1008970.g001

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  5. 5
    Image
    Gene mutation graph of APC for increasing the point mutation rate of APC after MMR deficiency.

    المؤلفون: Saskia Haupt (10819045), Alexander Zeilmann (10819048), Aysel Ahadova (9668819), Hendrik Bläker (714011), Magnus von Knebel Doeberitz (206637), Matthias Kloor (218741), Vincent Heuveline (1535971)

    مصطلحات موضوعية: Medicine, Genetics, Evolutionary Biology, Cancer, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Information Systems not elsewhere classified, gene mutation graphs, DNA mismatch repair, Kronecker structure, driver mutations, Cartesian graph product, KRAS, CRC, LS-associated colorectal carcinogenesis, TP, pathway, point mutation rates, MMR-proficient APC-inactivated crypts, colorectal carcinogenesis, driver gene mutation graphs, CTNNB 1 mutations

    Relation: https://figshare.com/articles/figure/Gene_mutation_graph_of_i_APC_i_for_increasing_the_point_mutation_rate_of_i_APC_i_after_MMR_deficiency_/14613592

    الاتاحة: https://doi.org/10.1371/journal.pcbi.1008970.g004

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  6. 6
    Image
    Sparse matrix structure.

    المؤلفون: Saskia Haupt (10819045), Alexander Zeilmann (10819048), Aysel Ahadova (9668819), Hendrik Bläker (714011), Magnus von Knebel Doeberitz (206637), Matthias Kloor (218741), Vincent Heuveline (1535971)

    مصطلحات موضوعية: Medicine, Genetics, Evolutionary Biology, Cancer, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Information Systems not elsewhere classified, gene mutation graphs, DNA mismatch repair, Kronecker structure, driver mutations, Cartesian graph product, KRAS, CRC, LS-associated colorectal carcinogenesis, TP, pathway, point mutation rates, MMR-proficient APC-inactivated crypts, colorectal carcinogenesis, driver gene mutation graphs, CTNNB 1 mutations

    Relation: https://figshare.com/articles/figure/Sparse_matrix_structure_/14613589

    الاتاحة: https://doi.org/10.1371/journal.pcbi.1008970.g003

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  7. 7
    Image
    Model Component for the positive Association of MLH1 and CTNNB1 .

    المؤلفون: Saskia Haupt (10819045), Alexander Zeilmann (10819048), Aysel Ahadova (9668819), Hendrik Bläker (714011), Magnus von Knebel Doeberitz (206637), Matthias Kloor (218741), Vincent Heuveline (1535971)

    مصطلحات موضوعية: Medicine, Genetics, Evolutionary Biology, Cancer, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Information Systems not elsewhere classified, gene mutation graphs, DNA mismatch repair, Kronecker structure, driver mutations, Cartesian graph product, KRAS, CRC, LS-associated colorectal carcinogenesis, TP, pathway, point mutation rates, MMR-proficient APC-inactivated crypts, colorectal carcinogenesis, driver gene mutation graphs, CTNNB 1 mutations

    Relation: https://figshare.com/articles/figure/Model_Component_for_the_positive_Association_of_i_MLH1_i_and_i_CTNNB1_i_/14613595

    الاتاحة: https://doi.org/10.1371/journal.pcbi.1008970.g005

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  8. 8
    Image
    Model Component for Increasing the LOH Rate of MMR, CTNNB1 and TP53 by a Factor δ + 1 after APC Inactivation.

    المؤلفون: Saskia Haupt (10819045), Alexander Zeilmann (10819048), Aysel Ahadova (9668819), Hendrik Bläker (714011), Magnus von Knebel Doeberitz (206637), Matthias Kloor (218741), Vincent Heuveline (1535971)

    مصطلحات موضوعية: Medicine, Genetics, Evolutionary Biology, Cancer, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Information Systems not elsewhere classified, gene mutation graphs, DNA mismatch repair, Kronecker structure, driver mutations, Cartesian graph product, KRAS, CRC, LS-associated colorectal carcinogenesis, TP, pathway, point mutation rates, MMR-proficient APC-inactivated crypts, colorectal carcinogenesis, driver gene mutation graphs, CTNNB 1 mutations

    Relation: https://figshare.com/articles/figure/Model_Component_for_Increasing_the_LOH_Rate_of_MMR_i_CTNNB1_i_and_i_TP53_i_by_a_Factor_i_i_1_after_i_APC_i_Inactivation_/14613598

    الاتاحة: https://doi.org/10.1371/journal.pcbi.1008970.g006

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  9. 9
    Image
    Number of crypts over time in a typical MLH1 Carrier in combined States, like early adenomatous, advanced adenomatous and cancerous states as defined in the text for the given parameter set.

    المؤلفون: Saskia Haupt (10819045), Alexander Zeilmann (10819048), Aysel Ahadova (9668819), Hendrik Bläker (714011), Magnus von Knebel Doeberitz (206637), Matthias Kloor (218741), Vincent Heuveline (1535971)

    مصطلحات موضوعية: Medicine, Genetics, Evolutionary Biology, Cancer, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Information Systems not elsewhere classified, gene mutation graphs, DNA mismatch repair, Kronecker structure, driver mutations, Cartesian graph product, KRAS, CRC, LS-associated colorectal carcinogenesis, TP, pathway, point mutation rates, MMR-proficient APC-inactivated crypts, colorectal carcinogenesis, driver gene mutation graphs, CTNNB 1 mutations

    Relation: https://figshare.com/articles/figure/Number_of_crypts_over_time_in_a_typical_i_MLH1_i_Carrier_in_combined_States_like_early_adenomatous_advanced_adenomatous_and_cancerous_states_as_defined_in_the_text_for_the_given_parameter_set_/14613610

    الاتاحة: https://doi.org/10.1371/journal.pcbi.1008970.g010

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  10. 10
    Parameter setting for the shown Results.

    المؤلفون: Saskia Haupt (10819045), Alexander Zeilmann (10819048), Aysel Ahadova (9668819), Hendrik Bläker (714011), Magnus von Knebel Doeberitz (206637), Matthias Kloor (218741), Vincent Heuveline (1535971)

    مصطلحات موضوعية: Medicine, Genetics, Evolutionary Biology, Cancer, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Information Systems not elsewhere classified, gene mutation graphs, DNA mismatch repair, Kronecker structure, driver mutations, Cartesian graph product, KRAS, CRC, LS-associated colorectal carcinogenesis, TP, pathway, point mutation rates, MMR-proficient APC-inactivated crypts, colorectal carcinogenesis, driver gene mutation graphs, CTNNB 1 mutations

    Relation: https://figshare.com/articles/dataset/Parameter_setting_for_the_shown_Results_/14613628

    الاتاحة: https://doi.org/10.1371/journal.pcbi.1008970.t003

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  11. 11
    Image
    Comparison of APC -/- Crypts in the sporadic Case and in FAP Individuals, where we changed the initial value of the dynamical system as well as n hs ( APC ) = 600 for FAP.

    المؤلفون: Saskia Haupt (10819045), Alexander Zeilmann (10819048), Aysel Ahadova (9668819), Hendrik Bläker (714011), Magnus von Knebel Doeberitz (206637), Matthias Kloor (218741), Vincent Heuveline (1535971)

    مصطلحات موضوعية: Medicine, Genetics, Evolutionary Biology, Cancer, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Information Systems not elsewhere classified, gene mutation graphs, DNA mismatch repair, Kronecker structure, driver mutations, Cartesian graph product, KRAS, CRC, LS-associated colorectal carcinogenesis, TP, pathway, point mutation rates, MMR-proficient APC-inactivated crypts, colorectal carcinogenesis, driver gene mutation graphs, CTNNB 1 mutations

    Relation: https://figshare.com/articles/figure/Comparison_of_i_APC_i_-_-_Crypts_in_the_sporadic_Case_and_in_FAP_Individuals_where_we_changed_the_initial_value_of_the_dynamical_system_as_well_as_i_n_i_sub_hs_sub_i_APC_i_600_for_FAP_/14613619

    الاتاحة: https://doi.org/10.1371/journal.pcbi.1008970.g013

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  12. 12
    Estimates for n hs .

    المؤلفون: Saskia Haupt (10819045), Alexander Zeilmann (10819048), Aysel Ahadova (9668819), Hendrik Bläker (714011), Magnus von Knebel Doeberitz (206637), Matthias Kloor (218741), Vincent Heuveline (1535971)

    مصطلحات موضوعية: Medicine, Genetics, Evolutionary Biology, Cancer, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Information Systems not elsewhere classified, gene mutation graphs, DNA mismatch repair, Kronecker structure, driver mutations, Cartesian graph product, KRAS, CRC, LS-associated colorectal carcinogenesis, TP, pathway, point mutation rates, MMR-proficient APC-inactivated crypts, colorectal carcinogenesis, driver gene mutation graphs, CTNNB 1 mutations

    Relation: https://figshare.com/articles/dataset/Estimates_for_i_n_i_sub_hs_sub_/14613622

    الاتاحة: https://doi.org/10.1371/journal.pcbi.1008970.t001

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  13. 13
    Image
    Number of MMR-deficient crypts over the life of a typical lynch syndrome patient for MLH1 and MSH2 .

    المؤلفون: Saskia Haupt (10819045), Alexander Zeilmann (10819048), Aysel Ahadova (9668819), Hendrik Bläker (714011), Magnus von Knebel Doeberitz (206637), Matthias Kloor (218741), Vincent Heuveline (1535971)

    مصطلحات موضوعية: Medicine, Genetics, Evolutionary Biology, Cancer, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Information Systems not elsewhere classified, gene mutation graphs, DNA mismatch repair, Kronecker structure, driver mutations, Cartesian graph product, KRAS, CRC, LS-associated colorectal carcinogenesis, TP, pathway, point mutation rates, MMR-proficient APC-inactivated crypts, colorectal carcinogenesis, driver gene mutation graphs, CTNNB 1 mutations

    Relation: https://figshare.com/articles/figure/Number_of_MMR-deficient_crypts_over_the_life_of_a_typical_lynch_syndrome_patient_for_i_MLH1_i_and_i_MSH2_i_/14613607

    الاتاحة: https://doi.org/10.1371/journal.pcbi.1008970.g009

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  14. 14
    Image
    Model component for increasing the mutation rate of KRAS after MMR deficiency.

    المؤلفون: Saskia Haupt (10819045), Alexander Zeilmann (10819048), Aysel Ahadova (9668819), Hendrik Bläker (714011), Magnus von Knebel Doeberitz (206637), Matthias Kloor (218741), Vincent Heuveline (1535971)

    مصطلحات موضوعية: Medicine, Genetics, Evolutionary Biology, Cancer, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Information Systems not elsewhere classified, gene mutation graphs, DNA mismatch repair, Kronecker structure, driver mutations, Cartesian graph product, KRAS, CRC, LS-associated colorectal carcinogenesis, TP, pathway, point mutation rates, MMR-proficient APC-inactivated crypts, colorectal carcinogenesis, driver gene mutation graphs, CTNNB 1 mutations

    Relation: https://figshare.com/articles/figure/Model_component_for_increasing_the_mutation_rate_of_i_KRAS_i_after_MMR_deficiency_/14613604

    الاتاحة: https://doi.org/10.1371/journal.pcbi.1008970.g008

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  15. 15
    Image
    Model component for the mutual Enhancement of two dependencies by a factor δr effLOH .

    المؤلفون: Saskia Haupt (10819045), Alexander Zeilmann (10819048), Aysel Ahadova (9668819), Hendrik Bläker (714011), Magnus von Knebel Doeberitz (206637), Matthias Kloor (218741), Vincent Heuveline (1535971)

    مصطلحات موضوعية: Medicine, Genetics, Evolutionary Biology, Cancer, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Information Systems not elsewhere classified, gene mutation graphs, DNA mismatch repair, Kronecker structure, driver mutations, Cartesian graph product, KRAS, CRC, LS-associated colorectal carcinogenesis, TP, pathway, point mutation rates, MMR-proficient APC-inactivated crypts, colorectal carcinogenesis, driver gene mutation graphs, CTNNB 1 mutations

    Relation: https://figshare.com/articles/figure/Model_component_for_the_mutual_Enhancement_of_two_dependencies_by_a_factor_i_r_i_sub_effLOH_sub_/14613601

    الاتاحة: https://doi.org/10.1371/journal.pcbi.1008970.g007

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  16. 16
    Image
    Comparison of MMR-deficient Crypts in Lynch-like and Lynch syndrome individuals.

    المؤلفون: Saskia Haupt (10819045), Alexander Zeilmann (10819048), Aysel Ahadova (9668819), Hendrik Bläker (714011), Magnus von Knebel Doeberitz (206637), Matthias Kloor (218741), Vincent Heuveline (1535971)

    مصطلحات موضوعية: Medicine, Genetics, Evolutionary Biology, Cancer, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Information Systems not elsewhere classified, gene mutation graphs, DNA mismatch repair, Kronecker structure, driver mutations, Cartesian graph product, KRAS, CRC, LS-associated colorectal carcinogenesis, TP, pathway, point mutation rates, MMR-proficient APC-inactivated crypts, colorectal carcinogenesis, driver gene mutation graphs, CTNNB 1 mutations

    Relation: https://figshare.com/articles/figure/Comparison_of_MMR-deficient_Crypts_in_Lynch-like_and_Lynch_syndrome_individuals_/14613616

    الاتاحة: https://doi.org/10.1371/journal.pcbi.1008970.g012

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  17. 17
    Image
    Proportion of MMR-proficient and MMR-deficient crypts in a typical MLH1 carrier in different States corresponding to the states in the classical adenoma-carcinoma sequence by Vogelstein [7].

    المؤلفون: Saskia Haupt (10819045), Alexander Zeilmann (10819048), Aysel Ahadova (9668819), Hendrik Bläker (714011), Magnus von Knebel Doeberitz (206637), Matthias Kloor (218741), Vincent Heuveline (1535971)

    مصطلحات موضوعية: Medicine, Genetics, Evolutionary Biology, Cancer, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Information Systems not elsewhere classified, gene mutation graphs, DNA mismatch repair, Kronecker structure, driver mutations, Cartesian graph product, KRAS, CRC, LS-associated colorectal carcinogenesis, TP, pathway, point mutation rates, MMR-proficient APC-inactivated crypts, colorectal carcinogenesis, driver gene mutation graphs, CTNNB 1 mutations

    Relation: https://figshare.com/articles/figure/Proportion_of_MMR-proficient_and_MMR-deficient_crypts_in_a_typical_i_MLH1_i_carrier_in_different_States_corresponding_to_the_states_in_the_classical_adenoma-carcinoma_sequence_by_Vogelstein_7_/14613613

    الاتاحة: https://doi.org/10.1371/journal.pcbi.1008970.g011

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  18. 18
    Estimates for n bp .

    المؤلفون: Saskia Haupt (10819045), Alexander Zeilmann (10819048), Aysel Ahadova (9668819), Hendrik Bläker (714011), Magnus von Knebel Doeberitz (206637), Matthias Kloor (218741), Vincent Heuveline (1535971)

    مصطلحات موضوعية: Medicine, Genetics, Evolutionary Biology, Cancer, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Information Systems not elsewhere classified, gene mutation graphs, DNA mismatch repair, Kronecker structure, driver mutations, Cartesian graph product, KRAS, CRC, LS-associated colorectal carcinogenesis, TP, pathway, point mutation rates, MMR-proficient APC-inactivated crypts, colorectal carcinogenesis, driver gene mutation graphs, CTNNB 1 mutations

    Relation: https://figshare.com/articles/dataset/Estimates_for_i_n_i_sub_bp_sub_/14613625

    الاتاحة: https://doi.org/10.1371/journal.pcbi.1008970.t002

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