المؤلفون: Godefridus J. Peters, Masakazu Fukushima, Paul P. Eijk, Bauke Ylstra, Richard J. Honeywell, Kees Smid, Auke D. Adema, Nienke Losekoot, Henk-Jan Prins, Irene V. Bijnsdorp, Olaf H. Temmink

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae2bf0ea06ae01c6fec69291c8b070d
https://doi.org/10.1158/1535-7163.c.6531774

المؤلفون: Godefridus J. Peters, Masakazu Fukushima, Paul P. Eijk, Bauke Ylstra, Richard J. Honeywell, Kees Smid, Auke D. Adema, Nienke Losekoot, Henk-Jan Prins, Irene V. Bijnsdorp, Olaf H. Temmink

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c33d9c0373858d6e8a91df2cdb7760b
https://doi.org/10.1158/1535-7163.22485105.v1

المؤلفون: Michiel De Bruin, Godefridus J Peters, Ruud Oerlemans, Yehuda G Assaraf, Allan J Masterson, Auke D Adema, Ben A C Dijkmans, Herbert M Pinedo, Gerrit Jansen, J P, A J M, A D A, H M P, Rheumatology, R O, B A C D, G J ) Vu

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://molpharm.aspetjournals.org/content/molpharm/66/4/1054.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1071.5174; http://molpharm.aspetjournals.org/content/molpharm/66/4/1054.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1071.5174
http://molpharm.aspetjournals.org/content/molpharm/66/4/1054.full.pdf

المؤلفون: Richard J. Honeywell, Godefridus J. Peters, Masakazu Fukushima, Nienke Losekoot, Paul P. Eijk, Kees Smid, Olaf H. Temmink, Auke D. Adema, Irene V. Bijnsdorp, Bauke Ylstra, Henk-Jan Prins

المساهمون: Medical oncology, Urology, Medical oncology laboratory, Pathology, CCA - Immuno-pathogenesis

المصدر: Temmink, O H, Bijnsdorp, I V, Prins, H J, Losekoot, N, Adema, A D, Smid, K, Honeywell, R J, Ylstra, B, Eijk, P P, Fukushima, M & Peters, G J 2010, ' Trifluorothymidine Resistance Is Associated with Decreased Thymidine Kinase and Equilibrative Nucleoside Transporter Expression or Increased Secretory Phospholipase A2 ', Molecular Cancer Therapeutics, vol. 9, no. 4, pp. 1047-1057 . https://doi.org/10.1158/1535-7163.MCT-09-0932
Molecular Cancer Therapeutics, 9(4), 1047-1057. American Association for Cancer Research Inc.

مصطلحات موضوعية: Cancer Research, DNA Copy Number Variations, Down-Regulation, Biology, Thymidylate synthase, Thymidine Kinase, Trifluridine, Cell Line, Tumor, Equilibrative Nucleoside Transport Proteins, Gene expression, Humans, Thymidine phosphorylase, Enzyme Inhibitors, Phospholipases A2, Secretory, Cell Proliferation, Oligonucleotide Array Sequence Analysis, Regulation of gene expression, Comparative Genomic Hybridization, Gene Expression Profiling, Cell Cycle, Equilibrative nucleoside transporter, Thymidylate Synthase, Cell cycle, Lipid Metabolism, Molecular biology, Up-Regulation, Gene Expression Regulation, Neoplastic, Oncology, Cell culture, Thymidine kinase, Drug Resistance, Neoplasm, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa21539dfbee8dc762837370af4b566
https://doi.org/10.1158/1535-7163.mct-09-0932

المؤلفون: RADI, Marco, Auke D. Adema, Jonathan R. Daft, Jong H. Cho, Eveline K. Hoebe, Lou Ella M. M. Alexander, Godefridus J. Peters, Chung K. Chu

المساهمون: Radi, Marco, Auke D., Adema, Jonathan R., Daft, Jong H., Cho, Eveline K., Hoebe, Lou Ella M. M., Alexander, Godefridus J., Peter, Chu, Chung K.

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000245954600028; volume:50; firstpage:2249; lastpage:2253; numberofpages:5; journal:JOURNAL OF MEDICINAL CHEMISTRY; http://hdl.handle.net/11381/2432281; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-34247611805

الاتاحة: http://hdl.handle.net/11381/2432281
https://doi.org/10.1021/jm0612923

المؤلفون: Charlotte M. Huijts, Godefridus J. Peters, Auke D. Adema, Gareth J. Veal, Abolfazl Avan, Amir Avan, Eveline K. Hoebe, Katja Wosikowski, Rob Ruijtenbeek

المساهمون: Medical oncology laboratory, Medical oncology, Pathology, CCA - Innovative therapy, Other departments

المصدر: Current Drug Targets, 15(14), 1312-1321. Bentham Science Publishers B.V.
Scopus-Elsevier
Avan, A, Adema, A D, Hoebe, E K, Huijts, C M, Avan, A, Veal, G J, Ruijtenbeek, R, Wosikowski, K & Peters, G J 2014, ' Modulation of Signaling Enhances the Efficacy of the Combination of Satraplatin and Erlotinib ', Current Drug Targets, vol. 15, no. 14, pp. 1312-1321 . https://doi.org/10.2174/1389450115666141107110321
Current drug targets, 15(14), 1312-1321. Bentham Science Publishers B.V.

مصطلحات موضوعية: MAPK/ERK pathway, Organoplatinum Compounds, Clinical Biochemistry, Antineoplastic Agents, Apoptosis, Satraplatin, Pharmacology, chemistry.chemical_compound, DNA Adducts, Erlotinib Hydrochloride, Cell Line, Tumor, Neoplasms, Drug Discovery, medicine, PTEN, Humans, Epidermal growth factor receptor, Phosphorylation, neoplasms, biology, Cell Cycle, Drug Synergism, Cell cycle, respiratory tract diseases, Gene Expression Regulation, Neoplastic, chemistry, biology.protein, Quinazolines, Molecular Medicine, Drug Therapy, Combination, Erlotinib, medicine.drug, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9875ce76d8337755183a1538773e0843
https://pubmed.ncbi.nlm.nih.gov/25382189

المؤلفون: Marit Liland Sandvold, Auke D. Adema, Godefridus J. Peters, Irene V. Bijnsdorp

المساهمون: Medical oncology laboratory, Medical oncology, Urology, CCA - Innovative therapy

المصدر: Nucleosides, Nucleotides and Nucleic Acids, 30(12), 1168-1180. Taylor and Francis Ltd.
Peters, G J, Adema, A D, Bijnsdorp, I V & Sandvold, ML 2011, ' Lipophilic Prodrugs and Formulations of Conventional (Deoxy) Nucleoside and Fluoropyrimidine Analogs in Cancer ', Nucleosides, Nucleotides and Nucleic Acids, vol. 30, no. 12, pp. 1168-1180 . https://doi.org/10.1080/15257770.2011.607143

مصطلحات موضوعية: Drug, Biodistribution, media_common.quotation_subject, Chemistry, Pharmaceutical, Biochemistry, Neoplasms, Genetics, medicine, Moiety, Humans, Prodrugs, media_common, chemistry.chemical_classification, Liposome, Nucleoside analogue, Nucleosides, General Medicine, Lipids, Enzyme, Pyrimidines, chemistry, Targeted drug delivery, Molecular Medicine, Nucleoside, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc8022f24a56e4f9fdacb90676eee57
https://pubmed.ncbi.nlm.nih.gov/22132972

المؤلفون: Dennis Fontijn, Epie Boven, Herbert M. Pinedo, Kishor K. Bhakat, Auke D. Adema, Godefridus J. Peters

المصدر: Molecular cancer therapeutics. 6(10)

مصطلحات موضوعية: Gene isoform, Cancer Research, Guanine, Skin Neoplasms, Base Pair Mismatch, Basic fibroblast growth factor, Blotting, Western, Clone (cell biology), Antineoplastic Agents, Biology, DNA Mismatch Repair, chemistry.chemical_compound, O(6)-Methylguanine-DNA Methyltransferase, medicine, Temozolomide, Tumor Cells, Cultured, Humans, RNA, Messenger, RNA, Neoplasm, Luciferases, Promoter Regions, Genetic, Antineoplastic Agents, Alkylating, Melanoma, Cisplatin, Reverse Transcriptase Polymerase Chain Reaction, Transfection, DNA Methylation, Molecular biology, Demethylating agent, Blot, Dacarbazine, DNA Repair Enzymes, Oncology, chemistry, Drug Resistance, Neoplasm, DNA methylation, Fibroblast Growth Factor 2, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4698f4a1a75a02a6223e908b29b7468c
https://pubmed.ncbi.nlm.nih.gov/17938272

المؤلفون: Eveline K. Hoebe, Godefridus J. Peters, Auke D. Adema, Chung K. Chu, Lou-Ella M. M. Alexander, Jong H. Cho, Marco Radi, Jonathan R. Daft

المساهمون: Other departments

المصدر: Journal of medicinal chemistry, 50(9), 2249-2253. American Chemical Society

مصطلحات موضوعية: Lung Neoplasms, Troxacitabine, Antineoplastic Agents, Cytosine, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Drug Discovery, medicine, Humans, Prodrugs, Cytotoxicity, Fatty acid amide, Dioxolanes, Stereoisomerism, Cytidine, Prodrug, medicine.disease, In vitro, Leukemia, Biochemistry, chemistry, Cancer research, Molecular Medicine, Drug Screening Assays, Antitumor, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac89060b027bdf1e3f9df988210a8cb2
https://pure.amc.nl/en/publications/in-vitro-optimization-of-nonsmall-cell-lung-cancer-activity-with-troxacitabine-l13dioxolanecytidine-prodrugs(b694a4df-8eb3-46d0-a7c5-7e640d8191ce).html

المؤلفون: Auke D. Adema, Godefridus J. Peters, Ben A. C. Dijkmans, Allan J. Masterson, Ruud Oerlemans, Gerrit Jansen, Michiel de Bruin, Yehuda G. Assaraf, Herbert M. Pinedo

المساهمون: Medical oncology, Pathology, Rheumatology

المصدر: Molecular Pharmacology, 66(4), 1054-60. American Society for Pharmacology and Experimental Therapeutics
de Bruin, M, Peters, G J, Oerlemans, R, Assaraf, Y G, Masterson, A J, Adema, A D, Dijkmans, B A C, Pinedo, H M & Jansen, G 2004, ' Sulfasalazine down-regulates the expression of the angiogenic factors platelet-derived endothelial cell growth factor/thymidine phosphorylase and interleukin-8 in human monocytic-macrophage THP1 and U937 cells ', Molecular Pharmacology, vol. 66, no. 4, pp. 1054-60 . https://doi.org/10.1124/mol.104.000315

مصطلحات موضوعية: medicine.medical_specialty, Tumor Infiltrating Macrophages, Blotting, Western, Gene Expression, Biology, Monocytes, Sulfasalazine, Internal medicine, medicine, Macrophage, Humans, Receptors, Tumor Necrosis Factor, Type II, Interleukin 8, RNA, Messenger, Thymidine phosphorylase, Receptors, Interferon, Pharmacology, Thymidine Phosphorylase, U937 cell, Macrophages, Anti-Inflammatory Agents, Non-Steroidal, Interleukin-8, NF-kappa B, Transcription Factor RelA, NF-kappa B p50 Subunit, U937 Cells, Endocrinology, Receptors, Tumor Necrosis Factor, Type I, Cancer research, Molecular Medicine, Tumor necrosis factor alpha, Angiogenesis Inducing Agents, Signal transduction, medicine.drug, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed9614e49840542759515322793ab22
https://research.vumc.nl/en/publications/16f6b30c-642b-4c1c-a52f-038961251476

المؤلفون: Marco Radi, Auke D. Adema, Jonathan R. Daft, Jong H. Cho, Eveline K. Hoebe, Lou-Ella M. M. Alexander, Godefridus J. Peters, Chung K. Chu

المصدر: Journal of Medicinal Chemistry; May2007, Vol. 50 Issue 9, p2249-2253, 5p