المؤلفون: Sueli Rosa Gama, Letícia de Oliveira Cardoso, Igor Kippe Rubinsztajn, Audrey Fischer, Marilia Sá Carvalho

المصدر: Revista Brasileira de Saúde Materno Infantil, Vol 15, Iss 4, Pp 425-434 (2015)

مصطلحات موضوعية: Economia dos alimentos, Consumo de alimentos, Nutrição da criança, Gynecology and obstetrics, RG1-991

وصف الملف: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292015000400425&lng=en&tlng=en; https://doaj.org/toc/1806-9304

URL الوصول: https://doaj.org/article/2a6202316fff4567a98cd14027bd4379

المؤلفون: Axel T Brunger, Mark A Breidenbach, Rongsheng Jin, Audrey Fischer, Jose S Santos, Mauricio Montal

المصدر: PLoS Pathogens, Vol 3, Iss 9, Pp 1191-1194 (2007)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

URL الوصول: https://doaj.org/article/71bee96a6acf498585c05a2872aac763

المؤلفون: Camila do Espírito Santo Nascimento, Audrey Fischer, Tatiane Santiago Santos, Rosane Melo, Aline Bento da Silva, Amanda Prutchi, Alda Aparecida

المصدر: Revista de Pesquisa : Cuidado é Fundamental Online (2011)

مصطلحات موضوعية: enfermagem psiquiátrica, Medicine, Nursing, RT1-120

وصف الملف: electronic resource

Relation: http://seer.unirio.br/cuidadofundamental/article/view/1192; https://doaj.org/toc/1809-6107; https://doaj.org/toc/2175-5361

URL الوصول: https://doaj.org/article/d21baa292dc547d6a6ba97a024eeed10

المؤلفون: Audrey Fischer, Enirtes Caetano Prates Melo, Elaine da Costa Guimarães

المصدر: Revista de Pesquisa : Cuidado é Fundamental Online (2010)

مصطلحات موضوعية: Enfermagem, Apoio Social, recém-nascido, Medicine, Nursing, RT1-120

وصف الملف: electronic resource

Relation: http://www.seer.unirio.br/cuidadofundamental/article/view/805; https://doaj.org/toc/1809-6107; https://doaj.org/toc/2175-5361

URL الوصول: https://doaj.org/article/d4c2d3b558634fcf94da61a90ca16d9d

المؤلفون: Jie Wang, Gregory Vernier, Audrey Fischer, R John Collier

المصدر: PLoS ONE, Vol 4, Iss 7, p e6280 (2009)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC2706995?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/155069fcd9784fab87d4fdbffb325f85

المؤلفون: Audrey Fischer, Darren J Mushrush, D Borden Lacy, Mauricio Montal

المصدر: PLoS Pathogens, Vol 4, Iss 12, p e1000245 (2008)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC2596314?pdf=render; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

URL الوصول: https://doaj.org/article/dc8dbb1632d54f40a314df57e8c39fe0

المؤلفون: Vlasia Kastrinou, Lampou, Birk, Poller, Felix, Huth, Audrey, Fischer, Gerd A, Kullak-Ublick, Michael, Arand, Heiko S, Schadt, Gian, Camenisch

المساهمون: University of Zurich, Camenisch, Gian

مصطلحات موضوعية: 10199 Clinic for Clinical Pharmacology and Toxicology, 3005 Toxicology, 610 Medicine & health, General Medicine, Toxicology

وصف الملف: 1_s2.0_S0887233322002314_main.pdf - application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90b6f5e9ef839f95ec31f9b1f235731
https://www.zora.uzh.ch/id/eprint/231847/

المؤلفون: Veronica V. Rezelj, Audrey Fischer, Francesca Moretti, Romel Rosales, Olivier Schwartz, Jiankun Lyu, Francois Pognan, Andrew C. Kruse, Kris M. White, Marco Vignuzzi, Heiko Schadt, Ziyang Zhang, Henry R. O’Donnell, Michael Schotsaert, Kevan M. Shokat, Tia A. Tummino, Adolfo García-Sastre, Nevan J. Krogan, Jean-Rene Galarneau, Raveen Rathnasinghe, Blandine Monel, Benoit Fischer, Briana L. McGovern, Assaf Alon, Matthew J. O’Meara, Thomas Vallet, Brian K. Shoichet, Sonia Jangra, Laszlo Urban

المساهمون: University of California [San Francisco] (UC San Francisco), University of California (UC), Populations virales et Pathogenèse - Viral Populations and Pathogenesis, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Novartis Institutes for BioMedical Research (NIBR), University of Michigan [Ann Arbor], University of Michigan System, Virus et Immunité - Virus and immunity (CNRS-UMR3569), Icahn School of Medicine at Mount Sinai [New York] (MSSM), Harvard Medical School [Boston] (HMS), This work was supported by grants from the Defense Advanced Research Projects Agency (HR0011-19-2-0020 to B.K.S., N.J.K., A.G.-S., and K.M.S.), NIGMS R35GM122481 (to B.K.S.), National Institutes of Health (P50AI150476, U19AI135990, U19AI135972, R01AI143292, R01AI120694, P01AI063302, and R01AI122747 to N.J.K.), Excellence in Research Award (ERA) from the Laboratory for Genomics Research (LGR) (to N.J.K.), a collaboration between UCSF, UCB, and GSK (no. 133122P to N.J.K.), a Fast Grant for COVID-19 from the Emergent Ventures program at the Mercatus Center of George Mason University (to N.J.K.), funding from the Roddenberry Foundation (to N.J.K.), funding from F. Hoffmann–La Roche and Vir Biotechnology (to N.J.K.), gifts from QCRG philanthropic donors (to N.J.K.), funding from Institut Pasteur (to O.S. and M.V.), Urgence COVID-19 Fundraising Campaign of Institut Pasteur (to O.S. and M.V.), Labex IBEID (ANR-10-LABX-62-IBEID to O.S. and M.V.), ANR/FRM Flash Covid PROTEO-SARS-CoV-2 (to O.S.), IDISCOVR (to O.S.), National Institutes of Health (R01GM119185 to A.C.K.), partly supported by the Center for Research for Influenza Pathogenesis, a Center of Excellence for Influenza Research and Surveillance supported by the National Institute of Allergy and Infectious Diseases (contract no. HHSN272201400008C to A.G.-S.), a supplement to NIAID grant U19AI135972 and to DoD grant W81XWH-20-1-0270 (to A.G.-S.), a Fast Grant from the Mercatus Center (to A.G.-S.), the generous support of the JPB Foundation and the Open Philanthropy Project [research grant 2020-215611 (5384) to A.G.-S.], and anonymous donors (to A.G.-S.). Z.Z. is a Damon Runyon fellow supported by the Damon Runyon Cancer Research Foundation (DRG-2281-17)., We gratefully acknowledge the Région Ile-de-France (program DIM1Health) for the use of the Institut Pasteur imaging facility. We thank N. Aulner for assistance with image requisition and A. Danckaert for assistance with image analysis at Institut Pasteur, Paris. We thank R. Albrecht for support with the BSL3 facility and procedures at the Icahn School of Medicine at Mount Sinai, New York. We thank C. Hayden for the work with the transmission electron microscopy at Novartis. We thank T. R. O’Meara for reading the manuscript. We thank K. Obernier, M. Bouhaddou, and J. M. Fabius for contributions to the overall COVID-19 effort at QCRG., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), ANR-20-COVI-0059,PROTEO-SARS-CoV-2,Protéomique du SARS-CoV-2(2020)

المصدر: Science (New York, N.Y.)
Science (New York, N.Y.), vol 373, iss 6554
Science
Science, 2021, 373 (6554), pp.541-547. ⟨10.1126/science.abi4708⟩

مصطلحات موضوعية: Drug, General Science & Technology, media_common.quotation_subject, Microbial Sensitivity Tests, Pharmacology, Lipidoses, Virus Replication, Amiodarone, Antiviral Agents, Article, Dose-Response Relationship, Mice, Surface-Active Agents, Cations, Chlorocebus aethiops, Animals, Humans, Medicine, Lung, Vero Cells, Phospholipids, Repurposing, media_common, Phospholipidosis, Multidisciplinary, Dose-Response Relationship, Drug, SARS-CoV-2, Drug discovery, business.industry, Drug Repositioning, COVID-19, Hydroxychloroquine, Molecular Pharmacology, COVID-19 Drug Treatment, Drug repositioning, Infectious Diseases, Good Health and Well Being, 5.1 Pharmaceuticals, A549 Cells, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Female, Development of treatments and therapeutic interventions, business, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e82c7138db547cd2c3c9cdbd9634a67d
https://doi.org/10.1126/science.abi4708

المؤلفون: Enrica Saponara, Carlos Penno, Vanessa Orsini, Zhong-Yi Wang, Audrey Fischer, Alexandra Aebi, Meztli L. Matadamas-Guzman, Virginie Brun, Benoit Fischer, Margaret Brousseau, Peter O'Donnell, Jonathan Turner, Alexandra Graff Meyer, Laura Bollepalli, Giovanni d’Ario, Guglielmo Roma, Walter Carbone, Stefano Annunziato, Michael Obrecht, Nicolau Beckmann, Chandra Saravanan, Arnaud Osmont, Philipp Tropberger, Shola M. Richards, Christel Genoud, Svenja Ley, Iwona Ksiazek, Florian Nigsch, Luigi M. Terracciano, Heiko S. Schadt, Tewis Bouwmeester, Jan S. Tchorz, Heinz Ruffner

المصدر: The American journal of pathology.

مصطلحات موضوعية: Pathology and Forensic Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7c1c4c6570641d2e5408b53b241d56
https://pubmed.ncbi.nlm.nih.gov/36410420

المؤلفون: Francois Pognan, Laszlo Urban, Heiko Schadt, Veronica V. Rezelj, Adolfo Garcia-Sastre, Olivier Schwartz, Blandine Monel, Nevan J. Krogan, Audrey Fischer, Ziyang Zhang, Brian K. Shoichet, Assaf Alon, Matthew J. O’Meara, Benoit Fischer, Kevan M. Shokat, Tia A. Tummino, Kris M. White, Marco Vignuzzi, Francesca Moretti, Jiankun Lyu, Thomas Vallet, Henry R. O’Donnell, Andrew C. Kruse

المصدر: bioRxiv
article-version (status) pre
article-version (number) 1

مصطلحات موضوعية: Phospholipidosis, Coronavirus disease 2019 (COVID-19), Drug discovery, business.industry, Mechanism (biology), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Medicine, Drug side effects, Pharmacology, business, Article, Repurposing, In vitro

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9022a1070b6eea488945070d6619e143
https://doi.org/10.1101/2021.03.23.436648

المؤلفون: Thomas J. Smith, Peter Thielen, Naiwen Cui, Adrian W.R. Serohijos, Nicholas S. Giacobbi, James M. Pipas, Jeffrey S. Lin, Susan Wu, Jeong-Mo Choi, Thomas Mehoke, Hua Zhang, David A. Weitz, Lloyd W. Ung, Ye Tao, Audrey Fischer, João V. Rodrigues, Joshua T. Wolfe, Andrew B. Feldman, Eugene I. Shakhnovich, Abimbola O. Kolawole, Connie B. Chang, Stephan A. Koehler, Plamen A. Demirev, Kellogg J. Schwab, Timothy R. Julian, Assaf Rotem, Christiane E. Wobus

المصدر: Molecular Biology and Evolution

مصطلحات موضوعية: 0301 basic medicine, Protein Folding, fitness landscape, Fitness landscape, viruses, Genetic Fitness, Antibody Affinity, microfluidics, Biology, 03 medical and health sciences, Mice, viral evolution, Genetics, Animals, Selection, Genetic, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Selection (genetic algorithm), Discoveries, lab evolution, Experimental evolution, Models, Genetic, Protein Stability, Fitness model, Norovirus, neutralizing antibody, Epistasis, Genetic, folding stability, Antibodies, Neutralizing, Biological Evolution, Folding (chemistry), 030104 developmental biology, Evolutionary biology, Viral evolution, Epistasis, Capsid Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0f479e2ee679ad27ce0dc79d5630c0
https://pubmed.ncbi.nlm.nih.gov/29955873

المؤلفون: Marc A. Wolman, Michael Granato, Audrey Fischer, Emily English, Andrew S. McCallion, Jody B. G. Proescher, Michael J. Parsons

المصدر: Neurotoxicology and Teratology. 50:1-10

مصطلحات موضوعية: Embryo, Nonmammalian, Neurite, Neurogenesis, Physostigmine, Pharmacology, Toxicology, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Developmental Neuroscience, medicine, Animals, Zebrafish, Nerve agent, Dose-Response Relationship, Drug, biology, Organophosphate, medicine.disease, biology.organism_classification, Acetylcholinesterase, Neostigmine, Myasthenia gravis, Disease Models, Animal, Nicotinic agonist, chemistry, Pyridostigmine Bromide, Carbamates, Cholinesterase Inhibitors, Nerve Agents, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d8b4c9a38d7e766cfeaa18350f9b1d
https://doi.org/10.1016/j.ntt.2015.05.001

المؤلفون: Terrilyn A. Richardson, Chi-Hse Teng, Audrey Fischer, Marianne Schwald, William Kluwe, Joerg Andreas Mahl, Robin Alec Fairhurst, Luigi Manenti, Francois Pognan, Armin Wolf, Gerd A. Kullak-Ublick, Mathilde Lienard, Jacqueline Kinyamu-Akunda, Elizabeth Skuba, Salah-Dine Chibout, Andreas Weiss, Kuno Wuersch, Philippe Couttet, Heiko Schadt, Diana Graus Porta, Corinne Emotte

المساهمون: University of Zurich, Kinyamu-Akunda, Jacqueline

المصدر: Toxicological sciences : an official journal of the Society of Toxicology. 163(1)

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, medicine.drug_class, Pyridines, Cholestyramine Resin, 610 Medicine & health, Toxicology, Cholesterol 7 alpha-hydroxylase, Piperazines, Bile Acids and Salts, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Dogs, Internal medicine, Toxicity Tests, medicine, Animals, Receptor, Fibroblast Growth Factor, Type 4, Protein Kinase Inhibitors, Cholestyramine, biology, Bile acid, Dose-Response Relationship, Drug, 3005 Toxicology, FGF19, Alanine Transaminase, Toxicokinetics, Dose–response relationship, 030104 developmental biology, Endocrinology, Alanine transaminase, chemistry, Liver, 10199 Clinic for Clinical Pharmacology and Toxicology, 030220 oncology & carcinogenesis, biology.protein, Female, Taurolithocholic acid, Taurodeoxycholic acid, medicine.drug

وصف الملف: Cholestyramine in dogs paper_v8_Nov22_gku.pdf - application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d746446e070550903c7f77a79f7ce1e
https://pubmed.ncbi.nlm.nih.gov/29432567

المؤلفون: Lloyd W. Ung, Ye Tao, Susan Wu, David A. Weitz, Eugene I. Shakhnovich, Assaf Rotem, Plamen A. Demirev, Thomas J. Smith, Thomas Mehoke, Jeffrey S. Lin, Stephan A. Koehler, Christiane E. Wobus, Naiwen Cui, Adrian W.R. Serohijos, Nicholas S. Giacobbi, Kellogg J. Schwab, Audrey Fischer, Joshua T. Wolfe, Abimbola O. Kolawole, Timothy R. Julian, James M. Pipas, Andrew B. Feldman, Peter Thielen, Connie B. Chang, Hua Zhang, Jeong-Mo Choi

مصطلحات موضوعية: Genetics, 0303 health sciences, Neutral network, Experimental evolution, Fitness landscape, viruses, Fitness model, 030302 biochemistry & molecular biology, Biology, 3. Good health, Folding (chemistry), 03 medical and health sciences, Evolutionary biology, Viral evolution, Epistasis, Selection (genetic algorithm), 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4096bf5303e8504c6c51ef5734d46410
https://doi.org/10.1101/090258

المؤلفون: Shilpa Sambashivan, Mauricio Montal, Axel T. Brunger, Audrey Fischer

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Botulinum Neurotoxin, Stereochemistry, Endocytic cycle, Protein domain, Membrane Reconstitution, Peptide Mapping, Biochemistry, Ion Channels, Protein Structure, Secondary, Cell Line, Protein Translocases, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, Humans, Neurotoxin, Botulinum Toxins, Type A, Molecular Biology, Protein secondary structure, Ion channel, 030304 developmental biology, 0303 health sciences, Transmembrane channels, Protein Translocation, Membranes, biology, Patch Clamp, Chemistry, Proton-Motive Force, Membrane Proteins, Botulism, Cell Biology, equipment and supplies, Single Channels, Transmembrane protein, Protein Structure, Tertiary, Chaperone (protein), Biophysics, biology.protein, human activities, 030217 neurology & neurosurgery, Molecular Chaperones, Reports

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfeea6f55ae416d7e6dad260bf2650ca
https://doi.org/10.1074/jbc.c111.319400

المؤلفون: Brad L. Pentelute, R. John Collier, Matthew A. Holden, Audrey Fischer

المصدر: Proceedings of the National Academy of Sciences. 108:16577-16581

مصطلحات موضوعية: Pore Forming Cytotoxic Proteins, Antigens, Bacterial, Multidisciplinary, Effector, Toxin, Anthrax toxin, Bilayer, Bacterial Toxins, Lipid Bilayers, Chromosomal translocation, Biological Sciences, Biology, medicine.disease_cause, Transport protein, Cell biology, Electrophysiology, Protein Transport, Membrane, medicine, Carrier Proteins, Lipid bilayer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9198fb184bc5f659c36a73855ffa894c
https://doi.org/10.1073/pnas.1113074108

المؤلفون: Grégory Vernier, Audrey Fischer, Laura D. Jennings, Jianjun Sun, Jie Wang, R. John Collier, Likai Song

المصدر: Protein Science. 18:1882-1895

مصطلحات موضوعية: Circular dichroism, Crystallography, Transmembrane domain, chemistry.chemical_compound, Protein structure, Chemistry, Anthrax toxin, Helix, Lipid bilayer, Molecular Biology, Biochemistry, Micelle, Oligomer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d5f3f40ed5980ec5d135a03a33948f34
https://doi.org/10.1002/pro.199

المؤلفون: Colin M. Clancy, Audrey Fischer, William H. Tepp, Kim D. Janda, Sabine Pellett, Tobin J. Dickerson, Mauricio Montal, Eric A. Johnson, Yuya Nakai, Lisa M. Eubanks

المصدر: Proceedings of the National Academy of Sciences. 106:1330-1335

مصطلحات موضوعية: Botulinum Toxins, Patch-Clamp Techniques, Endosome, Chromosomal translocation, Pharmacology, Inhibitory postsynaptic potential, medicine.disease_cause, Mice, medicine, Animals, Neurotoxin, Botulism, Patch clamp, Cells, Cultured, Multidisciplinary, Activator (genetics), Chemistry, medicine.disease, Rats, Protein Transport, Spinal Cord, Biochemistry, Physical Sciences, Clostridium botulinum, Female, Drugs, Chinese Herbal

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64691e606910a536ff39e4aea8666b85
https://doi.org/10.1073/pnas.0812839106

المؤلفون: Mauricio Montal, Isin N. Geren, Audrey Fischer, James D. Marks, Terunaga Nakagawa, Jianlong Lou, Consuelo Garcia-Rodriguez

المصدر: Journal of Biological Chemistry. 283:3997-4003

مصطلحات موضوعية: Botulinum Toxins, Protease, Protein Conformation, medicine.drug_class, medicine.medical_treatment, Antibodies, Monoclonal, Cell Biology, Biology, Botulinum neurotoxin E, medicine.disease, Monoclonal antibody, Biochemistry, Molecular biology, Epitope, law.invention, Synaptic vesicle exocytosis, Microscopy, Electron, law, medicine, biology.protein, Electrophoresis, Polyacrylamide Gel, Botulism, Electron microscope, Antibody, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502c067d86ae2fac52195dfa62419c4e
https://doi.org/10.1074/jbc.m707917200

المؤلفون: Audrey Fischer, Mauricio Montal

المصدر: Journal of Biological Chemistry. 282:29604-29611

مصطلحات موضوعية: Protein Denaturation, Protein Folding, Botulinum Toxins, Patch-Clamp Techniques, Time Factors, Endosome, Disulfide Linkage, Chromosomal translocation, Models, Biological, Biochemistry, Exocytosis, Cytosol, Cell Line, Tumor, Endopeptidases, Clostridium botulinum, Humans, Disulfides, Molecular Biology, biology, Chemistry, Cell Membrane, Cell Biology, Transport protein, Protein Transport, Chaperone (protein), biology.protein, Biophysics, Protein folding, Peptide Hydrolases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a55d26d52b5daa0a1b1dfe5d0aa95c
https://doi.org/10.1074/jbc.m703619200