المؤلفون: Kellaway, Sophie G., Potluri, Sandeep, Keane, Peter, Blair, Helen J., Ames, Luke, Worker, Alice, Chin, Paulynn S., Ptasinska, Anetta, Derevyanko, Polina K., Adamo, Assunta, Coleman, Daniel J. L., Khan, Naeem, Assi, Salam A., Krippner-Heidenreich, Anja, Raghavan, Manoj, Cockerill, Peter N., Heidenreich, Olaf, Bonifer, Constanze

مصطلحات موضوعية: General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Multidisciplinary

Relation: https://nottingham-repository.worktribe.com/output/31603025; Nature Communications; Volume 15; Issue 1

الاتاحة: https://doi.org/10.1038/s41467-024-45691-4
https://nottingham-repository.worktribe.com/file/31603025/1/s41467-024-45691-4
https://nottingham-repository.worktribe.com/output/31603025

المؤلفون: Potluri, Sandeep, Kellaway, Sophie G, Coleman, Daniel J L, Keane, Peter, Imperato, Maria Rosaria, Assi, Salam A, Cockerill, Peter N, Bonifer, Constanze

مصطلحات موضوعية: Acute myeloid leukaemia, Cancer genomics, Oncogenes

Relation: https://nottingham-repository.worktribe.com/output/30105703; Leukemia; Volume 38; Issue 2; Pagination 403–407

الاتاحة: https://doi.org/10.1038/s41375-023-02118-1
https://nottingham-repository.worktribe.com/file/30105703/1/Gene%20regulation%20in%20t%286%3B9%29%20DEK%3A%3ANUP214%20Acute%20Myeloid%20Leukemia%20resembles%20that%20of%20FLT3-ITD%2FNPM1%20Acute%20Myeloid%20Leukemia%20but%20with%20an%20altered%20HOX%2FMEIS%20axis
https://nottingham-repository.worktribe.com/output/30105703

المؤلفون: Adamo, Assunta, Chin, Paulynn, Keane, Peter, Assi, Salam A., Potluri, Sandeep, Kellaway, Sophie G., Coleman, Daniel, Ames, Luke, Ptasinska, Anetta, Delwel, H. Ruud, Cockerill, Peter N., Bonifer, Constanze

المصدر: Adamo , A , Chin , P , Keane , P , Assi , S A , Potluri , S , Kellaway , S G , Coleman , D , Ames , L , Ptasinska , A , Delwel , H R , Cockerill , P N & Bonifer , C 2023 , ' Identification and interrogation of the gene regulatory network of CEBPA-double mutant acute myeloid leukemia ' , Leukemia , vol. 37 , no. 1 , pp. 102-112 . https://doi.org/10.1038/s41375-022-01744-5

مصطلحات موضوعية: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

الاتاحة: https://pure.eur.nl/en/publications/2f3c1c84-5813-4efa-8208-146817e95945
https://doi.org/10.1038/s41375-022-01744-5
https://pure.eur.nl/ws/files/73377026/Identification_and_interrogation_of_the_gene_regulatory_network_of_CEBPA_double_mutant_acute_myeloid_leukemia.pdf
http://www.scopus.com/inward/record.url?scp=85141357337&partnerID=8YFLogxK

المؤلفون: Coleman, Daniel J.L., Keane, Peter, Luque-Martin, Rosario, Chin, Paulynn S., Blair, Helen, Ames, Luke, Kellaway, Sophie G., Griffin, James, Holmes, Elizabeth, Potluri, Sandeep, Assi, Salam A., Bushweller, John, Heidenreich, Olaf, Cockerill, Peter N., Bonifer, Constanze

مصطلحات موضوعية: FLT3-ITD acute myeloid leukemia, gene regulatory networks, shRNA drop-out screen, transcription factor regulatory modules, RUNX1 dependency

Relation: https://nottingham-repository.worktribe.com/output/31445811; Cell Reports; Volume 42; Issue 12

الاتاحة: https://doi.org/10.1016/j.celrep.2023.113568
https://nottingham-repository.worktribe.com/file/31445811/1/Gene%20regulatory%20network%20analysis%20predicts%20cooperating%20transcription%20factor%20regulons%20required%20for%20FLT3-ITD%2B%20AML%20growth
https://nottingham-repository.worktribe.com/output/31445811

المؤلفون: Schleussner, Nikolai, Cauchy, Pierre, Franke, Vedran, Giefing, Maciej, Fornes, Oriol, Vankadari, Naveen, Assi, Salam A., Costanza, Mariantonia, Weniger, Marc A., Akalin, Altuna, Anagnostopoulos, Ioannis, Bukur, Thomas, Casarotto, Marco G., Damm, Frederik, Daumke, Oliver, Edginton-White, Benjamin, Gebhardt, J. Christof M., Grau, Michael, Grunwald, Stephan, Hansmann, Martin-Leo, Hartmann, Sylvia, Huber, Lionel, Kärgel, Eva, Lusatis, Simone, Noerenberg, Daniel, Obier, Nadine, Pannicke, Ulrich, Fischer, Anja, Reisser, Anja, Rosenwald, Andreas, Schwarz, Klaus, Sundararaj, Srinivasan, Weilemann, Andre, Winkler, Wiebke, Xu, Wendan, Lenz, Georg, Rajewsky, Klaus, Wasserman, Wyeth W., Cockerill, Peter N., Scheidereit, Claus, Siebert, Reiner, Küppers, Ralf, Grosschedl, Rudolf, Janz, Martin, Bonifer, Constanze, Mathas, Stephan

المساهمون: Gouvernement du Canada | Canadian Institutes of Health Research, Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada, Wilhelm Sander-Stiftung, Deutsche Krebshilfe, Max-Planck-Gesellschaft, Deutsche Forschungsgemeinschaft, Kay Kendall Leukaemia Fund

المصدر: Nature Communications ; volume 14, issue 1 ; ISSN 2041-1723

الاتاحة: http://dx.doi.org/10.1038/s41467-023-41954-8
https://www.nature.com/articles/s41467-023-41954-8.pdf
https://www.nature.com/articles/s41467-023-41954-8

المؤلفون: Tirtakusuma, Ricky, Szoltysek, Katarzyna, Milne, Paul, Grinev, Vasily V, Ptasinska, Anetta, Chin, Paulynn S, Meyer, Claus, Nakjang, Sirintra, Hehir-Kwa, Jayne Y, Williamson, Daniel, Cauchy, Pierre, Keane, Peter, Assi, Salam A, Ashtiani, Minoo, Kellaway, Sophie G, Imperato, Maria R, Vogiatzi, Fotini, Schweighart, Elizabeth K, Lin, Shan, Wunderlich, Mark, Stutterheim, Janine, Komkov, Alexander, Zerkalenkova, Elena, Evans, Paul, McNeill, Hesta, Elder, Alex, Martinez-Soria, Natalia, Fordham, Sarah E, Shi, Yuzhe, Russell, Lisa J, Pal, Deepali, Smith, Alex, Kingsbury, Zoya, Becq, Jennifer, Eckert, Cornelia, Haas, Oskar A, Carey, Peter, Bailey, Simon, Skinner, Roderick, Miakova, Natalia, Collin, Matthew, Bigley, Venetia, Haniffa, Muzlifah, Marschalek, Rolf, Harrison, Christine J, Cargo, Catherine A, Schewe, Denis, Olshanskaya, Yulia, Thirman, Michael J, Cockerill, Peter N, Mulloy, James C, Blair, Helen J, Vormoor, Josef, Allan, James M, Bonifer, Constanze, Heidenreich, Olaf, Bomken, Simon

المساهمون: Onderzoek Beeld, Cancer

مصطلحات موضوعية: Chromatin, Epigenesis, Genetic, Genes, Regulator, Humans, Myeloid-Lymphoid Leukemia Protein/genetics, Oncogene Proteins, Fusion/genetics, Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics, Hematology, Biochemistry, Cell Biology, Immunology, Journal Article

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/448774

الاتاحة: https://dspace.library.uu.nl/handle/1874/448774

المؤلفون: Cockerill, Peter, Assi, Salam, Bonifer, Constanze, Bushweller, John, Chin, Paulynn, Coleman, Daniel, Holmes, Elisabeth, Keane, Peter

المصدر: Experimental Hematology ; volume 111, page S71 ; ISSN 0301-472X

الاتاحة: http://dx.doi.org/10.1016/j.exphem.2022.07.109
https://api.elsevier.com/content/article/PII:S0301472X22003873?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0301472X22003873?httpAccept=text/plain

المؤلفون: Kellaway, Sophie, Potluri, Sandeep, Ames, Luke, Keane, Peter, Chin, Paulynn, Ptasinska, Anetta, Assi, Salam, Worker, Alice, Blair, Helen, Heidenreich, Olaf, Cockerill, Peter, Bonifer, Constanze

المصدر: Experimental Hematology ; volume 111, page S101 ; ISSN 0301-472X

الاتاحة: http://dx.doi.org/10.1016/j.exphem.2022.07.169
https://api.elsevier.com/content/article/PII:S0301472X22004477?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0301472X22004477?httpAccept=text/plain

المؤلفون: Maytum, Alexander, Ames, Luke, Assi, Salam, Bonifer, Constanze, Cazier, Jean-Baptiste, Clarke, Mary, Cockerill, Peter, Edginton-White, Benjamin, Göttgens, Bertie, Goode, Debbie, Keane, Peter, Kellaway, Sophie, Pagnuco, Inti

المصدر: Experimental Hematology ; volume 111, page S111 ; ISSN 0301-472X

الاتاحة: http://dx.doi.org/10.1016/j.exphem.2022.07.188
https://api.elsevier.com/content/article/PII:S0301472X22004660?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0301472X22004660?httpAccept=text/plain

المؤلفون: Grinev, Vasily V., Barneh, Farnaz, Ilyushonak, Ilya M., Nakjang, Sirintra, Smink, Job, van Oort, Anita, Clough, Richard, Seyani, Michael, McNeill, Hesta, Reza, Mojgan, Martinez-Soria, Natalia, Assi, Salam A., Ramanouskaya, Tatsiana V., Bonifer, Constanze, Heidenreich, Olaf

المساهمون: Bloodwise, Cancer Research UK, Stichting Kinderen Kankervrij, Kay Kendall Leukaemia Fund, North of England Children’s Cancer Research Fund

المصدر: Nature Communications ; volume 12, issue 1 ; ISSN 2041-1723

الاتاحة: http://dx.doi.org/10.1038/s41467-020-20848-z
https://www.nature.com/articles/s41467-020-20848-z.pdf
https://www.nature.com/articles/s41467-020-20848-z

المؤلفون: Potluri, Sandeep, Assi, Salam A., Chin, Paulynn S., Coleman, Dan J.L., Pickin, Anna, Moriya, Shogo, Seki, Naohiko, Heidenreich, Olaf, Cockerill, Peter N., Bonifer, Constanze

المصدر: Cell Reports ; volume 35, issue 3, page 109010 ; ISSN 2211-1247

الاتاحة: http://dx.doi.org/10.1016/j.celrep.2021.109010
https://api.elsevier.com/content/article/PII:S2211124721003247?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2211124721003247?httpAccept=text/plain

المؤلفون: Chin, Paulynn Suyin, Assi, Salam A., Ptasinska, Anetta, Imperato, Maria Rosaria, Cockerill, Peter N., Bonifer, Constanze

المساهمون: Bloodwise

المصدر: Experimental Hematology ; volume 92, page 62-74 ; ISSN 0301-472X

الاتاحة: http://dx.doi.org/10.1016/j.exphem.2020.10.005
https://api.elsevier.com/content/article/PII:S0301472X20306184?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0301472X20306184?httpAccept=text/plain

المؤلفون: Ptasinska, Anetta, Pickin, Anna, Assi, Salam A., Chin, Paulynn Suyin, Ames, Luke, Avellino, Roberto, Gröschel, Stephan, Delwel, Ruud, Cockerill, Peter N., Osborne, Cameron S., Bonifer, Constanze

المصدر: Ptasinska , A , Pickin , A , Assi , S A , Chin , P S , Ames , L , Avellino , R , Gröschel , S , Delwel , R , Cockerill , P N , Osborne , C S & Bonifer , C 2019 , ' RUNX1-ETO Depletion in t(8
21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction ' , Cell Reports , vol. 28 , no. 12 , pp. 3022-3031.e7 . https://doi.org/10.1016/j.celrep.2019.08.040

مصطلحات موضوعية: acute myeloid leukemia, AP-1 signaling in acute myeloid leukemia, chromatin programming, epigenetic regulation, integrated analysis of high-throughput data, Promoter-Capture Hi-C, promoter-enhancer interactions, RUNX1-ETO, transcription factors, transcriptional networks

الاتاحة: https://kclpure.kcl.ac.uk/portal/en/publications/c3181e33-9849-4d8d-b70c-e25a905ad56c
https://doi.org/10.1016/j.celrep.2019.08.040
http://www.scopus.com/inward/record.url?scp=85071724329&partnerID=8YFLogxK

المؤلفون: Vijayabaskar, M S, Goode, Debbie K, Obier, Nadine, Lichtinger, Monika, Emmett, Amber M L, Abidin, Fatin N Zainul, Shar, Nisar, Hannah, Rebecca, Assi, Salam A, Lie-A-Ling, Michael, Gottgens, Berthold, Lacaud, Georges, Kouskoff, Valerie, Bonifer, Constanze, Westhead, David R

المصدر: Vijayabaskar , M S , Goode , D K , Obier , N , Lichtinger , M , Emmett , A M L , Abidin , F N Z , Shar , N , Hannah , R , Assi , S A , Lie-A-Ling , M , Gottgens , B , Lacaud , G , Kouskoff , V , Bonifer , C & Westhead , D R 2019 , ' Identification of gene specific cis-regulatory elements during differentiation of mouse embryonic stem cells : An integrative approach using high-throughput datasets ' , PLoS computational biology , vol. 15 , ....

مصطلحات موضوعية: Animals, Cell Differentiation/genetics, Chromatin/metabolism, Databases, Genetic, Epigenesis, Epigenomics, Gene Expression Regulation/genetics, Genome, High-Throughput Screening Assays/methods, Macrophages/metabolism, Mice, Mouse Embryonic Stem Cells/metabolism, Myocytes, Cardiac/metabolism, Promoter Regions, Regulatory Elements, Transcriptional/genetics, Regulatory Sequences, Nucleic Acid, Transcription Factors/metabolism, ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

وصف الملف: application/pdf

الاتاحة: https://research.manchester.ac.uk/en/publications/b07e57fd-971c-41c5-8312-a91422db0aaa
https://doi.org/10.1371/journal.pcbi.1007337
https://pure.manchester.ac.uk/ws/files/173317987/journal.pcbi.1007337.pdf

المؤلفون: Assi, Salam A, Bonifer, Constanze, Cockerill, Peter N

المصدر: Cancer Informatics ; volume 18, page 117693511985986 ; ISSN 1176-9351 1176-9351

الاتاحة: http://dx.doi.org/10.1177/1176935119859863
http://journals.sagepub.com/doi/pdf/10.1177/1176935119859863
http://journals.sagepub.com/doi/full-xml/10.1177/1176935119859863

المؤلفون: Martinez-Soria, Natalia, McKenzie, Lynsey, Draper, Julia, Ptasinska, Anetta, Issa, Hasan, Potluri, Sandeep, Blair, Helen J., Pickin, Anna, Isa, Asmida, Chin, Paulynn Suyin, Tirtakusuma, Ricky, Coleman, Daniel, Nakjang, Sirintra, Assi, Salam, Forster, Victoria, Reza, Mojgan, Law, Ed, Berry, Philip, Mueller, Dorothee, Osborne, Cameron, Elder, Alex, Bomken, Simon N., Pal, Deepali, Allan, James M., Veal, Gareth J., Cockerill, Peter N., Wichmann, Christian, Vormoor, Josef, Lacaud, Georges, Bonifer, Constanze, Heidenreich, Olaf

المصدر: Cancer Cell ; volume 35, issue 4, page 705 ; ISSN 1535-6108

الاتاحة: https://doi.org/10.1016/j.ccell.2019.03.012
https://api.elsevier.com/content/article/PII:S1535610819301588?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1535610819301588?httpAccept=text/plain

المؤلفون: Martinez-Soria, Natalia, McKenzie, Lynsey, Draper, Julia, Ptasinska, Anetta, Issa, Hasan, Potluri, Sandeep, Blair, Helen J., Pickin, Anna, Isa, Asmida, Chin, Paulynn Suyin, Tirtakusuma, Ricky, Coleman, Daniel, Nakjang, Sirintra, Assi, Salam, Forster, Victoria, Reza, Mojgan, Law, Ed, Berry, Philip, Mueller, Dorothee, Elder, Alex, Bomken, Simon N., Pal, Deepali, Allan, James M., Veal, Gareth J., Cockerill, Peter N., Wichmann, Christian, Vormoor, Josef, Lacaud, Georges, Bonifer, Constanze, Heidenreich, Olaf

مصطلحات موضوعية: B900 Others in Subjects allied to Medicine, C400 Genetics

وصف الملف: text

Relation: https://nrl.northumbria.ac.uk/id/eprint/38490/1/Martinez-Soria%20et%20al%20-%20The%20Oncogenic%20Transcription%20Factor%20RUNX1-ETO%20OA.pdf; Martinez-Soria, Natalia, McKenzie, Lynsey, Draper, Julia, Ptasinska, Anetta, Issa, Hasan, Potluri, Sandeep, Blair, Helen J., Pickin, Anna, Isa, Asmida, Chin, Paulynn Suyin, Tirtakusuma, Ricky, Coleman, Daniel, Nakjang, Sirintra, Assi, Salam, Forster, Victoria, Reza, Mojgan, Law, Ed, Berry, Philip, Mueller, Dorothee, Elder, Alex, Bomken, Simon N., Pal, Deepali, Allan, James M., Veal, Gareth J., Cockerill, Peter N., Wichmann, Christian, Vormoor, Josef, Lacaud, Georges, Bonifer, Constanze and Heidenreich, Olaf (2018) The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation. Cancer Cell, 34 (4). 626-642.e8. ISSN 1535-6108

الاتاحة: https://nrl.northumbria.ac.uk/id/eprint/38490/
https://doi.org/10.1016/j.ccell.2018.08.015
https://nrl.northumbria.ac.uk/id/eprint/38490/1/Martinez-Soria%20et%20al%20-%20The%20Oncogenic%20Transcription%20Factor%20RUNX1-ETO%20OA.pdf

المؤلفون: Edginton-White, Benjamin, Cauchy, Pierre, Assi, Salam A., Hartmann, Sylvia, Riggs, Arthur G., Mathas, Stephan, Cockerill, Peter N., Bonifer, Constanze

المساهمون: Kay Kendall Leukaemia Fund

المصدر: Leukemia ; volume 33, issue 6, page 1463-1474 ; ISSN 0887-6924 1476-5551

الاتاحة: http://dx.doi.org/10.1038/s41375-018-0311-x
http://www.nature.com/articles/s41375-018-0311-x.pdf
http://www.nature.com/articles/s41375-018-0311-x

المؤلفون: Gilmour, Jane, Assi, Salam A., Noailles, Laura, Lichtinger, Monika, Obier, Nadine, Bonifer, Constanze

المساهمون: Biotechnology and Biological Sciences Research Council, Bloodwise (Formerly Leukaemia and Lymphoma Research): Grant number 15001

المصدر: Scientific Reports ; volume 8, issue 1 ; ISSN 2045-2322

الاتاحة: http://dx.doi.org/10.1038/s41598-018-28506-7
https://www.nature.com/articles/s41598-018-28506-7.pdf
https://www.nature.com/articles/s41598-018-28506-7

المؤلفون: Kellaway, Sophie, Kakkad, Regha, Keane, Peter, Assi, Salam, Bonifer, Constanze

المصدر: Experimental Hematology ; volume 64, page S76 ; ISSN 0301-472X

الاتاحة: http://dx.doi.org/10.1016/j.exphem.2018.06.261
https://api.elsevier.com/content/article/PII:S0301472X18305563?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0301472X18305563?httpAccept=text/plain