المؤلفون: Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman

المصدر: PLoS ONE, Vol 19, Iss 2 (2024)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10868801/?tool=EBI; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/632029072d364621ab5af8407af4ce1b

المؤلفون: Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Immunology, Developmental Biology, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, tandem sh2 domains, compounds lack selectivity, based activation motif, alzheimer &# 8217, doubly phosphorylated itam, since syk activation, fc receptor complexes, exacerbate ad pathology, itam , fc receptor, itam ), throughput screen, syk interacts, small molecules, putative targets, orthogonally assessed

Relation: https://figshare.com/articles/journal_contribution/uHTS_follow-up_structures_and_associated_data_/25228433

الاتاحة: https://doi.org/10.1371/journal.pone.0293548.s001
https://figshare.com/articles/journal_contribution/uHTS_follow-up_structures_and_associated_data_/25228433

المؤلفون: Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Immunology, Developmental Biology, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, tandem sh2 domains, compounds lack selectivity, based activation motif, alzheimer &# 8217, doubly phosphorylated itam, since syk activation, fc receptor complexes, exacerbate ad pathology, itam , fc receptor, itam ), throughput screen, syk interacts, small molecules, putative targets, orthogonally assessed

Relation: https://figshare.com/articles/journal_contribution/Measurements_of_solubility_of_compounds_13_and_37_in_PBS_by_nephelometer_/25228448

الاتاحة: https://doi.org/10.1371/journal.pone.0293548.s006
https://figshare.com/articles/journal_contribution/Measurements_of_solubility_of_compounds_13_and_37_in_PBS_by_nephelometer_/25228448

المؤلفون: Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Immunology, Developmental Biology, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, tandem sh2 domains, compounds lack selectivity, based activation motif, alzheimer &# 8217, doubly phosphorylated itam, since syk activation, fc receptor complexes, exacerbate ad pathology, itam , fc receptor, itam ), throughput screen, syk interacts, small molecules, putative targets, orthogonally assessed

Relation: https://figshare.com/articles/journal_contribution/Mass_spectrometry_of_compound_44_incubated_at_30_and_100_M_at_rt_for_1_h_with_proteins_/25228451

الاتاحة: https://doi.org/10.1371/journal.pone.0293548.s007
https://figshare.com/articles/journal_contribution/Mass_spectrometry_of_compound_44_incubated_at_30_and_100_M_at_rt_for_1_h_with_proteins_/25228451

المؤلفون: Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Immunology, Developmental Biology, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, tandem sh2 domains, compounds lack selectivity, based activation motif, alzheimer &# 8217, doubly phosphorylated itam, since syk activation, fc receptor complexes, exacerbate ad pathology, itam , fc receptor, itam ), throughput screen, syk interacts, small molecules, putative targets, orthogonally assessed

Relation: https://figshare.com/articles/journal_contribution/Spectral_characterization_of_compound_44_/25228457

الاتاحة: https://doi.org/10.1371/journal.pone.0293548.s009
https://figshare.com/articles/journal_contribution/Spectral_characterization_of_compound_44_/25228457

المؤلفون: Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Immunology, Developmental Biology, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, tandem sh2 domains, compounds lack selectivity, based activation motif, alzheimer &# 8217, doubly phosphorylated itam, since syk activation, fc receptor complexes, exacerbate ad pathology, itam , fc receptor, itam ), throughput screen, syk interacts, small molecules, putative targets, orthogonally assessed

Relation: https://figshare.com/articles/journal_contribution/Original_uncropped_and_unadjusted_images_underlying_blots_or_gels_/25228454

الاتاحة: https://doi.org/10.1371/journal.pone.0293548.s008
https://figshare.com/articles/journal_contribution/Original_uncropped_and_unadjusted_images_underlying_blots_or_gels_/25228454

المؤلفون: Michael L. Mohler, Arunima Sikdar, Suriyan Ponnusamy, Dong-Jin Hwang, Yali He, Duane D. Miller, Ramesh Narayanan

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 4; Pages: 2124

مصطلحات موضوعية: prostate cancer, castration-resistant prostate cancer (CRPC), androgen receptor (AR), selective AR degraders (SARD), non-canonical

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Oncology; https://dx.doi.org/10.3390/ijms22042124

الاتاحة: https://doi.org/10.3390/ijms22042124

المؤلفون: Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Immunology, Developmental Biology, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, tandem sh2 domains, compounds lack selectivity, based activation motif, alzheimer &# 8217, doubly phosphorylated itam, since syk activation, fc receptor complexes, exacerbate ad pathology, itam , fc receptor, itam ), throughput screen, syk interacts, small molecules, putative targets, orthogonally assessed

Relation: https://figshare.com/articles/figure/Gel_filtration_fractions_and_intact_mass_deconvolution_of_purified_SYK_proteins_/25228436

الاتاحة: https://doi.org/10.1371/journal.pone.0293548.s002
https://figshare.com/articles/figure/Gel_filtration_fractions_and_intact_mass_deconvolution_of_purified_SYK_proteins_/25228436

المؤلفون: Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Immunology, Developmental Biology, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, tandem sh2 domains, compounds lack selectivity, based activation motif, alzheimer &# 8217, doubly phosphorylated itam, since syk activation, fc receptor complexes, exacerbate ad pathology, itam , fc receptor, itam ), throughput screen, syk interacts, small molecules, putative targets, orthogonally assessed

Relation: https://figshare.com/articles/figure/Second_biological_replicate_of_GST-PD_data_displayed_in_Fig_4B_and_dose-response_GST-PD_for_compounds_4_and_32_/25228439

الاتاحة: https://doi.org/10.1371/journal.pone.0293548.s003
https://figshare.com/articles/figure/Second_biological_replicate_of_GST-PD_data_displayed_in_Fig_4B_and_dose-response_GST-PD_for_compounds_4_and_32_/25228439

المؤلفون: Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Immunology, Developmental Biology, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, tandem sh2 domains, compounds lack selectivity, based activation motif, alzheimer &# 8217, doubly phosphorylated itam, since syk activation, fc receptor complexes, exacerbate ad pathology, itam , fc receptor, itam ), throughput screen, syk interacts, small molecules, putative targets, orthogonally assessed

Relation: https://figshare.com/articles/figure/Secondary_biophysical_analyses_of_hit_compounds_via_BLI_/25228442

الاتاحة: https://doi.org/10.1371/journal.pone.0293548.s004
https://figshare.com/articles/figure/Secondary_biophysical_analyses_of_hit_compounds_via_BLI_/25228442

المؤلفون: Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Immunology, Developmental Biology, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, tandem sh2 domains, compounds lack selectivity, based activation motif, alzheimer &# 8217, doubly phosphorylated itam, since syk activation, fc receptor complexes, exacerbate ad pathology, itam , fc receptor, itam ), throughput screen, syk interacts, small molecules, putative targets, orthogonally assessed

Relation: https://figshare.com/articles/figure/Identification_of_active_disulfide_compounds_which_form_in_DMSO_solutions_of_compounds_42_and_43_/25228445

الاتاحة: https://doi.org/10.1371/journal.pone.0293548.s005
https://figshare.com/articles/figure/Identification_of_active_disulfide_compounds_which_form_in_DMSO_solutions_of_compounds_42_and_43_/25228445

المؤلفون: Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Immunology, Developmental Biology, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, tandem sh2 domains, compounds lack selectivity, based activation motif, alzheimer &# 8217, doubly phosphorylated itam, since syk activation, fc receptor complexes, exacerbate ad pathology, itam , fc receptor, itam ), throughput screen, syk interacts, small molecules, putative targets, orthogonally assessed

Relation: https://figshare.com/articles/figure/SYK_topology_and_activation_mechanism_with_Fc_receptors_/25228460

الاتاحة: https://doi.org/10.1371/journal.pone.0293548.g001
https://figshare.com/articles/figure/SYK_topology_and_activation_mechanism_with_Fc_receptors_/25228460

المؤلفون: Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Immunology, Developmental Biology, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, tandem sh2 domains, compounds lack selectivity, based activation motif, alzheimer &# 8217, doubly phosphorylated itam, since syk activation, fc receptor complexes, exacerbate ad pathology, itam , fc receptor, itam ), throughput screen, syk interacts, small molecules, putative targets, orthogonally assessed

Relation: https://figshare.com/articles/figure/Fig_2_-/25228463

الاتاحة: https://doi.org/10.1371/journal.pone.0293548.g002
https://figshare.com/articles/figure/Fig_2_-/25228463

المؤلفون: Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Immunology, Developmental Biology, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, tandem sh2 domains, compounds lack selectivity, based activation motif, alzheimer &# 8217, doubly phosphorylated itam, since syk activation, fc receptor complexes, exacerbate ad pathology, itam , fc receptor, itam ), throughput screen, syk interacts, small molecules, putative targets, orthogonally assessed

Relation: https://figshare.com/articles/figure/Compound_screening_cascade_and_the_development_and_use_of_a_biochemical_TR-FRET_assay_to_evaluate_inhibition_of_the_PPI_between_SYK-tSH2_and_the_FCERG1G_p-ITAM_peptide_/25228466

الاتاحة: https://doi.org/10.1371/journal.pone.0293548.g003
https://figshare.com/articles/figure/Compound_screening_cascade_and_the_development_and_use_of_a_biochemical_TR-FRET_assay_to_evaluate_inhibition_of_the_PPI_between_SYK-tSH2_and_the_FCERG1G_p-ITAM_peptide_/25228466

المؤلفون: Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Immunology, Developmental Biology, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, tandem sh2 domains, compounds lack selectivity, based activation motif, alzheimer &# 8217, doubly phosphorylated itam, since syk activation, fc receptor complexes, exacerbate ad pathology, itam , fc receptor, itam ), throughput screen, syk interacts, small molecules, putative targets, orthogonally assessed

Relation: https://figshare.com/articles/figure/Identification_of_3_compounds_that_inhibit_the_interaction_of_SYK_and_FCER1G_in_a_GST-SYK_and_FCER1G-Flag_pulldown_assay_/25228469

الاتاحة: https://doi.org/10.1371/journal.pone.0293548.g004
https://figshare.com/articles/figure/Identification_of_3_compounds_that_inhibit_the_interaction_of_SYK_and_FCER1G_in_a_GST-SYK_and_FCER1G-Flag_pulldown_assay_/25228469

المؤلفون: Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Immunology, Developmental Biology, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, tandem sh2 domains, compounds lack selectivity, based activation motif, alzheimer &# 8217, doubly phosphorylated itam, since syk activation, fc receptor complexes, exacerbate ad pathology, itam , fc receptor, itam ), throughput screen, syk interacts, small molecules, putative targets, orthogonally assessed

Relation: https://figshare.com/articles/figure/Compounds_13_and_37_react_covalently_with_SYK-tSH2_/25228472

الاتاحة: https://doi.org/10.1371/journal.pone.0293548.g005
https://figshare.com/articles/figure/Compounds_13_and_37_react_covalently_with_SYK-tSH2_/25228472

المؤلفون: Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Immunology, Developmental Biology, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, tandem sh2 domains, compounds lack selectivity, based activation motif, alzheimer &# 8217, doubly phosphorylated itam, since syk activation, fc receptor complexes, exacerbate ad pathology, itam , fc receptor, itam ), throughput screen, syk interacts, small molecules, putative targets, orthogonally assessed

Relation: https://figshare.com/articles/figure/Compound_44_covalently_modifies_SYK-tSH2_/25228475

الاتاحة: https://doi.org/10.1371/journal.pone.0293548.g006
https://figshare.com/articles/figure/Compound_44_covalently_modifies_SYK-tSH2_/25228475

المؤلفون: Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Immunology, Developmental Biology, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, tandem sh2 domains, compounds lack selectivity, based activation motif, alzheimer &# 8217, doubly phosphorylated itam, since syk activation, fc receptor complexes, exacerbate ad pathology, itam , fc receptor, itam ), throughput screen, syk interacts, small molecules, putative targets, orthogonally assessed

Relation: https://figshare.com/articles/figure/Compounds_13_37_and_44_100_M_bind_covalently_to_TBXT_and_MSN_via_mass_spectrometry_/25228478

الاتاحة: https://doi.org/10.1371/journal.pone.0293548.g007
https://figshare.com/articles/figure/Compounds_13_37_and_44_100_M_bind_covalently_to_TBXT_and_MSN_via_mass_spectrometry_/25228478

المؤلفون: Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Immunology, Developmental Biology, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, tandem sh2 domains, compounds lack selectivity, based activation motif, alzheimer &# 8217, doubly phosphorylated itam, since syk activation, fc receptor complexes, exacerbate ad pathology, itam , fc receptor, itam ), throughput screen, syk interacts, small molecules, putative targets, orthogonally assessed

Relation: https://figshare.com/articles/dataset/Biochemical_and_biophysical_data_for_compounds_37_13_42_43_and_44_/25228481

الاتاحة: https://doi.org/10.1371/journal.pone.0293548.t001
https://figshare.com/articles/dataset/Biochemical_and_biophysical_data_for_compounds_37_13_42_43_and_44_/25228481

المؤلفون: Arunima Sikdar, Rupali Gupta, Evzen Boura

المصدر: Current Molecular Pharmacology. 15:306-337

مصطلحات موضوعية: medicine.medical_specialty, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), Zika Virus Infection, business.industry, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Human immunodeficiency virus (HIV), Zika Virus, General Medicine, medicine.disease, medicine.disease_cause, Antiviral Agents, Acquired immunodeficiency syndrome (AIDS), Virus Diseases, Viruses, Humans, Medicine, business, Intensive care medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1097ad67de230be26318243067c74a0
https://doi.org/10.2174/1874467214666210804152836