المؤلفون: Ha Pham, Indira Singaram, Jiachen Sun, Arthur Ralko, Madalyn Puckett, Ashutosh Sharma, Alice Vrielink, Wonhwa Cho

المصدر: Journal of Lipid Research, Vol 63, Iss 3, Pp 100178- (2022)

مصطلحات موضوعية: cholesterol, site-specific depletion, cholesterol quantification, cholesterol signaling, plasma membrane, lysosomes, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227522000116; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/67900b1e0c7340ed8d66c5bd6f128625

المؤلفون: Pawanthi Buwaneka, Arthur Ralko, Shu-Lin Liu, Wonhwa Cho

المصدر: Journal of Lipid Research, Vol 62, Iss , Pp 100084- (2021)

مصطلحات موضوعية: cholesterol, plasma membrane, inner leaflet, transbilayer asymmetry, cholesterol availability, ratiometric sensors, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227521000663; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/2dcea8e0142c47f595ba89b3c6ddc68e

المؤلفون: Wonhwa Cho, Arthur Ralko, Indira Singaram, Daesung Lee, Ashutosh Sharma, Jiachen Sun

المصدر: ACS Chemical Biology. 15:1913-1920

مصطلحات موضوعية: 0301 basic medicine, In situ, Cell signaling, Quantitative imaging, 010405 organic chemistry, Chemistry, Spectral properties, Solvatochromism, Economic shortage, General Medicine, 01 natural sciences, Biochemistry, Fluorescence, 0104 chemical sciences, 03 medical and health sciences, 030104 developmental biology, Biophysics, Molecular Medicine, Molecule

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f52741447b383352b53ba3596c27276e
https://doi.org/10.1021/acschembio.0c00241

المؤلفون: Wonhwa Cho, Arthur Ralko, Ashutosh Sharma

المصدر: Hedgehog Signaling ISBN: 9781071617007

مصطلحات موضوعية: Patched, In situ, chemistry.chemical_compound, Membrane, Cholesterol transporter activity, chemistry, Cholesterol, Biophysics, lipids (amino acids, peptides, and proteins), Ligand (biochemistry), Hedgehog, Hedgehog signaling pathway

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8c7832a354859ec0845dab6f270688f8
https://doi.org/10.1007/978-1-0716-1701-4_4

المؤلفون: Wonhwa, Cho, Arthur, Ralko, Ashutosh, Sharma

المصدر: Methods in molecular biology (Clifton, N.J.). 2374

مصطلحات موضوعية: Patched Receptors, Patched-1 Receptor, Cholesterol, Cell Membrane, Animals, Membrane Proteins, Hedgehog Proteins, Fluorescence, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::552ff76a73371029964e8b1162c2ddd5
https://pubmed.ncbi.nlm.nih.gov/34562241

المؤلفون: Sukhamoy Gorai, Ha Pham, Pawanthi Buwaneka, Arthur Ralko, Wonhwa Cho

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Phosphatidylinositol 4,5-Diphosphate, WT, wild type, Phosphatidylinositol 3,4-bisphosphate, Receptor complex, GAPDH, glyceraldehyde 3-phosphate dehydrogenase, Receptor, Transforming Growth Factor-beta Type I, PI(3)P, phosphatidylinositol-3-phosphate, SMAD, Smad2 Protein, Biochemistry, EGFP, enhanced green fluorescence protein, TIRF, total internal reflection fluorescence, chemistry.chemical_compound, PI(4,5)P2, MH2 domain, Transforming Growth Factor beta, PLCδ, phospholipase Cδ, siRNA, short interference RNA, TMR, tetramethylrhodamine, Receptor, PH, pleckstrin homology domain, FRB, FKBP12-rapamycin binding domain of mTOR, POPC, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Cell biology, POPS, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoserine, Phosphatidylinositol 4,5-bisphosphate, PIP3, phosphatidylinositol-3,4,5-bisphosphate, PM, plasma membrane, Phosphorylation, SARA, Smad anchor for receptor activation, Signal transduction, Protein Binding, Signal Transduction, Research Article, TβR, transforming growth factor-β receptor, Active Transport, Cell Nucleus, SPR, surface plasmon resonance, LUVs, large unilamellar vesicles, TGF-β, transforming growth factor-β, Humans, EEs, early endosomes, Molecular Biology, membrane-protein interaction, PI(3,4)P2, phosphatidylinositol-3,4-bisphosphate, Phosphatidylinositol 3-phosphate, PtdInsP, phosphoinositide, Cell Biology, TGF-b, TGF-b receptor, chemistry, PI(4,5)P2, phosphatidylinositol-4,5-bisphosphate, plasma membrane targeting, FKBP12, 12 kDa FK506-binding protein, MH, Mad homology, Smad2, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef605ebedf237cc470093be8d892be72
https://pubmed.ncbi.nlm.nih.gov/34655614

المؤلفون: Shu-Lin Liu, Arthur Ralko, Pawanthi Buwaneka, Wonhwa Cho

المصدر: Journal of Lipid Research, Vol 62, Iss, Pp 100084-(2021)
Journal of Lipid Research

مصطلحات موضوعية: 0301 basic medicine, Phosphatidylinositol 4-phosphate, perfringolysin O toxin, 030204 cardiovascular system & hematology, plasma membrane, Biochemistry, Green fluorescent protein, EGFP, enhanced green fluorescence protein, PIP2, phosphoinositol-4,5-bisphosphate, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, cholesterol availability, HUVEC, human umbilical vein endothelial cell, IPM, inner leaflet of the plasma membrane, ratiometric sensors, HPAEC, human pulmonary artery endothelial cell, HLF, human lung fibroblast, quantitative fluorescence imaging, POPE, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethano8lamine, POPC, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Osh4, Cell biology, POPS, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoserine, SAPC, 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine, PM, plasma membrane, Human umbilical vein endothelial cell, lipids (amino acids, peptides, and proteins), inner leaflet, Research Article, Cell signaling, 25HC, 25-hydroxycholesterol, SPR, surface plasmon resonance, QD415-436, PI, phosphatidylinositol, 03 medical and health sciences, FP, fluorescence protein, Phosphatidylinositol, POPC, PI(4)P, phosphatidylinositol-4-phosphate, Cholesterol, Cell Membrane, cholesterol, Cell Biology, MEF, mouse embryonic fibroblast, OPM, outer leaflet of the plasma membrane, Cytosol, 030104 developmental biology, chemistry, GUV, giant unilamellar vesicle, cholesterol pools, transbilayer asymmetry, LUV, large unilamellar vesicle, SAG, 1-stearoyl-2-arachidonoyl-sn-glycerol, PFO, perfringolysin O

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98998a9fabc83fa3193c8196f2d33e15
http://www.sciencedirect.com/science/article/pii/S0022227521000663

المؤلفون: Guoping Pan, Otto K. Kari, Riikka Kosonen, Arthur Ralko, Annika Koponen, Vesa M. Olkkonen, Annukka M. Kivelä, Daoguang Yan, Amita Arora, Elina Ikonen, Wonhwa Cho, Juuso H. Taskinen, Joseph Ndika

المساهمون: Medicum, Faculty of Pharmacy, Research Services, Biopharmaceutics Group, Division of Pharmaceutical Biosciences, Drug Delivery Unit, Drug Research Program, HUMI - Human Microbiome Research, Faculty of Medicine, Lipid Trafficking Lab, Department of Anatomy, Doctoral Programme in Biomedicine, Doctoral Programme in Integrative Life Science, Doctoral Programme in Drug Research, STEMM - Stem Cells and Metabolism Research Program, Biosciences

مصطلحات موضوعية: Phosphatidylinositol 4,5-Diphosphate, 0301 basic medicine, Receptors, Steroid, Angiogenesis, Osbpl2, UP-REGULATION, Biochemistry, angiogenesis, 0302 clinical medicine, Cell Movement, Lipid raft, Receptors, Notch, Chemistry, TOR Serine-Threonine Kinases, VEGF receptor, Sterol homeostasis, Cadherins, Cell biology, cholesterol trafficking, Signal transduction, Oxysterol-binding protein, Signal Transduction, Biotechnology, GROWTH-FACTOR, SUPPRESSES ANGIOGENESIS, Nitric Oxide Synthase Type III, Notch signaling pathway, Neovascularization, Physiologic, VE-CADHERIN, Endosomes, Caveolins, 03 medical and health sciences, Antigens, CD, Human Umbilical Vein Endothelial Cells, Genetics, Humans, TRAFFICKING, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, RECEPTOR, Cell Membrane, Actins, Matrix Metalloproteinases, LIPID RAFTS, Receptors, Vascular Endothelial Growth Factor, 030104 developmental biology, MAMMALIAN TARGET, 1182 Biochemistry, cell and molecular biology, OXYSTEROL-BINDING-PROTEIN, 3111 Biomedicine, MEMBRANE, Proto-Oncogene Proteins c-akt, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f62e21565fe95a1958b8bbb87d2bf24d
http://hdl.handle.net/10138/352495

المؤلفون: Yifan Cheng, Arthur Ralko, David Bulkley, Wan Jin Lu, Philip A. Beachy, Shuo Han, Jiahao Liang, Kelsey J. Roberts, Aashish Manglik, Wonhwa Cho, Li A, Yunxiao Zhang

المصدر: Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 46
Proc Natl Acad Sci U S A

مصطلحات موضوعية: Agonist, Patched, Patched Receptors, medicine.drug_class, hedgehog, Cell, medicine, Animals, Humans, Hedgehog Proteins, Receptor, Hedgehog, Multidisciplinary, Chemistry, Cryoelectron Microscopy, Biological Sciences, Single-Domain Antibodies, Ligand (biochemistry), Hedgehog signaling pathway, Cell biology, Patched-1 Receptor, nanobody, medicine.anatomical_structure, PTCH1, transporter, cryo-EM, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e3379f48d6915d638a41a421f5f4df
https://escholarship.org/uc/item/9jz574rs

المؤلفون: Ashutosh, Sharma, Jiachen, Sun, Indira, Singaram, Arthur, Ralko, Daesung, Lee, Wonhwa, Cho

المصدر: ACS Chem Biol

مصطلحات موضوعية: Small Molecule Libraries, Fluorenes, Mice, Spectrometry, Fluorescence, Phosphatidylinositol Phosphates, NIH 3T3 Cells, Animals, Article, Fluorescent Dyes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::d75e9480b705073bb07132a108ea9ec8
https://pubmed.ncbi.nlm.nih.gov/32525312

المؤلفون: Jiahao Liang, Arthur Ralko, David P. Bulkley, Li A, Philip A. Beachy, Aashish Manglik, Yifan Cheng, Kelsey J. Roberts, Wan Jin Lu, Wonhwa Cho, Yunxiao Zhang

مصطلحات موضوعية: Patched, Agonist, medicine.anatomical_structure, medicine.drug_class, Chemistry, Regeneration (biology), Cell, medicine, Transporter, Receptor, Hedgehog, Hedgehog signaling pathway, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b34c65532b9c379a1f15b300ccc3add2
https://doi.org/10.1101/783290

المؤلفون: Cong, Wang, Arthur, Ralko, Zhong, Ren, Avia, Rosenhouse-Dantsker, Xiaojing, Yang

المصدر: Advances in experimental medicine and biology. 1135

مصطلحات موضوعية: Binding Sites, Cholesterol, Cell Membrane, Humans, Membrane Proteins, Receptors, Adrenergic, beta-2, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::a9324779bd3e0b477fa1f6f228bea3d8
https://pubmed.ncbi.nlm.nih.gov/31098811

المؤلفون: Gregory B. Kharas, William S. Schjerven, Uriel A. Baray, Samantha Chan, Michael T. Cole, Alexander F. Haddad, Joseph A. Lucente, Kayne J. Patterson, Arthur Ralko, Katie N. Reget, Catherine A. Shamblen, Emily M. Whitmore

المصدر: Journal of Macromolecular Science, Part A. 53:191-195

مصطلحات موضوعية: Polymers and Plastics, Materials Chemistry, Ceramics and Composites, General Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d588d12bfc474c5c8b7eda1fc69d022f
https://doi.org/10.1080/10601325.2016.1143310

المؤلفون: Xiaojing Yang, Avia Rosenhouse-Dantsker, Cong Wang, Arthur Ralko, Zhong Ren

المصدر: Advances in Experimental Medicine and Biology ISBN: 9783030142643

مصطلحات موضوعية: Cholesterol, Cholesterol binding, computer.file_format, Crystal structure, Protein Data Bank, Transmembrane protein, Cell membrane, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine.anatomical_structure, Membrane protein, chemistry, medicine, Biophysics, lipids (amino acids, peptides, and proteins), 030212 general & internal medicine, Receptor, computer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d9dfc9ce586094517eac2f1c451d9ba5
https://doi.org/10.1007/978-3-030-14265-0_4

المؤلفون: Ursula A. Perez-Salas, Yangmingyue Liu, Michael Stanfield, Neti Bhatt, Arthur Ralko, Justin Lorieau, Wonhwa Cho, Lionel Porcar, Yuri Gerelli

المصدر: Biophysical Journal. 116:328a

مصطلحات موضوعية: Biophysics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::247d193f1960c04626050ec198bab3e9
https://doi.org/10.1016/j.bpj.2018.11.1779