يعرض 1 - 11 نتائج من 11 نتيجة بحث عن '"Arodyn"', وقت الاستعلام: 0.39s تنقيح النتائج
  1. 1
    Academic Journal
    Conformational Constraint between Aromatic Residue Side Chains in the “Message” Sequence of the Peptide Arodyn Using Ring Closing Metathesis Results in a Potent and Selective Kappa Opioid Receptor Antagonist

    المؤلفون: Solomon A. Gisemba (8292918), Michael J. Ferracane (3114030), Thomas F. Murray (776850), Jane V. Aldrich (2332483)

    مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Physiology, Pharmacology, Biotechnology, Evolutionary Biology, Immunology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Selective Kappa Opioid Receptor Ant., KOR affinity, 15 nM, Arg 4, analog arodyn, KOR antagonist potency, KOR antagonism, Ring Closing Metathesis Results, Peptide Arodyn, allyl groups, Aromatic Residue Side Chains, para O, K B, drug addiction, Conformational Constraint, docking study, mood disorders, KOR selectivity

    Relation: https://figshare.com/articles/journal_contribution/Conformational_Constraint_between_Aromatic_Residue_Side_Chains_in_the_Message_Sequence_of_the_Peptide_Arodyn_Using_Ring_Closing_Metathesis_Results_in_a_Potent_and_Selective_Kappa_Opioid_Receptor_Antagonist/14192727

    الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c01984.s002

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  2. 2
    Academic Journal
    Design, synthesis, and opioid activity of arodyn analogs cyclized by ring-closing metathesis involving Tyr(allyl)

    المؤلفون: Department of Medicinal Chemistry, University of Kansas, Lawrence, KS 66045, USA ( host institution ), Fang, Wei-Jie ( author ), Murray, Thomas F. ( author ), Aldrich, Jane V. ( UF author )

    مصطلحات موضوعية: Arodyn, Ring-closing metathesis, Peptide cyclization, Kappa opioid receptor antagonists, Dynorphin A analogs, Tyrosine(allyl)

    وصف الملف: Pages

    Relation: Bioorganic & Medicinal Chemistry; S0968089617316553; http://ufdc.ufl.edu/LS00593109/00001

    الاتاحة: https://doi.org/10.1016/j.bmc.2017.11.029
    http://ufdc.ufl.edu/LS00593109/00001

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  3. 3
    Conformational Constraint between Aromatic Residue Side Chains in the “Message” Sequence of the Peptide Arodyn Using Ring Closing Metathesis Results in a Potent and Selective Kappa Opioid Receptor Antagonist

    المؤلفون: Solomon A. Gisemba (8292918), Michael J. Ferracane (3114030), Thomas F. Murray (776850), Jane V. Aldrich (2332483)

    مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Physiology, Pharmacology, Biotechnology, Evolutionary Biology, Immunology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Selective Kappa Opioid Receptor Ant., KOR affinity, 15 nM, Arg 4, analog arodyn, KOR antagonist potency, KOR antagonism, Ring Closing Metathesis Results, Peptide Arodyn, allyl groups, Aromatic Residue Side Chains, para O, K B, drug addiction, Conformational Constraint, docking study, mood disorders, KOR selectivity

    Relation: https://figshare.com/articles/dataset/Conformational_Constraint_between_Aromatic_Residue_Side_Chains_in_the_Message_Sequence_of_the_Peptide_Arodyn_Using_Ring_Closing_Metathesis_Results_in_a_Potent_and_Selective_Kappa_Opioid_Receptor_Antagonist/14192742

    الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c01984.s007

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  4. 4
    Conformational Constraint between Aromatic Residue Side Chains in the “Message” Sequence of the Peptide Arodyn Using Ring Closing Metathesis Results in a Potent and Selective Kappa Opioid Receptor Antagonist

    المؤلفون: Solomon A. Gisemba (8292918), Michael J. Ferracane (3114030), Thomas F. Murray (776850), Jane V. Aldrich (2332483)

    مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Physiology, Pharmacology, Biotechnology, Evolutionary Biology, Immunology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Selective Kappa Opioid Receptor Ant., KOR affinity, 15 nM, Arg 4, analog arodyn, KOR antagonist potency, KOR antagonism, Ring Closing Metathesis Results, Peptide Arodyn, allyl groups, Aromatic Residue Side Chains, para O, K B, drug addiction, Conformational Constraint, docking study, mood disorders, KOR selectivity

    Relation: https://figshare.com/articles/dataset/Conformational_Constraint_between_Aromatic_Residue_Side_Chains_in_the_Message_Sequence_of_the_Peptide_Arodyn_Using_Ring_Closing_Metathesis_Results_in_a_Potent_and_Selective_Kappa_Opioid_Receptor_Antagonist/14192733

    الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c01984.s004

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  5. 5
    Conformational Constraint between Aromatic Residue Side Chains in the “Message” Sequence of the Peptide Arodyn Using Ring Closing Metathesis Results in a Potent and Selective Kappa Opioid Receptor Antagonist

    المؤلفون: Solomon A. Gisemba (8292918), Michael J. Ferracane (3114030), Thomas F. Murray (776850), Jane V. Aldrich (2332483)

    مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Physiology, Pharmacology, Biotechnology, Evolutionary Biology, Immunology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Selective Kappa Opioid Receptor Ant., KOR affinity, 15 nM, Arg 4, analog arodyn, KOR antagonist potency, KOR antagonism, Ring Closing Metathesis Results, Peptide Arodyn, allyl groups, Aromatic Residue Side Chains, para O, K B, drug addiction, Conformational Constraint, docking study, mood disorders, KOR selectivity

    Relation: https://figshare.com/articles/dataset/Conformational_Constraint_between_Aromatic_Residue_Side_Chains_in_the_Message_Sequence_of_the_Peptide_Arodyn_Using_Ring_Closing_Metathesis_Results_in_a_Potent_and_Selective_Kappa_Opioid_Receptor_Antagonist/14192736

    الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c01984.s005

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  6. 6
    Conformational Constraint between Aromatic Residue Side Chains in the “Message” Sequence of the Peptide Arodyn Using Ring Closing Metathesis Results in a Potent and Selective Kappa Opioid Receptor Antagonist

    المؤلفون: Solomon A. Gisemba (8292918), Michael J. Ferracane (3114030), Thomas F. Murray (776850), Jane V. Aldrich (2332483)

    مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Physiology, Pharmacology, Biotechnology, Evolutionary Biology, Immunology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Selective Kappa Opioid Receptor Ant., KOR affinity, 15 nM, Arg 4, analog arodyn, KOR antagonist potency, KOR antagonism, Ring Closing Metathesis Results, Peptide Arodyn, allyl groups, Aromatic Residue Side Chains, para O, K B, drug addiction, Conformational Constraint, docking study, mood disorders, KOR selectivity

    Relation: https://figshare.com/articles/dataset/Conformational_Constraint_between_Aromatic_Residue_Side_Chains_in_the_Message_Sequence_of_the_Peptide_Arodyn_Using_Ring_Closing_Metathesis_Results_in_a_Potent_and_Selective_Kappa_Opioid_Receptor_Antagonist/14192730

    الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c01984.s003

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  7. 7
    Conformational Constraint between Aromatic Residue Side Chains in the “Message” Sequence of the Peptide Arodyn Using Ring Closing Metathesis Results in a Potent and Selective Kappa Opioid Receptor Antagonist

    المؤلفون: Solomon A. Gisemba (8292918), Michael J. Ferracane (3114030), Thomas F. Murray (776850), Jane V. Aldrich (2332483)

    مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Physiology, Pharmacology, Biotechnology, Evolutionary Biology, Immunology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Selective Kappa Opioid Receptor Ant., KOR affinity, 15 nM, Arg 4, analog arodyn, KOR antagonist potency, KOR antagonism, Ring Closing Metathesis Results, Peptide Arodyn, allyl groups, Aromatic Residue Side Chains, para O, K B, drug addiction, Conformational Constraint, docking study, mood disorders, KOR selectivity

    Relation: https://figshare.com/articles/dataset/Conformational_Constraint_between_Aromatic_Residue_Side_Chains_in_the_Message_Sequence_of_the_Peptide_Arodyn_Using_Ring_Closing_Metathesis_Results_in_a_Potent_and_Selective_Kappa_Opioid_Receptor_Antagonist/14192724

    الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c01984.s001

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  8. 8
    Conformational Constraint between Aromatic Residue Side Chains in the “Message” Sequence of the Peptide Arodyn Using Ring Closing Metathesis Results in a Potent and Selective Kappa Opioid Receptor Antagonist

    المؤلفون: Solomon A. Gisemba (8292918), Michael J. Ferracane (3114030), Thomas F. Murray (776850), Jane V. Aldrich (2332483)

    مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Physiology, Pharmacology, Biotechnology, Evolutionary Biology, Immunology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Selective Kappa Opioid Receptor Ant., KOR affinity, 15 nM, Arg 4, analog arodyn, KOR antagonist potency, KOR antagonism, Ring Closing Metathesis Results, Peptide Arodyn, allyl groups, Aromatic Residue Side Chains, para O, K B, drug addiction, Conformational Constraint, docking study, mood disorders, KOR selectivity

    Relation: https://figshare.com/articles/dataset/Conformational_Constraint_between_Aromatic_Residue_Side_Chains_in_the_Message_Sequence_of_the_Peptide_Arodyn_Using_Ring_Closing_Metathesis_Results_in_a_Potent_and_Selective_Kappa_Opioid_Receptor_Antagonist/14192739

    الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c01984.s006

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  9. 9
    Conformational Constraint between Aromatic Residue Side Chains in the “Message” Sequence of the Peptide Arodyn Using Ring Closing Metathesis Results in a Potent and Selective Kappa Opioid Receptor Antagonist

    المؤلفون: Solomon A. Gisemba (8292918), Michael J. Ferracane (3114030), Thomas F. Murray (776850), Jane V. Aldrich (2332483)

    مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Physiology, Pharmacology, Biotechnology, Evolutionary Biology, Immunology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Selective Kappa Opioid Receptor Ant., KOR affinity, 15 nM, Arg 4, analog arodyn, KOR antagonist potency, KOR antagonism, Ring Closing Metathesis Results, Peptide Arodyn, allyl groups, Aromatic Residue Side Chains, para O, K B, drug addiction, Conformational Constraint, docking study, mood disorders, KOR selectivity

    Relation: https://figshare.com/articles/dataset/Conformational_Constraint_between_Aromatic_Residue_Side_Chains_in_the_Message_Sequence_of_the_Peptide_Arodyn_Using_Ring_Closing_Metathesis_Results_in_a_Potent_and_Selective_Kappa_Opioid_Receptor_Antagonist/14192745

    الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c01984.s008

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  10. 10
    Dissertation/ Thesis
    Design and synthesis of cyclic analogs of the kappa opioid receptor antagonist arodyn

    المؤلفون: Gisemba, Solomon

    المساهمون: Peterson, Blake, Aldrich, Jane, Rafferty, Michael, Siahaan, Teruna, Tolbert, Thomas

    مصطلحات موضوعية: Chemistry, Pharmacology, Arodyn, Dynorphin A analogs, Kappa opioid receptor antagonists, Peptide cyclization, Ring-closing metathesis, Tyrosine(allyl)

    وصف الملف: 252 pages; application/pdf

    Relation: http://dissertations.umi.com/ku:16069; http://hdl.handle.net/1808/27579

    الاتاحة: http://hdl.handle.net/1808/27579
    http://dissertations.umi.com/ku:16069

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  11. 11
    Dissertation/ Thesis
    DESIGN, SYNTHESIS AND METABOLISM OF ARODYN ANALOGS

    المؤلفون: Dresner, Kendra Nelson

    المساهمون: Aldrich, Jane V, Lunte, Susan M., Prisinzano, Thomas E.

    مصطلحات موضوعية: Pharmaceutical chemistry, Arodyn, Drug addiction, Kappa opioid receptors, Opioid antagonists, Peptide drugs

    وصف الملف: 96 pages; application/pdf

    Relation: http://dissertations.umi.com/ku:10191; http://hdl.handle.net/1808/6184

    الاتاحة: http://hdl.handle.net/1808/6184
    http://dissertations.umi.com/ku:10191

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