المؤلفون: John K Thuita, Kristina K Wolf, Grace A Murilla, Arlene S Bridges, David W Boykin, James N Mutuku, Qiang Liu, Susan K Jones, Charles O Gem, Shelley Ching, Richard R Tidwell, Michael Z Wang, Mary F Paine, Reto Brun

المصدر: PLoS Neglected Tropical Diseases, Vol 9, Iss 2, p e0003409 (2015)

مصطلحات موضوعية: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4318582?pdf=render; https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

URL الوصول: https://doaj.org/article/aad4fdcad9934c25a153ed2b89ab73e9

المؤلفون: John K Thuita, Kristina K Wolf, Grace A Murilla, Qiang Liu, James N Mutuku, Yao Chen, Arlene S Bridges, Raymond E Mdachi, Mohamed A Ismail, Shelley Ching, David W Boykin, James Edwin Hall, Richard R Tidwell, Mary F Paine, Reto Brun, Michael Zhuo Wang

المصدر: PLoS Neglected Tropical Diseases, Vol 7, Iss 6, p e2230 (2013)

مصطلحات موضوعية: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3674995?pdf=render; https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

URL الوصول: https://doaj.org/article/3329b3b038db4c1fbbbafc2be436adde

المؤلفون: Julie K Hurt, Jennifer L Coleman, Brendan J Fitzpatrick, Bonnie Taylor-Blake, Arlene S Bridges, Pirkko Vihko, Mark J Zylka

المصدر: PLoS ONE, Vol 7, Iss 10, p e48562 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23119057/pdf/?tool=EBI; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/94a81905acde459b9e7dc4a62c01d6f9

المؤلفون: Koji Abe, Arlene S Bridges, Wei Yue, Kim L R Brouwer

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://jpet.aspetjournals.org/content/jpet/326/3/983.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1078.1715; http://jpet.aspetjournals.org/content/jpet/326/3/983.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1078.1715
http://jpet.aspetjournals.org/content/jpet/326/3/983.full.pdf

المؤلفون: James Edwin Hall, W. David Wilson, Reto Brun, David W. Boykin, Richard R, Qiyue Hu, Farial A. Tanious, Tanja Wenzler, Janelle Saulter, Arvind Kumar, Iris Francesconi, A M. Mathis, Arlene S. Bridges, Mohamed A. Ismail, Diphenyl Furans, Aza Analogs Effects

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://aac.asm.org/content/51/8/2801.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.522.9453; http://aac.asm.org/content/51/8/2801.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.522.9453
http://aac.asm.org/content/51/8/2801.full.pdf

المؤلفون: Giulia Ghibellini, Arlene S Bridges, Claudia N Generaux, Kim L R Brouwer

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://dmd.aspetjournals.org/content/dmd/early/2006/12/28/dmd.106.012278.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1087.7557; http://dmd.aspetjournals.org/content/dmd/early/2006/12/28/dmd.106.012278.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1087.7557
http://dmd.aspetjournals.org/content/dmd/early/2006/12/28/dmd.106.012278.full.pdf

المؤلفون: Xianbin Tian, Maciej J. Zamek-gliszczynski, Jun Li, Arlene S. Bridges, Ken-ichi Nezasa, Nita J. Patel, Thomas J. Raub, Kim L. R. Brouwer

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://dmd.aspetjournals.org/content/36/1/61.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.614.7246; http://dmd.aspetjournals.org/content/36/1/61.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.614.7246
http://dmd.aspetjournals.org/content/36/1/61.full.pdf

المؤلفون: Kim L. R. Brouwer, Nathan D. Pfeifer, Brian C. Ferslew, Rhiannon N. Hardwick, Arlene S. Bridges

المصدر: Journal of Pharmacology and Experimental Therapeutics. 347:737-745

مصطلحات موضوعية: Male, medicine.medical_specialty, Abcg2, Metabolism, Transport, and Pharmacogenomics, Excretion, Tandem Mass Spectrometry, Internal medicine, medicine, Animals, Bile, Rosuvastatin, Rosuvastatin Calcium, Biliary Tract, Pentanoic Acids, Cells, Cultured, Chromatography, High Pressure Liquid, Mice, Knockout, Pharmacology, Sulfonamides, biology, Multidrug resistance-associated protein 2, Rats, Fluorobenzenes, Pyrimidines, Endocrinology, Liver, Hepatocytes, biology.protein, Molecular Medicine, ATP-Binding Cassette Transporters, Efflux, Hepatic Elimination, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Carrier Proteins, Perfusion, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1556061840e38a2a0fbda8a1bfa4ad
https://doi.org/10.1124/jpet.113.208314

المؤلفون: Mary F. Paine, Dhiren R. Thakker, David W. Boykin, Richard R. Tidwell, Mohamed A. Ismail, Arlene S. Bridges, Claudia N. Generaux, Garrett R. Ainslie

المصدر: Drug Metabolism and Disposition. 41:518-528

مصطلحات موضوعية: Central Nervous System, Male, Stereochemistry, Kinetics, Pharmaceutical Science, Hydroxylation, Methylation, Models, Biological, Cytochrome P-450 Enzyme System, Species Specificity, Biotransformation, Animals, Humans, Prodrugs, Cells, Cultured, Demethylation, Pharmacology, chemistry.chemical_classification, Molecular Structure, CYP1A2, Prodrug, Trypanocidal Agents, Recombinant Proteins, Rats, Isoenzymes, Metabolic pathway, Enzyme, Liver, Biochemistry, chemistry, Dealkylation, Hepatocytes, Microsomes, Liver, Microsome, Female, Oxidation-Reduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246cbe7465926ee8114fa052479c62e9
https://doi.org/10.1124/dmd.112.048231

المؤلفون: Joyce A. Goldstein, Arlene S. Bridges, Melanie S. Joy, Yichun Hu, Mary Anne Dooley, Joyce Blaisdell, Kim L. R. Brouwer, Ronald J. Falk, Mary La, Jinzhao Wang, Reginald F. Frye, Susan L. Hogan

المصدر: British Journal of Clinical Pharmacology. 74:445-455

مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, education.field_of_study, Cyclophosphamide, business.industry, 4-Hydroxycyclophosphamide, Population, Lupus nephritis, Renal function, medicine.disease, Gastroenterology, Elimination rate constant, Pharmacokinetics, Internal medicine, medicine, Pharmacology (medical), Vasculitis, education, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e32295557b81618816acb253e7960a87
https://doi.org/10.1111/j.1365-2125.2012.04223.x

المؤلفون: Arlene S. Bridges, J. Heyward Hull, Paul B. Watkins, E. Claire Dees, Daniel L. Hertz, Christine M. Walko, Jill M Herendeen, Kristan D. Rollins

المصدر: British Journal of Clinical Pharmacology. 74:197-200

مصطلحات موضوعية: Pharmacology, CYP3A4, business.industry, Erythromycin breath test, chemistry.chemical_compound, Therapeutic index, Paclitaxel, chemistry, In vivo, Medicine, Pharmacology (medical), business, CYP2C8, Rosiglitazone, Drug metabolism, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78fde0471ffb7190f7272538c14486a3
https://doi.org/10.1111/j.1365-2125.2012.04165.x

المؤلفون: Jayalakshmi Miriyala, Hyeong Min Lee, Xin Chen, J. Walter Dutton, Bryan L. Roth, Noah Sciaky, Hsien-Sung Huang, John A. Allen, Angela M. Mabb, Bonnie Taylor-Blake, Mark J. Zylka, Jian Jin, Ian F. G. King, Arlene S. Bridges, Benjamin D. Philpot

المصدر: Nature

مصطلحات موضوعية: Male, congenital, hereditary, and neonatal diseases and abnormalities, Topoisomerase Inhibitors, medicine.drug_class, Ubiquitin-Protein Ligases, Drug Evaluation, Preclinical, Mothers, Biology, Article, Small Molecule Libraries, Fathers, Genomic Imprinting, Mice, 03 medical and health sciences, 0302 clinical medicine, Neurodevelopmental disorder, Angelman syndrome, UBE3A, medicine, Animals, Gene Silencing, Allele, Alleles, Cells, Cultured, Etoposide, 030304 developmental biology, Cerebral Cortex, Neurons, 0303 health sciences, Multidisciplinary, medicine.disease, 3. Good health, Mice, Inbred C57BL, Cancer research, Female, Topotecan, Angelman Syndrome, Genomic imprinting, 030217 neurology & neurosurgery, Topoisomerase inhibitor, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d13b6867a7a45822837f86cf6180cfe
https://doi.org/10.1038/nature10726

المؤلفون: Joseph L. Kelley, Thomas C. Krivak, Austin J. Combest, Angela Y. C. Yu, Robert P. Edwards, Julie A. DeLoia, Arlene S. Bridges, Christine M. Walko, Beth A. Zamboni, William C. Zamboni

المصدر: Cancer Chemotherapy and Pharmacology. 68:1255-1262

مصطلحات موضوعية: Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Antineoplastic Agents, Docetaxel, Pharmacology, Toxicology, Polymerase Chain Reaction, chemistry.chemical_compound, Pharmacokinetics, Tandem Mass Spectrometry, Internal medicine, medicine, Humans, Pharmacology (medical), CYP3A5, Peritoneal Neoplasms, Aged, DNA Primers, Ovarian Neoplasms, Base Sequence, business.industry, Middle Aged, medicine.disease, Carboplatin, chemistry, Pharmacogenetics, Pharmacogenomics, Midazolam, Female, Taxoids, Ovarian cancer, business, Chromatography, Liquid, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c82d225c22a5e8a17c47b3c162719b35
https://doi.org/10.1007/s00280-011-1609-9

المؤلفون: Michel Weïwer, Arlene S. Bridges, Paul L. DeAngelis, Jian Liu, Renpeng Liu, Miao Chen, Qisheng Zhang, Xianxuan Zhou, Robert J. Linhardt, Yongmei Xu

المصدر: Journal of Biological Chemistry. 285:34240-34249

مصطلحات موضوعية: Sulfotransferase, Glycan, Molecular Sequence Data, Disaccharide, Oligosaccharides, Glycobiology and Extracellular Matrices, Disaccharides, Protein Engineering, Polysaccharide, Biochemistry, Antithrombins, chemistry.chemical_compound, Sulfation, Polysaccharides, medicine, Humans, Molecular Biology, Chromatography, High Pressure Liquid, chemistry.chemical_classification, biology, Cell Biology, Heparan sulfate, Heparin, Oligosaccharide, Protein Structure, Tertiary, carbohydrates (lipids), Chemistry, Kinetics, Carbohydrate Sequence, chemistry, biology.protein, Heparitin Sulfate, Carbohydrate Epimerases, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c975193500b1371cb25cd8d2672eb8ce
https://doi.org/10.1074/jbc.m110.159152

المؤلفون: Gary M. Pollack, Thomas J. Raub, Jin Kyung Lee, Arlene S. Bridges, Kim L. R. Brouwer, Nita J. Patel, Koji Abe

المصدر: Drug Metabolism and Disposition. 37:1916-1921

مصطلحات موضوعية: Male, medicine.medical_specialty, Abcg2, Ratón, Blotting, Western, Pharmaceutical Science, In Vitro Techniques, Excretion, Mice, chemistry.chemical_compound, Glucuronides, Pharmacokinetics, Internal medicine, medicine, ATP Binding Cassette Transporter, Subfamily G, Member 2, Animals, Bile, Acetaminophen, Pharmacology, Sex Characteristics, biology, Sulfates, Chemistry, Body Weight, Transporter, Articles, Organ Size, Analgesics, Non-Narcotic, Mice, Inbred C57BL, Perfusion, Endocrinology, Liver, biology.protein, ATP-Binding Cassette Transporters, Female, Xenobiotic, Glucuronide, Algorithms, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19d84b649af6491225f5f741abe37dc
https://doi.org/10.1124/dmd.109.026815

المؤلفون: Thomas J. Raub, Rong Zhao, Steven C. Kasper, Gary M. Pollack, Arlene S. Bridges, James A. Bacon, Geri A. Sawada

المصدر: Drug Metabolism and Disposition. 37:1251-1258

مصطلحات موضوعية: Male, Abcg2, Pharmaceutical Science, Pharmacology, Blood–brain barrier, Mice, chemistry.chemical_compound, Osmotic Pressure, In vivo, medicine, ATP Binding Cassette Transporter, Subfamily G, Member 2, Animals, Drug Interactions, Chrysin, Transcellular, Protein Kinase Inhibitors, Dose-Response Relationship, Drug, biology, Brain, Biological Transport, Drug Synergism, Articles, In vitro, Neoplasm Proteins, Rats, Mice, Inbred C57BL, medicine.anatomical_structure, chemistry, Blood-Brain Barrier, Knockout mouse, Quinazolines, biology.protein, ATP-Binding Cassette Transporters, Efflux, Multidrug Resistance-Associated Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4b8e8e4c3643f515b9126a9bf5f9aa
https://doi.org/10.1124/dmd.108.025064

المؤلفون: Arlene S. Bridges, E. V. K. Suresh Kumar, Reto Brun, Stanislav A. Bakunov, Karl A. Werbovetz, Susan Jones, Donald A. Patrick, Kwasi A. Ohemeng, Todd Barszcz, Richard R. Tidwell, Tanja Wenzler, Svetlana M. Bakunova

المصدر: Journal of Medicinal Chemistry. 52:2016-2035

مصطلحات موضوعية: Trypanosoma brucei rhodesiense, medicine.drug_class, Plasmodium falciparum, Drug Resistance, Leishmania donovani, Melarsoprol, Trypanosoma brucei, Myoblasts, Antimalarials, Mice, Structure-Activity Relationship, Parasitic Sensitivity Tests, Trypanosomiasis, Cadaverine, parasitic diseases, Drug Discovery, medicine, Animals, Pentamidine, Trypanocidal agent, biology, Chemistry, Imidazoles, biology.organism_classification, Trypanocidal Agents, Rats, Biochemistry, Antiprotozoal, Molecular Medicine, Female, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89523a3ac4b43ffb24c86222c35eefb5
https://doi.org/10.1021/jm801547t

المؤلفون: Gary M. Pollack, Rong Zhao, J. Cory Kalvass, Arlene S. Bridges, Souzan B. Yanni

المصدر: Drug Metabolism and Disposition. 37:529-535

مصطلحات موضوعية: Pharmacology, Fexofenadine, biology, Chemistry, Central nervous system, Antagonist, Brain, Pharmaceutical Science, Articles, Blood–brain barrier, Mice, medicine.anatomical_structure, Pharmacokinetics, Blood-Brain Barrier, In vivo, medicine, biology.protein, Animals, Terfenadine, ATP Binding Cassette Transporter, Subfamily B, Member 1, P-glycoprotein, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23f2e4a10a1be37907952d49a1756a5
https://doi.org/10.1124/dmd.107.019893

المؤلفون: Robert D. Voyksner, Jennifer B. Dennison, Philip C. Smith, Arlene S. Bridges, Stephen D. Hall, Sally Kornbluth, Richard R. Tidwell, James Edwin Hall, Mary F. Paine, Judy Qiju Wu, Michael Zhuo Wang

المصدر: PROTEOMICS. 8:4186-4196

مصطلحات موضوعية: Adult, Male, Proteomics, Adolescent, CYP3A, Quantitative proteomics, Biochemistry, Mass Spectrometry, Hydroxylation, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Cytochrome P-450 CYP3A, Humans, Child, Molecular Biology, Aged, Chromatography, Sequence Homology, Amino Acid, biology, CYP3A4, Uncertainty, Cytochrome P450, Middle Aged, chemistry, Microsomes, Liver, biology.protein, Female, Quantitative analysis (chemistry)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701cdcb185132a07a96959d5f3776cfb
https://doi.org/10.1002/pmic.200800144

المؤلفون: Wei Yue, Kim L. R. Brouwer, Arlene S. Bridges, Koji Abe

المصدر: Journal of Pharmacology and Experimental Therapeutics. 326:983-990

مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Multidrug resistance-associated protein 2, Biology, Excretion, Endocrinology, Valsartan, Biliary tract, In vivo, Internal medicine, medicine, Molecular Medicine, Olmesartan, Pitavastatin, Pravastatin, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1dd7aec380b7cf6e89c2a9d1254d06f2
https://doi.org/10.1124/jpet.108.138073