المؤلفون: Ortuño-Costela, María del Carmen, Cerrada, Victoria, Moreno-Izquierdo, Ana, García-Consuegra, Inés, Laberthonnière, Camille, Delourme, Mégane, Garesse Alarcón, Rafael, Arenas, Joaquín, Fuster García, Carla, García García, Gema, Millán, José María, Magdinier, Frédérique, Gallardo, María Esther

المساهمون: UAM. Departamento de Bioquímica

مصطلحات موضوعية: CRISPR/Cas9, disease modelling, gene editing, iPSCs, isogenic control, McArdle disease, PYGM, read-through drugs, skeletal muscle differentiation, Medicina

وصف الملف: application/pdf

Relation: International Journal of Molecular Sciences; https://doi.org/10.3390/ijms232213964; Gobierno de España. PI15/00484; Gobierno de España. CP16/00046; Gobierno de España. PI17/02052; Gobierno de España. FPU16/03895; International Journal of Molecular Sciences 23.22 (2022): 13964; 1661-6596 (print); 1422-0067 (online); http://hdl.handle.net/10486/711310; 13964-1; 22; 13964-26; 23

الاتاحة: http://hdl.handle.net/10486/711310
https://doi.org/10.3390/ijms232213964

المؤلفون: Hampel, Harald, Vergallo, Andrea, Afshar, Mohammad, Akman-Anderson, Leyla, Arenas, Joaquín, Benda, Norbert, Batrla, Richard, Broich, Karl, Caraci, Filippo, Cuello, A, Emanuele, Enzo, Haberkamp, Marion, Kiddle, Steven, Lucía, Alejandro, Verdooner, Steven, Woodcock, Janet, Lista, Simone, Mapstone, Mark

المصدر: Dialogues in Clinical Neuroscience. 21(2)

مصطلحات موضوعية: Alzheimer’s disease, biomarker-drug codevelopment, blood-based biomarker, clinical trial, context of use, pathophysiology, precision medicine, predictive biomarker, systems biology, Alzheimer Disease, Biomarkers, Clinical Trials as Topic, Drug Development, Early Diagnosis, Eligibility Determination, Humans, Precision Medicine

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8hc1h876

المؤلفون: Cano Sanchez, Alejandro, Pastor Rodríguez, Alejandro, Escobar, Diego, Míguez Arenas, Joaquín, Sanjurjo Rivo, Manuel

المساهمون: Comunidad de Madrid

مصطلحات موضوعية: Uncertainty realism, Covariance realism, Space situational awareness, Covariance determination, Mahalanobis distance, Chi-square distribution, Cramer-von-mises, Kolmogorov-smirnov, Electrónica, Informática, Ingeniería Industrial, Telecomunicaciones

Relation: Comunidad de Madrid. IND2020/TIC-17539; AT-2022; Cano, A., Pastor, A. P., Escobar, D. A., Míguez, J., & Sanjurjo-Rivo, M. (2023). Covariance determination for improving uncertainty realism in orbit determination and propagation. Advances in Space Research, 72(7), 2759-2777.; http://hdl.handle.net/10016/38484; 2759; 2777; Advances in Space Research; 72; AR/0000033400

الاتاحة: http://hdl.handle.net/10016/38484

المؤلفون: Fernández de la Torre, Miguel, Fiuza-Luces, Carmen, Laine-Menéndez, Sara, Delmiro, Aitor, Arenas, Joaquín, Martín, Miguel Ángel, Lucia, Alejandro, Morán, María

Relation: International Journal of Molecular Sciences 24 (13): 10973 (2023); http://hdl.handle.net/10261/330412

الاتاحة: http://hdl.handle.net/10261/330412
https://doi.org/10.3390/ijms241310973

المؤلفون: Laine-Menéndez, Sara, Fernández-de la Torre, Miguel, Fiuza-Luces, Carmen, Delmiro, Aitor, Arenas, Joaquín, Martín, Miguel A., Boya, Patricia, Lucia, Alejandro, Morán, María

المساهمون: Instituto de Salud Carlos III, European Commission, Fiuza-Luces, Carmen, Delmiro, Aitor, Arenas, Joaquín, Boya, Patricia, Lucia, Alejandro, Morán, María

مصطلحات موضوعية: Autophagy, OXPHOS, Mitochondrial diseases, Harlequin, Heart, Skeletal muscle, Cerebellum, Brain

Relation: Publisher's version; https://doi.org/10.3390/antiox11030510; Sí; Antioxidants 11 (3) 510 (2022); http://hdl.handle.net/10261/290382

الاتاحة: http://hdl.handle.net/10261/290382
https://doi.org/10.3390/antiox11030510

المؤلفون: Hampel, Harald, Vergallo, Andrea, Afshar, Mohammad, Akman-Anderson, Leyla, Arenas, Joaquín, Benda, Norbert, Batrla, Richard, Broich, Karl, Caraci, Filippo, Cuello, A, Claudio, Emanuele, Enzo, Haberkamp, Marion, Kiddle, Steven, J, Lucía, Alejandro, Mapstone, Mark, Verdooner, Steven, R, Woodcock, Janet, Lista, Simone

المساهمون: Groupe de recherche clinique Alzheimer Precision Medicine (GRC 21 - APM), Sorbonne Université (SU), Institut du Cerveau = Paris Brain Institute (ICM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut de la Mémoire et de la Maladie d'Alzheimer CHU Pitié-Salpétriêre (IM2A), Université Pierre et Marie Curie - Paris 6 (UPMC)-CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), ANR-10-IAHU-0006,IHU-A-ICM,Institut de Neurosciences Translationnelles de Paris(2010)

المصدر: ISSN: 1294-8322.

مصطلحات موضوعية: Alzheimer's disease systems biology precision medicine blood-based biomarker context of use pathophysiology clinical trial predictive biomarker biomarker-drug codevelopment, Alzheimer's disease, systems biology, precision medicine, blood-based biomarker, context of use, pathophysiology, clinical trial, predictive biomarker, biomarker-drug codevelopment, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

Relation: info:eu-repo/semantics/altIdentifier/pmid/31636492; PUBMED: 31636492; PUBMEDCENTRAL: PMC6787542

الاتاحة: https://hal.sorbonne-universite.fr/hal-04496053
https://hal.sorbonne-universite.fr/hal-04496053v1/document
https://hal.sorbonne-universite.fr/hal-04496053v1/file/Blood-based%20systems%20biology%20biomarkers%20for%250Anext-generation%20clinical%20trials%20in%20Alzheimer%20s%20disease%20.pdf
https://doi.org/10.31887/dcns.2019.21.2/hhampel

المؤلفون: García Consuegra, Inés, Asensio Peña, Sara, Garrido Moraga, Rocío, Pinós, Tomàs, Domínguez González, Cristina, Santalla, Alfredo, Nogales Gadea, Gisela, Serrano Lorenzo, Pablo, Andreu, Antoni L., Arenas, Joaquín, Zugaza Gurruchaga, José Luis, Lucia, Alejandro, Martín, Miguel A.

مصطلحات موضوعية: PYGM, myophosphorylase, proteomics, McArdle disease, GSDV, iTRAQ, skeletal muscle, metabolic myopathy, protein biomarkers

وصف الملف: application/pdf

Relation: info:eu-repo/grantAgreement/MICINN/PI19/01313; info:eu-repo/grantAgreement/MICINN/PI17/02052; https://www.mdpi.com/1422-0067/23/9/4650/htm; International Journal of Molecular Sciences 23(9) : (2022) // Article ID 4650; http://hdl.handle.net/10810/56595

الاتاحة: http://hdl.handle.net/10810/56595
https://doi.org/10.3390/ijms23094650

المؤلفون: Villarreal Salazar, Mónica, Brull, Astrid, Nogales-Gadea, Gisela, Andreu, Antoni L., Martín Casanueva, Miguel Ángel, Arenas, Joaquín, Santalla Hernández, Alfredo, Lucía Mulas, Alejandro, Vissing, John, Krag, Thomas O., Pinós, Tomás

مصطلحات موضوعية: Enfermedad del almacenamiento de glucógeno tipo V, Metabolismo, Enfermedad cardiovascular, Genética

Relation: Villarreal-Salazar, M., Brull, A., Nogales-Gadea, G., Andreu, A. L., Martín, M. A., Arenas, J., Santalla, A., Lucía, A., Vissing, J., Krag, T. O., & Pinós, T. (2022). Preclinical Research in McArdle Disease: A Review of Research Models and Therapeutic Strategies. Genes, 13(1), 74. https://doi.org/10.3390/genes13010074; http://hdl.handle.net/11268/11043

الاتاحة: http://hdl.handle.net/11268/11043
https://doi.org/10.3390/genes13010074

المؤلفون: Cano, Alejandro, Pastor, Alejandro, Fernández, Sergio, Míguez Arenas, Joaquín, Sanjurjo Rivo, Manuel, Escobar, Diego

المساهمون: Comunidad de Madrid, Ministerio de Ciencia e Innovación (España)

مصطلحات موضوعية: Chi-square distribution, Covariance determination, Covariance realism, Mahalanobis distance, Space situational awareness, Uncertainty realism, Economía, Electrónica, Informática, Ingeniería Industrial, Telecomunicaciones

Relation: Comunidad de Madrid. IND2020/TIC-17539; Gobierno de España. PID2021-125159NB-I00; AT-2022; Cano, A. M., Pastor, A. P., Fernández, S., Míguez, J., Sanjurjo-Rivo, M., & Escobar, D. (2022). Improving Orbital Uncertainty Realism Through Covariance Determination in GEO. Journal of The Astronautical Sciences, 69(5), 1394-1420.; http://hdl.handle.net/10016/37167; https://doi.org/10.1007/s40295-022-00343-x; 1394; 1420; Journal of The Astronautical Sciences; 69; AR/0000031981

الاتاحة: http://hdl.handle.net/10016/37167
https://doi.org/10.1007/s40295-022-00343-x

المؤلفون: Santalla Hernández, Alfredo, Valenzuela, Pedro L., Rodríguez López, Carlos, Rodríguez Gómez, Irene, Nogales, Gisela, Pinós Figueras, Tomás, Arenas, Joaquín, Martín, Miguel Ángel, Santos Lozano, Alejandro, Morán, María, Fiuza Luces, Carmen, Ara Royo, Ignacio, Lucia, Alejandro

مصطلحات موضوعية: Myophosphorylase, Exercise is medicine, Glycogenosys type 5, Glycogen storage disease

وصف الملف: application/pdf

Relation: Medicine & Science in Sports & Exercise. 2022, 54,(3), 475-488; http://hdl.handle.net/10578/29633

الاتاحة: http://hdl.handle.net/10578/29633
https://doi.org/10.1249/MSS.0000000000002915

المؤلفون: Villarreal-Salazar, M., Santalla, A., Real-Martínez, A., Nogales-Gadea, G., Valenzuela, P. L., Fiuza-Luces, C., Andreu, Antoni L., Rodríguez-Aguilera, Juan Carlos, Martín, Miguel A., Arenas, Joaquín, Vissing, J., Lucía, A., Krag, T. O., Pinós, T.

المساهمون: Instituto de Salud Carlos III, European Commission, Consejo Nacional de Ciencia y Tecnología (México)

مصطلحات موضوعية: McArdle disease, Skeletal muscle, Glycogen, Aerobic capacity, Cytoskeleton and mitochondrial network

وصف الملف: application/pdf

Relation: Publisher's version; http://dx.doi.org/10.1016/j.molmet.2022.101648; Sí; e-issn: 2212-8778; Molecular Metabolism 66: 101648 (2022); http://hdl.handle.net/10261/296088

الاتاحة: http://hdl.handle.net/10261/296088
https://doi.org/10.1016/j.molmet.2022.101648

المؤلفون: Guerrero-Molina, María Paz, Morales-Conejo, Montserrat, Delmiro, Aitor, Morán, María, Domínguez-González, Cristina, Arranz-Canales, Elena, Ramos-González, Ana, Arenas, Joaquín, Martín, Miguel A., González de la Aleja, Jesús

المساهمون: Fundación Eugenio Rodríguez Pascual

المصدر: Journal of Neurology ; volume 269, issue 6, page 3238-3248 ; ISSN 0340-5354 1432-1459

الاتاحة: http://dx.doi.org/10.1007/s00415-021-10942-7
https://link.springer.com/content/pdf/10.1007/s00415-021-10942-7.pdf
https://link.springer.com/article/10.1007/s00415-021-10942-7/fulltext.html

المؤلفون: Fernández-Vizarra, Erika, López-Calcerrada, Sandra, Sierra-Magro, Ana, Pérez-Pérez, Rafael, Formosa, Luke E., Hock, Daniella H., Illescas, María, Peñas, Ana, Brischigliaro, Michele, Ding, Shujing, Fearnley, Ian M., Tzoulis, Charalampos, Pitceathly, Robert D.S., Arenas, Joaquín, Martín, Miguel A., Stroud, David A., Zeviani, Massimo, Ryan, Michael T., Ugalde, Cristina

المصدر: Cell Metabolism ; volume 34, issue 11, page 1792-1808.e6 ; ISSN 1550-4131

الاتاحة: http://dx.doi.org/10.1016/j.cmet.2022.09.005
https://api.elsevier.com/content/article/PII:S1550413122003953?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1550413122003953?httpAccept=text/plain

المؤلفون: Domínguez-González, Cristina, Hernández-Voth, Ana, de Fuenmayor-Fernández de la Hoz, Carlos Pablo, Guerrero, Laura Bermejo, Morís, Germán, García-García, Jorge, Muelas, Nuria, León Hernández, Juan Carlos, Rabasa, Maria, Lora, David, Blázquez, Alberto, Arenas, Joaquín, Martin, Miguel Ángel

المصدر: Neuromuscular Disorders ; volume 32, issue 9, page 728-735 ; ISSN 0960-8966

الاتاحة: http://dx.doi.org/10.1016/j.nmd.2022.07.399
https://api.elsevier.com/content/article/PII:S0960896622006010?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0960896622006010?httpAccept=text/plain

المؤلفون: García-López, Marta, Jiménez-Vicente, Lydia, González-Jabardo, Raquel, Dorado, Helena, Gómez-Manjón, Irene, Martín, Miguel Ángel, Ayuso, Carmen, Arenas, Joaquín, Gallardo, María Esther

المصدر: International Journal of Molecular Sciences; Jul2024, Vol. 25 Issue 13, p7240, 27p

مصطلحات موضوعية: RETINAL ganglion cells, RESPIRATION, MITOCHONDRIAL DNA, MITOCHONDRIAL dynamics, ATROPHY, SMALL molecules, CELL survival

المؤلفون: Ceballos, Francisco, Serrano-Lorenzo, Pablo, Bermejo-Guerrero, Laura, Blázquez, Alberto, Quesada-Espinosa, Juan F., Amigo, Jorge, Minguez, Pablo, Ayuso, Carmen, García-Arumí, Elena, Muelas, Nuria, Jaijo, Teresa, Nascimento, Andres, Galán-Rodriguez, Beatriz, Paradas, Carmen, Arenas, Joaquín, Carracedo, Angel, Martí, Ramon, Martín, Miguel A., Domínguez-González, Cristina

المصدر: Neurology Genetics ; volume 10, issue 2 ; ISSN 2376-7839

الاتاحة: http://dx.doi.org/10.1212/nxg.0000000000200138
https://www.neurology.org/doi/pdfdirect/10.1212/NXG.0000000000200138

المؤلفون: Serrano Lorenzo, Pablo, Coya, Olga N., López Jiménez, Ana, Blázquez Encinar, Alberto, Delmiro, Aitor, Lucía Mulas, Alejandro, Arenas, Joaquín, Martín, Miguel A., Santos Lozano, Alejandro, Miguel Reyes, Montserrat de

مصطلحات موضوعية: Infecciones por coronavirus, Membrana celular, Medicina clínica, Enfermedad transmisible

Relation: Serrano Lorenzo, P., Coya, O. N., López-Jiménez, A., Blázquez, A., Delmiro, A., Lucía, A., Arenas, J., Martín, M. A., Santos Lozano, A., Cueto Felgueroso, C., Fernández-del Pozo, A., & Miguel-Reyes, M. (2021). Plasma LDH: A specific biomarker for lung affectation in COVID-19? Practical Laboratory Medicine, 25, e00226. https://doi.org/10.1016/j.plabm.2021.e00226; http://hdl.handle.net/11268/10081

الاتاحة: http://hdl.handle.net/11268/10081
https://doi.org/10.1016/j.plabm.2021.e00226

المؤلفون: Eguiburu Jaime, José L., Delmiro, Aitor, Lalueza, Antonio, Valenzuela Ruiz, Pedro Luis, Aguado, José M., Lumbreras Bermejo, Carlos, Arenas, Joaquín, Martín, Miguel Ángel, Lucía Mulas, Alejandro, López Jiménez, Elena A.

مصطلحات موضوعية: Insuficiencia respiratoria, Tirosina, Infecciones por coronavirus, Medicina deportiva

Relation: Eguiburu-Jaime, J. L., Delmiro, A., Lalueza, A., Valenzuela, P. L., Aguado, J. M., Lumbreras, C., Arenas, J., Martín, M. A., Lucia, A., & López-Jiménez, E. A. (2021). Soluble fms-like tyrosine kinase-1: a potential early predictor of respiratory failure in COVID-19 patients. Clinical Chemistry and Laboratory Medicine, 59(7), e289–e292. https://doi.org/10.1515/cclm-2021-0126; http://hdl.handle.net/11268/10063

الاتاحة: http://hdl.handle.net/11268/10063
https://doi.org/10.1515/cclm-2021-0126

المؤلفون: Míguez Arenas, Joaquín, Elvira Arregui, Víctor, Djuric, Petar

المساهمون: Springer, Agencia Estatal de Investigación (España)

مصطلحات موضوعية: Particle filtering, Sequential Monte Carlo, Predictive distributions, Convergence analysis, Adaptive complexity, Ingeniería Industrial

Relation: Gobierno de España. RTI2018-099655-B-I00; AT-2021; Elvira, V., Miguez, J., & Djurić, P. M. (2021). On the performance of particle filters with adaptive number of particles. En Statistics and Computing, 31(6) , pp. 1-18; http://hdl.handle.net/10016/34394; https://doi.org/10.1007/s11222-021-10056-0; 18; STATISTICS AND COMPUTING; 31; AR/0000030338

الاتاحة: http://hdl.handle.net/10016/34394
https://doi.org/10.1007/s11222-021-10056-0

المؤلفون: Martino, Luca, Llorente Fernández, Fernando, Curbelo Benitez, Ernesto Angel, López Santiago, Javier, Míguez Arenas, Joaquín

المساهمون: Comunidad de Madrid, Ministerio de Ciencia e Innovación (España)

مصطلحات موضوعية: Bayesian inference, Importance sampling, MCMC, Inversion problems, Estadística, Telecomunicaciones

Relation: Comunidad de Madrid. Y2018/TCS-4705; Gobierno de España. RTI2018-099655-B-I00; Gobierno de España. PID2019-105032GB-I00; Martino, L., Llorente, F., Curbelo, E., López-Santiago, J. & Míguez, J. (2021). Automatic Tempered Posterior Distributions for Bayesian Inversion Problems. Mathematics, 9(7), 784.; http://hdl.handle.net/10016/33483; https://doi.org/10.3390/math9070784; 784; Mathematics; AR/0000028411

الاتاحة: http://hdl.handle.net/10016/33483
https://doi.org/10.3390/math9070784