المؤلفون: Emily C. Cherney (8904614), Liping Zhang (177396), Weiwei Guo (117411), Audris Huang (1436374), David Williams (229939), Steven Seitz (10980140), Weifang Shan (1371309), Xiao Zhu (257280), Johnni Gullo-Brown (2387257), Derrick Maley (10048683), Tai-an Lin (10218930), John T. Hunt (1601446), Christine Huang (743871), Zheng Yang (264955), Celia J. D’Arienzo (1429867), Lorell N. Discenza (9406835), Asoka Ranasinghe (1601449), Mary F. Grubb (4230607), Sarah C. Traeger (1622287), Xin Li (51274), Kathy A. Johnston (1372455), Lisa Kopcho (5941772), Mark Fereshteh (6508499), Kimberly A. Foster (2649784), Kevin Stefanski (1551436), Diane Delpy (10048689), Gopal Dhar (8394876), Aravind Anandam (8394879), Sandeep Mahankali (10218936), Shweta Padmanabhan (4067707), Prabhakar Rajanna (8779820), Venkata Murali (10218939), T. Thanga Mariappan (8958191), Shabeerali Pattasseri (10980143), Roshan Y. Nimje (2222026), Zhenqiu Hong (1745164), James Kempson (1665415), Richard Rampulla (1601455), Arvind Mathur (144120), Anuradha Gupta (1551397), Robert Borzilleri (2102530), Gregory Vite (2853350), Aaron Balog (1371318)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, Cancer, Space Science, Chemical Sciences not elsewhere classified, Conformational-Analysis-Guided Disc., metastatic melanoma, mouse xenograft model, cell carcinoma, novel heme-displacing IDO 1 inhibitors, IDO 1 inhibitor, molecules linrodostat, pharmacodynamic activity, oxidative metabolism, fluorine incorporation, compound 29, BMS -986242, quinoline

Relation: https://figshare.com/articles/journal_contribution/Conformational-Analysis-Guided_Discovery_of_2_3-Disubstituted_Pyridine_IDO1_Inhibitors/14791424

الاتاحة: https://doi.org/10.1021/acsmedchemlett.1c00236.s001

المؤلفون: Liping Zhang (177396), Emily C. Cherney (8904614), Xiao Zhu (257280), Tai-an Lin (10218930), Johnni Gullo-Brown (2387257), Derrick Maley (10048683), Kathy Johnston-Allegretto (10218933), Lisa Kopcho (5941772), Mark Fereshteh (6508499), Christine Huang (743871), Xin Li (51274), Sarah C. Traeger (1622287), Gopal Dhar (8394876), Aravind Anandam (8394879), Sandeep Mahankali (10218936), Shweta Padmanabhan (4067707), Prabhakar Rajanna (8779820), Venkata Murali (10218939), Thanga Mariappan (10218942), Robert Borzilleri (2102530), Gregory Vite (2853350), John T. Hunt (1601446), Aaron Balog (1371318)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Hematology, Virology, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, phase III, metastatic melanoma, Potent Inhibitors, cell carcinoma, variety, BMS, imidazopyridine-containing IDO 1 in., IDO 1 inhibitors, IDO 1 inhibitor, small-molecule immunotherapy, heterocyclic isosteres, Indoleamine, IDO 1-selective inhibitor

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_Imidazopyridines_as_Potent_Inhibitors_of_Indoleamine_2_3-Dioxygenase_1_for_Cancer_Immunotherapy/14141796

الاتاحة: https://doi.org/10.1021/acsmedchemlett.1c00014.s001

المؤلفون: Mark Fereshteh, Xiao Zhu, Tai-An Lin, Prabhakar Rajanna, Cherney Emily Charlotte, Aravind Anandam, Xin Li, Derrick Maley, Liping Zhang, Gopal Dhar, Aaron Balog, Robert M. Borzilleri, Johnni Gullo-Brown, T. Thanga Mariappan, Kathy Johnston-Allegretto, Christine Huang, Venkata Murali, John T. Hunt, Sandeep Mahankali, Gregory D. Vite, Lisa M. Kopcho, Shweta Padmanabhan, Sarah C. Traeger

المصدر: ACS Med Chem Lett

مصطلحات موضوعية: Metastatic melanoma, 010405 organic chemistry, business.industry, medicine.medical_treatment, Organic Chemistry, Phases of clinical research, Immunotherapy, medicine.disease, 01 natural sciences, Biochemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Cancer immunotherapy, Renal cell carcinoma, Drug Discovery, medicine, Cancer research, business, Indoleamine 2,3-dioxygenase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69bf6be584624b416a38e3f63d582b0
https://doi.org/10.1021/acsmedchemlett.1c00014

المؤلفون: Jennifer Brown, Karen E. Parrish, Andrew J. Tebben, Jonathan Lippy, Kamalavenkatesh Palanisamy, Todd Kinsella, Chetan Padmakar Darne, Vinay K. Holenarsipur, Anwar Murtaza, Muthalagu Vetrichelvan, Chunhong Yan, Karen Augustine-Rauch, Max Ruzanov, Mark Fereshteh, Upender Velaparthi, Gopal Dhar, Gregory D. Vite, Peiying Liu, Steven Sheriff, Jayakumar Sankara Warrier, Aravind Anandam, Marina Gelman, Arvind Mathur, Barri Wautlet, Robert M. Borzilleri, Hasibur Rahaman, Zheng Yang, Anuradha Gupta, Arun Kumar Gupta, Rajinder Singh, Joseph Fargnoli, Jesse Swanson

المصدر: ACS Med Chem Lett

مصطلحات موضوعية: biology, 010405 organic chemistry, business.industry, Organic Chemistry, Pharmacology, 01 natural sciences, Biochemistry, 0104 chemical sciences, Bioavailability, 010404 medicinal & biomolecular chemistry, Regimen, Pharmacokinetics, In vivo, Drug Discovery, biology.protein, Medicine, Potency, Kinome, Dosing, Antibody, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c0a6b7db9a564a606d22c0c365bdb7
https://doi.org/10.1021/acsmedchemlett.9b00552

المؤلفون: Lisa M. Kopcho, Johnni Gullo-Brown, Shweta Padmanabhan, Pattasseri Shabeerali, Arvind Mathur, Prabhakar Rajanna, Lorell Discenza, Liping Zhang, Zhenqiu Hong, Sarah C. Traeger, Zheng Yang, Cherney Emily Charlotte, Richard Rampulla, David K. Williams, Gopal Dhar, Kimberly A. Foster, James Kempson, Derrick Maley, Mary F. Grubb, Xiao Zhu, Xin Li, Weifang Shan, Robert M. Borzilleri, Diane Delpy, Kevin Stefanski, T. Thanga Mariappan, Gregory D. Vite, Kathy A. Johnston, Audris Huang, Asoka Ranasinghe, Mark Fereshteh, Aravind Anandam, Steven P. Seitz, John T. Hunt, Aaron Balog, Celia D’Arienzo, Anuradha Gupta, Tai-An Lin, Roshan Y. Nimje, Weiwei Guo, Christine Huang, Venkata Murali, Sandeep Mahankali

المصدر: ACS Med Chem Lett

مصطلحات موضوعية: chemistry.chemical_compound, Oxidative metabolism, chemistry, Metastatic melanoma, Mouse xenograft, Organic Chemistry, Drug Discovery, Pyridine, Quinoline, Biochemistry, Combinatorial chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f0d7f8a891846e7ad07844b139d549
https://europepmc.org/articles/PMC8274105/

المؤلفون: Natalie Bezman, Michelle Kinder, Natalie Hutnick, Alan J. Korman, Gopal Dhar, Robert F. Graziano, Lavanya Kovvuri, Dorie Capaldi, Amy Jhatakia, Mark Mendonca, Vivek Surse, Aravind Anandam, Swagatam Ray, Edward W. Thompson, Darlene Pizutti, Mattson Bethany Kay, Elizabeth Saravia, Archana Devi

المصدر: Cancer Research. 78:1727-1727

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.diagnostic_test, business.industry, medicine.drug_class, Daratumumab, CD38, medicine.disease, Monoclonal antibody, In vitro, Flow cytometry, 03 medical and health sciences, 030104 developmental biology, Oncology, Cancer research, medicine, Nivolumab, Lung cancer, business, CD8

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0cf840b86a0b0d4d9feac8f004dbfca2
https://doi.org/10.1158/1538-7445.am2018-1727

المؤلفون: Udupa Nayanabhirama, Karthik Arumugam, Satish Rao Bola Sadashiva, Prashant B Musmade, Aravind Anandam, Gopal V. Shavi, Sunil Kumar Mandala Rayabandla, Krishnamoorthy Bhat, Kiran Aithal

المصدر: Drug delivery. 17(3)

مصطلحات موضوعية: Materials science, Chemistry, Pharmaceutical, Drug Compounding, Melanoma, Experimental, Pharmaceutical Science, Pharmacology, Microsphere, Chitosan, chemistry.chemical_compound, Mice, Pharmacokinetics, medicine, Animals, Particle Size, Chromatography, High Pressure Liquid, Calorimetry, Differential Scanning, Melanoma, General Medicine, Plumbagin, medicine.disease, Antineoplastic Agents, Phytogenic, In vitro, Microspheres, Blood Cell Count, Mice, Inbred C57BL, Cross-Linking Reagents, chemistry, Glutaral, Pharmacodynamics, Delayed-Action Preparations, Microscopy, Electron, Scanning, Pharmaceutics, Spectrophotometry, Ultraviolet, Half-Life, Naphthoquinones

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a317ddd42345ca2a9cb42529886cec1
https://pubmed.ncbi.nlm.nih.gov/20100068