المؤلفون: Sérgio M. Marques, Petr Kouba, Anthony Legrand, Jiri Sedlar, Lucas Disson, Joan Planas-Iglesias, Zainab Sanusi, Antonin Kunka, Jiri Damborsky, Tomas Pajdla, Zbynek Prokop, Stanislav Mazurenko, Josef Sivic, David Bednar

المصدر: JACS Au, Vol 4, Iss 6, Pp 2228-2245 (2024)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2691-3704

URL الوصول: https://doaj.org/article/7910a03b1e3c466486a988ae2dbf68c8

المؤلفون: Michal Nemergut, Sérgio M. Marques, Lukas Uhrik, Tereza Vanova, Marketa Nezvedova, Darshak Chandulal Gadara, Durga Jha, Jan Tulis, Veronika Novakova, Joan Planas-Iglesias, Antonin Kunka, Anthony Legrand, Hana Hribkova, Veronika Pospisilova, Jiri Sedmik, Jan Raska, Zbynek Prokop, Jiri Damborsky, Dasa Bohaciakova, Zdenek Spacil, Lenka Hernychova, David Bednar, Martin Marek

المصدر: Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-25 (2023)

مصطلحات موضوعية: Apolipoprotein E, Alzheimer’s disease, Neurodegeneration, Aggregation, Cerebral organoids, Molecular dynamics, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1750-1326

URL الوصول: https://doaj.org/article/3de537d320b7425ab0b3c676809f76bd

المؤلفون: Klara Markova (6639851), Antonin Kunka (5745425), Klaudia Chmelova (11539195), Martin Havlasek (11539198), Petra Babkova (3205713), Sérgio M. Marques (2360983), Michal Vasina (6938837), Joan Planas-Iglesias (1452142), Radka Chaloupkova (492929), David Bednar (821277), Zbynek Prokop (821281), Jiri Damborsky (1322766), Martin Marek (463593)

مصطلحات موضوعية: Biophysics, Biochemistry, Evolutionary Biology, Virology, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, Information Systems not elsewhere classified, unfolding experiments showed, stabilizing mutations might, nascent polypeptide follows, local energy minima, linking mass spectrometry, increased catalytic rate, global energy minimum, force field calculations, establish secondary interfaces, crystallographic structures revealed, activate cryptic hinge, 5 ° c, 23 ° c, hydrolase enzyme (<, like energy landscape, swapped intermediates trapped, stabilize native proteins, catalytically enhanced domain, computational enzyme stabilization, computational stabilization, enzyme depends, like monomers

Relation: https://figshare.com/articles/journal_contribution/Computational_Enzyme_Stabilization_Can_Affect_Folding_Energy_Landscapes_and_Lead_to_Catalytically_Enhanced_Domain-Swapped_Dimers/16775737

الاتاحة: https://doi.org/10.1021/acscatal.1c03343.s001

المؤلفون: Michal Vasina, Pavel Vanacek, Jiri Hon, David Kovar, Hana Faldynova, Antonin Kunka, Tomas Buryska, Christoffel P.S. Badenhorst, Stanislav Mazurenko, David Bednar, Stavros Stavrakis, Uwe T. Bornscheuer, Andrew deMello, Jiri Damborsky, Zbynek Prokop

المصدر: Chem Catalysis. 2:2704-2725

مصطلحات موضوعية: Chemistry (miscellaneous), Organic Chemistry, Physical and Theoretical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3c2c5970e627d7ff12bfe29b45620d47
https://doi.org/10.1016/j.checat.2022.09.011

المؤلفون: Pavel Vanacek (10015247), Michal Vasina (9247186), Jiri Hon (9457106), David Kovar (10015250), Hana Faldynova (10015245), Antonin Kunka (9457109), Tomas Buryska (10015253), Christoffel P. S. Badenhorst (10015254), Stanislav Mazurenko (9711750), David Bednar (9247193), Uwe T. Bornscheuer (9247197), Jiri Damborsky (9242771), Zbynek Prokop (9705845)

مصطلحات موضوعية: Biocatalysis, Enzyme Discovery, database maning, EnzymeMiner, microfluidics, microanalytics, bioinformatics, haloalkane dehalogenase

Relation: https://figshare.com/articles/preprint/Functional_Annotation_of_an_Enzyme_Family_by_Integrated_Strategy_Combining_Bioinformatics_with_Microanalytical_and_Microfluidic_Technologies/13621517

الاتاحة: https://doi.org/10.26434/chemrxiv.13621517.v1

المؤلفون: Klara Markova (10027446), Antonin Kunka (9457109), Klaudia Chmelova (10027449), Martin Havlasek (10027451), Petra Babkova (10027452), Sérgio M. Marques (9584429), Michal Vasina (9247186), Joan Planas-Iglesias (9247181), Radka Chaloupková (9247191), David Bednar (9247193), Zbynek Prokop (9705845), Jiri Damborsky (9242771), Martin Marek (6558650)

مصطلحات موضوعية: Biocatalysis, protein folding, protein design, α/β-hydrolase, haloalkane dehalogenase, domain-swapping, dimerization, energy landscape, oligomerization

Relation: https://figshare.com/articles/preprint/Computational_Protein_Stabilization_Can_Affect_Folding_Energy_Landscapes_and_Lead_to_Domain-Swapped_Dimers/13634021

الاتاحة: https://doi.org/10.26434/chemrxiv.13634021.v1

المؤلفون: Petra Babková, Martin Marek, Jiri Damborsky, Klaudia Chmelova, Joan Planas-Iglesias, K. Markova, Sérgio M. Marques, Antonin Kunka, David Bednar, Michal Vasina, Martin Havlasek, Zbynek Prokop, Radka Chaloupková

المصدر: ACS Catalysis. 11:12864-12885

مصطلحات موضوعية: Physics, chemistry.chemical_classification, 0303 health sciences, 030302 biochemistry & molecular biology, General Chemistry, Catalysis, Domain (software engineering), Folding (chemistry), 03 medical and health sciences, Lead (geology), Enzyme, chemistry, Biophysics, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::99ef53e71cbeefe6b5a1ed117b1a8c46
https://doi.org/10.1021/acscatal.1c03343

المؤلفون: Jiri Hon, Tomáš Martínek, David Bednar, Jiri Damborsky, Antonin Kunka, Martin Marusiak, Jaroslav Zendulka

المصدر: Bioinformatics

مصطلحات موضوعية: Statistics and Probability, Prioritization, AcademicSubjects/SCI01060, Computer science, SOLUBILITY, WEBSERVER, TOPOLOGY, ACCURATE, Sequence alignment, Computational biology, medicine.disease_cause, Biochemistry, Protein expression, 03 medical and health sciences, medicine, Solubility, Molecular Biology, Escherichia coli, 030304 developmental biology, 0303 health sciences, Training set, Chemistry, 030302 biochemistry & molecular biology, Biological activity, Original Papers, Computer Science Applications, Computational Mathematics, Computational Theory and Mathematics, Test set, Gradient boosting, Protein solubility, Sequence Analysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82526e9ab2df70292056202a537b7c39
https://doi.org/10.1093/bioinformatics/btaa1102

المؤلفون: Antonin Kunka, David Lacko, Jan Stourac, Jiri Damborsky, Zbynek Prokop, Stanislav Mazurenko

المصدر: Nucleic acids research

مصطلحات موضوعية: FLUORESCENCE, CALORIMETRY, RESOLUTION, STATE, Genetics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61799b9ae49a6aa8a204779b6849bac4
https://pubmed.ncbi.nlm.nih.gov/35580052

المؤلفون: Michal Vasina, Pavel Vanacek, Jiri Hon, David Kovar, Hana Faldynova, Antonin Kunka, Tomas Buryska, Christoffel P. S. Badenhorst, Stanislav Mazurenko, David Bednar, Stavros Stavrakis, Uwe T. Bornscheuer, Andrew de Mello, Jiri Damborsky, Zbynek Prokop

مصطلحات موضوعية: History, Polymers and Plastics, Business and International Management, Industrial and Manufacturing Engineering

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f0a8d7c75931429cab147cb94d50433
https://doi.org/10.26434/chemrxiv-2022-zdrw5-v2

المؤلفون: Antonin Kunka, David Kovar, Zbynek Prokop, Tomas Buryska, Andrew J. deMello, Pavel Vanacek, Jiri Damborsky, Christoffer Badenhorst, Hanka Faldynova, David Bednar, Michal Vasina, Stavros Stavros, Jiri Hon, Uwe T. Bornscheuer, Stanislav Mazurenko

مصطلحات موضوعية: Chemistry, Microfluidics, Computational biology, Enzyme family, Throughput (business), Characterization (materials science)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6e491c317c6306c64d74eda064509aa9
https://doi.org/10.21203/rs.3.rs-1027271/v1

المؤلفون: Martin Marek, Havlasek M, Zbyněk Prokop, Jiri Damborsky, David Bednar, K. Markova, Antonin Kunka, Joan Planas-Iglesias, Michal Vasina, Radka Chaloupková, Klaudia Chmelova, Petra Babková, Sérgio M. Marques

مصطلحات موضوعية: Folding (chemistry), chemistry.chemical_compound, Monomer, chemistry, Small-angle X-ray scattering, Protein design, Biophysics, Energy landscape, Protein folding, Protein stabilization, Force field (chemistry)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17def03799b6b9c822a62c7f7c19eca0
https://doi.org/10.26434/chemrxiv.13634021

المؤلفون: Lukas Balek, Lívia Eiselleová, Veronika Stepankova, Pavel Krejci, Tereza Vanova, Pavel Vanacek, Stanislav Mazurenko, Jan Brezovsky, Zbynek Prokop, Karolina Zoufalova, David Bednar, Petr Dvorak, Pavel Dvorak, Michaela Bosakova, Antonin Kunka, Zaneta Konecna, Jiri Damborsky, Radka Chaloupková, Eva Sebestova

المصدر: Biotechnology and Bioengineering. 115:850-862

مصطلحات موضوعية: 0301 basic medicine, Protein Folding, Computer science, In silico, Bioengineering, Computational biology, Protein Engineering, Fibroblast growth factor, Applied Microbiology and Biotechnology, 03 medical and health sciences, 0302 clinical medicine, Protein stability, Animals, Humans, Point Mutation, Computational design, Computer Simulation, Amino Acid Sequence, Embryonic Stem Cells, Protein Stability, Mechanism (biology), business.industry, Protein engineering, Biotechnology, 030104 developmental biology, 030220 oncology & carcinogenesis, Computer-Aided Design, Fibroblast Growth Factor 2, Directed Molecular Evolution, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359f80cbfcb3749d783bddec203f2d89
https://doi.org/10.1002/bit.26531

المؤلفون: Christopher M. Johnson, Koen Beerens, Stanislav Mazurenko, Antonin Kunka, Zbynek Prokop, Jiri Damborsky

المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, 030103 biophysics, Protein design, lcsh:Medicine, Calorimetry, Chick Embryo, Protein Engineering, Heat capacity, Article, 03 medical and health sciences, Differential scanning calorimetry, Animals, lcsh:Science, Protein Unfolding, Multidisciplinary, Chemistry, lcsh:R, Protein engineering, Kinetics, 030104 developmental biology, Curve fitting, Biophysics, Unfolded protein response, Protein folding, Muramidase, lcsh:Q

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::325ba97775dbe671d86b06011935475a
http://link.springer.com/article/10.1038/s41598-017-16360-y

المؤلفون: Michael Kotik, Antonin Kunka, Jiri Damborsky, Pavel Vanacek, Zbynek Prokop

المصدر: Applied Microbiology and Biotechnology. 101:6385-6397

مصطلحات موضوعية: 0301 basic medicine, Subfamily, Hydrolases, Stereochemistry, 030106 microbiology, Biology, Polymerase Chain Reaction, Applied Microbiology and Biotechnology, Substrate Specificity, 03 medical and health sciences, Bacterial Proteins, Groundwater, Gene, Phylogeny, DNA Primers, Thermostability, chemistry.chemical_classification, Bacteria, Protein Stability, Temperature, Substrate (chemistry), General Medicine, Hydrogen-Ion Concentration, Amplicon, 030104 developmental biology, Enzyme, Biochemistry, chemistry, Biocatalysis, Metagenome, Protein quaternary structure, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4121a431ecf85f4d21cac8629d0b1eea
https://doi.org/10.1007/s00253-017-8393-3

المؤلفون: Martin Marek, Klara Markova, Antonin Kunka, Klaudia Chmelova, Martin Havlasek, Petra Babkova, Sérgio M. Marques, Michal Vasina, Joan Iglesias Planas, Radka Chaloupkova, David Bednar, Zbynek Prokop, Jiri Damborsky

المصدر: Acta Crystallographica Section A Foundations and Advances. 77:C340-C340

مصطلحات موضوعية: Inorganic Chemistry, Structural Biology, General Materials Science, Physical and Theoretical Chemistry, Condensed Matter Physics, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::31d57d9620955fd0931818a8ce8d98b7
https://doi.org/10.1107/s0108767321093454

المؤلفون: Antonin, Kunka, Jiri, Damborsky, Zbynek, Prokop

المصدر: Methods in enzymology. 605

مصطلحات موضوعية: Aldehydes, Aquatic Organisms, Halogens, Hydrolases, Alkanes, Biocatalysis, Green Chemistry Technology, Biotechnology, Enzyme Assays, Substrate Specificity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::13c2847cfb5809dc960d05d1ae78910c
https://pubmed.ncbi.nlm.nih.gov/29909825

المؤلفون: Azad Farzadfard, Antonin Kunka, Thomas O. Mason, Jacob A. Larsen, Rasmus K. Norrild, Elisa T. Dominguez, Soumik Ray, Alexander Buell

الاتاحة: http://dx.doi.org/10.1039/d3sc05371g/v2/response1

المؤلفون: Jiri Damborsky, Zbynek Prokop, Antonin Kunka

المصدر: Methods in Enzymology

مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Haloalkane, biology, Chemistry, In silico, biology.organism_classification, 03 medical and health sciences, 030104 developmental biology, Biochemistry, Substrate specificity, High activity, Identification (biology), Enzyme family, Bacteria, Archaea

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df2de290d8524ac84d51c19d8d799b4
https://doi.org/10.1016/bs.mie.2018.03.005

المؤلفون: Pavel Vanacek, Jiri Damborsky, Pavel Dvorak, David Bednar, Lívia Eiselleová, Eva Sebestova, Zbynek Prokop, Antonin Kunka, Daniel Horák, Pavel Krejci, Radka Chaloupková, Veronika Stepankova, Zaneta Konecna, Petr Dvorak, Lukas Balek, Stanislav Mazurenko, Jan Brezovsky, Michaela Bosakova

مصطلحات موضوعية: 0303 health sciences, 03 medical and health sciences, 0302 clinical medicine, In vivo, 030220 oncology & carcinogenesis, Protein engineering, Biology, Fibroblast growth factor, In vitro, 030304 developmental biology, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1934f1394550038597e5eb514081294
https://doi.org/10.1101/100636