المؤلفون: Natalia L. Klyachko, Matthew J. Haney, Anton V. Lopukhov, Irina M. Le-Deygen

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)

مصطلحات موضوعية: Cancer, EVs, Gene delivery, Multivalent cationic lipid, Transfection, Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/f7622b59ef5e4a1c84f9e241843437dc

المؤلفون: Svetlana Yu. Maklakova, Anton V. Lopukhov, Alexandr D. Khudyakov, Sergey V. Kovalev, Maria P. Mazhuga, Olga E. Chepikova, Andrey A. Zamyatnin, Alexander G. Majouga, Natalia L. Klyachko, Elena K. Beloglazkina

المصدر: RSC Medicinal Chemistry. 14:56-64

مصطلحات موضوعية: Pharmacology, Organic Chemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d97596c09ca6223ee6a8cecdd3856c24
https://doi.org/10.1039/d2md00119e

المؤلفون: Ya. A. Ivanenkov, Sergey V. Kovalev, Elena K. Beloglazkina, E. Yu. Yamansarov, Natalia L. Klyachko, Nikolai V. Zyk, Rostislav A Petrov, Dmitry A. Skvortsov, Sergei A Evteev, Anton V Lopukhov, Alexander G. Majouga

المصدر: Russian Chemical Bulletin. 68:2331-2338

مصطلحات موضوعية: Betulin, 010405 organic chemistry, Chemistry, Stereochemistry, In silico, General Chemistry, 010402 general chemistry, 01 natural sciences, In vitro, 0104 chemical sciences, Terpene, chemistry.chemical_compound, Triterpenoid, Betulinic acid, Surface plasmon resonance spectroscopy, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8e6f153ec852abc74a9c23a071b5973f
https://doi.org/10.1007/s11172-019-2707-9

المؤلفون: Dmitry O Shkil, Petr V. Gorelkin, Alexander N. Lobov, V.A. Naumenko, Alexander Erofeev, Olga Y. Burenina, Yan A. Ivanenkov, Emil Yu. Yamansarov, Roman Akasov, Dmitry A. Skvortsov, Natalia L. Klyachko, Elena K. Beloglazkina, Sergey V. Kovalev, Alexander G. Majouga, Oxana Ryabaya, Elena V Lopatukhina, Ekaterina N Pavlova, Alexander Vaneev, Sergei A Evteev, Anton V Lopukhov

المصدر: Bioconjugate chemistry. 32(4)

مصطلحات موضوعية: Acetylgalactosamine, Carcinoma, Hepatocellular, Glycoconjugate, media_common.quotation_subject, Biomedical Engineering, Pharmaceutical Science, Bioengineering, Antineoplastic Agents, 02 engineering and technology, Asialoglycoprotein Receptor, 01 natural sciences, chemistry.chemical_compound, Drug Delivery Systems, In vivo, Cell Line, Tumor, Drug Discovery, Humans, Cytotoxicity, Internalization, media_common, Fluorescent Dyes, Pharmacology, chemistry.chemical_classification, Betulin, 010405 organic chemistry, Organic Chemistry, Liver Neoplasms, Surface Plasmon Resonance, 021001 nanoscience & nanotechnology, In vitro, Triterpenes, 0104 chemical sciences, Molecular Docking Simulation, Biochemistry, chemistry, Asialoglycoprotein receptor, Drug Screening Assays, Antitumor, 0210 nano-technology, Hydrophobic and Hydrophilic Interactions, Biotechnology, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0602f8eb7930bf89851877fd26e6ed9
https://pubmed.ncbi.nlm.nih.gov/33691403

المؤلفون: Natalia L. Klyachko, Elena V. Batrakova, Zigang Yang, Anton V Lopukhov, Marina Sokolsky-Papkov, Matthew J. Haney, Alexander V. Kabanov, Tatiana K. Bronich

المصدر: Macromol Biosci

مصطلحات موضوعية: Male, Magnetic Resonance Spectroscopy, Polymers and Plastics, Light, Polymers, Genetic enhancement, Mannose, Succinimides, Bioengineering, 02 engineering and technology, Gene delivery, 010402 general chemistry, Ligands, Microscopy, Atomic Force, 01 natural sciences, Article, Polyethylene Glycols, Biomaterials, chemistry.chemical_compound, Mice, C-type lectin, Cations, Materials Chemistry, Animals, Humans, Scattering, Radiation, Polylysine, Cytotoxicity, Aspartame, Macrophages, Gene Transfer Techniques, Transfection, DNA, Fibroblasts, 021001 nanoscience & nanotechnology, Molecular biology, Polyelectrolytes, 0104 chemical sciences, Cross-Linking Reagents, chemistry, Cell culture, Chromatography, Gel, NIH 3T3 Cells, 0210 nano-technology, Mannose receptor, Mannose Receptor, Biotechnology, Plasmids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aeca509775400f7d8f2898e5559c862
https://europepmc.org/articles/PMC8126558/

المؤلفون: Olga Y. Burenina, Dmitrii A Grishin, Yan A. Ivanenkov, Sergey V. Kovalev, Yury V. Timchenko, Alexander Vaneev, Svetlana Yu. Maklakova, Alexander G. Majouga, Natalia L. Klyachko, Rostislav A Petrov, Alexander Erofeev, Elena K. Beloglazkina, Emil Yu. Yamansarov, Roman Timoshenko, Petr V. Gorelkin, Elena V Lopatukhina, Evgenia E Ondar, Sergei A Evteev, Anton V Lopukhov, Sofiia R Mefedova

المصدر: Molecular pharmaceutics. 18(1)

مصطلحات موضوعية: Carcinoma, Hepatocellular, Glycoconjugate, Pharmaceutical Science, Asialoglycoprotein Receptor, Docetaxel, Small Molecule Libraries, Cell Line, Tumor, Drug Discovery, medicine, Humans, Cytotoxicity, chemistry.chemical_classification, Drug Carriers, Taxane, Chemistry, Liver Neoplasms, Hep G2 Cells, Prodrug, Ligand (biochemistry), Small molecule, HEK293 Cells, Biochemistry, Liver, A549 Cells, PC-3 Cells, Hepatocytes, Molecular Medicine, Asialoglycoprotein receptor, Glycoconjugates, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e137e7aecf403164e00f990463563d82
https://pubmed.ncbi.nlm.nih.gov/33264010

المؤلفون: Alexander N. Lobov, Natalia L. Klyachko, Olga Y. Burenina, Ivan V Kislyakov, Yan A. Ivanenkov, Galina S Reshitko, Sergey V. Kovalev, Elena K. Beloglazkina, Irina V. Saltykova, Alexander Erofeev, Dmitry O Shkil, Emil Yu. Yamansarov, Elena V Lopatukhina, Peter Gorelkin, Anastasiia S Garanina, Olga A. Dontsova, Alexander G. Majouga, Sergei A Evteev, Anton V Lopukhov

المصدر: Bioconjugate chemistry. 31(5)

مصطلحات موضوعية: Tris, Azides, Protein Conformation, In silico, Biomedical Engineering, Pharmaceutical Science, Bioengineering, Galactosamine, 02 engineering and technology, Asialoglycoprotein Receptor, Chemistry Techniques, Synthetic, Gene delivery, Ligands, 01 natural sciences, chemistry.chemical_compound, Humans, Surface plasmon resonance, Pharmacology, Esterification, 010405 organic chemistry, Chemistry, Ligand, Organic Chemistry, Hep G2 Cells, 021001 nanoscience & nanotechnology, Combinatorial chemistry, 0104 chemical sciences, Molecular Docking Simulation, Alkynes, Drug Design, Drug delivery, PC-3 Cells, Hepatocytes, Asialoglycoprotein receptor, 0210 nano-technology, Methane, Biotechnology, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a0036c9314579988adf7544e1bf3c5
https://pubmed.ncbi.nlm.nih.gov/32379426

المؤلفون: Emil Yu. Yamansarov (7355015), Elena V. Lopatukhina (8819903), Sergei A. Evteev (8819900), Dmitry A. Skvortsov (1773577), Anton V. Lopukhov (8819909), Sergey V. Kovalev (8819912), Alexander N. Vaneev (8904125), Dmitry O. Shkil’ (8819906), Roman A. Akasov (8814482), Alexander N. Lobov (7284218), Victor A. Naumenko (7516724), Ekaterina N. Pavlova (10288638), Oxana O. Ryabaya (8904134), Olga Yu. Burenina (8819918), Yan A. Ivanenkov (1745152), Natalia L. Klyachko (8819921), Alexander S. Erofeev (1853785), Petr V. Gorelkin (1853770), Elena K. Beloglazkina (1773589), Alexander G. Majouga (1773604)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Pharmacology, Biotechnology, Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, ligand, glycoconjugate, surface plasmon resonance tests, Hepatocellular Carcinoma Herein, reactive oxygen species, C -28 positions, hepatocyte, hepatocellular carcinoma, HepG 2 cells, bivalent conjugate, betulin, hepatocellular carcinoma cells HepG 2, agent, Bivalent GalNAc-Conjugated Betulin, Potent ASGPR-Directed Agent

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_Bivalent_GalNAc-Conjugated_Betulin_as_a_Potent_ASGPR-Directed_Agent_against_Hepatocellular_Carcinoma/14198241

الاتاحة: https://doi.org/10.1021/acs.bioconjchem.1c00042.s001