المؤلفون: Ahmed H. E. Hassan, Waleed A. Bayoumi, Selwan M. El-Sayed, Trong-Nhat Phan, Yeon Ju Kim, Chae Hyeon Lee, Soo Bin Cho, Taegeun Oh, Gyeongpyo Ham, Kazem Mahmoud, Joo Hwan No, Yong Sup Lee

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)

مصطلحات موضوعية: Antileishmanial agents, Visceral Leishmaniasis, Leishmania donovani, Promastigotes, Chromone, Repurposing, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

URL الوصول: https://doaj.org/article/75c3167bf0e4457789ff5626339f4bac

المؤلفون: Jila Sherafati, Mohammad Saaid Dayer, Fatemeh Ghaffarifar

المصدر: Parasites & Vectors, Vol 15, Iss 1, Pp 1-12 (2022)

مصطلحات موضوعية: Leishmania major, Antileishmanial agents, Larval excretion, Larval secretion, Lucilia sericata, Maggot therapy, Infectious and parasitic diseases, RC109-216

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1756-3305

URL الوصول: https://doaj.org/article/be39edc6f05a4dcf940a05efaa024631

المؤلفون: Shahla Amani, Shahram Khademvatan, Mehdi Mohebodini, Morad Jafari, Vinod Kumar

المصدر: Asian Pacific Journal of Tropical Medicine, Vol 15, Iss 5, Pp 220-229 (2022)

مصطلحات موضوعية: antileishmanial agents, hairy roots, ifn-γ, induc- ible nitric oxide synthase, parasite, reactive oxygen species, Arctic medicine. Tropical medicine, RC955-962

وصف الملف: electronic resource

Relation: http://www.apjtm.org/article.asp?issn=1995-7645;year=2022;volume=15;issue=5;spage=220;epage=229;aulast=Amani; https://doaj.org/toc/2352-4146

URL الوصول: https://doaj.org/article/5d01c74860b04734b75591351f3cf4bb

المؤلفون: Nawal Kishore Sahu, Ritu Sharma, Kshirsagar Prasad Suhas, Jyoti Joshi, Kunal Prakash, Richa Sharma, Ramendra Pratap, Xiwen Hu, Sukhbir Kaur, Mukesh Jain, Carmine Coluccini, Paolo Coghi, Sandeep Chaudhary

المصدر: Molecules; Volume 28; Issue 12; Pages: 4817

مصطلحات موضوعية: microwave-assisted synthesis, spirooxindole, antileishmanial agents, molecular docking studies, structure–activity relationship

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/molecules28124817

الاتاحة: https://doi.org/10.3390/molecules28124817

المؤلفون: Ahmed H.E. Hassan, Waleed A. Bayoumi, Selwan M. El-Sayed, Trong-Nhat Phan, Taegeun Oh, Gyeongpyo Ham, Kazem Mahmoud, Joo Hwan No, Yong Sup Lee

المصدر: Pharmaceuticals, Vol 16, Iss 11, p 1594 (2023)

مصطلحات موضوعية: antileishmanial agents, visceral leishmaniasis, Leishmania donovani, promastigotes, cinnamoyl-β-amino-α-ketoamides, drug repurposing, Medicine, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1424-8247/16/11/1594; https://doaj.org/toc/1424-8247

URL الوصول: https://doaj.org/article/b0f7750f5dbe410483d611246996ae7e

المؤلفون: Ahmed H. E. Hassan, Trong-Nhat Phan, Seolmin Yoon, Cheol Jung Lee, Hye Rim Jeon, Seung-Hwan Kim, Joo Hwan No, Yong Sup Lee

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1922-1930 (2021)

مصطلحات موضوعية: antileishmanial agents, promastigotes, amastigotes, repurposing, molecular docking, inositol phosphoceramide synthase, ipcs, sphingomyelin, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

URL الوصول: https://doaj.org/article/33781956a9284f9394ef0a3eb388e31d

المؤلفون: Philippe M. Loiseau, Kaluvu Balaraman, Gillian Barratt, Sébastien Pomel, Rémy Durand, Frédéric Frézard, Bruno Figadère

المصدر: Molecules ; Volume 27 ; Issue 7 ; Pages: 2313

مصطلحات موضوعية: antiparasitic drugs, 2-substituted quinolines, leishmaniasis, antileishmanial agents, mechanism of action, drug targeting

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules27072313

الاتاحة: https://doi.org/10.3390/molecules27072313

المؤلفون: Ahmed H.E. Hassan, Trong-Nhat Phan, Yeonwoo Choi, Suyeon Moon, Joo Hwan No, Yong Sup Lee

المصدر: Pharmaceuticals; Volume 15; Issue 9; Pages: 1058

مصطلحات موضوعية: antileishmanial agents, repurposing, Leishmania donovani, promastigotes, fumarate reductase

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/ph15091058

الاتاحة: https://doi.org/10.3390/ph15091058

المؤلفون: Jakob Bouton (9661745), Ludmila Ferreira de Almeida Fiuza (10500197), Camila Cardoso Santos (10500200), Maria Angela Mazzarella (10500203), Maria de Nazaré Correia Soeiro (10500206), Louis Maes (191127), Izet Karalic (1372623), Guy Caljon (119879), Serge Van Calenbergh (7411508)

مصطلحات موضوعية: Biochemistry, Medicine, Neuroscience, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, optimization efforts, Trypanosoma brucei, process purines, anti-Trypanosoma cruzi, vivo evaluation, nucleobase 7- position, pyrimidine Nucleosides, drug discovery, 7- modifications, antiparasitic agents, antileishmanial agents, Purine nucleoside analogues, anti-Trypanosoma cruzi activities, Chagas disease mouse model, purine synthesis, kinetoplastid parasites, Antileishmanial Agents Chagas disease

Relation: https://figshare.com/articles/journal_contribution/Revisiting_Pyrazolo_3_4_i_d_i_pyrimidine_Nucleosides_as_Anti-Trypanosoma_cruzi_and_Antileishmanial_Agents/14343053

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00135.s001

المؤلفون: Bazin, Marc-Antoine, Cojean, Sandrine, Pagniez, Fabrice, Bernadat, Guillaume, Cavé, Christian, Ourliac-Garnier, Isabelle, Nourrisson, Marie-Renée, Morgado, Cathy, Picot, Carine, Leclercq, Olivier, Baratte, Blandine, Robert, Thomas, Späth, Gerald F, Rachidi, Najma, Bach, Stéphane, Loiseau, Philippe, Le Pape, Patrice, Marchand, Pascal

المساهمون: Cibles et Médicaments des Infections et de l'Immunité - EA 1155 (IICiMed), Université de Nantes - UFR des Sciences Pharmaceutiques et Biologiques, Université de Nantes (UN)-Université de Nantes (UN), Biomolécules : Conception, Isolement, Synthèse (BioCIS), Institut de Chimie - CNRS Chimie (INC-CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-CY Cergy Paris Université (CY), Parasitologie moléculaire et Signalisation / Molecular Parasitology and Signaling, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire de Biologie Intégrative des Modèles Marins (LBI2M), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Station biologique de Roscoff = Roscoff Marine Station (SBR), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Station biologique de Roscoff = Roscoff Marine Station (SBR), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Fédération de recherche de Roscoff (FR2424), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), The authors gratefully acknowledge the Consortium against Parasites and Fungi (CaPF) for the scientific exchanges. Authors acknowledge the Corsaire-ThalassOMICS Metabolomics Facility (Biogenouest, University of Nantes, France) and UMR 6230 CEISAM Laboratory for HRMS analyses. The authors also thank GIS IBiSA (Infrastructures en Biologie Santé et Agronomie, France) and Biogenouest (Western France life science and environment core facility network) for supporting kinase screening facility (KISSf, Roscoff, France).

المصدر: ISSN: 0223-5234.

مصطلحات موضوعية: Antileishmanial agents, Casein kinase 1, Homology model, L-CK1.2 inhibitors, Imidazo[1, 2-a]pyrazines, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/33148491; PUBMED: 33148491

الاتاحة: https://pasteur.hal.science/pasteur-03108849
https://pasteur.hal.science/pasteur-03108849v1/document
https://pasteur.hal.science/pasteur-03108849v1/file/Manuscript_EJMECH-D-20-02458_revised_version%5B1%5D.pdf
https://doi.org/10.1016/j.ejmech.2020.112956

المؤلفون: Jared T. Hammill (246488), Vitaliy M. Sviripa (6470507), Liliia M. Kril (1967950), Diana Ortiz (727331), Corinne M. Fargo (11242073), Ho Shin Kim (2035261), Yizhe Chen (1416877), Jonah Rector (7382417), Amy L. Rice (9451406), Malgorzata A. Domagalska (8120537), Kristin L. Begley (11242076), Chunming Liu (72065), Vivek M. Rangnekar (3636745), Jean-Claude Dujardin (56958), David S. Watt (1316937), Scott M. Landfear (11242079), R. Kiplin Guy (160393)

مصطلحات موضوعية: Medicine, Pharmacology, Immunology, Physical Sciences not elsewhere classified, Potential Antileishmanial Agents Le., selectivity, EC 50, leishmaniasi, potently block proliferation, arylquinoline, Leishmania donovani parasites, intramacrophage amastigote form, antileishmanial

Relation: https://figshare.com/articles/journal_contribution/Amino-Substituted_3_Aryl-_and_3_Heteroarylquinolines_as_Potential_Antileishmanial_Agents/15124712

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00813.s002

المؤلفون: Ahmed H. E. Hassan (4806837), Trong-Nhat Phan (11324000), Seolmin Yoon (11324003), Cheol Jung Lee (11324006), Hye Rim Jeon (11324009), Seung-Hwan Kim (432137), Joo Hwan No (380434), Yong Sup Lee (2059930)

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Immunology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, Antileishmanial agents, promastigotes, amastigotes, repurposing, molecular docking, inositol phosphoceramide synthase, IPCS, sphingomyelin

Relation: https://figshare.com/articles/journal_contribution/Pyrrolidine-based_3-deoxysphingosylphosphorylcholine_analogs_as_possible_candidates_against_neglected_tropical_diseases_NTDs_identification_of_hit_compounds_towards_development_of_potential_treatment_of_i_Leishmania_donovani_i_/16418723

الاتاحة: https://doi.org/10.6084/m9.figshare.16418723.v1

المؤلفون: Alejandro Revuelto (6623636), Héctor de Lucio (6623642), Juan Carlos García-Soriano (10746239), Pedro A. Sánchez-Murcia (3205626), Federico Gago (60533), Antonio Jiménez-Ruiz (6623654), María-José Camarasa (1801147), Sonsoles Velázquez (2219341)

مصطلحات موضوعية: Biochemistry, Microbiology, Pharmacology, Biotechnology, Immunology, Infectious Diseases, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, novel antileishmanial agents, Leishmania infantum Trypanothione R., Li TryR, Leishmania infantum trypanothione d., Efficient Dimerization Disruption, Li TryR dimerization, novel triazole-bearing compounds, Molecular modeling studies

Relation: https://figshare.com/articles/journal_contribution/Efficient_Dimerization_Disruption_of_Leishmania_infantum_Trypanothione_Reductase_by_Triazole-phenyl-thiazoles/14537786

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00206.s001

المؤلفون: Masoud Keighobadi, Hassan Mirzaei, Mahdi Fakhar, Saeed Emami

المصدر: Journal of Mazandaran University of Medical Sciences, Vol 27, Iss 153, Pp 175-190 (2017)

مصطلحات موضوعية: azoles, antileishmanial agents, drug design, leishmaniasis, structure-activity relationship, Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://jmums.mazums.ac.ir/article-1-10219-en.html; https://doaj.org/toc/1735-9260; https://doaj.org/toc/1735-9279

URL الوصول: https://doaj.org/article/b71784f964764d42a59fe76dbba2f05f

المؤلفون: Michele Tonelli, Anna Sparatore, Nicoletta Basilico, Loredana Cavicchini, Silvia Parapini, Bruno Tasso, Erik Laurini, Sabrina Pricl, Vito Boido, Fabio Sparatore

المصدر: Pharmaceuticals; Volume 13; Issue 11; Pages: 339

مصطلحات موضوعية: Leishmania tropica and infantum, antileishmanial agents, lucanthone analogues, amitriptyline analogues, quinolizidine-derived compounds, molecular modelling studies

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/ph13110339

الاتاحة: https://doi.org/10.3390/ph13110339

المؤلفون: André Lopes, Nuno Santarém, Anabela Cordeiro-da-Silva, M. Alice Carvalho

المساهمون: Universidade do Minho

المصدر: ACS Medicinal Chemistry Letters. 13:1427-1433

مصطلحات موضوعية: pyrimido[5,4-d]pyrimidine derivatives, Science & Technology, novel class of antitrypanosomal agents, Organic Chemistry, Drug Discovery, novel class of antileishmanial agents, fused pyrimidine derivatives, Ciências Naturais::Ciências Químicas, Biochemistry

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f3277b2dd87ea2493cd73e48313a91
https://doi.org/10.1021/acsmedchemlett.2c00170

المؤلفون: Rando, Daniela Gonçalves, Giarolla, Jeanine, Pasqualoto, Kerly Fernanda Mesquita, Ferreira, Elizabeth Igne

المصدر: Brazilian Journal of Pharmaceutical Sciences. June 2010 46(2)

مصطلحات موضوعية: Chalcones, N-acylhydrazones, Antileishmanial agents, Leishmaniasis, Chemometrics

وصف الملف: text/html

URL الوصول: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000200019

المؤلفون: Martin-Montes, Alvaro, Plano, Daniel, Martin-Escolano, Ruben, Alcolea, Veronica, Diaz, Marta, Perez-Silanes, Silvia, Espuelas, Socorro, Moreno, Esther, Marin, Clotilde, Gutierrez-Sanchez, Ramon, Sanmartin, Carmen, Sanchez-Moreno, Manuel

المساهمون: Martin-Montes, Alvaro Univ Granada, Fac Ciencias, Dept Parasitol, Severo Ochoa S-N, Granada, Spain, Martin-Escolano, Ruben Univ Granada, Fac Ciencias, Dept Parasitol, Severo Ochoa S-N, Granada, Spain, Marin, Clotilde Univ Granada, Fac Ciencias, Dept Parasitol, Severo Ochoa S-N, Granada, Spain, Sanchez-Moreno, Manuel Univ Granada, Fac Ciencias, Dept Parasitol, Severo Ochoa S-N, Granada, Spain, Martin-Montes, Alvaro Hosp Univ Granada, Inst Invest Biosanitaria Ibs Granada, Granada, Spain, Martin-Escolano, Ruben Hosp Univ Granada, Inst Invest Biosanitaria Ibs Granada, Granada, Spain, Marin, Clotilde Hosp Univ Granada, Inst Invest Biosanitaria Ibs Granada, Granada, Spain, Sanchez-Moreno, Manuel Hosp Univ Granada, Inst Invest Biosanitaria Ibs Granada, Granada, Spain, Plano, Daniel Univ Navarra, Fac Pharm & Nutr, Dept Organ & Pharmaceut Chem, Campus Univ, Pamplona, Spain, Alcolea, Veronica Univ Navarra, Fac Pharm & Nutr, Dept Organ & Pharmaceut Chem, Campus Univ, Pamplona, Spain, Diaz, Marta Univ Navarra, Fac Pharm & Nutr, Dept Organ & Pharmaceut Chem, Campus Univ, Pamplona, Spain, Perez-Silanes, Silvia Univ Navarra, Fac Pharm & Nutr, Dept Organ & Pharmaceut Chem, Campus Univ, Pamplona, Spain, Sanmartin, Carmen Univ Navarra, Fac Pharm & Nutr, Dept Organ & Pharmaceut Chem, Campus Univ, Pamplona, Spain, Plano, Daniel Inst Invest Sanitaria Navarra, IdiSNA, Pamplona, Spain, Alcolea, Veronica Inst Invest Sanitaria Navarra, IdiSNA, Pamplona, Spain, Diaz, Marta Inst Invest Sanitaria Navarra, IdiSNA, Pamplona, Spain, Sanmartin, Carmen Inst Invest Sanitaria Navarra, IdiSNA, Pamplona, Spain, Perez-Silanes, Silvia Univ Navarra, Inst Trop Hlth, Pamplona, Spain, Espuelas, Socorro Univ Navarra, Inst Trop Hlth, Pamplona, Spain, Moreno, Esther Univ Navarra, Inst Trop Hlth, Pamplona, Spain, Gutierrez-Sanchez, Ramon Univ Granada, Dept Stat, Severo Ochoa S-N, Granada, Spain, Spanish MINECO, FEDER, FIMA (Fundacion para la Investigacion Medica Aplicada) project, FPU grant from Ministry of Education of Spain

مصطلحات موضوعية: Leishmania, selenium, superoxide dismutase, glucose metabolism, Potent antileishmanial agents, Visceral leishmaniasis, In-vitro, Redox modulators, Drug-resistance, Trypanosomatids, Promastigotes, Diselenides, Metabolism, Organoselenocyanates

Relation: http://hdl.handle.net/10668/19014; https://europepmc.org/articles/pmc5444169?pdf=render; 403783400040

الاتاحة: http://hdl.handle.net/10668/19014
https://doi.org/10.1128/AAC.02546-16
https://europepmc.org/articles/pmc5444169?pdf=render

المؤلفون: Daniela Gonçalves Rando, Jeanine Giarolla, Kerly Fernanda Mesquita Pasqualoto, Elizabeth Igne Ferreira

المصدر: Brazilian Journal of Pharmaceutical Sciences, Vol 46, Iss 2, Pp 311-321 (2010)

مصطلحات موضوعية: Chalconas, N-acilidrazonas, Agentes leishmanicidas, Leishmaniose, Quimiometria, Chalcones, N-acylhydrazones, Antileishmanial agents, Leishmaniasis, Chemometrics, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000200019; https://doaj.org/toc/1984-8250; https://doaj.org/toc/2175-9790

URL الوصول: https://doaj.org/article/3fb8253431b74cf2a11677751e39f4cb

المؤلفون: Tonelli, Michele, Sparatore, Anna, Basilico, Nicoletta, Cavicchini, Loredana, Parapini, Silvia, Tasso, Bruno, Laurini, Erik, Pricl, Sabrina, Boido, Vito, Sparatore, Fabio

المساهمون: Tonelli, Michele, Sparatore, Anna, Basilico, Nicoletta, Cavicchini, Loredana, Parapini, Silvia, Tasso, Bruno, Laurini, Erik, Pricl, Sabrina, Boido, Vito, Sparatore, Fabio

المصدر: Pharmaceuticals
Volume 13
Issue 11

مصطلحات موضوعية: Leishmania tropica and infantum, antileishmanial agents, lucanthone analogues, amitriptyline analogues, quinolizidine-derived compounds, molecular modelling studies, Amitriptyline analogues, Antileishmanial agents, Quinolizidine-derived compounds, amitriptyline analogue, Molecular modelling studies, quinolizidine-derived compound, Article, lucanthone analogue, Lucanthone analogues, parasitic diseases, antileishmanial agent

وصف الملف: ELETTRONICO; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::59ec8fee2a9167e7dea6c326f01b6f89
http://hdl.handle.net/11567/1029677