المؤلفون: Matthew D. Silva, Jason Ruan, Elizabeth Siebert, Anneli Savinainen, Bruce Jaffee, Lisa Schopf, Sudeep Chandra

المصدر: Molecular Imaging, Vol 5 (2006)

مصطلحات موضوعية: Biology (General), QH301-705.5, Medical technology, R855-855.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1536-0121

URL الوصول: https://doaj.org/article/72df5b31a33b4e2797a8f6fdb1c9d585

المؤلفون: Matthew D. Silva, Anneli Savinainen, Rasesh Kapadia, Jason Ruan, Elizabeth Siebert, Nicole Avitahl, Rebecca Mosher, Karen Anderson, Bruce Jaffee, Lisa Schopf, Sudeep Chandra

المصدر: Molecular Imaging, Vol 3 (2004)

مصطلحات موضوعية: Biology (General), QH301-705.5, Medical technology, R855-855.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1536-0121

URL الوصول: https://doaj.org/article/e74852415f1541ed9754ffd3ac44b8c3

المؤلفون: Jason J. Marineau (1355130), Kristin B. Hamman (11636925), Shanhu Hu (10909227), Sydney Alnemy (11636928), Janessa Mihalich (11636931), Anzhelika Kabro (2058655), Kenneth Matthew Whitmore (11636934), Dana K. Winter (1867471), Stephanie Roy (11636937), Stephane Ciblat (2506036), Nan Ke (11636940), Anneli Savinainen (11636943), Ashraf Wilsily (2097343), Goran Malojcic (7571429), Robert Zahler (2276440), Darby Schmidt (11636946), Michael J. Bradley (2495107), Nigel J. Waters (1370373), Claudio Chuaqui (1427743)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Hematology, Infectious Diseases, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, two important processes, mouse xenograft models, demonstrates strong efficacy, potent cellular activity, displays potent inhibition, orally available inhibitor, nm cdk7 k, ), 5609 , highly potent, noncovalent inhibitor, required potency, report describes, phosphine oxide, oncology due, nct04247126 ), metabolic stability

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_SY-5609_A_Selective_Noncovalent_Inhibitor_of_CDK7/16920012

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01171.s001

المؤلفون: Ruben V. Huis in ‘t Veld, Sen Ma, Rhonda C. Kines, Anneli Savinainen, Cadmus Rich, Ferry Ossendorp, Martine J. Jager

المصدر: Cancer Immunology, Immunotherapy.

مصطلحات موضوعية: Cancer Research, Oncology, Immunology, Immunology and Allergy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::866a2c21cb3f506bbd3a795085acea9a
https://doi.org/10.1007/s00262-023-03425-3

المؤلفون: Rhonda C. Kines, Anneli Savinainen, Elisabet de los Pinos, John T. Schiller

المصدر: Cancer Research. 83:1730-1730

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a80ea28473111449344e572c94b84412
https://doi.org/10.1158/1538-7445.am2023-1730

المؤلفون: Ashraf Wilsily, Robert Zahler, Nan Ke, Claudio Chuaqui, Michael J. Bradley, Jason J. Marineau, Goran Malojčić, Stephane Ciblat, Anneli Savinainen, Darby Schmidt, Nigel J. Waters, Kristin B. Hamman, Sydney Alnemy, Stephanie Roy, Dana K. Winter, Anzhelika Kabro, Kenneth Matthew Whitmore, Shanhu Hu, Janessa Mihalich

المصدر: Journal of medicinal chemistry. 65(2)

مصطلحات موضوعية: Mice, Nude, Apoptosis, Breast Neoplasms, chemistry.chemical_compound, Mice, Transcription (biology), Drug Discovery, Tumor Cells, Cultured, Potency, Animals, Humans, Protein Kinase Inhibitors, Cell Proliferation, Phosphine oxide, Mice, Inbred BALB C, Chemistry, Hydrogen bond, Cell Cycle, Cell cycle, Xenograft Model Antitumor Assays, Receptor–ligand kinetics, Cyclin-Dependent Kinases, Biochemistry, Cancer cell, Molecular Medicine, Female, Cyclin-dependent kinase 7, Cyclin-Dependent Kinase-Activating Kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a002487d311de55b839be03137541dfe
https://pubmed.ncbi.nlm.nih.gov/34726887

المؤلفون: Ruben Victor Huis in 't Veld, Sen Ma, Rhonda Kines, Anneli Savinainen, Cadmus Collins Rich, Ferry Ossendorp, Martine Jager

المصدر: Journal of Clinical Oncology. 40:e14544-e14544

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::42a64fccc00b67fd95bbb999ea761677
https://doi.org/10.1200/jco.2022.40.16_suppl.e14544

المؤلفون: Ivana K. Kim, Abhijit Narvekar, Cadmus C Rich, Anneli Savinainen

المصدر: Uveal Melanoma ISBN: 9783030781163

مصطلحات موضوعية: Bioconjugation, Chemistry, viruses, Melanoma, medicine.medical_treatment, Ocular Melanoma, Nanoparticle, Photodynamic therapy, medicine.disease, Capsid, medicine, Cancer research, Tumor necrosis factor alpha, Photosensitizer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d1f3f5b9cfaca37abd40bf1f54e5c0e5
https://doi.org/10.1007/978-3-030-78117-0_11

المؤلفون: Devin Welty, Alla Romashko, Serene Josiah, Steve Van Adestine, Chulbul M. Ahmed, Anneli Savinainen, Alfred S. Lewin, Brian Dwyer, Zhen Lou, Bohong Zhang, Eun-Hee Park

المصدر: Translational Vision Science & Technology

مصطلحات موضوعية: 0301 basic medicine, Retinal degeneration, Opsin, genetic structures, mouse model, Biomedical Engineering, Photoreceptor cell, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, retinitis pigmentosa, Retinitis pigmentosa, medicine, Outer nuclear layer, medicine.diagnostic_test, biology, Chemistry, pharmacologic chaperone, Retinal, Articles, medicine.disease, Cell biology, drug therapy, Ophthalmology, 030104 developmental biology, medicine.anatomical_structure, rhodopsin, Rhodopsin, 030221 ophthalmology & optometry, biology.protein, sense organs, Electroretinography

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d2777ba016a5ea108e126b32d2d219f
http://europepmc.org/articles/PMC6910612

المؤلفون: Anneli Savinainen, J. Cameron Millar, Iok-Hou Pang, Serene Josiah

المصدر: Experimental eye research. 188

مصطلحات موضوعية: 0301 basic medicine, Agonist, Intraocular pressure, Angiotensin receptor, genetic structures, medicine.drug_class, Ocular hypertension, Glaucoma, Administration, Ophthalmic, Pharmacology, Receptor, Angiotensin, Type 2, Aqueous Humor, 03 medical and health sciences, Cellular and Molecular Neuroscience, Mice, Tonometry, Ocular, 0302 clinical medicine, Trabecular Meshwork, medicine, Natriuretic peptide, Animals, Humans, Receptor, Cyclic GMP, Intraocular Pressure, Cell Line, Transformed, Chemistry, Natriuretic Peptide, C-Type, medicine.disease, eye diseases, Sensory Systems, Receptor, Cholecystokinin A, Mice, Inbred C57BL, Ophthalmology, 030104 developmental biology, medicine.anatomical_structure, 030221 ophthalmology & optometry, Female, sense organs, Trabecular meshwork, Ophthalmic Solutions, Receptors, Atrial Natriuretic Factor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dcb81d98d6db5fa3d5b29f25581558d
https://pubmed.ncbi.nlm.nih.gov/31421135

المؤلفون: Zita Kabok, Er Ibraghimov, Deirdre Torrey, Lillian Castriotta, Jacques Pappo, Anneli Savinainen, Alexander Ibraghimov

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://iai.asm.org/content/67/1/337.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.505.2185; http://iai.asm.org/content/67/1/337.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.505.2185
http://iai.asm.org/content/67/1/337.full.pdf

المؤلفون: Nan Ke, Anneli Savinainen, Liv Johannessen, Shanhu Hu, Anthony D'Ippolito, Jason J. Marineau, Graeme Hodgson, Nisha Rajagopal, William C. Zamboni

المصدر: Molecular Cancer Therapeutics. 18:C091-C091

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Fulvestrant, business.industry, Estrogen receptor, Palbociclib, Cell cycle, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, CDKN2A, 030220 oncology & carcinogenesis, Pharmacodynamics, Cancer research, Medicine, business, PK/PD models, Triple-negative breast cancer, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::79a28d1ec1fd4b80cd93b795ff3f8265
https://doi.org/10.1158/1535-7163.targ-19-c091

المؤلفون: Hassan Rashidzadeh, Anneli Savinainen, Justine Oswald, Elizabeth Spencer, Marita Larsson Cohen, Zhen Lou, Jeffery J Prusakiewicz, Serene Josiah

المصدر: Experimental Eye Research. 189:107836

مصطلحات موضوعية: 0301 basic medicine, Intraocular pressure, medicine.medical_specialty, genetic structures, Administration, Topical, Ocular hypertension, Glaucoma, Beagle, Aqueous Humor, 03 medical and health sciences, Cellular and Molecular Neuroscience, Dogs, 0302 clinical medicine, Pharmacokinetics, Ophthalmology, medicine, Animals, Antihypertensive Agents, Intraocular Pressure, EC50, Dose-Response Relationship, Drug, business.industry, Area under the curve, Natriuretic Peptide, C-Type, medicine.disease, eye diseases, Sensory Systems, Disease Models, Animal, Macaca fascicularis, 030104 developmental biology, Pharmacodynamics, 030221 ophthalmology & optometry, Female, Rabbits, sense organs, business, Glaucoma, Open-Angle, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff5b8e37f31eb2dfd600623e0ae3be5
https://doi.org/10.1016/j.exer.2019.107836

المؤلفون: Shanhu Hu, Jason Marineau, Kristin Hamman, Michael Bradley, Anneli Savinainen, Sydney Alnemy, Nisha Rajagopal, David Orlando, Claudio Chuaqui, Eric Olson

المصدر: Cancer Research. 79:4421-4421

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ee29d3815ed1cb58fb7a01014453bb43
https://doi.org/10.1158/1538-7445.am2019-4421

المؤلفون: Todd Schoen, Jacquelyn M. Guilford, Elizabeth R. B. Higdon, Ashley Brigham, Kyla Holmes, Nicole Giese, Dawn Costa, Tera Stock, Sara Jingst, Wendy Weissner, J. Katherine Bryan, Regina C. Windsor, Richard Isaac, Anneli Savinainen, Juila Kats, Erica Rusie, Julie Conquer, Laurie Peery, Catherine Ulbricht, Shaina Tanguay-Colucci

المصدر: Journal of Dietary Supplements. 9:57-77

مصطلحات موضوعية: Nutrition and Dietetics, Traditional medicine, biology, Plant Extracts, business.industry, Annatto Extract, Bixaceae, biology.organism_classification, Bixa, Humans, Medicine, Pharmacology (medical), Medicine, Traditional, business, Phytotherapy, Food Science

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa3866856580dff6d3eff17e9b3e851
https://doi.org/10.3109/19390211.2012.653530

المؤلفون: Serene Josiah, Galen Carey, Jennifer Newman, Kathy Derakhchan, Anneli Savinainen

المصدر: Journal of Pharmacological and Toxicological Methods. 93:149

مصطلحات موضوعية: Pharmacology, business.industry, Medicine, Hypothermia, medicine.symptom, Toxicology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5e2672cdd43b3d4f386c2cbe90c6a925
https://doi.org/10.1016/j.vascn.2018.01.492

المؤلفون: John Marshall, Donna S. Dorow, Elizabeth P. Garcia, Anneli Savinainen, Ya Fang Liu

المصدر: Journal of Biological Chemistry. 276:11382-11386

مصطلحات موضوعية: Receptor complex, Cell signaling, MAP Kinase Kinase 4, MAP Kinase Signaling System, Excitotoxicity, Nerve Tissue Proteins, Kainate receptor, Mitogen-activated protein kinase kinase, Biology, medicine.disease_cause, Biochemistry, SH3 domain, Receptors, Kainic Acid, medicine, Animals, Molecular Biology, Mitogen-Activated Protein Kinase Kinases, Neurons, Kinase, Intracellular Signaling Peptides and Proteins, JNK Mitogen-Activated Protein Kinases, Glutamate receptor, Membrane Proteins, Cell Biology, MAP Kinase Kinase Kinases, Molecular biology, Rats, Cell biology, nervous system, Disks Large Homolog 4 Protein, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc84cc2cf93359ea01467d1f3c52cc9
https://doi.org/10.1074/jbc.m100190200

المؤلفون: Julie Kujawa, Yajun Xu, Danyi Wen, Matthew D. Silva, Michelle Dupont, Jennifer G. Morgan, Lisa Schopf, Pranoti Gangurde, Bruce Jaffee, Anneli Savinainen, Karen Anderson, Joan H. Lane, Sudeep Chandra, Geraldine C Harriman, Elizabeth Siebert, Michael E. Hepperle, Timothy D. Ocain

المصدر: Arthritis and rheumatism. 54(10)

مصطلحات موضوعية: Niacinamide, Pathology, medicine.medical_specialty, Immunology, Freund's Adjuvant, Arthritis, Inflammation, Cartilage metabolism, Pharmacology, Bone and Bones, Arthritis, Rheumatoid, Rheumatology, medicine, Immunology and Allergy, Animals, Pharmacology (medical), Dose-Response Relationship, Drug, business.industry, Tumor Necrosis Factor-alpha, Cartilage, NF-kappa B, medicine.disease, Arthritis, Experimental, I-kappa B Kinase, Rats, Disease Models, Animal, medicine.anatomical_structure, Gene Expression Regulation, Freund's adjuvant, Rats, Inbred Lew, Rheumatoid arthritis, Polyarthritis, Female, medicine.symptom, business, Type I collagen, Carbolines

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8b48f8be9f8bbf4cc7bbfda7ae2438
https://pubmed.ncbi.nlm.nih.gov/17009244

المؤلفون: Alexander Ibraghimov, Castriotta Lillian Marie, Deirdre Torrey, Anneli Savinainen, Kabok Zita, Jacques Pappo

المصدر: Infection and immunity. 67(1)

مصطلحات موضوعية: Cellular immunity, Immunology, Administration, Oral, chemical and pharmacologic phenomena, Major histocompatibility complex, Microbiology, Helicobacter Infections, Immunophenotyping, Mice, Immune system, Antigen, Cell Movement, MHC class I, Animals, Mice, Knockout, MHC class II, Antigens, Bacterial, biology, Helicobacter pylori, Histocompatibility Antigens Class I, Histocompatibility Antigens Class II, Bacterial vaccine, Mice, Inbred C57BL, Infectious Diseases, Gastric Mucosa, Bacterial Vaccines, Microbial Immunity and Vaccines, biology.protein, Leukocytes, Mononuclear, Parasitology, CD8

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c90f22227c721796e46efe18dc2ead6
https://pubmed.ncbi.nlm.nih.gov/9864234

المؤلفون: Lisa Schopf¹, Anneli Savinainen¹, Karen Anderson¹, Julie Kujawa¹, Michelle DuPont¹, Matthew Silva¹, Elizabeth Siebert¹, Sudeep Chandra¹, Jennifer Morgan¹, Pranoti Gangurde¹, Danyi Wen¹, Joan Lane¹, Yajun Xu¹, Michael Hepperle¹, Geraldine Harriman¹, Timothy Ocain¹, Bruce Jaffee¹

المصدر: Arthritis & Rheumatism. Oct2006, Vol. 54 Issue 10, p3163-3173. 11p.

مصطلحات موضوعية: *RHEUMATOID arthritis, *IMMUNOLOGICAL adjuvants, *LABORATORY rats, *MESSENGER RNA, *BODY weight