المؤلفون: Gert de Wilde, Maarten Gees, Sara Musch, Katleen Verdonck, Mia Jans, Anne-Sophie Wesse, Ashvani K. Singh, Tzyh-Chang Hwang, Thierry Christophe, Mathieu Pizzonero, Steven Van der Plas, Nicolas Desroy, Marlon Cowart, Pieter Stouten, Luc Nelles, Katja Conrath

المصدر: Frontiers in Pharmacology, Vol 10 (2019)

مصطلحات موضوعية: cystic fibrosis transmembrane conductance regulator (CFTR), cystic fibrosis, chloride channel, electrophysiology, protein misfolding, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2019.00514/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/8d68380c55104f5f99c3962f9d0c136b

المؤلفون: Maarten Gees, Sara Musch, Steven Van der Plas, Anne-Sophie Wesse, Ann Vandevelde, Katleen Verdonck, Oscar Mammoliti, Tzyh-Chang Hwang, Kathleen Sonck, Pieter Stouten, Andrew M. Swensen, Mia Jans, Jan Van der Schueren, Luc Nelles, Martin Andrews, Katja Conrath

المصدر: Frontiers in Pharmacology, Vol 9 (2018)

مصطلحات موضوعية: CF, CFTR, potentiator, bronchial epithelial cells, electrophysiology, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2018.01221/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/99852fe337bc4182a943b73d103f71f5

المؤلفون: Dominique Lambin, Katja Conrath, Tom De Munck, Ann De Blieck, Hans Kelgtermans, Steven Emiel Van Der Plas, Marlon D. Cowart, Christel Jeanne Marie Menet, Sebastien Dropsit, Caroline Joannesse, Oscar Mammoliti, Sebastien Laurent Xavier Martina, Maarten Gees, Giovanni Tricarico, Martin James Inglis Andrews, Anne-Sophie Wesse

المصدر: Journal of Medicinal Chemistry. 64:343-353

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Cystic Fibrosis, Pyridines, Cystic Fibrosis Transmembrane Conductance Regulator, Gating, Computational biology, 01 natural sciences, Cystic fibrosis, Ivacaftor, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, medicine, Animals, Humans, 030304 developmental biology, 0303 health sciences, biology, Drug discovery, Lumacaftor, Potentiator, medicine.disease, Small molecule, Cystic fibrosis transmembrane conductance regulator, Rats, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry, biology.protein, Molecular Medicine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c3164798d3ba2edd8da65585ae94bc
https://doi.org/10.1021/acs.jmedchem.0c01796

المؤلفون: Steven Emiel Van Der Plas, Ann De Blieck, Dominique Lambin, Giovanni Tricarico, Martin James Inglis Andrews, Anne-Sophie Wesse, Marlon D. Cowart, Katja Conrath, Tom De Munck, Maarten Gees, Christel Jeanne Marie Menet, Hans Kelgtermans, Oscar Mammoliti, Caroline Joannesse, Sebastien Laurent Xavier Martina, Sebastien Dropsit

المصدر: Journal of Medicinal Chemistry. 64:13933-13933

مصطلحات موضوعية: Chemistry, Drug Discovery, MEDLINE, medicine, Molecular Medicine, Potentiator, Once daily, medicine.disease, Bioinformatics, Cystic fibrosis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ef530fe540a7f240ca9942862582716b
https://doi.org/10.1021/acs.jmedchem.1c01537

المؤلفون: Anne Sophie Wesse, Nicolas Desroy, Mathieu Rafaël Pizzonero, Mia Jans, Steven Emiel Van Der Plas, Katleen Verdonck, Katja Conrath, Tzyh Chang Hwang, Ashvani K. Singh, Gert Jules Hector De Wilde, Thierry Christophe, Pieter F. W. Stouten, Maarten Gees, Luc Nelles, Sara Musch, Marlon Cowart

المصدر: Frontiers in Pharmacology, Vol 10 (2019)
Frontiers in Pharmacology

مصطلحات موضوعية: 0301 basic medicine, chloride channel, Computational biology, medicine.disease_cause, Cystic fibrosis, Unmet needs, cystic fibrosis, 03 medical and health sciences, 0302 clinical medicine, medicine, Pharmacology (medical), protein misfolding, Original Research, Pharmacology, Mutation, biology, business.industry, lcsh:RM1-950, medicine.disease, electrophysiology, Cystic fibrosis transmembrane conductance regulator, 030104 developmental biology, lcsh:Therapeutics. Pharmacology, 030220 oncology & carcinogenesis, Chloride channel, biology.protein, cystic fibrosis transmembrane conductance regulator (CFTR), business, Cftr modulator

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d914b2d0b2021abba128959645f2bf
https://www.frontiersin.org/article/10.3389/fphar.2019.00514/full

المؤلفون: Kathleen Sonck, Mia Jans, Katja Conrath, Ann Vandevelde, Andrew M. Swensen, Pieter F. W. Stouten, Oscar Mammoliti, Maarten Gees, Katleen Verdonck, Steven Emiel Van Der Plas, Anne Sophie Wesse, Jan Van Der Schueren, Luc Nelles, Martin James Inglis Andrews, Sara Musch, Tzyh Chang Hwang

المصدر: Frontiers in Pharmacology, Vol 9 (2018)
Frontiers in Pharmacology

مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, Class iii, Pharmacology, Cystic fibrosis, Unmet needs, 03 medical and health sciences, medicine, F508del cftr, Pharmacology (medical), In patient, CFTR, bronchial epithelial cells, Original Research, biology, Chemistry, lcsh:RM1-950, CF, potentiator, Potentiator, respiratory system, medicine.disease, electrophysiology, Cystic fibrosis transmembrane conductance regulator, 030104 developmental biology, lcsh:Therapeutics. Pharmacology, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fee33c28983985798adc777f3acffec6
https://www.frontiersin.org/article/10.3389/fphar.2018.01221/full

المؤلفون: Gert de Wilde, Maarten Gees, Sara Musch, Katleen Verdonck, Mia Jans, Anne-Sophie Wesse, Ashvani K. Singh, Tzyh-Chang Hwang, Thierry Christophe, Mathieu Pizzonero, Steven Van der Plas, Nicolas Desroy, Marlon Cowart, Pieter Stouten, Luc Nelles, Katja Conrath

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, cystic fibrosis transmembrane conductance regulator (CFTR), cystic fibrosis, chloride channel, electrophysiology, protein misfolding

Relation: https://figshare.com/articles/dataset/Data_Sheet_1_Identification_of_GLPG_ABBV-2737_a_Novel_Class_of_Corrector_Which_Exerts_Functional_Synergy_With_Other_CFTR_Modulators_pdf/8100470

الاتاحة: https://doi.org/10.3389/fphar.2019.00514.s001
https://figshare.com/articles/dataset/Data_Sheet_1_Identification_of_GLPG_ABBV-2737_a_Novel_Class_of_Corrector_Which_Exerts_Functional_Synergy_With_Other_CFTR_Modulators_pdf/8100470

المؤلفون: Maarten Gees, Sara Musch, Steven Van der Plas, Anne-Sophie Wesse, Ann Vandevelde, Katleen Verdonck, Oscar Mammoliti, Tzyh-Chang Hwang, Kathleen Sonck, Pieter Stouten, Andrew M. Swensen, Mia Jans, Jan Van der Schueren, Luc Nelles, Martin Andrews, Katja Conrath

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, CF, CFTR, potentiator, bronchial epithelial cells, electrophysiology

Relation: https://figshare.com/articles/dataset/Data_Sheet_1_Identification_and_Characterization_of_Novel_CFTR_Potentiators_PDF/7256819

الاتاحة: https://doi.org/10.3389/fphar.2018.01221.s001
https://figshare.com/articles/dataset/Data_Sheet_1_Identification_and_Characterization_of_Novel_CFTR_Potentiators_PDF/7256819