المؤلفون: Mark P. Grillo (2413657), Svetlana Markova (3545603), Marc Evanchik (5806811), Marc Trellu (9650521), Patricia Moliner (9650524), Priscilla Brun (5806805), Anne Perreard-Dumaine (9650527), Pascale Vicat (8053706), Chun Yang (251691), James P. Driscoll (2159146), Tim J. Carlson (9650530)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, Cardiac myosin activator, danicamtiv, MYK-491, pharmacokinetics, allometric scaling, human prediction, metabolites

Relation: https://figshare.com/articles/journal_contribution/Preclinical_i_in_vitro_i_and_i_in_vivo_i_pharmacokinetic_properties_of_danicamtiv_a_new_targeted_myosin_activator_for_the_treatment_of_dilated_cardiomyopathy/13246147

الاتاحة: https://doi.org/10.6084/m9.figshare.13246147.v2

المؤلفون: Mark P. Grillo, Svetlana Markova, Marc Evanchik, Marc Trellu, Patricia Moliner, Priscilla Brun, Anne Perreard-Dumaine, Pascale Vicat, Chun Yang, James P. Driscoll, Tim J. Carlson

المصدر: Xenobiotica. 51:222-238

مصطلحات موضوعية: medicine.medical_specialty, Health, Toxicology and Mutagenesis, Toxicology, Left ventricular enlargement, 030226 pharmacology & pharmacy, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, In vivo, Internal medicine, Myosin, medicine, cardiovascular diseases, Pharmacology, business.industry, Activator (genetics), Dilated cardiomyopathy, General Medicine, medicine.disease, In vitro, 030220 oncology & carcinogenesis, Heart failure, cardiovascular system, Cardiology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6e1361f51b200ee3d2f156a0c2ce1187
https://doi.org/10.1080/00498254.2020.1839982

المؤلفون: Mark P, Grillo, Svetlana, Markova, Marc, Evanchik, Marc, Trellu, Patricia, Moliner, Priscilla, Brun, Anne, Perreard-Dumaine, Pascale, Vicat, James P, Driscoll, Tim J, Carlson

المصدر: Xenobiotica; the fate of foreign compounds in biological systems. 51(2)

مصطلحات موضوعية: Cardiomyopathy, Dilated, Male, Mice, Dogs, Hepatocytes, Microsomes, Liver, Animals, Biological Availability, Humans, Caco-2 Cells, Myosins, Protein Binding, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::63a8a54159ce8826d017fcbd171c2378
https://pubmed.ncbi.nlm.nih.gov/33078965