المؤلفون: Jonas Sundén-Cullberg, Puran Chen, Henrike Häbel, Paul Skorup, Helena Janols, Johan Rasmuson, Katarina Niward, Åse Östholm Balkhed, Katerina Chatzidionysiou, Hilmir Asgeirsson, Ola Blennow, Åsa Parke, Anna-Karin Svensson, Jagadeeswara Rao Muvva, Hans-Gustav Ljunggren, Anna-Carin Horne, Ulrika Ådén, Jan-Inge Henter, Anders Sönnerborg, Jan Vesterbacka, Piotr Nowak, Jon Lampa

المصدر: PLoS ONE, Vol 18, Iss 12 (2023)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10756513/?tool=EBI; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/e39fc73c24b240d8b53e00e77e5a9c10

المؤلفون: Karin Palmblad, Hanna Schierbeck, Erik Sundberg, Anna-Carin Horne, Helena Erlandsson Harris, Jan-Inge Henter, Ulf Andersson

المصدر: Molecular Medicine, Vol 27, Iss 1, Pp 1-13 (2021)

مصطلحات موضوعية: HMGB1, Macrophage activation syndrome, HLH, FHL, Inflammation, Pathogenesis, Therapeutics. Pharmacology, RM1-950, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1076-1551; https://doaj.org/toc/1528-3658

URL الوصول: https://doaj.org/article/a55408e06b2342e3acfc4027a7532cf9

المؤلفون: Karin Palmblad, Hanna Schierbeck, Erik Sundberg, Anna-Carin Horne, Helena Erlandsson Harris, Jan-Inge Henter, Daniel J. Antoine, Ulf Andersson

المصدر: Molecular Medicine, Vol 26, Iss 1, Pp 1-2 (2020)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1076-1551; https://doaj.org/toc/1528-3658

URL الوصول: https://doaj.org/article/faf37b5b47294b398ed794f08ce9ef7b

المؤلفون: Karin Palmblad, Hanna Schierbeck, Erik Sundberg, Anna-Carin Horne, Helena Erlandsson Harris, Jan-Inge Henter, Daniel J. Antoine, Ulf Andersson

المصدر: Molecular Medicine, Vol 26, Iss 1, Pp 1-1 (2020)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1076-1551; https://doaj.org/toc/1528-3658

URL الوصول: https://doaj.org/article/ec7b06ddb2584af5ab470b51b623fae6

المؤلفون: Jonas Sundén-Cullberg, Puran Chen, Henrike Häbel, Paul Skorup, Helena Janols, Johan Rasmuson, Katarina Niward, Åse Östholm Balkhed, Katerina Chatzidionysiou, Hilmir Asgeirsson, Ola Blennow, Åsa Parke, Anna-Karin Svensson, Jagadeeswara Rao Muvva, Hans-Gustav Ljunggren, Anna-Carin Horne, Ulrika Ådén, Jan-Inge Henter, Anders Sönnerborg, Jan Vesterbacka, Piotr Nowak, Jon Lampa

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Neuroscience, Physiology, Biotechnology, Immunology, Developmental Biology, Mental Health, Infectious Diseases, Virology, +recruitment%22">xlink "> recruitment, least two points, conducted june 2020, 2020 &# 8211, +anakinra%22">xlink "> anakinra, limited degree anakinra, tocilizumab became part, significantly shorten time, randomly assigned 1, planned 195 patients, dimer ≥ 0, clinical recovery compared, ci ], uc vs anakinra, vs uc, usual care, uc alone, single dose

Relation: https://figshare.com/articles/journal_contribution/Consort_checklist_/24919130

الاتاحة: https://doi.org/10.1371/journal.pone.0295838.s004
https://figshare.com/articles/journal_contribution/Consort_checklist_/24919130

المؤلفون: Jonas Sundén-Cullberg, Puran Chen, Henrike Häbel, Paul Skorup, Helena Janols, Johan Rasmuson, Katarina Niward, Åse Östholm Balkhed, Katerina Chatzidionysiou, Hilmir Asgeirsson, Ola Blennow, Åsa Parke, Anna-Karin Svensson, Jagadeeswara Rao Muvva, Hans-Gustav Ljunggren, Anna-Carin Horne, Ulrika Ådén, Jan-Inge Henter, Anders Sönnerborg, Jan Vesterbacka, Piotr Nowak, Jon Lampa

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Neuroscience, Physiology, Biotechnology, Immunology, Developmental Biology, Mental Health, Infectious Diseases, Virology, +recruitment%22">xlink "> recruitment, least two points, conducted june 2020, 2020 &# 8211, +anakinra%22">xlink "> anakinra, limited degree anakinra, tocilizumab became part, significantly shorten time, randomly assigned 1, planned 195 patients, dimer ≥ 0, clinical recovery compared, ci ], uc vs anakinra, vs uc, usual care, uc alone, single dose

Relation: https://figshare.com/articles/journal_contribution/Adverse_events_by_day_60_/24919127

الاتاحة: https://doi.org/10.1371/journal.pone.0295838.s003
https://figshare.com/articles/journal_contribution/Adverse_events_by_day_60_/24919127

المؤلفون: Jonas Sundén-Cullberg, Puran Chen, Henrike Häbel, Paul Skorup, Helena Janols, Johan Rasmuson, Katarina Niward, Åse Östholm Balkhed, Katerina Chatzidionysiou, Hilmir Asgeirsson, Ola Blennow, Åsa Parke, Anna-Karin Svensson, Jagadeeswara Rao Muvva, Hans-Gustav Ljunggren, Anna-Carin Horne, Ulrika Ådén, Jan-Inge Henter, Anders Sönnerborg, Jan Vesterbacka, Piotr Nowak, Jon Lampa

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Neuroscience, Physiology, Biotechnology, Immunology, Developmental Biology, Mental Health, Infectious Diseases, Virology, +recruitment%22">xlink "> recruitment, least two points, conducted june 2020, 2020 &# 8211, +anakinra%22">xlink "> anakinra, limited degree anakinra, tocilizumab became part, significantly shorten time, randomly assigned 1, planned 195 patients, dimer ≥ 0, clinical recovery compared, ci ], uc vs anakinra, vs uc, usual care, uc alone, single dose

Relation: https://figshare.com/articles/journal_contribution/Inclusion_and_exclusion_criteria_/24918527

الاتاحة: https://doi.org/10.1371/journal.pone.0295838.s001
https://figshare.com/articles/journal_contribution/Inclusion_and_exclusion_criteria_/24918527

المؤلفون: Jonas Sundén-Cullberg, Puran Chen, Henrike Häbel, Paul Skorup, Helena Janols, Johan Rasmuson, Katarina Niward, Åse Östholm Balkhed, Katerina Chatzidionysiou, Hilmir Asgeirsson, Ola Blennow, Åsa Parke, Anna-Karin Svensson, Jagadeeswara Rao Muvva, Hans-Gustav Ljunggren, Anna-Carin Horne, Ulrika Ådén, Jan-Inge Henter, Anders Sönnerborg, Jan Vesterbacka, Piotr Nowak, Jon Lampa

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Neuroscience, Physiology, Biotechnology, Immunology, Developmental Biology, Mental Health, Infectious Diseases, Virology, +recruitment%22">xlink "> recruitment, least two points, conducted june 2020, 2020 &# 8211, +anakinra%22">xlink "> anakinra, limited degree anakinra, tocilizumab became part, significantly shorten time, randomly assigned 1, planned 195 patients, dimer ≥ 0, clinical recovery compared, ci ], uc vs anakinra, vs uc, usual care, uc alone, single dose

Relation: https://figshare.com/articles/journal_contribution/Protocol_amendments_during_study_/24919136

الاتاحة: https://doi.org/10.1371/journal.pone.0295838.s006
https://figshare.com/articles/journal_contribution/Protocol_amendments_during_study_/24919136

المؤلفون: Jonas Sundén-Cullberg, Puran Chen, Henrike Häbel, Paul Skorup, Helena Janols, Johan Rasmuson, Katarina Niward, Åse Östholm Balkhed, Katerina Chatzidionysiou, Hilmir Asgeirsson, Ola Blennow, Åsa Parke, Anna-Karin Svensson, Jagadeeswara Rao Muvva, Hans-Gustav Ljunggren, Anna-Carin Horne, Ulrika Ådén, Jan-Inge Henter, Anders Sönnerborg, Jan Vesterbacka, Piotr Nowak, Jon Lampa

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Neuroscience, Physiology, Biotechnology, Immunology, Developmental Biology, Mental Health, Infectious Diseases, Virology, +recruitment%22">xlink "> recruitment, least two points, conducted june 2020, 2020 &# 8211, +anakinra%22">xlink "> anakinra, limited degree anakinra, tocilizumab became part, significantly shorten time, randomly assigned 1, planned 195 patients, dimer ≥ 0, clinical recovery compared, ci ], uc vs anakinra, vs uc, usual care, uc alone, single dose

Relation: https://figshare.com/articles/journal_contribution/Causes_of_death_/24919142

الاتاحة: https://doi.org/10.1371/journal.pone.0295838.s008
https://figshare.com/articles/journal_contribution/Causes_of_death_/24919142

المؤلفون: Jonas Sundén-Cullberg, Puran Chen, Henrike Häbel, Paul Skorup, Helena Janols, Johan Rasmuson, Katarina Niward, Åse Östholm Balkhed, Katerina Chatzidionysiou, Hilmir Asgeirsson, Ola Blennow, Åsa Parke, Anna-Karin Svensson, Jagadeeswara Rao Muvva, Hans-Gustav Ljunggren, Anna-Carin Horne, Ulrika Ådén, Jan-Inge Henter, Anders Sönnerborg, Jan Vesterbacka, Piotr Nowak, Jon Lampa

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Neuroscience, Physiology, Biotechnology, Immunology, Developmental Biology, Mental Health, Infectious Diseases, Virology, +recruitment%22">xlink "> recruitment, least two points, conducted june 2020, 2020 &# 8211, +anakinra%22">xlink "> anakinra, limited degree anakinra, tocilizumab became part, significantly shorten time, randomly assigned 1, planned 195 patients, dimer ≥ 0, clinical recovery compared, ci ], uc vs anakinra, vs uc, usual care, uc alone, single dose

Relation: https://figshare.com/articles/journal_contribution/Study_protocol_ImmCoVA_v_4_0_/24919133

الاتاحة: https://doi.org/10.1371/journal.pone.0295838.s005
https://figshare.com/articles/journal_contribution/Study_protocol_ImmCoVA_v_4_0_/24919133

المؤلفون: Jonas Sundén-Cullberg, Puran Chen, Henrike Häbel, Paul Skorup, Helena Janols, Johan Rasmuson, Katarina Niward, Åse Östholm Balkhed, Katerina Chatzidionysiou, Hilmir Asgeirsson, Ola Blennow, Åsa Parke, Anna-Karin Svensson, Jagadeeswara Rao Muvva, Hans-Gustav Ljunggren, Anna-Carin Horne, Ulrika Ådén, Jan-Inge Henter, Anders Sönnerborg, Jan Vesterbacka, Piotr Nowak, Jon Lampa

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Neuroscience, Physiology, Biotechnology, Immunology, Developmental Biology, Mental Health, Infectious Diseases, Virology, +recruitment%22">xlink "> recruitment, least two points, conducted june 2020, 2020 &# 8211, +anakinra%22">xlink "> anakinra, limited degree anakinra, tocilizumab became part, significantly shorten time, randomly assigned 1, planned 195 patients, dimer ≥ 0, clinical recovery compared, ci ], uc vs anakinra, vs uc, usual care, uc alone, single dose

Relation: https://figshare.com/articles/journal_contribution/Severe_adverse_events_by_day_60_/24919124

الاتاحة: https://doi.org/10.1371/journal.pone.0295838.s002
https://figshare.com/articles/journal_contribution/Severe_adverse_events_by_day_60_/24919124

المؤلفون: Jonas Sundén-Cullberg, Puran Chen, Henrike Häbel, Paul Skorup, Helena Janols, Johan Rasmuson, Katarina Niward, Åse Östholm Balkhed, Katerina Chatzidionysiou, Hilmir Asgeirsson, Ola Blennow, Åsa Parke, Anna-Karin Svensson, Jagadeeswara Rao Muvva, Hans-Gustav Ljunggren, Anna-Carin Horne, Ulrika Ådén, Jan-Inge Henter, Anders Sönnerborg, Jan Vesterbacka, Piotr Nowak, Jon Lampa

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Neuroscience, Physiology, Biotechnology, Immunology, Developmental Biology, Mental Health, Infectious Diseases, Virology, +recruitment%22">xlink "> recruitment, least two points, conducted june 2020, 2020 &# 8211, +anakinra%22">xlink "> anakinra, limited degree anakinra, tocilizumab became part, significantly shorten time, randomly assigned 1, planned 195 patients, dimer ≥ 0, clinical recovery compared, ci ], uc vs anakinra, vs uc, usual care, uc alone, single dose

Relation: https://figshare.com/articles/journal_contribution/Recruitment_interruption_and_adherence_to_protocol_/24919139

الاتاحة: https://doi.org/10.1371/journal.pone.0295838.s007
https://figshare.com/articles/journal_contribution/Recruitment_interruption_and_adherence_to_protocol_/24919139

المؤلفون: Heshuang Qu (11884661), Erik Sundberg (18849), Cecilia Aulin (5323142), Manoj Neog (9774308), Karin Palmblad (32044), Anna Carin Horne (11884664), Fredrik Granath (282503), Alexandra Ek (11884667), Erik Melén (276082), Mia Olsson (227252), Helena Erlandsson Harris (11884670)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Physiology, Ecology, Immunology, Developmental Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Systemic juvenile idiopathic arthritis, Cytokines and inflammatory mediators, Inflammation, Proteomics, Ingenuity pathway analysis, High mobility group Box 1

Relation: https://figshare.com/articles/journal_contribution/Additional_file_1_of_Immunoprofiling_of_active_and_inactive_systemic_juvenile_idiopathic_arthritis_reveals_distinct_biomarkers_a_single-center_study/17701610

الاتاحة: https://doi.org/10.6084/m9.figshare.17701610.v1

المؤلفون: Heshuang Qu, Erik Sundberg, Cecilia Aulin, Manoj Neog, Karin Palmblad, Anna Carin Horne, Fredrik Granath, Alexandra Ek, Erik Melén, Mia Olsson, Helena Erlandsson Harris

المصدر: Pediatric Rheumatology Online Journal, Vol 19, Iss 1, Pp 1-13 (2021)

مصطلحات موضوعية: Systemic juvenile idiopathic arthritis, Cytokines and inflammatory mediators, Inflammation, Proteomics, Ingenuity pathway analysis, High mobility group Box 1, Pediatrics, RJ1-570, Diseases of the musculoskeletal system, RC925-935

Relation: https://doi.org/10.1186/s12969-021-00660-9; https://doaj.org/toc/1546-0096; https://doaj.org/article/869822238e8b4c7da7c4103d2be7da08

الاتاحة: https://doi.org/10.1186/s12969-021-00660-9
https://doaj.org/article/869822238e8b4c7da7c4103d2be7da08

المؤلفون: Jonas Sundén-Cullberg, Puran Chen, Henrike Häbel, Paul Skorup, Helena Janols, Johan Rasmuson, Katarina Niward, Åse Östholm Balkhed, Katerina Chatzidionysiou, Hilmir Asgeirsson, Ola Blennow, Åsa Parke, Anna-Karin Svensson, Jagadeeswara Rao Muvva, Hans-Gustav Ljunggren, Anna-Carin Horne, Ulrika Ådén, Jan-Inge Henter, Anders Sönnerborg, Jan Vesterbacka, Piotr Nowak, Jon Lampa

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Neuroscience, Physiology, Biotechnology, Immunology, Developmental Biology, Mental Health, Infectious Diseases, Virology, +recruitment%22">xlink "> recruitment, least two points, conducted june 2020, 2020 &# 8211, +anakinra%22">xlink "> anakinra, limited degree anakinra, tocilizumab became part, significantly shorten time, randomly assigned 1, planned 195 patients, dimer ≥ 0, clinical recovery compared, ci ], uc vs anakinra, vs uc, usual care, uc alone, single dose

Relation: https://figshare.com/articles/dataset/Primary_and_secondary_outcomes_/24919160

الاتاحة: https://doi.org/10.1371/journal.pone.0295838.t002
https://figshare.com/articles/dataset/Primary_and_secondary_outcomes_/24919160

المؤلفون: Jonas Sundén-Cullberg, Puran Chen, Henrike Häbel, Paul Skorup, Helena Janols, Johan Rasmuson, Katarina Niward, Åse Östholm Balkhed, Katerina Chatzidionysiou, Hilmir Asgeirsson, Ola Blennow, Åsa Parke, Anna-Karin Svensson, Jagadeeswara Rao Muvva, Hans-Gustav Ljunggren, Anna-Carin Horne, Ulrika Ådén, Jan-Inge Henter, Anders Sönnerborg, Jan Vesterbacka, Piotr Nowak, Jon Lampa

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Neuroscience, Physiology, Biotechnology, Immunology, Developmental Biology, Mental Health, Infectious Diseases, Virology, +recruitment%22">xlink "> recruitment, least two points, conducted june 2020, 2020 &# 8211, +anakinra%22">xlink "> anakinra, limited degree anakinra, tocilizumab became part, significantly shorten time, randomly assigned 1, planned 195 patients, dimer ≥ 0, clinical recovery compared, ci ], uc vs anakinra, vs uc, usual care, uc alone, single dose

Relation: https://figshare.com/articles/dataset/Patient_characteristics_at_baseline_by_randomised_groups_/24919157

الاتاحة: https://doi.org/10.1371/journal.pone.0295838.t001
https://figshare.com/articles/dataset/Patient_characteristics_at_baseline_by_randomised_groups_/24919157

المؤلفون: Jonas Sundén-Cullberg, Puran Chen, Henrike Häbel, Paul Skorup, Helena Janols, Johan Rasmuson, Katarina Niward, Åse Östholm Balkhed, Katerina Chatzidionysiou, Hilmir Asgeirsson, Ola Blennow, Åsa Parke, Anna-Karin Svensson, Jagadeeswara Rao Muvva, Hans-Gustav Ljunggren, Anna-Carin Horne, Ulrika Ådén, Jan-Inge Henter, Anders Sönnerborg, Jan Vesterbacka, Piotr Nowak, Jon Lampa

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Neuroscience, Physiology, Biotechnology, Immunology, Developmental Biology, Mental Health, Infectious Diseases, Virology, +recruitment%22">xlink "> recruitment, least two points, conducted june 2020, 2020 &# 8211, +anakinra%22">xlink "> anakinra, limited degree anakinra, tocilizumab became part, significantly shorten time, randomly assigned 1, planned 195 patients, dimer ≥ 0, clinical recovery compared, ci ], uc vs anakinra, vs uc, usual care, uc alone, single dose

Relation: https://figshare.com/articles/dataset/Serious_adverse_events_by_system_organ_class_and_treatment_arm_by_study_day_29_/24919163

الاتاحة: https://doi.org/10.1371/journal.pone.0295838.t003
https://figshare.com/articles/dataset/Serious_adverse_events_by_system_organ_class_and_treatment_arm_by_study_day_29_/24919163

المؤلفون: Jonas Sundén-Cullberg, Puran Chen, Henrike Häbel, Paul Skorup, Helena Janols, Johan Rasmuson, Katarina Niward, Åse Östholm Balkhed, Katerina Chatzidionysiou, Hilmir Asgeirsson, Ola Blennow, Åsa Parke, Anna-Karin Svensson, Jagadeeswara Rao Muvva, Hans-Gustav Ljunggren, Anna-Carin Horne, Ulrika Ådén, Jan-Inge Henter, Anders Sönnerborg, Jan Vesterbacka, Piotr Nowak, Jon Lampa

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Neuroscience, Physiology, Biotechnology, Immunology, Developmental Biology, Mental Health, Infectious Diseases, Virology, +recruitment%22">xlink "> recruitment, least two points, conducted june 2020, 2020 &# 8211, +anakinra%22">xlink "> anakinra, limited degree anakinra, tocilizumab became part, significantly shorten time, randomly assigned 1, planned 195 patients, dimer ≥ 0, clinical recovery compared, ci ], uc vs anakinra, vs uc, usual care, uc alone, single dose

Relation: https://figshare.com/articles/dataset/Study_data_/24919145

الاتاحة: https://doi.org/10.1371/journal.pone.0295838.s009
https://figshare.com/articles/dataset/Study_data_/24919145

المؤلفون: Jonas Sundén-Cullberg, Puran Chen, Henrike Häbel, Paul Skorup, Helena Janols, Johan Rasmuson, Katarina Niward, Åse Östholm Balkhed, Katerina Chatzidionysiou, Hilmir Asgeirsson, Ola Blennow, Åsa Parke, Anna-Karin Svensson, Jagadeeswara Rao Muvva, Hans-Gustav Ljunggren, Anna-Carin Horne, Ulrika Ådén, Jan-Inge Henter, Anders Sönnerborg, Jan Vesterbacka, Piotr Nowak, Jon Lampa

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Neuroscience, Physiology, Biotechnology, Immunology, Developmental Biology, Mental Health, Infectious Diseases, Virology, +recruitment%22">xlink "> recruitment, least two points, conducted june 2020, 2020 &# 8211, +anakinra%22">xlink "> anakinra, limited degree anakinra, tocilizumab became part, significantly shorten time, randomly assigned 1, planned 195 patients, dimer ≥ 0, clinical recovery compared, ci ], uc vs anakinra, vs uc, usual care, uc alone, single dose

Relation: https://figshare.com/articles/figure/CONSORT_flow_diagram_/24919148

الاتاحة: https://doi.org/10.1371/journal.pone.0295838.g001
https://figshare.com/articles/figure/CONSORT_flow_diagram_/24919148

المؤلفون: Jonas Sundén-Cullberg, Puran Chen, Henrike Häbel, Paul Skorup, Helena Janols, Johan Rasmuson, Katarina Niward, Åse Östholm Balkhed, Katerina Chatzidionysiou, Hilmir Asgeirsson, Ola Blennow, Åsa Parke, Anna-Karin Svensson, Jagadeeswara Rao Muvva, Hans-Gustav Ljunggren, Anna-Carin Horne, Ulrika Ådén, Jan-Inge Henter, Anders Sönnerborg, Jan Vesterbacka, Piotr Nowak, Jon Lampa

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Neuroscience, Physiology, Biotechnology, Immunology, Developmental Biology, Mental Health, Infectious Diseases, Virology, +recruitment%22">xlink "> recruitment, least two points, conducted june 2020, 2020 &# 8211, +anakinra%22">xlink "> anakinra, limited degree anakinra, tocilizumab became part, significantly shorten time, randomly assigned 1, planned 195 patients, dimer ≥ 0, clinical recovery compared, ci ], uc vs anakinra, vs uc, usual care, uc alone, single dose

Relation: https://figshare.com/articles/figure/Ordinal_score_changes_per_treatment_allocation_/24919154

الاتاحة: https://doi.org/10.1371/journal.pone.0295838.g003
https://figshare.com/articles/figure/Ordinal_score_changes_per_treatment_allocation_/24919154