المؤلفون: Sandra Montes-Olivas, Danny Legge, Abbie Lund, Alexander G Fletcher, Ann C Williams, Lucia Marucci, Martin Homer

المصدر: PLoS Computational Biology, Vol 19, Iss 8, p e1011386 (2023)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

URL الوصول: https://doaj.org/article/bc64428b884d4479a8b56223f15161f1

المؤلفون: Alexander Greenhough, Clare Bagley, Kate J Heesom, David B Gurevich, David Gay, Mark Bond, Tracey J Collard, Chris Paraskeva, Paul Martin, Owen J Sansom, Karim Malik, Ann C Williams

المصدر: EMBO Molecular Medicine, Vol 10, Iss 11, Pp 1-13 (2018)

مصطلحات موضوعية: cancer, GPRC5A, HIF, hypoxia, YAP, Medicine (General), R5-920, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

URL الوصول: https://doaj.org/article/46c54f6455b9460fbdfd09461e4f6747

المؤلفون: Danny N. Legge, Tracey J. Collard, Ewelina Stanko, Ashley J. Hoskin, Amy K. Holt, Caroline J. Bull, Madhu Kollareddy, Jake Bellamy, Sarah Groves, Eric H. Ma, Emma Hazelwood, David Qualtrough, Borko Amulic, Karim Malik, Ann C. Williams, Nicholas Jones, Emma E. Vincent

المصدر: Molecular Metabolism, Vol 90, Iss , Pp 102037- (2024)

مصطلحات موضوعية: Colorectal cancer, Oncometabolism, Asparagine, Asparagine synthetase, Adenoma, Adenocarcinoma, Internal medicine, RC31-1245

Relation: http://www.sciencedirect.com/science/article/pii/S2212877824001686; https://doaj.org/toc/2212-8778; https://doaj.org/article/b9bf09afa6cc4ffa9c8af160884748f0

الاتاحة: https://doi.org/10.1016/j.molmet.2024.102037
https://doaj.org/article/b9bf09afa6cc4ffa9c8af160884748f0

المؤلفون: Amy K. Holt, Arafath K. Najumudeen, Tracey J. Collard, Hao Li, Laura M. Millett, Ashley J. Hoskin, Danny N. Legge, Eleanor M. H. Mortensson, Dustin J. Flanagan, Nicholas Jones, Madhu Kollareddy, Penny Timms, Matthew D. Hitchings, James Cronin, Owen J. Sansom, Ann C. Williams, Emma E. Vincent

المصدر: Cancer & Metabolism, Vol 11, Iss 1, Pp 1-19 (2023)

مصطلحات موضوعية: Colorectal cancer, Aspirin, Metabolism, Metabolic reprogramming, CB-839, Glutaminase, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Relation: https://doi.org/10.1186/s40170-023-00318-y; https://doaj.org/toc/2049-3002; https://doaj.org/article/d2b8ee6de35a474887a1c18cb634d284

الاتاحة: https://doi.org/10.1186/s40170-023-00318-y
https://doaj.org/article/d2b8ee6de35a474887a1c18cb634d284

المؤلفون: Ashley J. Hoskin, Amy K. Holt, Danny N. Legge, Tracey J. Collard, Ann C. Williams, Emma E. Vincent

المصدر: Exploration of Targeted Anti-tumor Therapy, Vol 4, Iss 4, Pp 600-615 (2023)

مصطلحات موضوعية: aspirin, cancer metabolism, metabolic hallmark, colorectal cancer, cancer prevention, nonsteroidal anti-inflammatory drugs, adjuvant for therapy, anti-tumour, Internal medicine, RC31-1245

Relation: https://www.explorationpub.com/Journals/etat/Article/1002155; https://doaj.org/toc/2692-3114; https://doaj.org/article/ea03b3ba9b3d41bda037c67e820ff463

الاتاحة: https://doi.org/10.37349/etat.2023.00155
https://doaj.org/article/ea03b3ba9b3d41bda037c67e820ff463

المؤلفون: Philip C. Haycock, Maria Carolina Borges, Kimberley Burrows, Rozenn N. Lemaitre, Stephen Burgess, Nikhil K. Khankari, Konstantinos K. Tsilidis, Tom R. Gaunt, Gibran Hemani, Jie Zheng, Therese Truong, Brenda M. Birmann, Tracy OMara, Amanda B. Spurdle, Mark M. Iles, Matthew H. Law, Susan L. Slager, Fatemeh Saberi Hosnijeh, Daniela Mariosa, Michelle Cotterchio, James R. Cerhan, Ulrike Peters, Stefan Enroth, Puya Gharahkhani, Loic Le Marchand, Ann C. Williams, Robert C. Block, Christopher I. Amos, Rayjean J. Hung, Wei Zheng, Marc J. Gunter, George Davey Smith, Caroline Relton, Richard M. Martin, Nathan Tintle, Terri Rice, Iona Cheng, Mark Jenkins, Steve Gallinger, Alex J. Cornish, Amit Sud, Jayaram Vijayakrishnan, Margaret Wrensch, Mattias Johansson, Aaron D. Norman, Alison Klein, Alyssa Clay-Gilmour, Andre Franke, Andres V. Ardisson Korat, Bill Wheeler, Björn Nilsson, Caren Smith, Chew-Kiat Heng, Ci Song, David Riadi, Elizabeth B. Claus, Eva Ellinghaus, Evgenia Ostroumova, Hosnijeh, Florent de Vathaire, Giovanni Cugliari, Giuseppe Matullo, Irene Oi-Lin Ng, Jeanette E. Passow, Jia Nee Foo, Jiali Han, Jianjun Liu, Jill Barnholtz-Sloan, Joellen M. Schildkraut, John Maris, Joseph L. Wiemels, Kari Hemminki, Keming Yang, Lambertus A. Kiemeney, Lang Wu, Laufey Amundadottir, Marc-Henri Stern, Marie-Christine Boutron, Mark Martin Iles, Mark P. Purdue, Martin Stanulla, Melissa Bondy, Mia Gaudet, Lenha Mobuchon, Nicola J. Camp, Pak Chung Sham, Pascal Guénel, Paul Brennan, Philip R. Taylor, Quinn Ostrom, Rachael Stolzenberg-Solomon, Rajkumar Dorajoo, Richard Houlston, Robert B. Jenkins, Sharon Diskin, Sonja I. Berndt, Spiridon Tsavachidis, Stephen J. Channock, Tabitha Harrison, Tessel Galesloot, Ulf Gyllensten, Vijai Joseph, Y. Shi, Wenjian Yang, Yi Lin, Stephen K. Van Den Eeden

المصدر: EBioMedicine, Vol 91, Iss , Pp 104510- (2023)

مصطلحات موضوعية: Mendelian randomization, Cancer risk, Polyunsaturated fatty acids, Omega 3, Omega 6, Delta-5 desaturase, Medicine, Medicine (General), R5-920

Relation: http://www.sciencedirect.com/science/article/pii/S2352396423000750; https://doaj.org/toc/2352-3964; https://doaj.org/article/89940d7363ce43c781ea8d5c3c0a79fa

الاتاحة: https://doi.org/10.1016/j.ebiom.2023.104510
https://doaj.org/article/89940d7363ce43c781ea8d5c3c0a79fa

المؤلفون: Aayah Nounu, Rebecca C. Richmond, Isobel D. Stewart, Praveen Surendran, Nicholas J. Wareham, Adam Butterworth, Stephanie J. Weinstein, Demetrius Albanes, John A. Baron, John L. Hopper, Jane C. Figueiredo, Polly A. Newcomb, Noralane M. Lindor, Graham Casey, Elizabeth A. Platz, Loïc Le Marchand, Cornelia M. Ulrich, Christopher I. Li, Fränzel J. B. van Dujinhoven, Andrea Gsur, Peter T. Campbell, Víctor Moreno, Pavel Vodicka, Ludmila Vodickova, Efrat Amitay, Elizabeth Alwers, Jenny Chang-Claude, Lori C. Sakoda, Martha L. Slattery, Robert E. Schoen, Marc J. Gunter, Sergi Castellví-Bel, Hyeong-Rok Kim, Sun-Seog Kweon, Andrew T. Chan, Li Li, Wei Zheng, D. Timothy Bishop, Daniel D. Buchanan, Graham G. Giles, Stephen B. Gruber, Gad Rennert, Zsofia K. Stadler, Tabitha A. Harrison, Yi Lin, Temitope O. Keku, Michael O. Woods, Clemens Schafmayer, Bethany Van Guelpen, Steven Gallinger, Heather Hampel, Sonja I. Berndt, Paul D. P. Pharoah, Annika Lindblom, Alicja Wolk, Anna H. Wu, Emily White, Ulrike Peters, David A. Drew, Dominique Scherer, Justo Lorenzo Bermejo, Hermann Brenner, Michael Hoffmeister, Ann C. Williams, Caroline L. Relton

المصدر: Nutrients, Vol 13, Iss 11, p 4164 (2021)

مصطلحات موضوعية: salicylic acid, aspirin, colorectal cancer, Mendelian randomization, Nutrition. Foods and food supply, TX341-641

Relation: https://www.mdpi.com/2072-6643/13/11/4164; https://doaj.org/toc/2072-6643; https://doaj.org/article/e30a5ff9584c4ac6a79691fbd1a22a9a

الاتاحة: https://doi.org/10.3390/nu13114164
https://doaj.org/article/e30a5ff9584c4ac6a79691fbd1a22a9a

المؤلفون: Danny N. Legge, Alex P. Shephard, Tracey J. Collard, Alexander Greenhough, Adam C. Chambers, Richard W. Clarkson, Christos Paraskeva, Ann C. Williams

المصدر: Disease Models & Mechanisms, Vol 12, Iss 3 (2019)

مصطلحات موضوعية: NF-kappaB, NF-κB, LGR5, ASCL2, Wnt, Spheroid, BCL3, Medicine, Pathology, RB1-214

وصف الملف: electronic resource

Relation: http://dmm.biologists.org/content/12/3/dmm037697; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411

URL الوصول: https://doaj.org/article/cd9fde3343ff408689e9cb006bd97664

المؤلفون: Rhys Morgan, Jenna Ridsdale, Megan Payne, Kate J Heesom, Marieangela C Wilson, Andrew Davidson, Alexander Greenhough, Sara Davies, Ann C Williams, Allison Blair, Marian L Waterman, Alex Tonks, Richard L Darley

مصطلحات موضوعية: ß-Catenin, Wnt Signaling, LEF-1, Myeloid, Leukemia, Interactome

Relation: 10779/uos.23464883.v2; https://figshare.com/articles/journal_contribution/LEF-1_drives_aberrant_-catenin_nuclear_localization_in_myeloid_leukemia_cells/23464883

الاتاحة: https://figshare.com/articles/journal_contribution/LEF-1_drives_aberrant_-catenin_nuclear_localization_in_myeloid_leukemia_cells/23464883

المؤلفون: Rhys G. Morgan, Jenna Ridsdale, Megan Payne, Kate J. Heesom, Marieangela C. Wilson, Andrew Davidson, Alexander Greenhough, Sara Davies, Ann C. Williams, Allison Blair, Marian L. Waterman, Alex Tonks, Richard L. Darley

المصدر: Haematologica, Vol 104, Iss 7 (2019)

مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5

Relation: https://haematologica.org/article/view/8967; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721; https://doaj.org/article/67f282a8773c4e4da92b6fe97861268a

الاتاحة: https://doi.org/10.3324/haematol.2018.202846
https://doaj.org/article/67f282a8773c4e4da92b6fe97861268a

المؤلفون: Sandra Montes-Olivas, Danny Legge, Abbie Lund, Alexander G. Fletcher, Ann C. Williams, Lucia Marucci, Martin Homer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::79c2465167792f8490c255d96ffdd069
https://doi.org/10.1101/2022.12.08.519603

المؤلفون: Danny Legge, Amy K Holt, Caroline J Bull, Tracey Collard, Madhu Kollareddy, Jake Bellamy, Sarah Groves, Eric H Ma, Emma Hazelwood, David Qualtrough, Borko Amulic, Karim Malik, Ann C Williams, Nicholas Jones, Emma E Vincent

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f7d5e5c0b2d28216b4d280f61f900cc7
https://doi.org/10.15252/rc.2022178417

المؤلفون: Christopher Parker, Adam C. Chambers, Dustin J. Flanagan, Jasmine Wing Yu Ho, Tracey J. Collard, Greg Ngo, Duncan M. Baird, Penny Timms, Rhys G. Morgan, Owen J. Sansom, Ann C. Williams

المصدر: Parker, C, Chambers, A C, Flanagan, D J, Ho, J W Y, Collard, T J, Ngo, G, Baird, D M, Timms, P, Morgan, R G, Sansom, O J & Williams, A C 2022, ' BCL-3 loss sensitises colorectal cancer cells to DNA damage by targeting homologous recombination ', DNA repair, vol. 115, 103331 . https://doi.org/10.1016/j.dnarep.2022.103331

مصطلحات موضوعية: Mice, Cell Line, Tumor, Animals, Humans, Colorectal Neoplasms/drug therapy, Cell Biology, Cisplatin, Cisplatin/therapeutic use, Colorectal Neoplasms, Homologous Recombination, Molecular Biology, Biochemistry, DNA Damage

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b79364554502afec628f6dd8f54280

المؤلفون: M G Thomas, Paul D. White, David E. Messenger, Adam C. Chambers, Ann C. Williams, Steven William Dixon

المصدر: The British Journal of Surgery

مصطلحات موضوعية: Adult, Male, Colorectal cancer, Population, MEDLINE, Disease, 030230 surgery, Young Adult, 03 medical and health sciences, Age Distribution, 0302 clinical medicine, Humans, Medicine, Registries, Age of Onset, Sex Distribution, Young adult, education, education.field_of_study, business.industry, Incidence, Incidence (epidemiology), Cancer, Original Articles, Middle Aged, medicine.disease, England, Population Surveillance, 030220 oncology & carcinogenesis, Lower GI, Female, Original Article, Surgery, Colorectal Neoplasms, business, Cohort study, Demography

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5da0a3f792739f4971c83746930e0e
https://doi.org/10.1002/bjs.11486

المؤلفون: Peter A Johnson, Sara Menegatti, Adam C Chambers, Dominic Alibhai, Tracey J Collard, Ann C Williams, Hagan Bayley, Adam W Perriman

المصدر: Biofabrication. 15(1)

مصطلحات موضوعية: Biomaterials, Oxaliplatin, Spheroids, Cellular, Biomedical Engineering, Bioprinting, Humans, Bioengineering, General Medicine, Fluorouracil, Colorectal Neoplasms, Biochemistry, Biotechnology, Cell Line

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acac3d9e157101f46ebeb69bfc20cc80
https://pubmed.ncbi.nlm.nih.gov/36321254

المؤلفون: Danny N. Legge, Amy K. Holt, Caroline J. Bull, Tracey J. Collard, Madhu Kollareddy, Jake Bellamy, Sarah Groves, Eric H. Ma, Emma Hazelwood, David Qualtrough, Borko Amulic, Karim Malik, Ann C. Williams, Nicholas Jones, Emma E. Vincent

مصطلحات موضوعية: digestive system diseases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::13803235ac78dcb8545a11cdcae5c234
https://doi.org/10.1101/2022.03.23.485483

المؤلفون: Danny Legge, Ann C. Williams, Tracey J Collard, Christopher Parker, Adam C. Chambers, Penny Timms

المصدر: Carcinogenesis
Legge, D N, Chambers, A C, Parker, C T, Timms, P, Collard, T J & Williams, A C 2020, ' The role of B-Cell Lymphoma-3 (BCL-3) in enabling the hallmarks of cancer : implications for the treatment of colorectal carcinogenesis ', Carcinogenesis . https://doi.org/10.1093/carcin/bgaa003

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Colorectal cancer, Carcinogenesis, AcademicSubjects/MED00710, colorectal cancer, lymphoma, Review, Proto-Oncogene Mas, Metastasis, 03 medical and health sciences, 0302 clinical medicine, B-Cell Lymphoma 3 Protein, Cell Plasticity, medicine, cancer, Humans, Neoplasm Invasiveness, B-cell lymphoma, Cell Proliferation, business.industry, NF-kappa B, Cancer, bcl3 protein, General Medicine, medicine.disease, Prognosis, Lymphoma, Gene Expression Regulation, Neoplastic, 030104 developmental biology, The Hallmarks of Cancer, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, Neoplastic Stem Cells, Neoplasm Recurrence, Local, business, Colorectal Neoplasms, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ba46ce8f7fd2b1f3897fe0e180f101
http://europepmc.org/articles/PMC7221501

المؤلفون: David Qualtrough, Phil Rees, Beverley Speight, Ann C. Williams, Christos Paraskeva

المصدر: Cancers, Vol 7, Iss 3, Pp 1885-1899 (2015)

مصطلحات موضوعية: colorectal cancer, Wnt signalling, hedgehog signalling, E-cadherin, cyclopamine, β-catenin/Tcf, EMT, invasion, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Relation: http://www.mdpi.com/2072-6694/7/3/0867; https://doaj.org/toc/2072-6694; https://doaj.org/article/02c9ee4e8d6342b3b3d9f523df547a10

الاتاحة: https://doi.org/10.3390/cancers7030867
https://doaj.org/article/02c9ee4e8d6342b3b3d9f523df547a10

المؤلفون: Alexander Greenhough, Chris Paraskeva, Ann C. Williams

المصدر: EBioMedicine, Vol 2, Iss 2, Pp 105-106 (2015)

مصطلحات موضوعية: Medicine, Medicine (General), R5-920

Relation: http://www.sciencedirect.com/science/article/pii/S2352396415000390; https://doaj.org/toc/2352-3964; https://doaj.org/article/6bc857793798470aaa8e0a1606e52306

الاتاحة: https://doi.org/10.1016/j.ebiom.2015.01.016
https://doaj.org/article/6bc857793798470aaa8e0a1606e52306

المؤلفون: Christopher Parker, Greg H.P. Ngo, Duncan M. Baird, Owen J. Sansom, Dustin J. Flanagan, Ann C. Williams, Adam C. Chambers, Rhys G. Morgan, Tracey J Collard, Penny Timms

مصطلحات موضوعية: Cisplatin, chemistry.chemical_compound, chemistry, DNA damage, Poly ADP ribose polymerase, PARP inhibitor, RAD51, Cancer research, medicine, Homologous recombination, Double Strand Break Repair, Olaparib, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::743f9ae6fd320dab2383458578eecc39
https://doi.org/10.1101/2021.08.03.454995