المؤلفون: Audrey D McConnell, Minjee Do, Tamlyn Y Neben, Vladimir Spasojevic, Josh MacLaren, Andy P Chen, Laurence Altobell, John L Macomber, Ashley D Berkebile, Robert A Horlick, Peter M Bowers, David J King

المصدر: PLoS ONE, Vol 7, Iss 11, p e49458 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3498135?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/b9ba0a64e8aa4557b73a1c4372b71869

المؤلفون: Ashley D. Berkebile, Audrey D. McConnell, Peter Bowers, Joseph C. Sheffer, John L. Macomber, David J. King, Steven S. Neben, Andy P. Chen, Robert A. Horlick, Irina P. Krapf, Vladimir Spasojevich

المصدر: Protein Engineering Design and Selection. 26:151-164

مصطلحات موضوعية: Models, Molecular, Hot Temperature, Recombinant Fusion Proteins, Antibody Affinity, Mutagenesis (molecular biology technique), Somatic hypermutation, Bioengineering, Plasma protein binding, Protein Engineering, Biochemistry, Affinity maturation, Mice, Antigen, Antibody Specificity, Animals, Humans, Transition Temperature, Computer Simulation, Protein Interaction Domains and Motifs, Amino Acid Sequence, Molecular Biology, Levivirus, Protein Unfolding, biology, Protein Stability, Chemistry, Protein engineering, Complementarity Determining Regions, In vitro, Kinetics, HEK293 Cells, Amino Acid Substitution, Immunoglobulin G, Mutagenesis, Site-Directed, biology.protein, Cystine, Capsid Proteins, Directed Molecular Evolution, Antibody, Cell Surface Display Techniques, Monte Carlo Method, Protein Binding, Single-Chain Antibodies, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7315cc105800b3843017cde32deb94dc
https://doi.org/10.1093/protein/gzs090

المؤلفون: Laurence Altobell, Trevin Holland, Betty F. Wu, Geoffrey L. Tomlinson, Xue Zhang, Ashley D. Berkebile, Betty Chau, Rachelle M. Toobian, Robert A. Horlick, Steven S. Neben, John L. Macomber, David J. King, Jennifer L. Dalton, Tamlyn Y. Neben, Andy P. Chen, Irina P. Krapf, Heather A. Jones, Audrey D. McConnell, William J. Boyle, Peter Bowers

المصدر: Proceedings of the National Academy of Sciences. 108:20455-20460

مصطلحات موضوعية: Glycosylation, Molecular Sequence Data, Somatic hypermutation, medicine.disease_cause, Antibodies, Immunoglobulin G, Nerve Growth Factor, medicine, Humans, Amino Acid Sequence, B cell, B-Lymphocytes, Mutation, Multidisciplinary, Sequence Homology, Amino Acid, biology, Cell Membrane, HEK 293 cells, Cytidine deaminase, Biological Sciences, Flow Cytometry, Acquired immune system, Molecular biology, Cell biology, Kinetics, HEK293 Cells, medicine.anatomical_structure, Immunoglobulin M, biology.protein, Somatic Hypermutation, Immunoglobulin, Antibody

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e75ec7744f8b52feb415f2e0ec09038
https://doi.org/10.1073/pnas.1114010108

المؤلفون: Yen-Ju Chen, Andy P. Chen, Geoffrey Chang, Che Ma, Samantha S. Lieu, Owen Pornillos

المصدر: Proceedings of the National Academy of Sciences. 104:18999-19004

مصطلحات موضوعية: Models, Molecular, Protein Conformation, Stereochemistry, Dimer, Molecular Sequence Data, Fluorescence Polarization, Crystallography, X-Ray, Antiparallel (biochemistry), Antiporters, chemistry.chemical_compound, Onium Compounds, Organophosphorus Compounds, Protein structure, Amino Acid Sequence, Small multidrug resistance protein, Selenomethionine, Peptide sequence, Multidisciplinary, Escherichia coli Proteins, Biological Sciences, Recombinant Proteins, Transmembrane domain, Crystallography, Monomer, Dual topology, chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c598e857eaa68cab95688b35e25e6920
https://doi.org/10.1073/pnas.0709387104

المؤلفون: Owen Pornillos, Yen-Ju Chen, Geoffrey Chang, Andy P. Chen

المصدر: Science. 310:1950-1953

مصطلحات موضوعية: Multidisciplinary, Protein Conformation, Stereochemistry, Escherichia coli Proteins, Dimer, Protein subunit, Membrane Proteins, Biological Transport, Transporter, Biology, Crystallography, X-Ray, Antiparallel (biochemistry), Antiporters, chemistry.chemical_compound, Onium Compounds, Organophosphorus Compounds, Protein structure, Membrane, chemistry, Drug Resistance, Multiple, Bacterial, Escherichia coli, Inner membrane, Efflux

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::988c08e11dc23dc9be7c6a21640047fd
https://doi.org/10.1126/science.1119776

المؤلفون: Laurence Altobell, Robert A. Horlick, Ashley D. Berkebile, Vladimir Spasojevic, Audrey D. McConnell, Peter Bowers, Tamlyn Y. Neben, David J. King, Josh MacLaren, John L. Macomber, Andy P. Chen, Minjee Do

المصدر: PLoS ONE
PLoS ONE, Vol 7, Iss 11, p e49458 (2012)

مصطلحات موضوعية: Lymphoid Tissue, Immune Cells, Immunology, Complement System, Somatic hypermutation, lcsh:Medicine, Immunoglobulins, Autoimmunity, Biology, Immunoglobulin light chain, Antibodies, Monoclonal, Humanized, Biochemistry, Affinity maturation, Mice, Cytidine Deaminase, Drug Discovery, Animals, Humans, lcsh:Science, Multidisciplinary, Immune System Proteins, HEK 293 cells, lcsh:R, Immunity, Proteins, Complement C5, Cytidine deaminase, Cell sorting, Flow Cytometry, Molecular biology, Immunizations, Recombinant Proteins, HEK293 Cells, Immune System, biology.protein, Immunoglobulin heavy chain, lcsh:Q, Immunoglobulin Light Chains, Somatic Hypermutation, Immunoglobulin, Antibody, Immunoglobulin Heavy Chains, Spleen, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c564c395749b6f3cb91ec0b66656aef
http://europepmc.org/articles/PMC3498135

المؤلفون: Geoffrey Chang, Christopher B. Roth, Christopher L. Reyes, Owen Pornillos, Yen-Ju Chen, Andy P. Chen

المصدر: Science. 314:1875-1875

مصطلحات موضوعية: Multidisciplinary

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f4cc592663e238b2a43eb9f564a2646e
https://doi.org/10.1126/science.314.5807.1875b