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1Academic Journal
المؤلفون: Andrew Kleinberg, Yuan Mao, Ning Li
المصدر: mAbs, Vol 16, Iss 1 (2024)
مصطلحات موضوعية: Acidic digestion, cysteine alkylation, disulfide scrambling, non-reduced peptide mapping, thiol-disulfide exchange, β-elimination, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
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2
المؤلفون: Ning Li, Andrew Kleinberg, Yuan Mao
المصدر: Analytical Chemistry. 92:9682-9690
مصطلحات موضوعية: Biological Products, Chromatography, medicine.drug_class, Chemistry, Antibodies, Monoclonal, Reproducibility of Results, Monoclonal antibody, Mass spectrometry, Tandem mass tag, Peptide Mapping, Sensitivity and Specificity, Analytical Chemistry, Targeted mass spectrometry, Tandem Mass Spectrometry, Reagent, Forced degradation, medicine, Posttranslational modification, Humans, Isobaric process, Amino Acid Sequence, Peptides, Protein Processing, Post-Translational, Chromatography, Liquid
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3
المؤلفون: Qiangwei Xia, Andrew Kleinberg, Yuan Mao, Lichao Zhang, Ning Li, Thomas J. Daly
المصدر: mAbs
مصطلحات موضوعية: Spectrometry, Mass, Electrospray Ionization, Electrospray, medicine.drug_class, medicine.medical_treatment, Immunology, Monoclonal antibody, Tandem mass spectrometry, Peptide Mapping, law.invention, Mice, 03 medical and health sciences, 0302 clinical medicine, Protein sequencing, Sequence Analysis, Protein, law, Report, TriVersa NanoMate®, medicine, Animals, Aspartic Acid Endopeptidases, Humans, Immunology and Allergy, Bovine serum albumin, Monoclonal antibody sequencing, 030304 developmental biology, 0303 health sciences, Protease, Edman degradation, biology, Chemistry, Antibodies, Monoclonal, digestion on electrospray emitter, Nanostructures, protease XIII, Aspergillus, Biochemistry, Immunoglobulin G, 030220 oncology & carcinogenesis, Proteolysis, sequence coverage, Recombinant DNA, biology.protein
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4
المؤلفون: Yuan Mao, Yunlong Zhao, Ning Li, Andrew Kleinberg, Shivkumar Raidas
المصدر: Analytical chemistry. 92(13)
مصطلحات موضوعية: Spectrometry, Mass, Electrospray Ionization, Chromatography, Chemistry, Electrospray ionization, 010401 analytical chemistry, Glycine, Signal-To-Noise Ratio, 010402 general chemistry, Mass spectrometry, Antibodies, Monoclonal, Humanized, 01 natural sciences, 0104 chemical sciences, Analytical Chemistry, Characterization (materials science), chemistry.chemical_compound, Biopharmaceutical, Liquid chromatography–mass spectrometry, Phase (matter), Trifluoroacetic acid, Humans, Trifluoroacetic Acid, Peptides, Chromatography, High Pressure Liquid
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5
المؤلفون: Seth A. Young, Andrew Kleinberg, Jeremy D. Owens
المصدر: Geological Society of America Abstracts with Programs.
مصطلحات موضوعية: Ireviken event, Paleontology, Extinction, Laurentia, Geology
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6
المؤلفون: David Epstein, Kam W. Siu, Earl W. May, Andrew Kleinberg, Prafulla C. Gokhale, Mark J. Mulvihill, Ryan Schulz, Jonathan A. Pachter, Meizhong Jin, Mridula Kadalbajoo, Kenneth Foreman, Jennifer Kahler, Mark Bittner, Brenda A. Petronella, Andy Cooke, Robert A. Wild
المصدر: ACS Medicinal Chemistry Letters. 4:627-631
مصطلحات موضوعية: Chemistry, medicine.medical_treatment, Organic Chemistry, Bioinformatics, Biochemistry, Small molecule, In vitro, Receptor–ligand kinetics, Insulin-like growth factor, Drug Discovery, Biophysics, medicine, Tumor growth inhibition, Receptor
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7
المؤلفون: Andrew P. Crew, Meizhong Jin, Kristen Michelle Mulvihill, Mark J. Mulvihill, David Epstein, Qun-Sheng Ji, Shripad V. Bhagwat, Mridula Kadalbajoo, Andrew Cooke, Josef A. Rechka, Jonathan A. Pachter, Mark Bittner, Kam W. Siu, Yan Yao, Jing Wang, April Thelemann, Andrew Kleinberg
المصدر: Bioorganic & Medicinal Chemistry Letters. 23:979-984
مصطلحات موضوعية: Pyrazine, Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, Pharmacology, Biochemistry, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Pharmacokinetics, Jing wang, Drug Discovery, Animals, Humans, Structure–activity relationship, Protein Kinase Inhibitors, Molecular Biology, Virtual screening, Organic Chemistry, Imidazoles, Protein-Tyrosine Kinases, Bioavailability, chemistry, Pyrazines, Molecular Medicine, Drug metabolism
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8
المؤلفون: Dan Sherman, Pawan Rastogi, An-Hu Li, Andrew Kleinberg, Ti Wang, Mark J. Mulvihill, Anthony Nigro, Heather Coate, Kristen Michelle Mulvihill, Andrew P. Crew, Mridula Kadalbajoo, Kam W. Siu, Ayako Honda, Radoslaw Laufer, David J. Beard, Arno G. Steinig, Doug Werner
المصدر: Synthesis. 2010:1678-1686
مصطلحات موضوعية: chemistry.chemical_compound, Aqueous solution, chemistry, Scope (project management), Organic Chemistry, Quinoline, Organic chemistry, Catalysis
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9
المؤلفون: Jeremy D. Owens, Andrew Kleinberg, Seth A. Young
المصدر: Geological Society of America Abstracts with Programs.
مصطلحات موضوعية: Extinction event, Paleontology, Geology
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10
المؤلفون: Darlene Romashko, James G. Tarrant, Felix Weng, Keith R. Hornberger, Matthew R. Medeiros, Andrew Kleinberg, Peter Meyn, Dan Maarten Berger, Mark Albertella, William Peick, An-Hu Li, Mark Bittner, Jing Wang, Hanqing Dong, Paul Maresca, Mark J. Mulvihill, Earl W. May, Wilde Victoria Lynn, Kam W. Siu, Brianna Tokar, Michael Tanowitz, Michael J. Gray, Andrew P. Crew, Andrew Cooke
المصدر: Bioorganicmedicinal chemistry letters. 23(16)
مصطلحات موضوعية: Stereochemistry, Pyridines, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, chemistry.chemical_compound, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, Neoplasms, Drug Discovery, Pyridine, Potency, Animals, Humans, Amines, Enzyme Inhibitors, Furans, Molecular Biology, Molecular Structure, Chemistry, Organic Chemistry, MAP Kinase Kinase Kinases, Xenograft Model Antitumor Assays, Enzyme Activation, Drug Design, Molecular Medicine
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11
المؤلفون: Yue Peng, Hanqing Dong, Xin Chen, Arno G. Steinig, Darla Landfair, David Epstein, Ryan Schulz, Paula A. Tavares-Greco, Meizhong Jin, Andy Cooke, Jonathan A. Pachter, Jen Workman, Jennifer Kahler, Kathryn M. Stolz, Christine Mantis, Linda Crew, Ti Wang, Mark J. Mulvihill, Mridula Kadalbajoo, Jing Wang, Maryland Franklin, Caterina Ferraro, Robert A. Wild, Julie Kan, Prafulla C. Gokhale, Mark Albertella, Roy Turton, An-Hu Li, Mark Bittner, Andrew Kleinberg
المصدر: Bioorganicmedicinal chemistry letters. 23(15)
مصطلحات موضوعية: medicine.drug_class, Cell Survival, Pyridines, Clinical Biochemistry, Transplantation, Heterologous, Pharmaceutical Science, Mice, Nude, Antineoplastic Agents, Pharmacology, Biochemistry, Tyrosine-kinase inhibitor, Rats, Sprague-Dawley, Mice, Structure-Activity Relationship, In vivo, Cell Line, Tumor, Neoplasms, Drug Discovery, medicine, Transferase, Structure–activity relationship, Animals, Humans, Phosphorylation, Molecular Biology, Protein Kinase Inhibitors, Kinase, Chemistry, Organic Chemistry, Receptor Protein-Tyrosine Kinases, Biological activity, Hydrogen-Ion Concentration, Proto-Oncogene Proteins c-met, Rats, Transplantation, Cell culture, Mutation, Molecular Medicine, Female, Half-Life
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12
المؤلفون: Darla Landfair, Prafulla C. Gokhale, Qun-Sheng Ji, Robert A. Wild, Kristen Michelle Mulvihill, Meizhong Jin, Kenneth Foreman, Hanqing Dong, Gilda Mak, Andrew Kleinberg, Andy Cooke, Mark J. Mulvihill, Matthew O'Connor, Mark Bittner, Yan Yao, Kam W. Siu, Maryland Rosenfeld-Franklin, Jonathan A. Pachter
المصدر: Bioorganicmedicinal chemistry letters. 21(4)
مصطلحات موضوعية: medicine.medical_treatment, Clinical Biochemistry, Transplantation, Heterologous, Pharmaceutical Science, Antineoplastic Agents, Pharmacology, Biochemistry, Receptor, IGF Type 1, Insulin-like growth factor, Mice, Structure-Activity Relationship, Growth factor receptor, In vivo, Neoplasms, Drug Discovery, medicine, Structure–activity relationship, Moiety, Animals, Molecular Biology, Protein Kinase Inhibitors, Insulin-like growth factor 1 receptor, Chemistry, Organic Chemistry, Imidazoles, Transplantation, Pyrazines, Molecular Medicine, Benzimidazoles, Signal transduction
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13
المؤلفون: Andrew Kleinberg, Prafulla C. Gokhale, Kathryn M. Stolz, Yan Yao, Andy Cooke, An-Hu Li, Douglas S. Werner, Robert A. Wild, Darla Landfair, Arno G. Steinig, Earl W. May, Mark Bittner, Elizabeth Buck, Hanqing Dong, Mark J. Mulvihill, Jonathan A. Pachter, Radoslaw Laufer, Mridula Kadalbajoo, Lixin Feng, Kam W. Siu, Kenneth Foreman, Meizhong Jin
مصطلحات موضوعية: biology, business.industry, Organic Chemistry, Dual inhibitor, Biological activity, Pharmacology, Biochemistry, chemistry.chemical_compound, Insulin receptor, chemistry, In vivo, Drug Discovery, biology.protein, Medicine, business, Receptor, Tumor xenograft, Triazine
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14
المؤلفون: Andrew P. Crew, Shripad V. Bhagwat, Mark J. Mulvihill, David Epstein, Andrew Cooke, Yan Yao, Mark Bittner, Qun-Sheng Ji, Meizhong Jin, Andrew Kleinberg, Jing Wang, April Thelemann, Josef A. Rechka, Jonathan A. Pachter, Kam W. Siu, Mridula Kadalbajoo, Kristen Michelle Mulvihill
المصدر: Cancer Research. 73:2463-2463
مصطلحات موضوعية: Cancer Research, Virtual screening, Kinase, business.industry, Cancer, Pharmacology, medicine.disease, Androgen receptor, Prostate cancer, Oncology, In vivo, Medicine, business, Protein kinase B, Tyrosine kinase
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15
المؤلفون: Prafulla C. Gokhale, Darla Landfair, Julie Kan, Jonathan A. Pachter, Andrew Kleinberg, Meizhong Jin, Ti Wang, Mark J. Mulvihill, Arno G. Steinig, Yue Peng, Roy Turton, An-Hu Li, Kathryn M. Stolz Gavagan, Siobhan McCormack, Hanqing Dong, Jing Wang, Maryland Franklin, Mark Bittner, Linda Castaldo, Jen Kahler, David Epstein, Paula A. Tavares-Greco, Andy Cooke, Robert A. Wild, Mark Albertella
المصدر: Cancer Research. 72:2915-2915
مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, biology, Kinase, business.industry, Autophosphorylation, Pharmacology, Receptor tyrosine kinase, Oncology, biology.protein, Medicine, Phosphorylation, STAT3, Autocrine signalling, business, Protein kinase B
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16
المؤلفون: Prafulla C. Gokhale, Kathryn M. Stolz, Mridula Kadalbajoo, Yan Yao, Kenneth Foreman, Arno G. Steinig, Lixing Feng, Mark J. Mulvihill, Earl W. May, Andrew Kleinberg, An-Hu Li, Meizhong Jin, Mark Bittner, Radoslaw Laufer, Darla Landfair, Elizabeth Buck, Hanqing Dong, Douglas S. Werner, Kam W. Siu, Jonathan A. Pachter, Robert A. Wild, Andy Cooke
المصدر: Cancer Research. 72:3900-3900
مصطلحات موضوعية: Cancer Research, Linsitinib, biology, Drug discovery, Chemistry, Pharmacology, medicine.disease_cause, Small molecule, chemistry.chemical_compound, Insulin receptor, Oncology, In vivo, medicine, biology.protein, Signal transduction, Receptor, Carcinogenesis
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