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المؤلفون: Carol L. Williams, Alexander C. Mackinnon, Jian Huang, Ellen L. Lorimer, Xiuxu Chen, Nathan J. Schuld, Carmen Bergom, Andrew D. Hauser
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المؤلفون: Carol L. Williams, Alexander C. Mackinnon, Jian Huang, Ellen L. Lorimer, Xiuxu Chen, Nathan J. Schuld, Carmen Bergom, Andrew D. Hauser
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المؤلفون: Emily A. Vucic, Craig Ramirez, Dafna Bar-Sagi, Andrew D. Hauser
المصدر: Nature
مصطلحات موضوعية: 0301 basic medicine, Vacuolar Proton-Translocating ATPases, Membrane ruffling, Carcinogenesis, Mice, Nude, RAC1, Oncogene Protein p21(ras), Article, Binge Drinking, Mice, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Neoplasms, Extracellular, Animals, V-ATPase, Humans, Protein kinase A, Adenosine Triphosphatases, Multidisciplinary, Cell growth, Chemistry, Sodium-Bicarbonate Symporters, Cell Membrane, Cyclic AMP-Dependent Protein Kinases, Cell biology, Bicarbonates, Cholesterol, 030104 developmental biology, 030220 oncology & carcinogenesis, Pinocytosis, Female, Signal transduction, Intracellular, Signal Transduction
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المؤلفون: Stephen T. Joy, Paramjit S. Arora, Andrew D. Hauser, Daniel Yoo, Dafna Bar-Sagi
المصدر: ACS Chem Biol
مصطلحات موضوعية: 0301 basic medicine, Peptidomimetic, Protein Conformation, Computational biology, Ligands, 01 natural sciences, Biochemistry, Biophysical Phenomena, Article, 03 medical and health sciences, Non-competitive inhibition, Drug Delivery Systems, Cell Line, Tumor, Humans, Protein Interaction Maps, 010405 organic chemistry, Chemistry, food and beverages, General Medicine, 0104 chemical sciences, 030104 developmental biology, Covalent bond, Drug Design, Proteolysis, ras Proteins, Molecular Medicine, Peptidomimetics, Signal Transduction
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المؤلفون: Andrew D. Hauser, Ishan Roy, Jessica M. Wilson, Carol L. Williams, Michael B. Dwinell, Noah P. Zimmerman
المصدر: Molecular Carcinogenesis. 54:203-215
مصطلحات موضوعية: Cancer Research, RHOA, Forskolin, Cilostamide, biology, Cell growth, Phosphodiesterase, Cell migration, chemistry.chemical_compound, chemistry, biology.protein, Cancer research, Protein kinase A, Molecular Biology, RhoC GTP-Binding Protein
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المؤلفون: Andrew D. Hauser, Ellen L. Lorimer, Tracy J. Berg, Adam J. Gastonguay, Nathan J. Schuld, Carol L. Williams
المصدر: Cancer Biology & Therapy. 13:647-656
مصطلحات موضوعية: rac1 GTP-Binding Protein, Cancer Research, Lung Neoplasms, Transcription, Genetic, Angiogenesis, Cell, RAC1, Biology, Cell Movement, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Nitriles, medicine, Humans, Gene silencing, Gene Silencing, Sulfones, Lung cancer, Cell Proliferation, Pharmacology, Cell growth, Cell Cycle, NF-kappa B, Cell migration, Cell cycle, medicine.disease, Pyrimidines, medicine.anatomical_structure, Oncology, Aminoquinolines, Cancer research, Molecular Medicine, Research Paper
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المؤلفون: Jacek Zielonka, Balaraman Kalyanaraman, Carol L. Williams, Andrew D. Hauser, Joy Joseph, Gang Cheng, Sonia L. Sugg, Donna McAllister, J. Jordi Rowe, Marcos Lopez
المصدر: Cancer Biology & Therapy. 12:707-717
مصطلحات موضوعية: Cancer Research, Indoles, Mevalonic Acid, Breast Neoplasms, Mevalonic acid, Antioxidants, Fatty Acids, Monounsaturated, Superoxide dismutase, chemistry.chemical_compound, Drug Delivery Systems, Organophosphorus Compounds, Breast cancer, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Cytotoxic T cell, Fluvastatin, Cytotoxicity, Pharmacology, chemistry.chemical_classification, Reactive oxygen species, biology, Drug Synergism, medicine.disease, Mitochondria, Oncology, chemistry, Biochemistry, Cell culture, biology.protein, Cancer research, Molecular Medicine, Female, Nitrogen Oxides, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Reactive Oxygen Species, Research Paper, medicine.drug
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المؤلفون: Andrew D. Hauser, Carol L. Williams, Nathan J. Schuld, Adam J. Gastonguay, Ellen L. Lorimer, Jessica M. Wilson
المصدر: Cell cycle (Georgetown, Tex.). 13(6)
مصطلحات موضوعية: rho GTP-Binding Proteins, Lung Neoplasms, Cell, Breast Neoplasms, Mice, SCID, Biology, medicine.disease_cause, Mice, Cyclin D1, Pancreatic cancer, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Proliferating Cell Nuclear Antigen, Report, medicine, Animals, Guanine Nucleotide Exchange Factors, Humans, Protein Isoforms, Molecular Biology, Cell Proliferation, Cell growth, Cell Cycle, Cancer, Cell Biology, Cell cycle, medicine.disease, Cell biology, Pancreatic Neoplasms, medicine.anatomical_structure, Cancer research, Heterografts, Female, Guanine nucleotide exchange factor, Carcinogenesis, Developmental Biology
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المؤلفون: Nathan J. Schuld, Nathan C. Simon, Carol L. Williams, Jeffrey S. Vervacke, Mark D. Distefano, Ellen L. Lorimer, Andrew D. Hauser, Joseph T. Barbieri
مصطلحات موضوعية: G protein, Farnesyltransferase, Amino Acid Motifs, Molecular Sequence Data, GTPase, Biochemistry, Geranylgeranylation, GTP-binding protein regulators, Prenylation, Sequence Analysis, Protein, Membrane Biology, Guanine Nucleotide Exchange Factors, Humans, Amino Acid Sequence, Molecular Biology, Monomeric GTP-Binding Proteins, biology, Cell Biology, Cell biology, HEK293 Cells, Models, Chemical, biology.protein, Rap1, Guanine nucleotide exchange factor, Software
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المؤلفون: Carmen Bergom, Jian Huang, Ellen L. Lorimer, Carol L. Williams, Alexander C. Mackinnon, Xiuxu Chen, Andrew D. Hauser, Nathan J. Schuld
مصطلحات موضوعية: rho GTP-Binding Proteins, Cancer Research, RHOA, Transcription, Genetic, RNA Splicing, Transplantation, Heterologous, RhoC, Breast Neoplasms, Kaplan-Meier Estimate, Mice, SCID, Article, Mice, Breast cancer, Cell Line, Tumor, medicine, Animals, Guanine Nucleotide Exchange Factors, Humans, Protein Isoforms, RNA, Messenger, RNA, Small Interfering, skin and connective tissue diseases, Molecular Biology, Transcription factor, Cell Proliferation, biology, NF-kappa B, Cancer, medicine.disease, Prognosis, Transplantation, Protein Transport, Carcinoma, Intraductal, Noninfiltrating, Cell Transformation, Neoplastic, Oncology, rhoC GTP-Binding Protein, Cancer research, biology.protein, MCF-7 Cells, Female, RNA Interference, Guanine nucleotide exchange factor, rhoA GTP-Binding Protein, RhoC GTP-Binding Protein, Neoplasm Transplantation, Protein Binding, Signal Transduction
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المؤلفون: Andrew D. Hauser, Carol L. Williams, Nathan J. Schuld, Michael B. Dwinell, Patrick Gonyo, Ellen L. Lorimer, Balaraman Kalyanaraman, Donna McAllister, Elizabeth Ntantie, John A. Auchampach
المصدر: Cell Cycle
مصطلحات موضوعية: Adenosine, Biochemistry, localization, Rats, Sprague-Dawley, Cell membrane, Cell Movement, Tumor Microenvironment, Guanine Nucleotide Exchange Factors, Small GTPase, Neoplasm Metastasis, Receptor, Rap1, Microscopy, Confocal, Cell biology, ADORA2B, medicine.anatomical_structure, Rap1GDS1, SmgGDS, Signal transduction, K-Ras, Signal Transduction, medicine.drug, isoprenylation, Immunoblotting, Molecular Sequence Data, Editorials: Cell Cycle Features, adenosine A2B receptor, Biology, Receptor, Adenosine A2B, Models, Biological, Prenylation, trafficking, Cell Adhesion, medicine, Animals, Humans, Immunoprecipitation, metastasis, cancer, Amino Acid Sequence, Cell adhesion, Molecular Biology, polybasic region, RhoA, Cell Biology, Rats, HEK293 Cells, rap GTP-Binding Proteins
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المؤلفون: Carmen Bergom, Patrick Gonyo, Kathleen R. Noon, Irene Aguilera-Barrantes, Carol L. Williams, Ellen L. Lorimer, Alexis J. Lawton, Benjamin C. Jennings, Jeremy W. Prokop, Andrew D. Hauser, Carol A. Fierke, Amy Rymaszewski, Alexander C. Mackinnon, Anne Frei
المصدر: Journal of Biological Chemistry. 291:10948
مصطلحات موضوعية: 0301 basic medicine, RHOA, Breast Neoplasms, Plasma protein binding, GTPase, Biology, Guanosine triphosphate, Guanosine Diphosphate, Biochemistry, Protein Structure, Secondary, GTP Phosphohydrolases, Proto-Oncogene Proteins p21(ras), chemistry.chemical_compound, 03 medical and health sciences, Guanine Nucleotide Exchange Factors, Humans, Small GTPase, Amino Acid Sequence, Molecular Biology, Chemistry, Tumor Suppressor Proteins, Carcinoma, Ductal, Breast, NF-kappa B, Cell Biology, Cell biology, Molecular Docking Simulation, HEK293 Cells, 030104 developmental biology, Guanosine diphosphate, biology.protein, Cancer research, MCF-7 Cells, Additions and Corrections, Guanosine Triphosphate, Guanine nucleotide exchange factor, rhoA GTP-Binding Protein, Protein Binding, Signal Transduction
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المؤلفون: Nathan J. Schuld, Mark D. Distefano, Ellen L. Lorimer, Jeffrey S. Vervacke, Andrew D. Hauser, Carol L. Williams
المصدر: Molecular Cancer Research. 12:A53-A53
مصطلحات موضوعية: Cancer Research, biology, Farnesyltransferase, Cell, Wild type, GTPase, Cell cycle, medicine.anatomical_structure, Cyclin D1, Geranylgeranylation, Oncology, Prenylation, medicine, biology.protein, Cancer research, Molecular Biology
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المؤلفون: Patrick Gonyo, Andrew D. Hauser, Carmen Bergom, Carol L. Williams, Anne Frei, Ellen L. Lorimer, Kristen M. Barr
المصدر: Cancer Research. 74:4443-4443
مصطلحات موضوعية: Cancer Research, RHOA, Cell, HEK 293 cells, GTPase, Biology, Cell biology, medicine.anatomical_structure, Oncology, Cell culture, Gene expression, medicine, DIRAS3, biology.protein, Small GTPase
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المؤلفون: Carmen Bergom, R. Li, Alexander C. Mackinnon, Andrew D. Hauser, Ellen L. Lorimer, Carol L. Williams
المصدر: Journal of Clinical Oncology. 29:225-225
مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Gene knockdown, RHOA, Cell growth, RAC1, Biology, medicine.disease, Prostate cancer, Breast cancer, Internal medicine, medicine, biology.protein, Cancer research, Immunohistochemistry, splice, skin and connective tissue diseases