المؤلفون: Michael W. Grunst, Hwi Min Gil, Andres G. Grandea III, Brian J. Snow, Raiees Andrabi, Rebecca Nedellec, Iszac Burton, Natasha M. Clark, Sanath Kumar Janaka, Nida K. Keles, Ryan V. Moriarty, Andrea M. Weiler, Saverio Capuano III, Christine M. Fennessey, Thomas C. Friedrich, Shelby L. O’Connor, David H. O’Connor, Aimee T. Broman, Brandon F. Keele, Jeffrey D. Lifson, Lars Hangartner, Dennis R. Burton, David T. Evans

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Molecular Biology, Biotechnology, Evolutionary Biology, Immunology, Cancer, Mental Health, Infectious Diseases, Plant Biology, Virology, despite high concentrations, dependent cellular cytotoxicity, two additional groups, animals became infected, treated animals compared, div >< p, treated control animals, six rhesus macaques, potent adcc activity, increases pgt145 binding, 1 env trimer, treated animals, six macaques, separate groups, infected cells, 1 replication, potent antibody, control antibody

Relation: https://figshare.com/articles/figure/PGT145_does_not_exert_detectable_selective_pressure_on_Env_after_challenge_with_wild-type_SIV_sub_mac_sub_239_/25043035

الاتاحة: https://doi.org/10.1371/journal.ppat.1011819.s001
https://figshare.com/articles/figure/PGT145_does_not_exert_detectable_selective_pressure_on_Env_after_challenge_with_wild-type_SIV_sub_mac_sub_239_/25043035

المؤلفون: Michael W. Grunst, Hwi Min Gil, Andres G. Grandea III, Brian J. Snow, Raiees Andrabi, Rebecca Nedellec, Iszac Burton, Natasha M. Clark, Sanath Kumar Janaka, Nida K. Keles, Ryan V. Moriarty, Andrea M. Weiler, Saverio Capuano III, Christine M. Fennessey, Thomas C. Friedrich, Shelby L. O’Connor, David H. O’Connor, Aimee T. Broman, Brandon F. Keele, Jeffrey D. Lifson, Lars Hangartner, Dennis R. Burton, David T. Evans

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Molecular Biology, Biotechnology, Evolutionary Biology, Immunology, Cancer, Mental Health, Infectious Diseases, Plant Biology, Virology, despite high concentrations, dependent cellular cytotoxicity, two additional groups, animals became infected, treated animals compared, div >< p, treated control animals, six rhesus macaques, potent adcc activity, increases pgt145 binding, 1 env trimer, treated animals, six macaques, separate groups, infected cells, 1 replication, potent antibody, control antibody

Relation: https://figshare.com/articles/figure/Serum_concentrations_of_PGT145_decline_after_passive_administration_/25043367

الاتاحة: https://doi.org/10.1371/journal.ppat.1011819.s003
https://figshare.com/articles/figure/Serum_concentrations_of_PGT145_decline_after_passive_administration_/25043367

المؤلفون: Michael W. Grunst, Hwi Min Gil, Andres G. Grandea III, Brian J. Snow, Raiees Andrabi, Rebecca Nedellec, Iszac Burton, Natasha M. Clark, Sanath Kumar Janaka, Nida K. Keles, Ryan V. Moriarty, Andrea M. Weiler, Saverio Capuano III, Christine M. Fennessey, Thomas C. Friedrich, Shelby L. O’Connor, David H. O’Connor, Aimee T. Broman, Brandon F. Keele, Jeffrey D. Lifson, Lars Hangartner, Dennis R. Burton, David T. Evans

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Molecular Biology, Biotechnology, Evolutionary Biology, Immunology, Cancer, Mental Health, Infectious Diseases, Plant Biology, Virology, despite high concentrations, dependent cellular cytotoxicity, two additional groups, animals became infected, treated animals compared, div >< p, treated control animals, six rhesus macaques, potent adcc activity, increases pgt145 binding, 1 env trimer, treated animals, six macaques, separate groups, infected cells, 1 replication, potent antibody, control antibody

Relation: https://figshare.com/articles/figure/Resistance_of_the_SIVmac239_K180S_challenge_virus_to_neutralization_by_PGT145_/25043364

الاتاحة: https://doi.org/10.1371/journal.ppat.1011819.s002
https://figshare.com/articles/figure/Resistance_of_the_SIVmac239_K180S_challenge_virus_to_neutralization_by_PGT145_/25043364

المؤلفون: Michael W. Grunst, Hwi Min Gil, Andres G. Grandea III, Brian J. Snow, Raiees Andrabi, Rebecca Nedellec, Iszac Burton, Natasha M. Clark, Sanath Kumar Janaka, Nida K. Keles, Ryan V. Moriarty, Andrea M. Weiler, Saverio Capuano III, Christine M. Fennessey, Thomas C. Friedrich, Shelby L. O’Connor, David H. O’Connor, Aimee T. Broman, Brandon F. Keele, Jeffrey D. Lifson, Lars Hangartner, Dennis R. Burton, David T. Evans

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Molecular Biology, Biotechnology, Evolutionary Biology, Immunology, Cancer, Mental Health, Infectious Diseases, Plant Biology, Virology, despite high concentrations, dependent cellular cytotoxicity, two additional groups, animals became infected, treated animals compared, div >< p, treated control animals, six rhesus macaques, potent adcc activity, increases pgt145 binding, 1 env trimer, treated animals, six macaques, separate groups, infected cells, 1 replication, potent antibody, control antibody

Relation: https://figshare.com/articles/figure/Sensitivity_of_SIV_sub_mac_sub_239_and_SIV_sub_mac_sub_239_K180S_to_PGT145-mediated_ADCC_and_neutralization_/25043370

الاتاحة: https://doi.org/10.1371/journal.ppat.1011819.g001
https://figshare.com/articles/figure/Sensitivity_of_SIV_sub_mac_sub_239_and_SIV_sub_mac_sub_239_K180S_to_PGT145-mediated_ADCC_and_neutralization_/25043370

المؤلفون: Michael W. Grunst, Hwi Min Gil, Andres G. Grandea III, Brian J. Snow, Raiees Andrabi, Rebecca Nedellec, Iszac Burton, Natasha M. Clark, Sanath Kumar Janaka, Nida K. Keles, Ryan V. Moriarty, Andrea M. Weiler, Saverio Capuano III, Christine M. Fennessey, Thomas C. Friedrich, Shelby L. O’Connor, David H. O’Connor, Aimee T. Broman, Brandon F. Keele, Jeffrey D. Lifson, Lars Hangartner, Dennis R. Burton, David T. Evans

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Molecular Biology, Biotechnology, Evolutionary Biology, Immunology, Cancer, Mental Health, Infectious Diseases, Plant Biology, Virology, despite high concentrations, dependent cellular cytotoxicity, two additional groups, animals became infected, treated animals compared, div >< p, treated control animals, six rhesus macaques, potent adcc activity, increases pgt145 binding, 1 env trimer, treated animals, six macaques, separate groups, infected cells, 1 replication, potent antibody, control antibody

Relation: https://figshare.com/articles/figure/Structural_analysis_of_Env_substitutions_selected_in_SIV_sub_mac_sub_239_K180S_/25043382

الاتاحة: https://doi.org/10.1371/journal.ppat.1011819.g005
https://figshare.com/articles/figure/Structural_analysis_of_Env_substitutions_selected_in_SIV_sub_mac_sub_239_K180S_/25043382

المؤلفون: Michael W. Grunst, Hwi Min Gil, Andres G. Grandea III, Brian J. Snow, Raiees Andrabi, Rebecca Nedellec, Iszac Burton, Natasha M. Clark, Sanath Kumar Janaka, Nida K. Keles, Ryan V. Moriarty, Andrea M. Weiler, Saverio Capuano III, Christine M. Fennessey, Thomas C. Friedrich, Shelby L. O’Connor, David H. O’Connor, Aimee T. Broman, Brandon F. Keele, Jeffrey D. Lifson, Lars Hangartner, Dennis R. Burton, David T. Evans

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Molecular Biology, Biotechnology, Evolutionary Biology, Immunology, Cancer, Mental Health, Infectious Diseases, Plant Biology, Virology, despite high concentrations, dependent cellular cytotoxicity, two additional groups, animals became infected, treated animals compared, div >< p, treated control animals, six rhesus macaques, potent adcc activity, increases pgt145 binding, 1 env trimer, treated animals, six macaques, separate groups, infected cells, 1 replication, potent antibody, control antibody

Relation: https://figshare.com/articles/dataset/PGT145_concentration_ADCC_and_neutralizing_antibody_titers_on_the_day_of_challenge_/25043385

الاتاحة: https://doi.org/10.1371/journal.ppat.1011819.t001
https://figshare.com/articles/dataset/PGT145_concentration_ADCC_and_neutralizing_antibody_titers_on_the_day_of_challenge_/25043385

المؤلفون: Michael W. Grunst, Hwi Min Gil, Andres G. Grandea III, Brian J. Snow, Raiees Andrabi, Rebecca Nedellec, Iszac Burton, Natasha M. Clark, Sanath Kumar Janaka, Nida K. Keles, Ryan V. Moriarty, Andrea M. Weiler, Saverio Capuano III, Christine M. Fennessey, Thomas C. Friedrich, Shelby L. O’Connor, David H. O’Connor, Aimee T. Broman, Brandon F. Keele, Jeffrey D. Lifson, Lars Hangartner, Dennis R. Burton, David T. Evans

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Molecular Biology, Biotechnology, Evolutionary Biology, Immunology, Cancer, Mental Health, Infectious Diseases, Plant Biology, Virology, despite high concentrations, dependent cellular cytotoxicity, two additional groups, animals became infected, treated animals compared, div >< p, treated control animals, six rhesus macaques, potent adcc activity, increases pgt145 binding, 1 env trimer, treated animals, six macaques, separate groups, infected cells, 1 replication, potent antibody, control antibody

Relation: https://figshare.com/articles/figure/PGT145_treatment_selects_for_amino_acid_changes_in_Env_that_confer_resistance_to_ADCC_and_to_neutralization_/25043379

الاتاحة: https://doi.org/10.1371/journal.ppat.1011819.g004
https://figshare.com/articles/figure/PGT145_treatment_selects_for_amino_acid_changes_in_Env_that_confer_resistance_to_ADCC_and_to_neutralization_/25043379

المؤلفون: Michael W. Grunst, Hwi Min Gil, Andres G. Grandea III, Brian J. Snow, Raiees Andrabi, Rebecca Nedellec, Iszac Burton, Natasha M. Clark, Sanath Kumar Janaka, Nida K. Keles, Ryan V. Moriarty, Andrea M. Weiler, Saverio Capuano III, Christine M. Fennessey, Thomas C. Friedrich, Shelby L. O’Connor, David H. O’Connor, Aimee T. Broman, Brandon F. Keele, Jeffrey D. Lifson, Lars Hangartner, Dennis R. Burton, David T. Evans

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Molecular Biology, Biotechnology, Evolutionary Biology, Immunology, Cancer, Mental Health, Infectious Diseases, Plant Biology, Virology, despite high concentrations, dependent cellular cytotoxicity, two additional groups, animals became infected, treated animals compared, div >< p, treated control animals, six rhesus macaques, potent adcc activity, increases pgt145 binding, 1 env trimer, treated animals, six macaques, separate groups, infected cells, 1 replication, potent antibody, control antibody

Relation: https://figshare.com/articles/figure/PGT145_does_not_protect_against_wild-type_SIV_sub_mac_sub_239_challenge_/25043373

الاتاحة: https://doi.org/10.1371/journal.ppat.1011819.g002
https://figshare.com/articles/figure/PGT145_does_not_protect_against_wild-type_SIV_sub_mac_sub_239_challenge_/25043373

المؤلفون: Michael W. Grunst, Hwi Min Gil, Andres G. Grandea III, Brian J. Snow, Raiees Andrabi, Rebecca Nedellec, Iszac Burton, Natasha M. Clark, Sanath Kumar Janaka, Nida K. Keles, Ryan V. Moriarty, Andrea M. Weiler, Saverio Capuano III, Christine M. Fennessey, Thomas C. Friedrich, Shelby L. O’Connor, David H. O’Connor, Aimee T. Broman, Brandon F. Keele, Jeffrey D. Lifson, Lars Hangartner, Dennis R. Burton, David T. Evans

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Molecular Biology, Biotechnology, Evolutionary Biology, Immunology, Cancer, Mental Health, Infectious Diseases, Plant Biology, Virology, despite high concentrations, dependent cellular cytotoxicity, two additional groups, animals became infected, treated animals compared, div >< p, treated control animals, six rhesus macaques, potent adcc activity, increases pgt145 binding, 1 env trimer, treated animals, six macaques, separate groups, infected cells, 1 replication, potent antibody, control antibody

Relation: https://figshare.com/articles/figure/PGT145_affords_partial_protection_against_SIV_sub_mac_sub_239_K180S_challenge_/25043376

الاتاحة: https://doi.org/10.1371/journal.ppat.1011819.g003
https://figshare.com/articles/figure/PGT145_affords_partial_protection_against_SIV_sub_mac_sub_239_K180S_challenge_/25043376

المؤلفون: Michael W. Grunst, Hwi Min Gil, Andres G. Grandea III, Brian J. Snow, Raiees Andrabi, Rebecca Nedellec, Iszac Burton, Natasha M. Clark, Sanath Kumar Janaka, Nida K. Keles, Ryan V. Moriarty, Andrea M. Weiler, Saverio Capuano III, Christine M. Fennessey, Thomas C. Friedrich, Shelby L. O’Connor, David H. O’Connor, Aimee T. Broman, Brandon F. Keele, Jeffrey D. Lifson, Lars Hangartner, Dennis R. Burton, David T. Evans

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Molecular Biology, Biotechnology, Evolutionary Biology, Immunology, Cancer, Mental Health, Infectious Diseases, Plant Biology, Virology, despite high concentrations, dependent cellular cytotoxicity, two additional groups, animals became infected, treated animals compared, div >< p, treated control animals, six rhesus macaques, potent adcc activity, increases pgt145 binding, 1 env trimer, treated animals, six macaques, separate groups, infected cells, 1 replication, potent antibody, control antibody

Relation: https://figshare.com/articles/dataset/Rhesus_macaques_/25043388

الاتاحة: https://doi.org/10.1371/journal.ppat.1011819.t002
https://figshare.com/articles/dataset/Rhesus_macaques_/25043388