المؤلفون: Enja Schneider, Riekje Winzer, Anne Rissiek, Isabell Ricklefs, Catherine Meyer-Schwesinger, Franz L. Ricklefs, Andreas Bauche, Jochen Behrends, Rudolph Reimer, Santra Brenna, Hauke Wasielewski, Melchior Lauten, Björn Rissiek, Berta Puig, Filippo Cortesi, Tim Magnus, Ralf Fliegert, Christa E. Müller, Nicola Gagliani, Eva Tolosa

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/423c6b103e9d4f51bf3e93a6880c1a59

المؤلفون: Winnie Maria Riekehr, Simon Sander, Jelena Pick, Henning Tidow, Andreas Bauche, Andreas H. Guse, Ralf Fliegert

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 6; Pages: 3163

مصطلحات موضوعية: transient receptor potential channel, cyclic adenosine 5′-diphosphate ribose, second messenger, calcium signalling

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Biochemistry; https://dx.doi.org/10.3390/ijms23063163

الاتاحة: https://doi.org/10.3390/ijms23063163

المؤلفون: Natalie Baum, Ralf Fliegert, Andreas Bauche, Julia Hambach, Stephan Menzel, Friedrich Haag, Peter Bannas, Friedrich Koch-Nolte

المصدر: Cancers; Volume 13; Issue 1; Pages: 76

مصطلحات موضوعية: multiple myeloma, CD38, ecto-enzyme, NAD + hydrolase, antibodies, heavy-chain antibodies, nanobodies

وصف الملف: application/pdf

Relation: Tumor Microenvironment; https://dx.doi.org/10.3390/cancers13010076

الاتاحة: https://doi.org/10.3390/cancers13010076

المؤلفون: Simon Sander, Ralf Fliegert, Trevor J. Rutherford, Henning Tidow, Ellen Gattkowski, Andreas Bauche, Franziska Möckl

المصدر: The FEBS journal 288(23), 6769-6782 (2021). doi:10.1111/febs.16097

مصطلحات موضوعية: Conformational change, Magnetic Resonance Spectroscopy, Protein Conformation, Ligands, Binding, Competitive, Biochemistry, Nudix hydrolase, Substrate Specificity, X-Ray Diffraction, Scattering, Small Angle, Humans, TRPM2, ddc:610, Enzyme kinetics, Pyrophosphatases, Binding site, Molecular Biology, Adenosine Diphosphate Ribose, Binding Sites, Chemistry, Cell Biology, Protein superfamily, Ligand (biochemistry), Molecular Docking Simulation, Kinetics, Förster resonance energy transfer, Mutation, Biophysics, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193e9de228d91112d6d0b07cc82257e7
https://doi.org/10.1111/febs.16097

المؤلفون: Parimah, Ahmadi, Ming, Yan, Andreas, Bauche, Ralf, Smeets, Christa E, Müller, Friedrich, Koch-Nolte, Friedrich, Haag, Ralf, Fliegert, Lan, Kluwe, Julian, Schulze Zur Wiesch, Philip, Hartjen

المصدر: Cellular immunology. 380

مصطلحات موضوعية: Adenosine, Adenosine Triphosphate, Humans, CD8-Positive T-Lymphocytes, 5'-Nucleotidase, Dental Pulp, Cell Proliferation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::a002ea2f34d4c613d0a051bc44c1b0c1
https://pubmed.ncbi.nlm.nih.gov/36084401

المؤلفون: Ralf Fliegert, Peter Bannas, Andreas Bauche, Stephan Menzel, Natalie Baum, Friedrich Koch-Nolte, Julia Hambach, Friedrich Haag

المصدر: Cancers, Vol 13, Iss 76, p 76 (2021)
Cancers
Volume 13
Issue 1

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.drug_class, Cell, CD38, Monoclonal antibody, lcsh:RC254-282, 03 medical and health sciences, 0302 clinical medicine, heavy-chain antibodies, hemic and lymphatic diseases, Hydrolase, medicine, antibodies, Cytotoxicity, ecto-enzyme, biology, Chemistry, Daratumumab, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Molecular biology, nanobodies, multiple myeloma, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, biology.protein, NAD+ kinase, Antibody, NAD+ hydrolase

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::021f84c30da5920dff0c865fe8a8c300
https://www.mdpi.com/2072-6694/13/1/76

المؤلفون: Feng, Gu, Aileen, Krüger, Hannes G, Roggenkamp, Rick, Alpers, Dmitri, Lodygin, Vincent, Jaquet, Franziska, Möckl, Lola C, Hernandez C, Kai, Winterberg, Andreas, Bauche, Anette, Rosche, Helmut, Grasberger, John Y, Kao, Daniel, Schetelig, René, Werner, Katrin, Schröder, Michael, Carty, Andrew G, Bowie, Samuel, Huber, Chris, Meier, Hans-Willi, Mittrücker, Joerg, Heeren, Karl-Heinz, Krause, Alexander, Flügel, Björn-Philipp, Diercks, Andreas H, Guse

المصدر: Science signaling. 14(709)

مصطلحات موضوعية: Mice, Knockout, Jurkat Cells, HEK293 Cells, T-Lymphocytes, Animals, Humans, NADPH Oxidases, Calcium Signaling, Lymphocyte Activation, Dual Oxidases, NADP

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::f6ffb46d6bcdbb7d6dd52bfdf74fb13a
https://pubmed.ncbi.nlm.nih.gov/34784249

المؤلفون: Ralf Fliegert, Anette Rosche, Valerie Wolters, Frederike Kulow, Angelika Harneit, Andreas H. Guse, Andreas Bauche

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1866:1189-1196

مصطلحات موضوعية: Mutant, Nicotinamide adenine dinucleotide, Cyclase, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Humans, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Binding Sites, Membrane Glycoproteins, Chemistry, Tryptophan, Cell Biology, NAD, ADP-ribosyl Cyclase 1, NAD binding, Dissociation constant, Kinetics, HEK293 Cells, Enzyme, Biophysics, NAD+ kinase, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81fc28a2395de16c4dce508d84139d4d
https://doi.org/10.1016/j.bbamcr.2018.11.011

المؤلفون: Franziska Möckl, Frederike Kulow, Ralf Fliegert, Andreas Bauche, Trevor J. Rutherford, Maria Garcia Alai, Henning Tidow, Anke Johnsen, Ellen Gattkowski

المصدر: Biochimica et Biophysica Acta. Molecular Cell Research

مصطلحات موضوعية: 0301 basic medicine, Hot Temperature, Temperature sensitivity, Amino Acid Motifs, CAM binding, TRPM Cation Channels, Article, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, Humans, Thermotaxis, TRPM2, Molecular Biology, 2′-deoxy-ADPR, Protein Stability, Chemistry, Temperature sensor, Calcium channel, Cell Biology, Cell function, HEK293 Cells, 030104 developmental biology, Biophysics, Calmodulin-binding, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::861fb6008715f62142b2f133ab95c850
https://doi.org/10.1016/j.bbamcr.2018.12.010

المؤلفون: null Ellen Gattkowski, null Trevor J. Rutherford, null Franziska Möckl, null Andreas Bauche, null Simon Sander, null Ralf Fliegert, null Henning Tidow

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1e631331cce8e85eaf19a870c0db6126
https://doi.org/10.1111/febs.16097/v2/response1

المؤلفون: Francesca Odoardi, Eva Tolosa, Anette Rosche, Wolfgang Dohle, Leon Hosang, Andreas H. Guse, Barry V. L. Potter, Sabine Windhorst, Riekje Winzer, Anke Löhndorf, Andreas Bauche, Alexander Flügel, Stephen Marry, Björn-Philipp Diercks, Sissy-Alina Waschkowski

مصطلحات موضوعية: 0303 health sciences, Chemistry, Cell growth, T cell, Endoplasmic reticulum, Chemical biology, NFAT, Cell Biology, Cell biology, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Second messenger system, medicine, 2-Methoxyestradiol, Molecular Biology, Ion channel, 030304 developmental biology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb2c8fa726a5b9cc25114b1dc923648
https://ora.ox.ac.uk/objects/uuid:0625f9f7-6c8f-43ac-89bf-0f8646db7cac

المؤلفون: Hannes G, Roggenkamp, Imrankhan, Khansahib, Lola C, Hernandez C, Yunpeng, Zhang, Dmitri, Lodygin, Aileen, Krüger, Feng, Gu, Franziska, Möckl, Anke, Löhndorf, Valerie, Wolters, Daniel, Woike, Anette, Rosche, Andreas, Bauche, Daniel, Schetelig, René, Werner, Hartmut, Schlüter, Antonio V, Failla, Chris, Meier, Ralf, Fliegert, Timothy F, Walseth, Alexander, Flügel, Björn-Philipp, Diercks, Andreas H, Guse

المصدر: Science signaling. 14(675)

مصطلحات موضوعية: CD3 Complex, T-Lymphocytes, Receptors, Antigen, T-Cell, Ryanodine Receptor Calcium Release Channel, Endoplasmic Reticulum, Lymphocyte Activation, Rats, Jurkat Cells, Membrane Microdomains, Animals, Humans, Calcium, Calcium Signaling, Microtubule-Associated Proteins, NADP, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::dd7a3b5421e3b72e6a971c51dc8765a4
https://pubmed.ncbi.nlm.nih.gov/33758059

المؤلفون: Aileen Krüger, Björn-Philipp Diercks, Franziska Möckl, Daniel Woike, Hannes G. Roggenkamp, Timothy F. Walseth, Anke Löhndorf, C C Lola Hernandez, René Werner, Yunpeng Zhang, Antonio Virgilio Failla, Chris Meier, Andreas H. Guse, Ralf Fliegert, Alexander Flügel, Andreas Bauche, Valerie Wolters, Imrankhan Khansahib, Dmitri Lodygin, Feng Gu, Hartmut Schlüter, Anette Rosche, Daniel Schetelig

المصدر: Science Signaling. 14

مصطلحات موضوعية: 0303 health sciences, Photoaffinity labeling, Chemistry, Ryanodine receptor, Endoplasmic reticulum, T cell, 030302 biochemistry & molecular biology, T-cell receptor, Lipid microdomain, Colocalization, Cell Biology, Biochemistry, Jurkat cells, Cell biology, 03 medical and health sciences, medicine.anatomical_structure, medicine, Molecular Biology, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bb6e37db9630c34fca772a97c3122f3e
https://doi.org/10.1126/scisignal.abd5647

المؤلفون: Chris Meier, John Y. Kao, Michael Carty, Aileen Krüger, Samuel Huber, Vincent Jaquet, René Werner, Andrew G. Bowie, Feng Gu, Dmitri Lodygin, Katrin Schröder, Björn-Philipp Diercks, Franziska Möckl, Alexander Flügel, Joerg Heeren, Helmut Grasberger, C C Lola Hernandez, Rick Alpers, Hannes G. Roggenkamp, Hans-Willi Mittrücker, Andreas Bauche, Daniel Schetelig, Anette Rosche, Karl-Heinz Krause, Andreas H. Guse, Kai Winterberg

المصدر: Science signaling, Vol. 14, No 709 (2021) P. eabe3800

مصطلحات موضوعية: T cell, ddc:616.07, Lymphocyte Activation, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Jurkat Cells, 0302 clinical medicine, medicine, Animals, Humans, Calcium Signaling, Dual Oxidases / genetics, Molecular Biology, 030304 developmental biology, NADP / biosynthesis, Mice, Knockout, 0303 health sciences, Nicotinic acid adenine dinucleotide phosphate, Chemistry, T-Lymphocytes / enzymology, NADP / analogs & derivatives, Cell Biology, 3. Good health, medicine.anatomical_structure, HEK293 Cells, cardiovascular system, NADPH Oxidases / genetics, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a23387c8a6964d84752430a7ab79ff97
https://archive-ouverte.unige.ch/unige:159330

المؤلفون: Andreas Bauche, Melchior Lauten, Filippo Cortesi, Björn Rissiek, Berta Puig, Franz Ricklefs, Christa E. Müller, Enja Schneider, Ralf Fliegert, Isabell Ricklefs, Tim Magnus, Riekje Winzer, Nicola Gagliani, Jochen Behrends, Catherine Meyer-Schwesinger, Rudolph Reimer, Hauke Wasielewski, Anne Rissiek, Eva Tolosa, Santra Brenna

المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Adenosine, T cell, Science, T-Lymphocytes, T cells, General Physics and Astronomy, Translational immunology, Inflammation, Autoimmunity, CD8-Positive T-Lymphocytes, GPI-Linked Proteins, Lymphocyte Activation, T-Lymphocytes, Regulatory, General Biochemistry, Genetics and Molecular Biology, Article, Extracellular Vesicles, Mice, Immune system, Adenosine Triphosphate, Antigen, medicine, Extracellular, Cytotoxic T cell, Animals, Humans, 5'-Nucleotidase, Cell Proliferation, Immunosuppression Therapy, Multidisciplinary, Chemistry, Peripheral tolerance, General Chemistry, biochemical phenomena, metabolism, and nutrition, Cell biology, medicine.anatomical_structure, bacteria, medicine.symptom, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ccc99c9773416ffc995941d614accd
https://pubmed.ncbi.nlm.nih.gov/34625545

المؤلفون: Anke, Löhndorf, Leon, Hosang, Wolfgang, Dohle, Francesca, Odoardi, Sissy-Alina, Waschkowski, Anette, Rosche, Andreas, Bauche, Riekje, Winzer, Eva, Tolosa, Sabine, Windhorst, Stephen, Marry, Alexander, Flügel, Barry V L, Potter, Björn-Philipp, Diercks, Andreas H, Guse

المصدر: Biochimica et Biophysica Acta. Molecular Cell Research

مصطلحات موضوعية: TG, thapsigargin, MBP, myelin basic protein, NCS, newborn calf serum, T-Lymphocytes, ROI, region of interest, cADPR, cyclic ADP-ribose, E2, estradiol, Im, ionomycin, Lymphocyte Activation, Jurkat Cells, KV, voltage-gated potassium channel, PCR, polymerase chain reaction, Estrenes, EAE, experimental autoimmune encephalomyelitis, GFP, green fluorescent protein, TMBP, myelin basic protein-reactive CD4+ rat T cells, TCR, T cell receptor, T cell activation, G-GECO, green fluorescent genetically encoded Ca2+ indicator for optical imaging, PLL, poly-l-lysine, Protein Transport, cmp, compound, NFAT, nuclear factor of activated T cells, SERCA, sarco/endoplasmic reticulum Ca2+ ATPase, SOCE, store-operated Ca2+ entry, Kd, dissociation constant, ATP, adenosine triphosphate, IP3, d-myo-inositol 1,4,5-trisphosphate, CD, cluster of differentiation, IgG, immunoglobulin G, CNS, central nervous system, Article, Cell Line, HPLC, high-pressure liquid chromatography, MS, multiple sclerosis, ER, endoplasmic reticulum, AM, acetoxymethyl ester, F, fluorescence, Animals, Humans, Calcium Signaling, NMR, nuclear magnetic resonance, Ca2+ signaling, Cell Nucleus, [Ca2+]i, free cytosolic calcium concentration, NFATC Transcription Factors, TRPA, transient receptor potential ion channel type A, ORAI inhibitor, TRPV, transient receptor potential ion channel type V, NAADP, nicotinic acid adenine dinucleotide phosphate, Th1/2, T helper cells type 1/2, 2ME2, 2-methoxyestradiol, ADP, adenosine diphosphate, 2-Methoxyestradiol, Rats, IL, interleukin, Gene Expression Regulation, APC, antigen-presenting cell, Store-operated Ca2+ entry, Calcium, BSA, bovine serum albumin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::650c8916b8b8725f26a562fc2fff0d16
https://pubmed.ncbi.nlm.nih.gov/33581218

المؤلفون: Christelle Moreau, Angelika Harneit, Adriana-Michelle Wolf Pérez, Marianne Flato, Annette Rosche, Feng Gu, Joanna M. Watt, Ralf Fliegert, Tanja Kirchberger, Andreas H. Guse, Mareike Janus, Riekje Winzer, Monika D. Rozewitz, Valerie Wolters, Andreas Bauche, Barry V. L. Potter

المصدر: Fliegert, R, Bauche, A, Wolf Pérez, A-M, Watt, J M, Rozewitz, M D, Winzer, R, Janus, M, Gu, F, Rosche, A, Harneit, A, Flato, M, Moreau, C, Kirchberger, T, Wolters, V, Potter, B V L & Guse, A H 2017, ' 2ʹ-Deoxyadenosine 5ʹ-diphosphoribose is an endogenous TRPM2 superagonist ', Nature Chemical Biology, vol. 13, pp. 1036-1044 . https://doi.org/10.1038/nchembio.2415

مصطلحات موضوعية: 0301 basic medicine, Agonist, medicine.drug_class, Endogeny, Nicotinamide adenine dinucleotide, Jurkat cells, Article, 03 medical and health sciences, chemistry.chemical_compound, Jurkat Cells, medicine, Humans, TRPM2, Molecular Biology, Chromatography, High Pressure Liquid, Nicotinamide mononucleotide, Adenosine Diphosphate Ribose, Molecular Structure, Chemistry, Cell Biology, Hydrogen Peroxide, Adenosine, ADP-ribosyl Cyclase 1, 030104 developmental biology, Clusterin, Biochemistry, NAD+ kinase, medicine.drug, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98326694e9d3f2fec0bd754b24256d0c
https://europepmc.org/articles/PMC5563452/

المؤلفون: Tim Westphal, Andreas H. Guse, Andreas Bauche, Ralf Fliegert, Frederike Schmid

المصدر: Journal of Biological Chemistry. 287:32525-32534

مصطلحات موضوعية: Phosphatase, Biology, Biochemistry, Jurkat cells, Gene Expression Regulation, Enzymologic, HeLa, Jurkat Cells, chemistry.chemical_compound, Humans, Molecular Biology, chemistry.chemical_classification, Membrane Glycoproteins, Nicotinic acid adenine dinucleotide phosphate, Cell Membrane, HEK 293 cells, Cell Biology, Hydrogen-Ion Concentration, Alkaline Phosphatase, biology.organism_classification, ADP-ribosyl Cyclase 1, Isoenzymes, HEK293 Cells, Enzyme, chemistry, Second messenger system, Alkaline phosphatase, NADP, Signal Transduction, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb25052ee3f9aa5dc02ef192337cd56
https://doi.org/10.1074/jbc.m112.362715

المؤلفون: Andreas Bauche, Juliane Hannemann, Simon A. Joosse, Klaus Pantel, Antje Andreas, Volkmar Müller, Julia Spötter

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research. 18(4)

مصطلحات موضوعية: Oncology, CA15-3, Cancer Research, medicine.medical_specialty, Gene Expression, Breast Neoplasms, Biology, Breast cancer, Circulating tumor cell, Internal medicine, Cell Line, Tumor, Keratin, medicine, Humans, Lymph node, chemistry.chemical_classification, integumentary system, Gene Expression Profiling, Keratin-16, Cancer, medicine.disease, Neoplastic Cells, Circulating, Metastatic breast cancer, Survival Analysis, medicine.anatomical_structure, chemistry, Lymphatic Metastasis, biology.protein, Disease Progression, Keratins, Female, Antibody

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fdb429bd728b2edc7e973b48f36e1f
https://pubmed.ncbi.nlm.nih.gov/22228641

المؤلفون: Antonina Kruppa, Joachim Kruppa, Pia Schedewig, Andreas Bauche, Mark Perić

المصدر: European journal of cell biology. 87(1)

مصطلحات موضوعية: Ribosomal Proteins, alpha Karyopherins, Histology, Nucleolus, Recombinant Fusion Proteins, Active Transport, Cell Nucleus, Pathology and Forensic Medicine, Evolution, Molecular, Bacterial Proteins, Ribosomal protein, Chlorocebus aethiops, Animals, Amino Acid Sequence, Karyopherin, chemistry.chemical_classification, Nucleoplasm, biology, Thermus thermophilus, Cell Biology, General Medicine, Ribosomal RNA, biology.organism_classification, beta-Galactosidase, Biochemistry, chemistry, RNA, Ribosomal, COS Cells, Nuclear transport, Nuclear localization sequence, Cell Nucleolus

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd5852405c099b88d46cb9751c8814d
https://pubmed.ncbi.nlm.nih.gov/17881085