المؤلفون: Ellen Weisberg, Basudev Chowdhury, Chengcheng Meng, Abigail E. Case, Wei Ni, Swati Garg, Martin Sattler, Abdel Kareem Azab, Jennifer Sun, Barbara Muz, Dana Sanchez, Anthia Toure, Richard M. Stone, Ilene Galinsky, Eric Winer, Scott Gleim, Sofia Gkountela, Alexia Kedves, Edmund Harrington, Tinya Abrams, Thomas Zoller, Andrea Vaupel, Paul Manley, Michael Faller, BoYee Chung, Xin Chen, Philipp Busenhart, Christine Stephan, Keith Calkins, Debora Bonenfant, Claudio R. Thoma, William Forrester, James D. Griffin

المصدر: Blood Cancer Journal, Vol 12, Iss 7, Pp 1-10 (2022)

مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2044-5385

URL الوصول: https://doaj.org/article/3c275c0fed054a4ca5adaa6cd08da2ce

المؤلفون: Edwige Lorthiois, Marc Gerspacher, Kim S. Beyer, Andrea Vaupel, Catherine Leblanc, Rowan Stringer, Andreas Weiss, Rainer Wilcken, Daniel A. Guthy, Andreas Lingel, Claudio Bomio-Confaglia, Rainer Machauer, Pascal Rigollier, Johannes Ottl, Dorothee Arz, Pascal Bernet, Gaëlle Desjonqueres, Solene Dussauge, Malika Kazic-Legueux, Marie-Anne Lozac’h, Christophe Mura, Mickaël Sorge, Milen Todorov, Nicolas Warin, Florence Zink, Hans Voshol, Frederic J. Zecri, Richard C. Sedrani, Nils Ostermann, Saskia M. Brachmann, Simona Cotesta

المصدر: Journal of Medicinal Chemistry. 65:16173-16203

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ad7ccf3634960d3fbc0cb2fa59a10551
https://doi.org/10.1021/acs.jmedchem.2c01438

المؤلفون: Andreas Weiss, Edwige Lorthiois, Louise Barys, Kim S. Beyer, Claudio Bomio-Confaglia, Heather Burks, Xueying Chen, Xiaoming Cui, Ruben de Kanter, Lekshmi Dharmarajan, Carmine Fedele, Marc Gerspacher, Daniel Alexander Guthy, Victoria Head, Ashley Jaeger, Eloísa Jiménez Núñez, Jeffrey D. Kearns, Catherine Leblanc, Sauveur-Michel Maira, Jason Murphy, Helen Oakman, Nils Ostermann, Johannes Ottl, Pascal Rigollier, Danielle Roman, Christian Schnell, Richard Sedrani, Toshio Shimizu, Rowan Stringer, Andrea Vaupel, Hans Voshol, Peter Wessels, Toni Widmer, Rainer Wilcken, Kun Xu, Frederic Zecri, Anna F. Farago, Simona Cotesta, Saskia M. Brachmann

المصدر: Cancer Discovery. 12:1500-1517

مصطلحات موضوعية: Proto-Oncogene Proteins p21(ras), Indazoles, Oncology, Neoplasms, Mutation, Humans, Enzyme Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2edd83624df412b8b1d836bfe665fa6
https://doi.org/10.1158/2159-8290.cd-22-0158

المؤلفون: Saskia M. Brachmann, Simona Cotesta, Anna F. Farago, Frederic Zecri, Kun Xu, Rainer Wilcken, Toni Widmer, Peter Wessels, Hans Voshol, Andrea Vaupel, Rowan Stringer, Toshio Shimizu, Richard Sedrani, Christian Schnell, Danielle Roman, Pascal Rigollier, Johannes Ottl, Nils Ostermann, Helen Oakman, Jason Murphy, Sauveur-Michel Maira, Catherine Leblanc, Jeffrey D. Kearns, Eloísa Jiménez Núñez, Ashley Jaeger, Victoria Head, Daniel Alexander Guthy, Marc Gerspacher, Carmine Fedele, Lekshmi Dharmarajan, Ruben de Kanter, Xiaoming Cui, Xueying Chen, Heather Burks, Claudio Bomio-Confaglia, Kim S. Beyer, Louise Barys, Edwige Lorthiois, Andreas Weiss

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d58af020ff3289026b12e3df1b9a0f4
https://doi.org/10.1158/2159-8290.22541471.v1

المؤلفون: Saskia M. Brachmann, Simona Cotesta, Anna F. Farago, Frederic Zecri, Kun Xu, Rainer Wilcken, Toni Widmer, Peter Wessels, Hans Voshol, Andrea Vaupel, Rowan Stringer, Toshio Shimizu, Richard Sedrani, Christian Schnell, Danielle Roman, Pascal Rigollier, Johannes Ottl, Nils Ostermann, Helen Oakman, Jason Murphy, Sauveur-Michel Maira, Catherine Leblanc, Jeffrey D. Kearns, Eloísa Jiménez Núñez, Ashley Jaeger, Victoria Head, Daniel Alexander Guthy, Marc Gerspacher, Carmine Fedele, Lekshmi Dharmarajan, Ruben de Kanter, Xiaoming Cui, Xueying Chen, Heather Burks, Claudio Bomio-Confaglia, Kim S. Beyer, Louise Barys, Edwige Lorthiois, Andreas Weiss

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090908cffff39039ae33828ed26022f4
https://doi.org/10.1158/2159-8290.c.6549647

المؤلفون: Andreas Weiss, Hans Voshol, Diana Graus Porta, Carmine Fedele, Dario Sterker, Ruben De Kanter, Rowan Stringer, Toni Widmer, Alice Loo, Daniel A. Guthy, Kim S. Beyer, Nils Ostermann, Catherine LeBlanc, Marc Gerspacher, Andrea Vaupel, Richard Sedrani, Frederic Zecri, Saveur-Michel Maria, Francesco Hofmann, Peter Hammerman, Jeff Engelman, Edwige Lorthiois, Simona Cotesta, Saskia M. Brachmann

المصدر: Cancer Research. 82:4026-4026

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::214f14f8dca262dae57cbef9b3bf8657
https://doi.org/10.1158/1538-7445.am2022-4026

المؤلفون: Saskia M. Brachmann, Andreas Weiss, Daniel A. Guthy, Kim Beyer, Johannes Voshol, Michel Maira, Anirudh Prahallad, Diana Graus Porta, Christian Schnell, Nils Ostermann, Andrea Vaupel, Marc Gerspacher, Catherine Leblanc, Dirk Erdmann, Dario Sterker, Grainne Kerr, Giovannoni Jerome, Victoria Head, Rowan Stringer, Ruben De Kanter, Kearns Jeff, Danielle Roman, Toni Widmer, Peter Wessels, Eloisa Jimenez Nunez, Richard Sedrani, Frederic Zecri, Francesco Hofmann, Jeff Engleman, Edwige Lorthiois, Simona Cotesta

المصدر: Molecular Cancer Therapeutics. 20:P124-P124

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ad4b8e929a5d91731e7278c2de32193c
https://doi.org/10.1158/1535-7163.targ-21-p124

المؤلفون: Felix Gugerli, Roxane Muller, Andrea Vaupel, Janine Bolliger, Sabine Brodbeck, Hirzi Luqman

المصدر: Conservation Genetics. 19:673-685

مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, biology, Ecology, Biodiversity, biology.organism_classification, 010603 evolutionary biology, 01 natural sciences, Gene flow, 03 medical and health sciences, 030104 developmental biology, Genetic drift, Habitat, Effective population size, Genetic structure, Genetics, Biological dispersal, Ichthyosaura alpestris, Ecology, Evolution, Behavior and Systematics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5487af21a4a8a0bf34e56eece94ac8e9
https://doi.org/10.1007/s10592-018-1046-y

المؤلفون: Klaus Weigand, Andrea Vaupel, Roland Feifel, Berndt Oberhauser, Janet Dawson King, Mark Nash, Pius Loetscher, Amanda Littlewood-Evans, David Orain, Wolfgang Miltz, Juraj Velcicky

المصدر: Journal of Medicinal Chemistry. 60:3672-3683

مصطلحات موضوعية: Nociception, 0301 basic medicine, Angiogenesis, hERG, Administration, Oral, Neovascularization, Physiologic, Inflammation, Pharmacology, 01 natural sciences, Receptors, G-Protein-Coupled, Rats, Sprague-Dawley, Neovascularization, 03 medical and health sciences, Drug Discovery, medicine, Animals, Humans, Receptors, Histamine H3, Receptor, biology, 010405 organic chemistry, Chemistry, Antagonist, Rats, 0104 chemical sciences, HEK293 Cells, 030104 developmental biology, Drug Design, Hyperalgesia, biology.protein, Molecular Medicine, Female, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d140d7ef0960f3398069f19f6c5bc89f
https://doi.org/10.1021/acs.jmedchem.6b01703

المؤلفون: Gabi Schutzius, Michael Faller, Aimee Reynolds, Ralph Tiedt, Julia Klopp, Florian Fuchs, Laure C. Bouchez, Federico Tortelli, Nelly Leroy, Jonathan J. Turner, Guglielmo Roma, Simona Cotesta, Armin Beyerbach, Peter Drueckes, Shola M Richards, Debora Bonenfant, Heinrich Rueeger, Heinz Ruffner, Jutta Blank, Rémi Terranova, Peter Tarsa, Frederic Grandjean, Florian Nigsch, Sebastian Bergling, Natalie Dales, Alexandra Aebi, Paul W. Manley, Markus Schirle, Christian Kolter, Tewis Bouwmeester, Rene Hemmig, Sukhdeep Sahambi, Lori L. Jennings, Walter Carbone, Felix Lohmann, Alfred Zimmerlin, Jun Li, Susan Kirkland, Steffen Renner, Mathias Frederiksen, Vickie Driver, Amy Berwick, Florence Zink, Jason R. Thomas, Andrea Vaupel, Chris Dimitri, Vito Guagnano, Viktoria Gruber, Malvina Louis, Caroline Gubser Keller, Adrian Salathe

المصدر: Nature chemical biology. 17(3)

مصطلحات موضوعية: Keratinocytes, Male, Protein family, Transcription, Genetic, Phenotypic screening, Primary Cell Culture, Cell Cycle Proteins, Wounds, Nonpenetrating, Small Molecule Libraries, 03 medical and health sciences, Mice, Structure-Activity Relationship, Re-Epithelialization, In vivo, Skin Ulcer, medicine, Fluorescence Resonance Energy Transfer, Animals, Humans, Protein Isoforms, Protein Precursors, Molecular Biology, 030304 developmental biology, 0303 health sciences, integumentary system, Epidermis (botany), business.industry, 030302 biochemistry & molecular biology, Cell Biology, In vitro, Bromodomain, High-Throughput Screening Assays, Mice, Inbred C57BL, Disease Models, Animal, medicine.anatomical_structure, Gene Expression Regulation, Cancer research, Epidermis, Keratinocyte, business, Ex vivo, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a8580afdc9f2d099758e215f9da05e
https://pubmed.ncbi.nlm.nih.gov/33462495

المؤلفون: François Gessier, Robert Mah, Philipp Holzer, Therese-Marie Stachyra, Andrea Vaupel, Vito Guagnano, Emmanuelle Wirth, Patrick Chène, Pascal Furet, Joseph Schoepfer, Aude Izaac, Bahaa Salem, Stefan Stutz, Joerg Kallen, Keiichi Masuya, Achim Schlapbach, Suzanne Chau

المصدر: ChemMedChem. 14(14)

مصطلحات موضوعية: MDMX, Chemical compound, Cell Cycle Proteins, Computational biology, Crystallography, X-Ray, 01 natural sciences, Biochemistry, Protein–protein interaction, chemistry.chemical_compound, Heterocyclic Compounds, Proto-Oncogene Proteins, Drug Discovery, Humans, General Pharmacology, Toxicology and Pharmaceutics, Therapeutic strategy, Pharmacology, chemistry.chemical_classification, DNA ligase, Binding Sites, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Proto-Oncogene Proteins c-mdm2, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Flip, biology.protein, Molecular Medicine, Mdm2, Function (biology), Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f06228760b95695741263802f16121
https://pubmed.ncbi.nlm.nih.gov/31066983

المؤلفون: Kim S. Beyer, Christian Ragot, Andrea Vaupel, Rainer Machauer, Ulrich Hommel, Clemens Scheufler, Christoph Gaul, César Fernández, Henrik Möbitz, Giorgio Caravatti, Philipp Holzer, Hugh Y. Zhu, Frédéric Stauffer, Ralph Tiedt, Chao Chen

المصدر: ACS Medicinal Chemistry Letters. 8:338-343

مصطلحات موضوعية: 0301 basic medicine, Organic Chemistry, Binding pocket, Context (language use), DOT1L, Biology, Ligand (biochemistry), Biochemistry, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Fragment (logic), 030220 oncology & carcinogenesis, Drug Discovery, Virtual screen, Transferase, Histone methyltransferase DOT1L

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d58f8c53f87935e15045bed1cb72b7
https://doi.org/10.1021/acsmedchemlett.6b00519

المؤلفون: Keiichi Masuya, Stefan Stutz, Vito Guagnano, Philipp Holzer, Robert Mah, Thérèse Stachyra-Valat, Sébastien Jeay, Patrick Chène, Achim Schlapbach, Joerg Kallen, Andrea Vaupel, Pascal Furet, Stephan Ruetz

المصدر: Bioorganic & Medicinal Chemistry Letters. 26:4837-4841

مصطلحات موضوعية: 0301 basic medicine, Class (set theory), Chemistry, Organic Chemistry, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Proto-Oncogene Proteins c-mdm2, Crystallography, X-Ray, Biochemistry, Small molecule, Anticancer drug, Combinatorial chemistry, P53 mdm2, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, 030220 oncology & carcinogenesis, Drug Discovery, Fluorescence Resonance Energy Transfer, Molecular Medicine, Structure based, Tumor Suppressor Protein p53, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b4d362e3cd5c7b8af47f60ef6d2139
https://doi.org/10.1016/j.bmcl.2016.08.010

المؤلفون: Robert Mah, Sébastien Jeay, Milen Todorov, Stephan Ruetz, Caroline Rynn, Stefan Stutz, Philipp Holzer, Pascal Furet, Joerg Kallen, Stephane Ferretti, Therese Stachyra, Achim Schlapbach, Keiichi Masuya, Vito Guagnano, Andrea Vaupel

المصدر: Bioorganicmedicinal chemistry letters. 28(20)

مصطلحات موضوعية: 0301 basic medicine, Male, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Pharmacology, Biochemistry, P53 mdm2, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Dogs, In vivo, Cell Line, Tumor, Drug Discovery, Animals, Humans, Molecular Biology, Organic Chemistry, Rational design, Proto-Oncogene Proteins c-mdm2, Stereoisomerism, Haplorhini, Cell cycle, Small molecule, In vitro, First generation, Pyrrolidinones, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Microsomes, Liver, Molecular Medicine, Pyrazoles, Protein Multimerization, Tumor Suppressor Protein p53, Lead compound

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f34c1be3db54c41b2dec1e6dd750b3
https://pubmed.ncbi.nlm.nih.gov/30217415

المؤلفون: Andrea, Vaupel, Guido, Bold, Alain, De Pover, Thérèse, Stachyra-Valat, Joanna Hergovich, Lisztwan, Joanna, Hergovich-Lisztwan, Joerg, Kallen, Keiichi, Masuya, Pascal, Furet

المصدر: Bioorganic & Medicinal Chemistry Letters. 24:2110-2114

مصطلحات موضوعية: Models, Molecular, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Biochemistry, Non peptide, P53 mdm2, chemistry.chemical_compound, Cell Line, Tumor, Neoplasms, Drug Discovery, Humans, Potency, Imidazole, Protein Interaction Maps, Molecular Biology, Cell Proliferation, biology, Chemistry, Organic Chemistry, Imidazoles, Assay, Proto-Oncogene Proteins c-mdm2, biology.organism_classification, Molecular Medicine, Tetra, Oncology drug, Tumor Suppressor Protein p53

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5137b538554bd1abc01b7cefe8beb5af
https://doi.org/10.1016/j.bmcl.2014.03.039

المؤلفون: Aude Izaac, Stefan Stutz, Patrick Chène, Emmanuelle Wirth, Achim Schlapbach, Keiichi Masuya, François Gessier, Robert Mah, Bahaa Salem, Andrea Vaupel, Therese-Marie Stachyra, Philipp Holzer, Vito Guagnano, Joseph Schoepfer, Pascal Furet, Joerg Kallen, Suzanne Chau

المصدر: ChemMedChem. 14:1304-1304

مصطلحات موضوعية: Pharmacology, Chemical compound, Chemistry, Organic Chemistry, X-ray, Biochemistry, Protein–protein interaction, chemistry.chemical_compound, Crystallography, Front cover, Drug Discovery, X-ray crystallography, Molecular Medicine, General Pharmacology, Toxicology and Pharmaceutics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::efe94a39c43df4c5bdda9b5a4aab3872
https://doi.org/10.1002/cmdc.201900400

المؤلفون: Andrea Vaupel, Diethart Matthies

المصدر: Scopus-Elsevier

مصطلحات موضوعية: Insecta, food.ingredient, Alpine plant, Range (biology), Population, Flowers, Biology, Fluctuating asymmetry, food, Altitude, Animals, education, Ecology, Evolution, Behavior and Systematics, Demography, education.field_of_study, Ecology, Reproduction, Population size, food and beverages, Europe, Logistic Models, Carduus, Seed predation, Seeds, Thistle

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5964aaba7818ed88d6cc4e3dc8c7e338
https://doi.org/10.1890/11-2026.1

المؤلفون: Michel Niklaus, Stefan Stutz, Sébastien Jeay, Robin Alec Fairhurst, Andreas Boos, Vito Guagnano, Frédéric Stauffer, Andrea Vaupel, Clive Mccarthy, Pascal Furet, Wenshuo Lu, Thomas H. Marsilje, Pierre-Yves Michellys, Songchun Jiang, Christian Schnell, Bei Chen

المصدر: Bioorganicmedicinal chemistry letters. 26(8)

مصطلحات موضوعية: 0301 basic medicine, Linsitinib, Clinical Biochemistry, Substituent, Pharmaceutical Science, chemistry.chemical_element, Mice, Nude, Ether, Antineoplastic Agents, Biochemistry, Medicinal chemistry, Receptor, IGF Type 1, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, 0302 clinical medicine, In vivo, Drug Discovery, Moiety, Animals, Humans, Pyrroles, Molecular Biology, Protein Kinase Inhibitors, Cell Proliferation, Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, Imidazoles, Neoplasms, Experimental, Combinatorial chemistry, Xenograft Model Antitumor Assays, 030104 developmental biology, Pyrimidines, chemistry, 030220 oncology & carcinogenesis, Cyclic ether, Pyrazines, Fluorine, NIH 3T3 Cells, Molecular Medicine, Selectivity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::950c6eda14d2facb3928006adfb09da2
https://pubmed.ncbi.nlm.nih.gov/26951753

المؤلفون: Klaus Urbahns, Christoph Gerdes, Klemens Lustig, Beatrix Stelte-Ludwig, Ulf Brüggemeier, Andrea Vaupel, Delf Schmidt, Jörg Keldenich, Markus Albers, Michael Härter, Hideki Tsujishita

المصدر: Bioorganic & Medicinal Chemistry Letters. 17:6151-6154

مصطلحات موضوعية: Models, Molecular, Smooth muscle cell migration, Arginine, Stereochemistry, Clinical Biochemistry, Integrin, Pharmaceutical Science, Squaric acid, Ligands, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Humans, Receptors, Vitronectin, Molecular Biology, Sulfonamides, Binding Sites, Molecular Structure, biology, Cell adhesion molecule, Biphenyl Compounds, Organic Chemistry, Biological activity, Ligand (biochemistry), Protein Structure, Tertiary, chemistry, biology.protein, Molecular Medicine, Vitronectin, Cyclobutanes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ebe513cb3e0218552439673ff3bd1de
https://doi.org/10.1016/j.bmcl.2007.09.039

المؤلفون: Teja Tscharntke, Katrin Klinge, Andrea Vaupel, Roland Brandl, Volker Wissemann, Martin Brändle

المصدر: Biological Journal of the Linnean Society. 90:619-625

مصطلحات موضوعية: 0106 biological sciences, 0303 health sciences, Rhagoletis, biology, Rosa canina, Population genetics, Zoology, biology.organism_classification, 010603 evolutionary biology, 01 natural sciences, 03 medical and health sciences, Tephritidae, Botany, Caninae, Genetic variability, Rosa rubiginosa, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Isolation by distance

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dd73e278812b81bd2f98d53a2567f2f9
https://doi.org/10.1111/j.1095-8312.2007.00751.x