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1
المؤلفون: Robert F. Siliciano, Sarah B. Laskey, Mariela Bollini, Krasimir A. Spasov, Kathleen M. Frey, Karen S. Anderson, Andrea C. Mislak, William L. Jorgensen, William T. Gray, Won-Gil Lee
المصدر: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICETمصطلحات موضوعية: Efavirenz, Resistance, Population, Non-nucleoside reverse transcriptase inhibitors, Biology, medicine.disease_cause, Biochemistry, purl.org/becyt/ford/1 [https], chemistry.chemical_compound, Drug Discovery, purl.org/becyt/ford/1.4 [https], medicine, Transferase, education, chemistry.chemical_classification, Mutation, education.field_of_study, Otras Ciencias Químicas, Organic Chemistry, Ciencias Químicas, HIV, virus diseases, Virology, Reverse transcriptase, Rreverse transcriptase, Discovery and development of non-nucleoside reverse-transcriptase inhibitors, Enzyme, chemistry, Rilpivirine, CIENCIAS NATURALES Y EXACTAS, Mutations
وصف الملف: application/pdf
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2
المؤلفون: Christie K. Shumate, Karen S. Anderson, Sheida Amiralaei, Yuhui Yin, Andrea C. Mislak, Raymond F. Schinazi, Christal D. Sohl, Michal R. Szymanski
المصدر: Proceedings of the National Academy of Sciences. 113
مصطلحات موضوعية: chemistry.chemical_classification, Genetics, Multidisciplinary, chemistry, biology.protein, Nucleotide, Biology, Selectivity, Human mitochondrial genetics, Polymerase
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3
المؤلفون: Lee Warren, Suzanne C. Edavettal, Jacob Marcus, Matthew G. Stanton, Hugh Nuthall, David L. Sloman, Tammy Dellovade, Alexander A. Szewczak, Deborah Walker, Sanjeev Munshi, Andrea C. Mislak, Michael Hutton, Michael D. Altman, Zhenhua Wu, Mansuo Hayashi, Dapeng Chen, Hua-Poo Su, Njamkou Noucti
المصدر: Bioorganicmedicinal chemistry letters. 26(17)
مصطلحات موضوعية: 0301 basic medicine, Clinical Biochemistry, Pharmaceutical Science, Protein Serine-Threonine Kinases, Crystallography, X-Ray, Biochemistry, Pyrazolopyrimidine, Cns penetration, 03 medical and health sciences, chemistry.chemical_compound, Inhibitory Concentration 50, 0302 clinical medicine, Dogs, Microtubule, Heterocyclic Compounds, Drug Discovery, medicine, Potency, Animals, Humans, Enzyme Inhibitors, Molecular Biology, Improved solubility, Kinase, Organic Chemistry, Neurofibrillary tangle, medicine.disease, Rats, Enzyme Activation, Molecular Weight, 030104 developmental biology, chemistry, Solubility, Molecular Medicine, Efflux, 030217 neurology & neurosurgery
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4
المؤلفون: Karen S. Anderson, Andrea C. Mislak
المصدر: Antimicrobial agents and chemotherapy. 60(1)
مصطلحات موضوعية: 0301 basic medicine, Anti-HIV Agents, Gene Expression, DNA Primase, DNA-Directed DNA Polymerase, Biology, Antiviral Agents, Nucleoside Reverse Transcriptase Inhibitor, Polymerization, 03 medical and health sciences, chemistry.chemical_compound, Deoxyadenine Nucleotides, Escherichia coli, Humans, Pharmacology (medical), Nucleotide, Cloning, Molecular, Polymerase, Pharmacology, chemistry.chemical_classification, RNA, virus diseases, Deoxyguanine Nucleotides, DNA, Multifunctional Enzymes, Recombinant Proteins, Kinetics, 030104 developmental biology, Infectious Diseases, chemistry, Biochemistry, Deoxycytosine Nucleotides, biology.protein, Reverse Transcriptase Inhibitors, Primase, Thymidine, Nucleoside, Protein Binding
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5
المؤلفون: Sheida Amiralaei, Andrea C. Mislak, Y. Whitney Yin, Christie K. Shumate, Karen S. Anderson, Raymond F. Schinazi, Michal R. Szymanski, Christal D. Sohl
مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, DNA-Directed DNA Polymerase, Emtricitabine, Crystallography, X-Ray, Human mitochondrial genetics, Corrections, Nucleoside Reverse Transcriptase Inhibitor, Substrate Specificity, 03 medical and health sciences, immune system diseases, medicine, Humans, Polymerase, Nucleic Acid Synthesis Inhibitors, Multidisciplinary, biology, virus diseases, Biological Sciences, medicine.disease, Molecular biology, Reverse transcriptase, DNA Polymerase gamma, Mitochondria, Mitochondrial toxicity, Kinetics, 030104 developmental biology, Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors, Molecular Probes, biology.protein, Reverse Transcriptase Inhibitors, Nucleoside, medicine.drug
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6
المؤلفون: Karen S. Anderson, Andrea C. Mislak
المصدر: The FASEB Journal. 29
مصطلحات موضوعية: immune system diseases, Mechanism (biology), Chemistry, Toxicity, Genetics, virus diseases, Molecular Biology, Biochemistry, Virology, Biotechnology, Nucleoside Reverse Transcriptase Inhibitor
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7
المؤلفون: William L. Jorgensen, Kathleen M. Frey, Karen S. Anderson, Mariela Bollini, Andrea C. Mislak
المصدر: Biochimica et biophysica acta. 1840(7)
مصطلحات موضوعية: NNRTI, Drug, Stereochemistry, Protein Conformation, media_common.quotation_subject, Morpholines, Biophysics, Substituent, HIV Infections, Biology, Crystallography, X-Ray, Biochemistry, Article, chemistry.chemical_compound, Protein structure, Morpholine, Humans, Molecular Biology, media_common, Mechanical Phenomena, REVERSE TRANSCRIPTASE, Triazines, CRYSTALLOGRAPHY, Otras Ciencias Químicas, Ciencias Químicas, Reverse transcriptase, HIV Reverse Transcriptase, Azine, Solvent, Kinetics, chemistry, Drug Design, TRANSIENT KINETICS, HIV-1, Reverse Transcriptase Inhibitors, Primer (molecular biology), CIENCIAS NATURALES Y EXACTAS
وصف الملف: application/pdf
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8
المؤلفون: Yagmur Muftuoglu, Stefan G. Sarafianos, Hiroaki Mitsuya, Christal D. Sohl, Andrea C. Mislak, Karen S. Anderson
المصدر: Antiviral research. 106
مصطلحات موضوعية: Anti-HIV Agents, Article, chemistry.chemical_compound, Deoxyadenosine, Virology, medicine, Nucleotide, Enzyme kinetics, Polymerase, Pharmacology, chemistry.chemical_classification, Reverse-transcriptase inhibitor, biology, Deoxyadenosines, Molecular biology, Reverse transcriptase, HIV Reverse Transcriptase, Kinetics, chemistry, biology.protein, HIV-1, Reverse Transcriptase Inhibitors, Primer (molecular biology), Nucleoside, medicine.drug
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9
المؤلفون: Ricardo Gallardo-Macias, José A. Cisneros, Karen S. Anderson, Andrea C. Mislak, Kathleen M. Frey, Mariela Bollini, William L. Jorgensen
مصطلحات موضوعية: Drug, Models, Molecular, Stereochemistry, media_common.quotation_subject, Human immunodeficiency virus (HIV), Crystal structure, medicine.disease_cause, Crystallography, X-Ray, Biochemistry, Antiviral Agents, Catalysis, Article, Inhibitory Concentration 50, Colloid and Surface Chemistry, Halogens, medicine, Humans, media_common, Halogen bond, Chemistry, Hydrogen Bonding, General Chemistry, Bromine, Reverse transcriptase, HIV Reverse Transcriptase, Drug Design, Reverse Transcriptase Inhibitors