المؤلفون: Luke Buerer, Nathaniel E. Clark, Anastasia Welch, Chaorui Duan, Allison J. Taggart, Brittany A. Townley, Jing Wang, Rachel Soemedi, Stephen Rong, Chien-Ling Lin, Yi Zeng, Adam Katolik, Jonathan P. Staley, Masad J. Damha, Nima Mosammaparast, William G. Fairbrother

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/81ba1794519b409e80b2dd49a5ba6bff

المؤلفون: Nathaniel E. Clark (1508023), Adam Katolik (1508029), Anastasia Welch (14241127), Christoph Schorl (151201), Stephen P. Holloway (815903), Jonathan P. Schuermann (2379397), P. John Hart (815904), Alexander B. Taylor (815897), Masad J. Damha (12132), William G. Fairbrother (11415494)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Molecular Biology, Pharmacology, Biotechnology, Immunology, Hematology, Infectious Diseases, Chemical Sciences not elsewhere classified, sole enzyme responsible, rates ∼ 10, native phosphate linkages, modification commonly used, als ), cancer, aid inhibitor design, rna lariats produced, hydrolyze branched rnas, human immunodeficiency virus, native brna substrate, dbr1 inhibitors could, branched rna, human diseases, viral encephalitis, resist degradation, kinetic mechanism, investigative compounds, findings suggest, crystal structure

Relation: https://figshare.com/articles/journal_contribution/Crystal_Structure_of_the_RNA_Lariat_Debranching_Enzyme_Dbr1_with_Hydrolyzed_Phosphorothioate_RNA_Product/21703420

الاتاحة: https://doi.org/10.1021/acs.biochem.2c00590.s001

المؤلفون: Stephen Rong, Christopher R. Neil, Anastasia Welch, Chaorui Duan, Samantha Maguire, Ijeoma C. Meremikwu, Malcolm Meyerson, Ben J. Evans, William G. Fairbrother

المصدر: Proceedings of the National Academy of Sciences. 120

مصطلحات موضوعية: Multidisciplinary

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::962145bc4d0246089c4f527d33921673
https://doi.org/10.1073/pnas.2218308120

المؤلفون: Nathaniel E. Clark, Adam Katolik, Anastasia Welch, Christoph Schorl, Stephen P. Holloway, Jonathan P. Schuermann, P. John Hart, Alexander B. Taylor, Masad J. Damha, William G. Fairbrother

المصدر: Biochemistry

مصطلحات موضوعية: RNA Splicing, Humans, RNA, RNA Nucleotidyltransferases, Biochemistry, Article, Phosphates

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f67fef474ead4eaa9bf0c6612c34fee
https://europepmc.org/articles/PMC10308451/