المؤلفون: Stanislav A. Petrov, Aleksei E. Machulkin, Anastasia A. Uspenskaya, Nikolay Y. Zyk, Ekaterina A. Nimenko, Anastasia S. Garanina, Rostislav A. Petrov, Vladimir I. Polshakov, Yuri K. Grishin, Vitaly A. Roznyatovsky, Nikolay V. Zyk, Alexander G. Majouga, Elena K. Beloglazkina

المصدر: Molecules, Vol 25, Iss 24, p 5784 (2020)

مصطلحات موضوعية: theranostic agent, peptide synthesis, prostate cancer, anticancer drugs, PSMA conjugate, docetaxel, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/24/5784; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/ae00a4fa5629496f8c958afc95c1484f

المؤلفون: Nikolai Y. Zyk, Anton P. Ber, Ekaterina A. Nimenko, Radik R. Shafikov, Sergei A. Evteev, Stanislav A. Petrov, Anastasia A. Uspenskaya, Natalia S. Dashkova, Yan A. Ivanenkov, Dmitry A. Skvortsov, Elena K. Beloglazkina, Alexander G. Majouga, Aleksei E. Machulkin

المصدر: Bioorganicmedicinal chemistry letters. 71

مصطلحات موضوعية: Glutamate Carboxypeptidase II, Male, Nitrogen, Lysine, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Prostatic Neoplasms, Ligands, Biochemistry, Cell Line, Tumor, Drug Discovery, Antigens, Surface, Molecular Medicine, Humans, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d17b688770307a916c16864578d519
https://pubmed.ncbi.nlm.nih.gov/35661685

المؤلفون: Vasilii Kolmogorov, Elena S. Khazanova, Yan A. Ivanenkov, Sergei V. Kovalev, Nikolay V. Zyk, Anastasia A. Uspenskaya, Alexander G. Majouga, Petr V. Gorelkin, Stanislav A. Petrov, Radik R. Shafikov, Anton P. Ber, Yulia A. Borisova, Dmitry A. Skvortsov, Ekaterina A. Nimenko, Vadim S. Pokrovsky, Elena K. Beloglazkina, Alexander Vaneev, Nikolay Y. Zyk, Alexander Erofeev, Alexander D. Khudyakov, Galina B. Smirnova, Aleksei E. Machulkin

المصدر: European journal of medicinal chemistry. 227

مصطلحات موضوعية: Male, Antineoplastic Agents, Docetaxel, Pharmacology, urologic and male genital diseases, Small Molecule Libraries, Mice, Structure-Activity Relationship, Pharmacokinetics, In vivo, Cell Line, Tumor, Drug Discovery, medicine, Glutamate carboxypeptidase II, Distribution (pharmacology), Animals, Humans, MTT assay, Rats, Wistar, Cell Proliferation, Mice, Inbred ICR, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, General Medicine, Neoplasms, Experimental, Prostate-Specific Antigen, Rats, Drug delivery, Rabbits, Drug Screening Assays, Antitumor, medicine.drug, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62a1b68e92171082e1b27fd3d99713c
https://pubmed.ncbi.nlm.nih.gov/34717125

المؤلفون: Elena K. Beloglazkina, Anastasia A. Uspenskaya, A. G. Mazhuga, Alexey E. Machulkin

المصدر: Pharmaceutical Chemistry Journal. 53:288-297

مصطلحات موضوعية: Pharmacology, Drug, 010405 organic chemistry, Chemistry, media_common.quotation_subject, Pharmacology toxicology, Biological activity, urologic and male genital diseases, medicine.disease, 01 natural sciences, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Prostate cancer, Drug Discovery, Glutamate carboxypeptidase II, medicine, Cancer research, Linker, media_common, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c56da76f2cc34e094138825aaab3ac6c
https://doi.org/10.1007/s11094-019-01994-1

المؤلفون: Nikolay V. Zyk, Irina V. Saltykova, Anastasiya V Aladinskaya, Alexander Erofeev, Olga O. Krasnovskaya, Radik R. Shafikov, Elena K. Beloglazkina, Anastasiia S Garanina, Oleg Yu. Saveliev, Maxim A. Abakumov, Vladimir I. Polshakov, Ekaterina A. Nimenko, Yan A. Ivanenkov, Aleksei E. Machulkin, Olga A. Dontsova, Emil U Yamansarov, Alexander G. Majouga, Elena S. Khazanova, Anastasia A. Uspenskaya, Anton P. Ber, Galina B. Smirnova, Vadim S. Pokrovsky, Nikolay U. Zyk, Dmitry A. Skvortsov, Petr V. Gorelkin, Stanislav A. Petrov, A. V. Finko, Rauf T Akhmirov

المصدر: Journal of medicinal chemistry. 64(8)

مصطلحات موضوعية: Glutamate Carboxypeptidase II, Male, Cell Survival, Transplantation, Heterologous, Mice, Nude, Antineoplastic Agents, urologic and male genital diseases, Ligands, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Cell Line, Tumor, Drug Discovery, Glutamate carboxypeptidase II, Aromatic amino acids, Structure–activity relationship, Animals, Humans, Tissue Distribution, 030304 developmental biology, Fluorescent Dyes, 0303 health sciences, Ligand, Chemistry, Optical Imaging, Prostatic Neoplasms, In vitro, 0104 chemical sciences, Transplantation, 010404 medicinal & biomolecular chemistry, Biochemistry, Antigens, Surface, Molecular Medicine, Drug Screening Assays, Antitumor, Linker, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb2bdb39740f4dc14b677c9a847824bf
https://pubmed.ncbi.nlm.nih.gov/33822606

المؤلفون: Aleksei E. Machulkin, Alexander G. Majouga, Ekaterina A. Nimenko, Anastasia A. Uspenskaya, Elena K. Beloglazkina

المصدر: Current medicinal chemistry. 29(2)

مصطلحات موضوعية: Male, Computational biology, Ligands, Biochemistry, chemistry.chemical_compound, Prostate cancer, Structure-Activity Relationship, Drug Delivery Systems, Cell Line, Tumor, Drug Discovery, medicine, Glutamate carboxypeptidase II, Humans, Pharmacology, Dipeptide, Organic Chemistry, Cancer, Prostatic Neoplasms, Biological activity, medicine.disease, Targeted drug delivery, chemistry, Molecular Medicine, Peptides, Linker, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea866f4daef8b8bed4466d6a88249dd
https://pubmed.ncbi.nlm.nih.gov/34348608

المؤلفون: Nikolay V. Zyk, Anastasia S. Garanina, Anastasia A. Uspenskaya, Yuri K. Grishin, Aleksei E. Machulkin, Vladimir I. Polshakov, Ekaterina A. Nimenko, Rostislav A Petrov, Nikolay Y. Zyk, Vitaly A. Roznyatovsky, Stanislav A. Petrov, Elena K. Beloglazkina, Alexander G. Majouga

المصدر: Molecules, Vol 25, Iss 5784, p 5784 (2020)
Molecules
Volume 25
Issue 24

مصطلحات موضوعية: Glutamate Carboxypeptidase II, Pharmaceutical Science, Chemistry Techniques, Synthetic, Tripeptide, PSMA conjugate, 01 natural sciences, Article, Analytical Chemistry, lcsh:QD241-441, 03 medical and health sciences, chemistry.chemical_compound, Drug Delivery Systems, 0302 clinical medicine, lcsh:Organic chemistry, Amide, Drug Discovery, peptide synthesis, Glutamate carboxypeptidase II, Peptide synthesis, Moiety, docetaxel, Amino Acid Sequence, Physical and Theoretical Chemistry, Drug Carriers, Molecular Structure, 010405 organic chemistry, Organic Chemistry, Carbocyanines, prostate cancer, Combinatorial chemistry, 0104 chemical sciences, Sulfo-Cy5, theranostic agent, anticancer drugs, chemistry, Chemistry (miscellaneous), 030220 oncology & carcinogenesis, Antigens, Surface, Molecular Medicine, Azide, Peptides, Linker, Conjugate

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e065d108521f08232fbbde0a416c3af
https://www.mdpi.com/1420-3049/25/24/5784

المؤلفون: E. A. Plotnikova, Raisa I. Yakubovskaya, Nikolay U. Zyk, Yan A. Ivanenkov, Mikhail V. Kavalchuk, Elena K. Beloglazkina, Anastasia V. Aladinskaya, Alexander G. Majouga, Victor Koteliansky, Alexey E. Machulkin, Ekaterina A. Nimenko, Dmitry A. Skvortsov, Nikolay V. Zyk, Anton P. Ber, Radik R. Shafikov, Anastasia A. Uspenskaya

المصدر: Bioorganicmedicinal chemistry letters. 29(16)

مصطلحات موضوعية: Male, Paclitaxel, Clinical Biochemistry, Pharmaceutical Science, 01 natural sciences, Biochemistry, Prostate cancer, chemistry.chemical_compound, Mice, Drug Delivery Systems, Prostate, Drug Discovery, LNCaP, medicine, Glutamate carboxypeptidase II, Animals, Humans, Cytotoxicity, Molecular Biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Prostatic Neoplasms, medicine.disease, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, medicine.anatomical_structure, Targeted drug delivery, Drug delivery, Cancer research, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4714c764aee1e4f4569241a2018a3f2e
https://pubmed.ncbi.nlm.nih.gov/31248772

المؤلفون: Nataliya S. Vorobyeva, Alexey E. Machulkin, Elena K. Beloglazkina, A. V. Trofimenko, Alexander G. Majouga, Victor Koteliansky, Ekaterina V. Deyneka, Alina A. Sofronova, Dmitry S. Bezrukov, Yan A. Ivanenkov, Anastasia V. Aladinskaya, Maria M Puchinina, Alexander S. Malyshev, Grigory K. Riabykh, Anastasia A. Uspenskaya, Nikolay V. Zyk, Dmitry A. Skvortsov, Anastasia S. Garanina

المصدر: Bioorganicmedicinal chemistry letters. 29(10)

مصطلحات موضوعية: Glutamate Carboxypeptidase II, Male, Cell Survival, Clinical Biochemistry, Transplantation, Heterologous, Pharmaceutical Science, Antineoplastic Agents, Ligands, 01 natural sciences, Biochemistry, Mice, In vivo, Cell Line, Tumor, Drug Discovery, medicine, Glutamate carboxypeptidase II, Cytotoxic T cell, Animals, Humans, Doxorubicin, Molecular Biology, Cell Nucleus, Binding Sites, 010405 organic chemistry, Chemistry, Organic Chemistry, Prostatic Neoplasms, 0104 chemical sciences, Protein Structure, Tertiary, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, Targeted drug delivery, Cancer cell, Antigens, Surface, Biophysics, Molecular Medicine, Linker, Conjugate, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13581cc69a300a79a1bf2eedf7004483
https://pubmed.ncbi.nlm.nih.gov/31056242

المؤلفون: Aleksei E. Machulkin (10530799), Radik R. Shafikov (9541210), Anastasia A. Uspenskaya (10530802), Stanislav A. Petrov (10530805), Anton P. Ber (10530808), Dmitry A. Skvortsov (1773577), Ekaterina A. Nimenko (10530811), Nikolay U. Zyk (10530814), Galina B. Smirnova (10530817), Vadim S. Pokrovsky (4163365), Maxim A. Abakumov (4691245), Irina V. Saltykova (7505030), Rauf T. Akhmirov (10530820), Anastasiia S. Garanina (6998078), Vladimir I. Polshakov (1277577), Oleg Y. Saveliev (10530823), Yan A. Ivanenkov (1745152), Anastasiya V. Aladinskaya (10530826), Alexander V. Finko (6681806), Emil U. Yamansarov (10530829), Olga O. Krasnovskaya (1773565), Alexander S. Erofeev (1853785), Petr V. Gorelkin (1853770), Olga A. Dontsova (7313015), Elena K. Beloglazkina (1773589), Nikolay V. Zyk (1773586), Elena S. Khazanova (10530832), Alexander G. Majouga (1773604)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Chemical Sciences not elsewhere classified, PSMA Ligands, Biological Evaluation, prostate cancer cells, SulfoCy 7, glutamate carboxypeptidase II, Fluorescent Conjugates, linker structure, Prostate-specific membrane antigen, antitumor drugs, PSMA-SulfoCy 7 conjugates, novel low-molecular PSMA ligands, conjugate PSMA-SulfoCy 7, novel PSMA ligand, vivo biodistribution, SulfoCy 5, 22 Rv 1 xenografts, PSMA-expressing tumors, PSMA-expressing tumor cells, GCPII, FAM, Aromatic Residues

Relation: https://figshare.com/articles/journal_contribution/Synthesis_and_Biological_Evaluation_of_PSMA_Ligands_with_Aromatic_Residues_and_Fluorescent_Conjugates_Based_on_Them/14377273

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c01935.s001