المؤلفون: Evelien Van Dijck, Sara Diels, Erik Fransen, Tycho Canter Cremers, An Verrijken, Eveline Dirinck, Alexander Hoischen, Geert Vandeweyer, Wim Vanden Berghe, Luc Van Gaal, Sven Francque, Wim Van Hul

المصدر: Antioxidants, Vol 13, Iss 9, p 1051 (2024)

مصطلحات موضوعية: obesity, metabolic dysfunction associated steatotic liver disease (MASLD), paraoxonase (PON), genetics, antioxidants, oxidative stress, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2076-3921/13/9/1051; https://doaj.org/toc/2076-3921

URL الوصول: https://doaj.org/article/3610f4d5206345fe9f8499759c900757

المؤلفون: Guillaume Grzych, Oscar Chávez-Talavera, Amandine Descat, Dorothée Thuillier, An Verrijken, Mostafa Kouach, Vanessa Legry, Hélène Verkindt, Violeta Raverdy, Benjamin Legendre, Robert Caiazzo, Luc Van Gaal, Jean-Francois Goossens, Réjane Paumelle, Sven Francque, François Pattou, Joel T. Haas, Anne Tailleux, Bart Staels

المصدر: JHEP Reports, Vol 3, Iss 2, Pp 100222- (2021)

مصطلحات موضوعية: NASH, NAFLD, Bile acids, Diabetes, Insulin resistance, Obesity, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555920301567; https://doaj.org/toc/2589-5559

URL الوصول: https://doaj.org/article/86f4e08dfca4419c8dc1e4b25ab23c55

المؤلفون: Sara Diels, Sander Huybreghts, Kim Van Hoorenbeeck, Guy Massa, An Verrijken, Stijn L. Verhulst, Luc F. Van Gaal, Wim Van Hul

المصدر: Molecular Genetics and Metabolism Reports, Vol 25, Iss , Pp 100656- (2020)

مصطلحات موضوعية: Obesity, Olfactory receptor, Copy number variant, Chromosome 11q11, Expression profiling, Medicine (General), R5-920, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2214426920301026; https://doaj.org/toc/2214-4269

URL الوصول: https://doaj.org/article/b49b7fab0d3d4189954827a4d3cd3bb6

المؤلفون: Abraham S. Meijnikman, Christophe E. M. De Block, An Verrijken, Ilse Mertens, Luc F. Van Gaal

المصدر: Diabetology & Metabolic Syndrome, Vol 10, Iss 1, Pp 1-6 (2018)

مصطلحات موضوعية: Type 2 diabetes mellitus, Prediabetes, Screening, Metabolic syndrome, FINDRISC, Obesity, Nutritional diseases. Deficiency diseases, RC620-627

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13098-018-0310-0; https://doaj.org/toc/1758-5996

URL الوصول: https://doaj.org/article/f93a50b7761a4f46a30d42512a7c89e6

المؤلفون: Wim Verlinden, Eugénie Van Mieghem, Laura Depauw, Thomas Vanwolleghem, Luisa Vonghia, Jonas Weyler, Ann Driessen, Dirk Callens, Laurence Roosens, Eveline Dirinck, An Verrijken, Luc Van Gaal, Sven Francque

المصدر: Biomedicines, Vol 8, Iss 12, p 546 (2020)

مصطلحات موضوعية: NASH, steatohepatitis, aminopyrine, microsomal, liver function, breath test, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2227-9059/8/12/546; https://doaj.org/toc/2227-9059

URL الوصول: https://doaj.org/article/05ac3ce96c48437f99bd6ec6e195f348

المؤلفون: Kaat Kehoe, Heidi Noels, Wendy Theelen, Emilie De Hert, Shenguan Xu, An Verrijken, Thierry Arnould, Erik Fransen, Nina Hermans, Anne-Marie Lambeir, Per Venge, Luc Van Gaal, Ingrid De Meester

المصدر: PLoS ONE, Vol 13, Iss 5, p e0197603 (2018)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5957431?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/2dd0dc721c3b40a0b8ef9ddacedea1a4

المؤلفون: Johannie du Plessis, Hannelie Korf, Jos van Pelt, Petra Windmolders, Ingrid Vander Elst, An Verrijken, Guy Hubens, Luc Van Gaal, David Cassiman, Frederik Nevens, Sven Francque, Schalk van der Merwe

المصدر: PLoS ONE, Vol 11, Iss 12, p e0166048 (2016)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5167229?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/09ae9032fcc841519ef5a4b7cac0408d

المؤلفون: Luisa Vonghia, Thea Magrone, An Verrijken, Peter Michielsen, Luc Van Gaal, Emilio Jirillo, Sven Francque

المصدر: PLoS ONE, Vol 10, Iss 11, p e0143380 (2015)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4658042?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/9de71adf7c234007ad8552db186fa6e2

المؤلفون: Giovanni Musso, Roberto Gambino, James H Tabibian, Mattias Ekstedt, Stergios Kechagias, Masahide Hamaguchi, Rolf Hultcrantz, Hannes Hagström, Seung Kew Yoon, Phunchai Charatcharoenwitthaya, Jacob George, Francisco Barrera, Svanhildur Hafliðadóttir, Einar Stefan Björnsson, Matthew J Armstrong, Laurence J Hopkins, Xin Gao, Sven Francque, An Verrijken, Yusuf Yilmaz, Keith D Lindor, Michael Charlton, Robin Haring, Markus M Lerch, Rainer Rettig, Henry Völzke, Seungho Ryu, Guolin Li, Linda L Wong, Mariana Machado, Helena Cortez-Pinto, Kohichiroh Yasui, Maurizio Cassader

المصدر: PLoS Medicine, Vol 11, Iss 7, p e1001680 (2014)

مصطلحات موضوعية: Medicine

وصف الملف: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25050550/pdf/?tool=EBI; https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676

URL الوصول: https://doaj.org/article/3fdb5f1914e441bd9e84c0b5170f460b

المؤلفون: Margot Berings, Charline Wehlou, An Verrijken, Ellen Deschepper, Ilse Mertens, Jean-Marc Kaufman, Luc F Van Gaal, D Margriet Ouwens, Johannes B Ruige

المصدر: PLoS ONE, Vol 7, Iss 9, p e45145 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3460993?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/d56facb12d0448999eac3ec74622373f

المؤلفون: Vacca M., Kamzolas I., Harder L. M., Oakley F., Trautwein C., Hatting M., Ross T., Bernardo B., Oldenburger A., Hjuler S. T., Ksiazek I., Linden D., Schuppan D., Rodriguez-Cuenca S., Tonini M. M., Castaneda T. R., Kannt A., Rodrigues C. M. P., Cockell S., Govaere O., Daly A. K., Allison M., Honnens de Lichtenberg K., Kim Y. O., Lindblom A., Oldham S., Andreasson A. -C., Schlerman F., Marioneaux J., Sanyal A., Afonso M. B., Younes R., Amano Y., Friedman S. L., Wang S., Bhattacharya D., Simon E., Paradis V., Burt A., Grypari I. M., Davies S., Driessen A., Yashiro H., Pors S., Worm Andersen M., Feigh M., Yunis C., Bedossa P., Stewart M., Cater H. L., Wells S., Schattenberg J. M., Anstee Q. M., Tiniakos D., Perfield J. W., Petsalaki E., Davidsen P., Vidal-Puig A., Cordell H. J., Day C. P., Wonders K., Missier P., McTeer M., Vale L., Oluboyede Y., Breckons M., Boyle J., Bossuyt P. M., Zafarmand H., Vali Y., Lee J., Nieuwdorp M., Holleboom A. G., Angelakis A., Verheij J., Ratziu V., Clement K., Patino-Navarrete R., Pais R., Surabattula R., Myneni S., Straub B. K., Rodrigues-Cuenca S., Campbell M., Lelliott C. J., Oresic M., Hyotylainen T., McGlinchey A., Mato J. M., Millet O., Dufour J. -F., Berzigotti A., Masoodi M., Lange N. F., Pavlides M., Harrison S., Neubauer S., Cobbold J., Mozes F., Akhtar S., Olodo-Atitebi S., Banerjee R., Shumbayawonda E., Dennis A., Andersson A., Wigley I., Romero-Gomez M., Gomez-Gonzalez E., Ampuero J., Castell J., Gallego-Duran R., Fernandez-Lizaranzu I., Montero-Vallejo R., Karsdal M., Rasmussen D. G. K., Leeming D. J., Sinisi A., Musa K., Sandt E., Bugianesi E., Rosso C., Armandi A., Marra F., Gastaldelli A., Svegliati G., Boursier J., Francque S., Vonghia L., Verrijken A., Dirinck E., Ekstedt M., Kechagias S., Yki-Jarvinen H., Porthan K., Arola J., van Mil S., Papatheodoridis G., Cortez-Pinto H., Silva A. P., Valenti L., Pelusi S., Petta S., Pennisi G., Miele L., Liguori A., Geier A., Rau M., Reissing J., Aithal G. P., Francis S., Palaniyappan N., Bradley C., Hockings P., Schneider M., Newsome P. N., Hubscher S., Wenn D., Magnanensi J., Trylesinski A., Mayo R., Alonso C., Duffin K., Chen Y., Hartman M. L., Miller M., McLeod E. J., Scholch C., Ertle J., Coxson H., Gogain J., Ostroff R., Alexander L., Biegel H., Kjaer M. S., Al-Sari N., Veidal S. S., Ellegaard J., Balp M. -M., Jennings L., Martic M., Loffler J., Applegate D., Torstenson R., Fournier-Poizat C., Llorca A., Kalutkiewicz M., Pepin K., Ehman R., Horan G., Ho G., Tai D., Chng E., Xiao T., Patterson S. D., Billin A., Doward L., Twiss J., Thakker P., Derdak Z., Landgren H., Lackner C., Gouw A., Hytiroglou P., Brass C.

المساهمون: Vacca M., Kamzolas I., Harder L.M., Oakley F., Trautwein C., Hatting M., Ross T., Bernardo B., Oldenburger A., Hjuler S.T., Ksiazek I., Linden D., Schuppan D., Rodriguez-Cuenca S., Tonini M.M., Castaneda T.R., Kannt A., Rodrigues C.M.P., Cockell S., Govaere O., Daly A.K., Allison M., Honnens de Lichtenberg K., Kim Y.O., Lindblom A., Oldham S., Andreasson A.-C., Schlerman F., Marioneaux J., Sanyal A., Afonso M.B., Younes R., Amano Y., Friedman S.L., Wang S., Bhattacharya D., Simon E., Paradis V., Burt A., Grypari I.M., Davies S., Driessen A., Yashiro H., Pors S., Worm Andersen M., Feigh M., Yunis C., Bedossa P., Stewart M., Cater H.L., Wells S., Schattenberg J.M., Anstee Q.M., Tiniakos D., Perfield J.W., Petsalaki E., Davidsen P., Vidal-Puig A., Cordell H.J., Day C.P., Wonders K., Missier P., McTeer M., Vale L., Oluboyede Y., Breckons M., Boyle J., Bossuyt P.M., Zafarmand H., Vali Y., Lee J., Nieuwdorp M., Holleboom A.G., Angelakis A., Verheij J., Ratziu V., Clement K., Patino-Navarrete R., Pais R., Surabattula R., Myneni S., Straub B.K., Rodrigues-Cuenca S., Campbell M.

مصطلحات موضوعية: steatosis, MASH, MASLD, murine models

Relation: info:eu-repo/semantics/altIdentifier/pmid/38867022; volume:6; issue:6; firstpage:1178; lastpage:1196; numberofpages:19; journal:NATURE METABOLISM; https://hdl.handle.net/10447/653999

الاتاحة: https://hdl.handle.net/10447/653999
https://doi.org/10.1038/s42255-024-01043-6

المؤلفون: Peleman, Cédric, Hellemans, Stig, Veeckmans, Geraldine, Arras, Wout, Zheng, Hao, Koeken, Ine, Van San, Emily, Hassannia, Behrouz, Walravens, Magali, Kayirangwa, Edissa, Beyene, Nateneal Tamerat, Van Herck, Mikhaïl Alfons, De Vos, Winnok Harald, Pintelon, Isabel, van Nassauw, Luc, Oosterlinck, Baptiste, Smet, Annemieke, Vits, Lieve, Dirinck, Eveline, Verrijken, An, De Man, Joris, Van Eyck, Annelies, Kwanten, Wilhelmus Josephus, Vonghia, Luisa, Driessen, Ann, Augustyns, Koen, Toyokuni, Shinya, De Winter, Benedicte, Van Steenkiste, Christophe, Francque, Sven, Vanden Berghe, Tom

المصدر: CELL DEATH AND DIFFERENTIATION ; ISSN: 1350-9047 ; ISSN: 1476-5403

مصطلحات موضوعية: Biology and Life Sciences, Medicine and Health Sciences, LIPID-PEROXIDATION, OXIDATIVE STRESS, CELL-DEATH, GLUTATHIONE-PEROXIDASE-4, ACTIVATION, MECHANISMS

وصف الملف: application/pdf

Relation: https://biblio.ugent.be/publication/01J7E19FV8M2KKHRA1PVSZJGYP; https://biblio.ugent.be/publication/01J7E19FV8M2KKHRA1PVSZJGYP/file/01J7E1H69YQP9NQWHD7P6KBB33

الاتاحة: https://biblio.ugent.be/publication/01J7E19FV8M2KKHRA1PVSZJGYP
http://hdl.handle.net/1854/LU-01J7E19FV8M2KKHRA1PVSZJGYP
https://doi.org/10.1038/s41418-024-01348-9
https://biblio.ugent.be/publication/01J7E19FV8M2KKHRA1PVSZJGYP/file/01J7E1H69YQP9NQWHD7P6KBB33

المؤلفون: van Kleef, Laurens A., Francque, Sven M., Prieto-Ortiz, Jhon E., Sonneveld, Milan J., Sanchez-Luque, Carlos B., Prieto-Ortiz, Robin G., Kwanten, Wilhelmus J., Vonghia, Luisa, Verrijken, An, De Block, Christophe, Gadi, Zouhir, Janssen, Harry L.A., de Knegt, Robert J., Brouwer, Willem Pieter

المصدر: van Kleef , L A , Francque , S M , Prieto-Ortiz , J E , Sonneveld , M J , Sanchez-Luque , C B , Prieto-Ortiz , R G , Kwanten , W J , Vonghia , L , Verrijken , A , De Block , C , Gadi , Z , Janssen , H L A , de Knegt , R J & Brouwer , W P 2024 , ' Metabolic Dysfunction–Associated Fibrosis 5 (MAF-5) Score Predicts Liver Fibrosis Risk and Outcome in the General Population With Metabolic Dysfunction ' , Gastroenterology , vol. 167 , no. ....

مصطلحات موضوعية: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

الاتاحة: https://pure.eur.nl/en/publications/6a4588bb-8948-4d3d-b528-a699f2ac1a92
https://doi.org/10.1053/j.gastro.2024.03.017
https://pure.eur.nl/ws/files/153405094/1-s2.0-S0016508524003007-main.pdf
http://www.scopus.com/inward/record.url?scp=85194091825&partnerID=8YFLogxK

المؤلفون: Clavreul, Ludivine, Bernard, Lucie, Cotte, Alexia, K, Hennuyer, Nathalie, Bourouh, Cyril, Devos, Claire, Helleboid, Audrey, Haas, Joel, T, Verrijken, An, Gheeraert, Céline, Derudas, Bruno, Guille, Loïc, Chevalier, Julie, Eeckhoute, Jérôme, Vallez, Emmanuelle, Dorchies, Emilie, van Gaal, Luc, Lassailly, Guillaume, Francque, Sven, Staels, Bart, Paumelle, Réjane

المساهمون: Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U 1011 (RNMCD), Institut Pasteur de Lille, Pasteur Network (Réseau International des Instituts Pasteur)-Pasteur Network (Réseau International des Instituts Pasteur)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Institut Européen de Génomique du Diabète - European Genomic Institute for Diabetes - FR 3508 (EGID), Pasteur Network (Réseau International des Instituts Pasteur)-Pasteur Network (Réseau International des Instituts Pasteur)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), University of Antwerp (UA), Institute for Translational Research in Inflammation - U 1286 (INFINITE), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), This work was supported by: the Nouvelle Societe Française d’Atherosclerose (NSFA, to LC), the FP7 “RESOLVE” (Grant ID: 305707 to BS, AV, SF, LVG) by FP6 “HEPADIP” (Contract LSHM-CT-2005-018734 to SF, LVG, BS), the European Genomic Institute for Diabetes (EGID, ANR10-LABX-0046 to BS), the Agence Nationale de la Recherche (ANR) PreciNASH (ANR-16-RHUS-0006 to BS), DeCodeNASH (ANR-20-CE14-0034 to JTH), the Fondation pour la Recherche Medicale (EQU202203014650), the Association Française pour l’Etude du Foie (AFEF, to RP), the Contrat Plan Etat-Region Hauts-de-France-Centre Transdisciplinaire de la Recherche sur la Longevite (CPER-CTRL) (to RP, AC and LB), an ERC Starting Grant (Metabo3DC no.101042759) (to JTH) and France Relance (ANR-21-PRRD-0076-01 to RP, BS, CB and CD). LC was supported by a PhD fellowship from Institut Pasteur de Lille and Région Haut de France (France). LB was supported by a PhD fellowship from Centre Hospitalier Universitaire (CHU) de Lille and by the "Health PhD 2020" scolarship of I-Site Universit´e de Lille Nord Europe (ULNE) (France). JTH was supported by an EMBO Long Term Fellowship (ALTF 277-2014). SF received a senior clinical research fellowship from the Research Foundation Flanders (1802154N). The project was also partially funded by the Antwerp University (GOA 2018, ID36572)., ANR-16-RHUS-0006,PreciNASH,PreciNASH(2016), ANR-20-CE14-0034,DeCodeNASH,L'activation métabolique des cellules dendritiques dans la steatopathie métabolique(2020), European Project: 101042759,Horizon Europe,ERC-2021-STG,Metabo3DC(2022), European Project: 305707,EC:FP7:HEALTH,FP7-HEALTH-2012-INNOVATION-1,RESOLVE(2013)

المصدر: ISSN: 0026-0495.

مصطلحات موضوعية: PPARα, MASLD, MASH, Liver, NAFLD = Non-alcoholic fatty liver disease, NASH, Metabolism, Lipid metabolism, Nuclear receptor, PPAR ALPHA, FAT10, UBD, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology

Relation: info:eu-repo/grantAgreement//101042759/EU/Understanding Metabolic Activation of Dendritic Cells in Non-Alcoholic Fatty Liver Disease/Metabo3DC; info:eu-repo/grantAgreement/EC/FP7/305707/EU/A systems biology approach to RESOLVE the molecular pathology of two hallmarks of patients with metabolic syndrome and its co-morbidities; hypertriglyceridemia and low HDL-cholesterol/RESOLVE

الاتاحة: https://hal.science/hal-04362961
https://hal.science/hal-04362961v1/document
https://hal.science/hal-04362961v1/file/The%20ubiquitin-like%20modifier%20FAT10%20is%20induced%20in%20MASLD%20and%20impairs%20the%20lipid%20regulatory%20activity%20of%20PPARa.pdf
https://doi.org/10.1016/j.metabol.2023.155720

المؤلفون: Deprince, Audrey, Hennuyer, Nathalie, Kooijman, Sander, Pronk, Amanda C M, Baugé, Eric, Lienard, Viktor, Verrijken, An, Dirinck, Eveline, Vonghia, Luisa, Woitrain, Eloïse, Kloosterhuis, Niels J, Marez, Eléonore, Jacquemain, Pauline, Wolters, Justina C, Lalloyer, Fanny, Eberlé, Delphine, Quemener, Sandrine, Vallez, Emmanuelle, Tailleux, Anne, Kouach, Mostafa, Goossens, Jean-Francois, Raverdy, Violeta, Derudas, Bruno, Kuivenhoven, Jan Albert, Croyal, Mikaël, van de Sluis, Bart, Francque, Sven, Pattou, François, Rensen, Patrick C N, Staels, Bart, Haas, Joel T

المصدر: Deprince , A , Hennuyer , N , Kooijman , S , Pronk , A C M , Baugé , E , Lienard , V , Verrijken , A , Dirinck , E , Vonghia , L , Woitrain , E , Kloosterhuis , N J , Marez , E , Jacquemain , P , Wolters , J C , Lalloyer , F , Eberlé , D , Quemener , S , Vallez , E , Tailleux , A , Kouach , M , Goossens , J-F , Raverdy , V , Derudas , B , Kuivenhoven , J ....

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/ecba4d6b-ab06-4fdd-a907-984fbbbe18b0
https://research.rug.nl/en/publications/ecba4d6b-ab06-4fdd-a907-984fbbbe18b0
https://doi.org/10.1002/hep.32631
https://pure.rug.nl/ws/files/230314298/Hepatology_2022_Deprince_Apolipoprotein_F_is_reduced_in_humans_with_steatosis_and_controls_plasma_triglyceride_rich.pdf

المؤلفون: Van Dijck, Evelien, Diels, Sara, Fransen, Erik, Cremers, Tycho Canter, Verrijken, An, Dirinck, Eveline, Hoischen, Alexander, Vandeweyer, Geert, Vanden Berghe, Wim, Van Gaal, Luc, Francque, Sven, Van Hul, Wim

المصدر: Antioxidants; Sep2024, Vol. 13 Issue 9, p1051, 16p

مصطلحات موضوعية: HEPATIC fibrosis, METABOLIC disorders, MOLECULAR probes, GENE families, LIVER diseases

المؤلفون: Zanoni, Paolo, Panteloglou, Grigorios, Othman, Alaa, Haas, Joël T., Meier, Roger, Rimbert, Antoine, Futema, Marta, Khalil, Yara Abou, Norrelykke, Simon Flyvbjerg, Rzepiela, Andrzej Jerzy, Stoma, Szymon, Stebler, Michael, van Dijk, Freerk, Wijers, Melinde, Wolters, Justina Clarinda, Dalila, Nawar, Huijkman, Nicolette C.A., Smit, Marieke, Gallo, Antonio, Carreau, Valérie, Philippi, Anne, Rabès, Jean Pierre H., Boileau, Cathérine R., Visentin, Michele, Vonghia, Luisa, Weyler, Jonas, Francque, Sven M.A., Verrijken, An, Verhaegen, Ann A., van Gaal, Luc F., van Der Graaf, Adriaan, van Rosmalen, Belle Vivica, Robert, Jérôme, Velagapudi, Srividya, Yalcinkaya, Mustafa, Keel, Michaela, Radosavljevic, Silvija, Geier, Andreas, Tybjaerg-Hansen, Anne, Varret, Mathilde, Rohrer, Lucia, Humphries, Steve E., Staels, Bart, van de Sluis, Bart J.A., Kuivenhoven, Jan Albert, von Eckardstein, Arnold

المساهمون: University hospital of Zurich Zurich, Universität Zürich Zürich = University of Zurich (UZH), Institute for Molecular Systems Biology ETH Zurich (IMSB), Department of Biology ETH Zürich (D-BIOL), Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology Zürich (ETH Zürich)-Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology Zürich (ETH Zürich), Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U 1011 (RNMCD), Institut Pasteur de Lille, Pasteur Network (Réseau International des Instituts Pasteur)-Pasteur Network (Réseau International des Instituts Pasteur)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Scientific Center for Optical and Electron Microscopy (ScopeM), Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology Zürich (ETH Zürich), University of Groningen Groningen, ITX-lab unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX-lab), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), St George's, University of London, Laboratoire de Recherche Vasculaire Translationnelle (LVTS (UMR_S_1148 / U1148)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, AP-HP - Hôpital Bichat - Claude Bernard Paris, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Saint-Joseph de Beyrouth (USJ), University of Copenhagen = Københavns Universitet (UCPH), CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), AP-HP. Université Paris Saclay, UFR Sciences de la santé Simone Veil (UVSQ Santé), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Saclay, Antwerp University Hospital Edegem (UZA), University of Antwerp (UA), University of Amsterdam Amsterdam = Universiteit van Amsterdam (UvA), Columbia University New York, University Hospital of Würzburg, University College of London London (UCL), 603091, ANR-10-LABX-46, 2015T068, CVON2017-2020, AOM06024, 2014/267, Pfizer: 24052829, European Molecular Biology Organization, EMBO: ALTF277-2014, Seventh Framework Programme, FP7, Sixth Framework Programme, FP6: LSHM-CT-2005-018734, Fondation Maladies Rares, FMR, International Atherosclerosis Society, IAS, British Heart Foundation, BHF, European Commission, EC, European Research Council, ERC: 694717, ANR 16-RHUS-0006, Agence Nationale de la Recherche, ANR: ANR-16-RHUS-0007, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, SNF: 310030-185109, 31003A-160126, Fonds De La Recherche Scientifique - FNRS, FNRS, Fonds Wetenschappelijk Onderzoek, FWO: 1802154 N, PG008/08, RG3008, Nederlandse Organisatie voor Wetenschappelijk Onderzoek, NWO: 184.021.007, Universität Zürich, UZH: FK-20-037, We acknowledge the use of data from BIOS-consortium ( http://wiki.bbmri.nl/wiki/BIOS_bios ) which is funded by BBMRI-NL (NWO project 184.021.007). Flow cytometry was performed with equipment of the flow cytometry facility, University of Zurich., This work was conducted as part of the TransCard project of the seventh Framework Program (FP7) granted by the European Commission, to J. Albert Kuivenhoven, A. Tybjaerg-Hansen, and A. von Eckardstein (number 603091) as well as partially the FP7 RESOLVE project (to J.T. Haas, B. Staels, A. Verhaegen, S. Francque, L. Van Gaal, and A. von Eckardstein) and the European Genomic Institute for Diabetes (EGID, ANR-10-LABX-46 to B. Staels). Additional work by A. von Eckardstein’s team was funded by the Swiss National Science Foundation (31003A-160126, 310030-185109) and the Swiss Systems X program (2014/267 Medical Research and Development (MRD) HDL-X). P. Zanoni received funding awards from the Swiss Atherosclerosis Society (Arbeitsgruppe Lipide und Atherosklerose AGLA and the DACH Society for Prevention of Cardiovascular Diseases). G. Panteloglou received funding from the University of Zurich (Forschungskredit, grant no. FK-20-037). J. Albert Kuivenhoven is an Established Investigator from the Dutch Heart Foundation (2015T068). J. Albert Kuivenhoven was also supported by GeniusII (CVON2017-2020). The Laboratory for Vascular Translational Science (L.V.T.S.) team is supported by Fondation Maladies Rares, Programme Hospitalier de Recherche Clinique (PHRC) (AOM06024), and the national project CHOPIN (CHolesterol Personalized Innovation), granted by the Agence Nationale de la Recherche (ANR-16-RHUS-0007). Y. Abou Khalil is supported by a grant from Ministère de l’Education Nationale et de la Technologie (France). J.T. Haas was supported by an EMBO Long Term Fellowship (ALTF277-2014). B. Staels is a recipient of an ERC Advanced Grant (no. 694717). Both are also supported by PreciNASH (ANR 16-RHUS-0006). Research at the Antwerp University Hospital was supported by the European Union: FP6 (HEPADIP Contract LSHM-CT-2005-018734). S. Francque has a senior clinical research fellowship from the Fund for Scientific Research (FWO) Flanders (1802154 N). S.E. Humphries received grants RG3008 and PG008/08 from the British Heart Foundation, and the support of the UCLH NIHR BRC. S.E. Humphries directs the UK Children’s FH Register which has been supported by a grant from Pfizer (24052829) given by the International Atherosclerosis Society., This work was conducted as part of the TransCard project of the seventh Framework Program (FP7) granted by the European Commission, to J. Albert Kuivenhoven, A. Tybjaerg-Hansen, and A. von Eckardstein (number 603091) as well as partially the FP7 RESOLVE project (to J.T. Haas, B. Staels, A. Verhaegen, S. Francque, L. Van Gaal, and A. von Eckardstein) and the European Genomic Institute for Diabetes (EGID, ANR-10-LABX-46 to B. Staels). Additional work by A. von Eckardstein's team was funded by the Swiss National Science Foundation (31003A-160126, 310030-185109) and the Swiss Systems X program (2014/267 Medical Research and Development (MRD) HDL-X). P. Zanoni received funding awards from the Swiss Atherosclerosis Society (Arbeitsgruppe Lipide und Atherosklerose AGLA and the DACH Society for Prevention of Cardiovascular Diseases). G. Panteloglou received funding from the University of Zurich (Forschungskredit, grant no. FK-20-037). J. Albert Kuivenhoven is an Established Investigator from the Dutch Heart Foundation (2015T068). J. Albert Kuivenhoven was also supported by GeniusII (CVON2017-2020). The Laboratory for Vascular Translational Science (L.V.T.S.) team is supported by Fondation Maladies Rares, Programme Hospitalier de Recherche Clinique (PHRC) (AOM06024), and the national project CHOPIN (CHolesterol Personalized Innovation), granted by the Agence Nationale de la Recherche (ANR-16-RHUS-0007). Y. Abou Khalil is supported by a grant from Minist?re de l'Education Nationale et de la Technologie (France). J.T. Haas was supported by an EMBO Long Term Fellowship (ALTF277-2014). B. Staels is a recipient of an ERC Advanced Grant (no. 694717). Both are also supported by PreciNASH (ANR 16-RHUS-0006). Research at the Antwerp University Hospital was supported by the European Union: FP6 (HEPADIP Contract LSHMCT- 2005-018734). S. Francque has a senior clinical research fellowship from the Fund for Scientific Research (FWO) Flanders (1802154 N). S.E. Humphries received grants RG3008 and PG008/08 from the British Heart Foundation, and the support of the UCLH NIHR BRC. S.E. Humphries directs the UK Children's FH Register which has been supported by a grant from Pfizer (24052829) given by the International Atherosclerosis Society., ANR-16-RHUS-0006,PreciNASH,PreciNASH(2016), ANR-16-RHUS-0007,CHOPIN,CHOPIN(2016)

المصدر: ISSN: 0009-7330.

مصطلحات موضوعية: Cardiovascular diseases, Endocytosis, Hepatocytes, Hypercholesterolemia, Spliceosomes, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system

Relation: info:eu-repo/semantics/altIdentifier/pmid/34809444; PUBMED: 34809444

الاتاحة: https://hal.science/hal-03554168
https://hal.science/hal-03554168v1/document
https://hal.science/hal-03554168v1/file/Zanoni%20Panteloglou%20CIrc%20Res%202022%20final%20manuscript%20.pdf
https://doi.org/10.1161/CIRCRESAHA.120.318141

المؤلفون: Van Dijck, Evelien, Beckers, Sigri, Diels, Sara, Huybrechts, Tammy, Verrijken, An, van Hoorenbeeck, Kim, Verhulst, Stijn, Massa, Guy, Van Gaal, Luc, Van Hul, Wim

المصدر: 2073-4425 ; Genes

مصطلحات موضوعية: Biology, Human medicine

Relation: info:eu-repo/semantics/altIdentifier/isi/000873407600001

الاتاحة: https://hdl.handle.net/10067/1917150151162165141
https://repository.uantwerpen.be/docstore/d:irua:14719

المؤلفون: Zanoni, P, Panteloglou, G, Othman, A, Haas, JT, Meier, R, Rimbert, A, Futema, M, Abou-Khalil, Y, Nørrelykke, SF, Rzepiela, A, Stoma, S, Stebler, M, Dijk, FV, Wijers, M, Wolters, JC, Dalila, N, Huijkman, N, Smit, M, Gallo, A, Carreau, V, Philippi, A, Rabès, J-P, Boileau, C, Visentin, M, Vonghia, L, Weyler, J, Francque, S, Verrijken, A, Verhaegen, A, Van Gaal, LF, van der Graaf, A, van Rosmalen, BV, Robert, J, Velagapudi, S, Yalcinkaya, M, Keel, M, Radosavljevic, S, Geier, A, Tybjærg-Hansen, A, Varret, M, Rohrer, L, Humphries, SE, Staels, B, van de Sluis, B, Kuivenhoven, JA, Von Eckardstein, A

المصدر: Circulation Research , 130 (1) pp. 80-95. (2022)

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10142022/1/Zanoni%20et%20al%20CIRCRES2020_318141R%20main%20text%20and%20figures.pdf; https://discovery.ucl.ac.uk/id/eprint/10142022/7/Zanoni%20et%20al%20online%20supplement%20CIRCRES2020_318141R.pdf; https://discovery.ucl.ac.uk/id/eprint/10142022/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10142022/1/Zanoni%20et%20al%20CIRCRES2020_318141R%20main%20text%20and%20figures.pdf
https://discovery.ucl.ac.uk/id/eprint/10142022/7/Zanoni%20et%20al%20online%20supplement%20CIRCRES2020_318141R.pdf
https://discovery.ucl.ac.uk/id/eprint/10142022/

المؤلفون: Evelien Van Dijck, Sigri Beckers, Sara Diels, Tammy Huybrechts, An Verrijken, Kim Van Hoorenbeeck, Stijn Verhulst, Guy Massa, Luc Van Gaal, Wim Van Hul

المصدر: Genes; Volume 13; Issue 10; Pages: 1746

مصطلحات موضوعية: proprotein convertase subtilisin/kexin type 1 ( PCSK1 ), rare variants, founder mutation, obesity, overweight

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Human Genomics and Genetic Diseases; https://dx.doi.org/10.3390/genes13101746

الاتاحة: https://doi.org/10.3390/genes13101746