المؤلفون: Zoltowska, Katarzyna, Das, Utpal, Lismont, Sam, Enzlein, Thomas, Maesako, Masato, Houser, Mei, Franco, Maria, Özcan, Burcu, Gomes Moreira, Diana, Karachentsev, Dmitry, Becker, Ann, Hopf, Carsten, Vilar, Marçal, Berezovska, Oksana, Mobley, William, Chávez-Gutiérrez, Lucía

مصطلحات موضوعية: Alzheimers disease, amyloid beta, amyloid toxicity, biochemistry, chemical biology, gamma-secretase, gamma-secretase inhibition, human, mouse, neuroscience, presenilin, rat, Amyloid Precursor Protein Secretases, Amyloid beta-Peptides, Humans, Alzheimer Disease, Signal Transduction, Animals, Neurons, Mice, Feedback, Physiological, Peptide Fragments, Cell Line

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3494t9df
https://escholarship.org/content/qt3494t9df/qt3494t9df.pdf

المؤلفون: Katarzyna Marta Zoltowska, Utpal Das, Sam Lismont, Thomas Enzlein, Masato Maesako, Mei CQ Houser, Maria Luisa Franco, Burcu Özcan, Diana Gomes Moreira, Dmitry Karachentsev, Ann Becker, Carsten Hopf, Marçal Vilar, Oksana Berezovska, William Mobley, Lucía Chávez-Gutiérrez

المصدر: eLife, Vol 12 (2024)

مصطلحات موضوعية: Alzheimer's disease, gamma-secretase, presenilin, amyloid beta, amyloid toxicity, gamma-secretase inhibition, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/90690; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/2631ca395939430b962c9f2eb0249faf

المؤلفون: Dillon J. Rinauro, Fabrizio Chiti, Michele Vendruscolo, Ryan Limbocker

المصدر: Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-32 (2024)

مصطلحات موضوعية: Aggregation kinetics, Secondary nucleation, Protofibrils, Lecanemab, Cellular interactions, Amyloid toxicity, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1750-1326

URL الوصول: https://doaj.org/article/fc5801f1b98b49f29a52e09a1075880f

المؤلفون: Rani Cathrine Chellappa, Palaniswamy Rani

المصدر: Frontiers in Bioscience-Elite, Vol 12, Iss 1, Pp 150-161 (2020)

مصطلحات موضوعية: amyloid toxicity, oxidative stress, rage, srage, polymorphism, ad, Environmental sciences, GE1-350, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.imrpress.com/journal/FBE/12/1/10.2741/E864; https://doaj.org/toc/1945-0494

URL الوصول: https://doaj.org/article/1dd577fbccbc4bff85a14ec0a0ca5b73

المؤلفون: Esteve, Daniel, Molina-Navarro, María Micaela, Giraldo-Reboloso, Esther, Martínez-Varea, Noelia, Blanco-Gandia, Mari Carmen, Rodríguez-Arias, Marta, García-Verdugo, Jose Manuel, Viña, José, Lloret, Ana

المساهمون: Universitat Politècnica de València. Escuela Técnica Superior de Ingeniería Agronómica y del Medio Natural - Escola Tècnica Superior d'Enginyeria Agronòmica i del Medi Natural, European Commission, Generalitat Valenciana, Universitat de València, Instituto de Salud Carlos III, Agencia Estatal de Investigación, European Regional Development Fund

مصطلحات موضوعية: Subventricular zone, Beta-amyloid toxicity, Neurogenesis, Senescence, Olfaction, BIOLOGIA CELULAR

Relation: Molecular Neurobiology; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-110906RB-I00/ES/NUEVAS INTERVENCIONES TERAPEUTICAS MULTIDOMINIO PARA RETRASAR LA FRAGILIDAD Y LA DISCAPACIDAD. IDENTIFICACION DE MECANISMOS MOLECULARES CON RELEVANCIA TRASLACIONAL/; info:eu-repo/grantAgreement/GVA//PROMETEO%2F2019%2F097/; info:eu-repo/grantAgreement/EC/H2020/696295/EU; info:eu-repo/grantAgreement/ISCIII//CB16%2F10%2F00435//CIBER-FES/; info:eu-repo/grantAgreement/EC/H2020/825546/EU; info:eu-repo/grantAgreement/UV//UV-INV-AE-1546096/; https://doi.org/10.1007/s12035-021-02620-6; urn:issn:0893-7648; http://hdl.handle.net/10251/195605; PMC8857127

الاتاحة: http://hdl.handle.net/10251/195605
https://doi.org/10.1007/s12035-021-02620-6

المؤلفون: Davani L., Fu X., De Simone A., Li P., Montanari S., Lammerhofer M., Andrisano V.

المساهمون: Davani L., Fu X., De Simone A., Li P., Montanari S., Lammerhofer M., Andrisano V.

مصطلحات موضوعية: Alzheimer's disease, Amyloid toxicity, Biomarker, Lipid, Mass spectrometry

وصف الملف: ELETTRONICO

Relation: info:eu-repo/semantics/altIdentifier/pmid/35749963; info:eu-repo/semantics/altIdentifier/wos/WOS:000861996600010; volume:219; firstpage:1; lastpage:9; numberofpages:9; journal:JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS; https://hdl.handle.net/11585/902600; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85132715683; https://www.sciencedirect.com/science/article/pii/S0731708522002977?via=ihub

الاتاحة: https://hdl.handle.net/11585/902600
https://doi.org/10.1016/j.jpba.2022.114876
https://www.sciencedirect.com/science/article/pii/S0731708522002977?via=ihub

المؤلفون: Richard E. Dolder, Jyotsna Kumar, Michael Reidy, Daniel C. Masison

المصدر: Biology; Volume 11; Issue 12; Pages: 1846

مصطلحات موضوعية: DnaJB6, J-domain proteins, amyloid, amyloid toxicity, yeast prions

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Biotechnology; https://dx.doi.org/10.3390/biology11121846

الاتاحة: https://doi.org/10.3390/biology11121846

المؤلفون: Prashant Bharadwaj, Ralph Martins

المصدر: Neural Regeneration Research, Vol 15, Iss 10, Pp 1931-1936 (2020)

مصطلحات موضوعية: alzheimer’s disease, amyloid toxicity, autophagy, aβ42 oligomer, high-throughput screening, latrepirdine, neuroprotection, yeast model, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=10;spage=1931;epage=1936;aulast=; https://doaj.org/toc/1673-5374

URL الوصول: https://doaj.org/article/14b927896b484abfb618dfa068620794

المؤلفون: Rinauro, Dillon J, Chiti, Fabrizio, Vendruscolo, Michele, Limbocker, Ryan

مصطلحات موضوعية: Aggregation kinetics, Amyloid toxicity, Biophysics, Cellular interactions, Diagnostics, Drug discovery, Fibril fragmentation, Lecanemab, Protofibrils, Secondary nucleation, Therapeutics, Humans, Amyloid, Parkinson Disease, Proteostasis Deficiencies, Amyloid beta-Peptides

وصف الملف: application/pdf; text/xml

Relation: https://www.repository.cam.ac.uk/handle/1810/364879

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/364879

المؤلفون: Chacon, Marcelo A., Varela Nallar, Lorena, Inestrosa, Nibaldo C.

مصطلحات موضوعية: SOLUBLE-PROTEIN OLIGOMERS, SIGNALING PATHWAY, PEPTIDE NEUROTOXICITY, INHIBITS APOPTOSIS, ALZHEIMERS-DISEASE, AMYLOID TOXICITY, SPATIAL MEMORY, HIPPOCAMPAL, CATENIN, ACTIVATION, 03 Good Health and Well-being, 03 Salud y bienestar

وصف الملف: 13 páginas

Relation: MEDLINE:18521822; https://doi.org/10.1002/jcp.21497; https://repositorio.uc.cl/handle/11534/76035; WOS:000258899900023

الاتاحة: https://repositorio.uc.cl/handle/11534/76035
https://doi.org/10.1002/jcp.21497

المؤلفون: Saifullah Abubakar, Boon-Keat Khor, Kooi-Yeong Khaw, Vikneswaran Murugaiyah, Kit-Lam Chan

المصدر: Phytomedicine Plus, Vol 1, Iss 1, Pp 100022- (2021)

مصطلحات موضوعية: Dillenia suffruticosa, Triterpenoids, Flavonoids, Cholinesterase inhibition, Molecular docking, Protective β-amyloid toxicity, Other systems of medicine, RZ201-999

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S266703132100004X; https://doaj.org/toc/2667-0313

URL الوصول: https://doaj.org/article/74478e9c522442f7adb958128a24cf3f

المؤلفون: Canet, Geoffrey, Zussy, Charleine, Hernandez, Célia, Chevallier, Nathalie, Marchi, Nicola, Desrumaux, Catherine, Givalois, Laurent

المساهمون: Mécanismes moléculaires dans les démences neurodégénératives (MMDN), Université Montpellier 2 - Sciences et Techniques (UM2)-École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut de Génomique Fonctionnelle (IGF), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Université Laval Québec (ULaval), ANR-11-LABX-0021,Lipstic,Lipoprotéines et santé : prévention et traitement des maladies inflammatoires non vasculaires et du cancer(2011)

المصدر: ISSN: 0028-3835.

مصطلحات موضوعية: Alzheimer’s disease, Amyloid toxicity, Chronic glucocorticoids consumption, Memory deficits, Neuroinflammation, Alzheimer's disease, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology

الاتاحة: https://hal.science/hal-03870294
https://hal.science/hal-03870294v1/document
https://hal.science/hal-03870294v1/file/GIvalois%20Neuroendoc%202022.pdf
https://doi.org/10.1159/000521559

المؤلفون: Marija Iljina, Liu Hong, Mathew H. Horrocks, Marthe H. Ludtmann, Minee L. Choi, Craig D. Hughes, Francesco S. Ruggeri, Tim Guilliams, Alexander K. Buell, Ji-Eun Lee, Sonia Gandhi, Steven F. Lee, Clare E. Bryant, Michele Vendruscolo, Tuomas P. J. Knowles, Christopher M. Dobson, Erwin De Genst, David Klenerman

المصدر: BMC Biology, Vol 15, Iss 1, Pp 1-14 (2017)

مصطلحات موضوعية: Protein aggregation, Amyloid toxicity, Neurodegeneration, Aggregation inhibitors, Antibody, Single-molecule fluorescence, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12915-017-0390-6; https://doaj.org/toc/1741-7007

URL الوصول: https://doaj.org/article/663675b7591d4941be32bb03ca0a9083

المؤلفون: Shi, Liu, Winchester, Laura M., Liu, Benjamine Y., Killick, Richard, Ribe, Elena M., Westwood, Sarah, Baird, Alison L., Buckley, Noel J., Hong, Shengjun, Dobricic, Valerija, Kilpert, Fabian, Franke, Andre, Kiddle, Steven, Sattlecker, Martina, Dobson, Richard, Cuadrado, Antonio, Hye, Abdul, Ashton, Nicholas J., Morgan, Angharad R., Bos, Isabelle, Vos, Stephanie J. B., ten Kate, Mara, Scheltens, Philip, Vandenberghe, Rik, Gabel, Silvy, Meersmans, Karen, Engelborghs, Sebastiaan, De Roeck, Ellen E., Sleegers, Kristel, Frisoni, Giovanni B., Blin, Olivier, Richardson, Jill C., Bordet, Regis, Molinuevo, Jose L., Rami, Lorena, Wallin, Anders, Kettunen, Petronella, Tsolaki, Magda, Verhey, Frans, Lleo, Alberto, Alcolea, Daniel, Popp, Julius, Peyratout, Gwendoline, Martinez-Lage, Pablo, Tainta, Mikel, Johannsen, Peter, Teunissen, Charlotte E., Freund-Levi, Yvonne, Frolich, Lutz, Legido-Quigley, Cristina, Barkhof, Frederik, Blennow, Kaj, Rasmussen, Katrine Laura, Nordestgaard, Borge Gronne, Frikke-Schmidt, Ruth, Nielsen, Sune Fallgaard, Soininen, Hilkka, Vellas, Bruno, Kloszewska, Iwona, Mecocci, Patrizia, Zetterberg, Henrik, Morgan, B. Paul, Streffer, Johannes, Visser, Pieter Jelle, Bertram, Lars, Nevado-Holgado, Alejo J., Lovestone, Simon

المصدر: Shi , L , Winchester , L M , Liu , B Y , Killick , R , Ribe , E M , Westwood , S , Baird , A L , Buckley , N J , Hong , S , Dobricic , V , Kilpert , F , Franke , A , Kiddle , S , Sattlecker , M , Dobson , R , Cuadrado , A , Hye , A , Ashton , N J , Morgan , A R , Bos , I , Vos , S J B , ten Kate , M , Scheltens ....

مصطلحات موضوعية: ATN framework, Dickkopf-1, replication, SomaScan, Wnt signaling, BETA-AMYLOID TOXICITY, MENDELIAN RANDOMIZATION, NEURODEGENERATION, DEGENERATION, PATHOGENESIS, METAANALYSIS, ACTIVATION, INDUCTION, PATHWAY, MODELS

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/58e1f81e-d02f-41bf-9758-1eb28b2f91c5
https://doi.org/10.3233/JAD-200208

المؤلفون: Ivana Sirangelo, Margherita Borriello, Silvia Vilasi, Clara Iannuzzi

المصدر: International Journal of Molecular Sciences; Volume 21; Issue 13; Pages: 4636

مصطلحات موضوعية: amyloid aggregation, human insulin, hydroxytyrosol, amyloid toxicity

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Neurobiology; https://dx.doi.org/10.3390/ijms21134636

الاتاحة: https://doi.org/10.3390/ijms21134636

المؤلفون: Ramesh, M., Acharya, A., Murugan, N. A., Ila, H., Govindaraju, T.

المصدر: ChemBioChem. 22(23):3348-3357

مصطلحات موضوعية: Alzheimer's disease, amyloid beta, amyloid toxicity modulator, Tau protein, thiophene compounds, amyloid beta protein, neuroprotective agent, protein aggregate, thiophene derivative, Alzheimer disease, cell line, chemistry, drug effect, human, metabolism, molecular library, pharmacology, preclinical study, Amyloid beta-Peptides, Drug Evaluation, Preclinical, Humans, Neuroprotective Agents, Protein Aggregates, Small Molecule Libraries, tau Proteins, Thiophenes

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-312041

المؤلفون: Clara Iannuzzi, Gaetano Irace, Ivana Sirangelo

المصدر: Molecules, Vol 20, Iss 2, Pp 2510-2528 (2015)

مصطلحات موضوعية: glycosaminoglycans, amyloid aggregation, amyloid toxicity inhibition, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1420-3049/20/2/2510; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/8fe42d91bca5422a8e7c111ef264302c

المؤلفون: Annalisa Relini, Nadia Marano, Alessandra Gliozzi

المصدر: Biomolecules, Vol 4, Iss 1, Pp 20-55 (2013)

مصطلحات موضوعية: amyloidogenic proteins, misfolding, amyloid aggregation, fibrillogenesis, membrane permeabilization, amyloid toxicity, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: http://www.mdpi.com/2218-273X/4/1/20; https://doaj.org/toc/2218-273X

URL الوصول: https://doaj.org/article/78205930d0534a349b4149ecf4505aaf

المؤلفون: Klenerman, D, Iljina, M, Hong, L, Horrocks, Mathew, Ludtmann, MH, Choi, ML, Hughes, Craig, Ruggeri, Francesco, Guilliams, T, Buell, AK, Lee, Ji-Eun, Gandhi, S, Lee, Steven, Bryant, Clare, Vendruscolo, Michele, Knowles, Tuomas, Dobson, Christopher, De Genst, E, Klenerman, David

مصطلحات موضوعية: protein aggregation, amyloid toxicity, neurodegeneration, aggregation inhibitors, antibody, single-molecule fluorescence

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

Relation: https://www.repository.cam.ac.uk/handle/1810/264943

الاتاحة: https://doi.org/10.17863/CAM.10303
https://www.repository.cam.ac.uk/handle/1810/264943

المؤلفون: Iljina, M, Hong, L, Horrocks, MH, Ludtmann, MH, Choi, ML, Hughes, CD, Ruggeri, FS, Guilliams, T, Buell, AK, Lee, J-E, Gandhi, S, Lee, SF, Bryant, CE, Vendruscolo, M, Knowles, TPJ, Dobson, CM, De Genst, E, Klenerman, D

المصدر: BMC Biology , 15 , Article 57. (2017)

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Biology, Life Sciences & Biomedicine - Other Topics, Protein aggregation, Amyloid toxicity, Neurodegeneration, Aggregation inhibitors, Antibody, Single-molecule fluorescence, SPORADIC PARKINSONS-DISEASE, MULTIPLE SYSTEM ATROPHY, ANTIBODY FRAGMENTS, LEWY BODIES, AGGREGATION, PATHOLOGY, BRAIN, IMMUNOREACTIVITY

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/1565307/1/s12915-017-0390-6.pdf; https://discovery.ucl.ac.uk/id/eprint/1565307/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/1565307/1/s12915-017-0390-6.pdf
https://discovery.ucl.ac.uk/id/eprint/1565307/