يعرض 1 - 11 نتائج من 11 نتيجة بحث عن '"Ammirati, Mark J."', وقت الاستعلام: 0.37s تنقيح النتائج
  1. 1
    Academic Journal
    Insights into Mechanism of Glucokinase Activation

    المؤلفون: Liu, Shenping, Ammirati, Mark J., Song, Xi, Knafels, John D., Zhang, Jeff, Greasley, Samantha E., Pfefferkorn, Jeffrey A., Qiu, Xiayang

    المصدر: Journal of Biological Chemistry ; volume 287, issue 17, page 13598-13610 ; ISSN 0021-9258

    الاتاحة: http://dx.doi.org/10.1074/jbc.m111.274126
    https://api.elsevier.com/content/article/PII:S0021925820529335?httpAccept=text/xml
    https://api.elsevier.com/content/article/PII:S0021925820529335?httpAccept=text/plain
    https://syndication.highwire.org/content/doi/10.1074/jbc.M111.274126

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  2. 2
    Academic Journal
    The 2.0 Å crystal structure of the ERα ligand‐binding domain complexed with lasofoxifene

    المؤلفون: Vajdos, Felix F., Hoth, Lise R., Geoghegan, Kieran F., Simons, Samuel P., LeMotte, Peter K., Danley, Dennis E., Ammirati, Mark J., Pandit, Jayvardhan

    المصدر: Protein Science ; volume 16, issue 5, page 897-905 ; ISSN 0961-8368 1469-896X

    الاتاحة: https://doi.org/10.1110/ps.062729207
    https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1110%2Fps.062729207
    https://onlinelibrary.wiley.com/doi/pdf/10.1110/ps.062729207

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  3. 3
    Academic Journal
    (3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrrolidin-2-yl]-methanone: A potent, selective, orally active dipeptidyl peptidase IV inhibitor

    المؤلفون: Ammirati, Mark J., Andrews, Kim M., Boyer, David D., Brodeur, Anne M., Danley, Dennis E., Doran, Shawn D., Hulin, Bernard, Liu, Shenping, McPherson, R. Kirk, Orena, Stephen J., Parker, Janice C., Polivkova, Jana, Qiu, Xiayang, Soglia, Carolyn B., Treadway, Judith L., VanVolkenburg, Maria A., Wilder, Donald C., Piotrowski, David W.

    المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 19, issue 7, page 1991-1995 ; ISSN 0960-894X

    الاتاحة: http://dx.doi.org/10.1016/j.bmcl.2009.02.041
    https://api.elsevier.com/content/article/PII:S0960894X09001966?httpAccept=text/xml
    https://api.elsevier.com/content/article/PII:S0960894X09001966?httpAccept=text/plain

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  4. 4
    Academic Journal
    Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules

    المؤلفون: Qiu, Xiayang, Mistry, Anil, Ammirati, Mark J, Chrunyk, Boris A, Clark, Ronald W, Cong, Yang, Culp, Jeffrey S, Danley, Dennis E, Freeman, Thomas B, Geoghegan, Kieran F, Griffor, Matthew C, Hawrylik, Steven J, Hayward, Cheryl M, Hensley, Preston, Hoth, Lise R, Karam, George A, Lira, Maruja E, Lloyd, David B, McGrath, Katherine M, Stutzman-Engwall, Kim J, Subashi, Ann K, Subashi, Timothy A, Thompson, John F, Wang, Ing-Kae, Zhao, Honglei, Seddon, Andrew P

    المصدر: Nature Structural & Molecular Biology ; volume 14, issue 2, page 106-113 ; ISSN 1545-9993 1545-9985

    الاتاحة: http://dx.doi.org/10.1038/nsmb1197
    http://www.nature.com/articles/nsmb1197.pdf
    http://www.nature.com/articles/nsmb1197

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  5. 5
    Academic Journal
    Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia

    المؤلفون: Cunningham, David, Danley, Dennis E, Geoghegan, Kieran F, Griffor, Matthew C, Hawkins, Julie L, Subashi, Timothy A, Varghese, Alison H, Ammirati, Mark J, Culp, Jeffrey S, Hoth, Lise R, Mansour, Mahmoud N, McGrath, Katherine M, Seddon, Andrew P, Shenolikar, Shirish, Stutzman-Engwall, Kim J, Warren, Laurie C, Xia, Donghui, Qiu, Xiayang

    المصدر: Nature Structural & Molecular Biology ; volume 14, issue 5, page 413-419 ; ISSN 1545-9993 1545-9985

    الاتاحة: http://dx.doi.org/10.1038/nsmb1235
    http://www.nature.com/articles/nsmb1235.pdf
    http://www.nature.com/articles/nsmb1235

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  6. 6
    Academic Journal
    cis-2,5-Dicyanopyrrolidine Inhibitors of Dipeptidyl Peptidase IV: Synthesis and in Vitro, in Vivo, and X-ray Crystallographic Characterization

    المؤلفون: Wright, Stephen W., Ammirati, Mark J., Andrews, Kim M., Brodeur, Anne M., Danley, Dennis E., Doran, Shawn D., Lillquist, Jay S., McClure, Lester D., McPherson, R. Kirk, Orena, Stephen J., Parker, Janice C., Polivkova, Jana, Qiu, Xiayang, Soeller, Walter C., Soglia, Carolyn B., Treadway, Judith L., VanVolkenburg, Maria A., Wang, Hong, Wilder, Donald C., Olson, Thanh V.

    المصدر: Journal of Medicinal Chemistry ; volume 49, issue 11, page 3068-3076 ; ISSN 0022-2623 1520-4804

    الاتاحة: http://dx.doi.org/10.1021/jm0600085
    https://pubs.acs.org/doi/pdf/10.1021/jm0600085

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  7. 7
    Academic Journal
    Discovery of a novel series of 6-azauracil-based thyroid hormone receptor ligands: potent, TRβ subtype-selective thyromimetics

    المؤلفون: Dow, Robert L., Schneider, Steven R., Paight, Ernest S., Hank, Richard F., Chiang, Phoebe, Cornelius, Peter, Lee, Eunsun, Newsome, William P., Swick, Andrew G., Spitzer, Josephine, Hargrove, Diane M., Patterson, Terrell A., Pandit, Jayvardhan, Chrunyk, Boris A., LeMotte, Peter K., Danley, Dennis E., Rosner, Michele H., Ammirati, Mark J., Simons, Samuel P., Schulte, Gayle K., Tate, Bonnie F., DaSilva-Jardine, Paul

    المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 13, issue 3, page 379-382 ; ISSN 0960-894X

    الاتاحة: http://dx.doi.org/10.1016/s0960-894x(02)00947-2
    https://api.elsevier.com/content/article/PII:S0960894X02009472?httpAccept=text/xml
    https://api.elsevier.com/content/article/PII:S0960894X02009472?httpAccept=text/plain

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  8. 8
    Academic Journal
    Insights into Mechanism of Glucokinase Activation.

    المؤلفون: Shenping Liu1 shenping.liu@pfizer.com, Ammirati, Mark J.1, Xi Song1, Knafels, John D.1, Jeff Zhang1, Greasley, Samantha E.2, Pfefferkorn, Jeffrey A.3, Xiayang Qiu1

    المصدر: Journal of Biological Chemistry. 4/20/2012, Vol. 287 Issue 17, p13598-13610. 13p.

    مصطلحات موضوعية: *GLUCOKINASE, *HUMAN experimentation, *BLOOD plasma, *GENETIC mutation, *HYPOGLYCEMIA, *INSULIN, *CLINICAL trials, *X-ray scattering

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  9. 9
    Academic Journal
    (3R,4S)-4-(2,4,5-Trifluorophenyl)-pyrrolidin-3-ylamine inhibitors of dipeptidyl peptidase IV: Synthesis, in vitro, in vivo, and X-ray crystallographic characterization

    المؤلفون: Wright, Stephen W. stephen.w.wright@pfizer.com, Ammirati, Mark J.1, Andrews, Kim M.1, Brodeur, Anne M.1, Danley, Dennis E.1, Doran, Shawn D.1, Lillquist, Jay S.1, Liu, Shenping1, McClure, Lester D.1, McPherson, R. Kirk1, Olson, Thanh V.1, Orena, Stephen J.1, Parker, Janice C.1, Rocke, Benjamin N.1, Soeller, Walter C.1, Soglia, Carolyn B.1, Treadway, Judith L.1, VanVolkenburg, Maria A.1, Zhao, Zhengrong1, Cox, Eric D.1

    المصدر: Bioorganic & Medicinal Chemistry Letters. Oct2007, Vol. 17 Issue 20, p5638-5642. 5p.

    مصطلحات موضوعية: *PROTEOLYTIC enzymes, *ENDOCRINE diseases, *CARBOHYDRATE intolerance, *PYRROLIDINE


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  10. 10
    Academic Journal
    Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules.

    المؤلفون: Xiayang Qiu, Mistry, Anil, Ammirati, Mark J., Chrunyk, Boris A., Clark, Ronald W., Yang Cong, Culp, Jeffrey S., Danley, Dennis E., Freeman, Thomas B., Geoghegan, Kieran F., Griffor, Matthew C., Hawrylik, Steven J., Hayward, Cheryl M., Hensley, Preston, Hoth, Lise R., Karam, George A., Lira, Maruja E., Lloyd, David B., McGrath, Katherine M., Stutzman-Engwall, Kim J.

    المصدر: Nature Structural & Molecular Biology; Feb2007, Vol. 14 Issue 2, p106-113, 8p, 1 Graph

    مصطلحات موضوعية: GLYCOPROTEINS, HIGH density lipoproteins, BLOOD lipoproteins, CHOLESTEROL, ISOPENTENOIDS, LIPIDS


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  11. 11
    Academic Journal
    Crystallizable HIV-1 protease derived from expression of the viral pol gene in Escherichia coli

    المؤلفون: Danley, Dennis E., Geoghegan, Kieran F., Scheld, Kathryn G., Lee, S.Edward, Merson, James R., Hawrylik, Steven J., Rickett, Graham A., Ammirati, Mark J., Hobart, Peter M.

    المصدر: Biochemical and Biophysical Research Communications ; volume 165, issue 3, page 1043-1050 ; ISSN 0006-291X

    الاتاحة: http://dx.doi.org/10.1016/0006-291x(89)92707-1
    https://api.elsevier.com/content/article/PII:0006291X89927071?httpAccept=text/xml
    https://api.elsevier.com/content/article/PII:0006291X89927071?httpAccept=text/plain

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