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1Academic Journal
المؤلفون: Raoudha Zouari-Kessentini, Najet Srairi-Abid, Amine Bazaa, Mohamed El Ayeb, Jose Luis, Naziha Marrakchi
المصدر: BioMed Research International, Vol 2013 (2013)
مصطلحات موضوعية: Medicine
Relation: http://dx.doi.org/10.1155/2013/391389; https://doaj.org/toc/2314-6133; https://doaj.org/toc/2314-6141; https://doaj.org/article/2b1ae2b4a7104278b5f5b7a3f6148176
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2Academic Journal
المؤلفون: Amine Bazaa, Eddy Pasquier, Céline Defilles, Ines Limam, Raoudha Kessentini-Zouari, Olfa Kallech-Ziri, Assou El Battari, Diane Braguer, Mohamed El Ayeb, Naziha Marrakchi, José Luis
المصدر: PLoS ONE, Vol 5, Iss 4, p e10124 (2010)
وصف الملف: electronic resource
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3Academic Journal
المؤلفون: Olfa, Kallech-Ziri, José, Luis, Salma, Daoud, Amine, Bazaa, Najet, Srairi Abid, Nicolas, Andreotti, Maxime, Lehmann, Raoudha, Zouari, Kamel, Mabrouk, Jacques, Marvaldi, Jean-Marc, Sabatier, Mohamed, El Ayeb, Naziha, Marrakchi
المصدر: Laboratory Investigation ; volume 85, issue 12, page 1507-1516 ; ISSN 0023-6837
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المؤلفون: Cécile V. Denis, Paulette Legendre, Peter J. Lenting, Frédéric Adam, Amine Bazaa, Olivier D. Christophe, Gabriel Aymé, Valérie Proulle
المساهمون: Institut National de la Santé et de la Recherche Médicale (INSERM), AYME, Gabriel
المصدر: Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2017, 37 (9), pp.1736-1740. ⟨10.1161/ATVBAHA.117.309319⟩مصطلحات موضوعية: 0301 basic medicine, Phage display, [SDV.BIO]Life Sciences [q-bio]/Biotechnology, 030204 cardiovascular system & hematology, [SDV.BBM.BM] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, 0302 clinical medicine, Antibody Specificity, hemic and lymphatic diseases, Leukocytes, Platelet, [SDV.BBM.BC] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], Mice, Knockout, biology, Chemistry, Platelet Glycoprotein GPIb-IX Complex, 3. Good health, Cell biology, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM], Chemotaxis, Leukocyte, [SDV.SP.PHARMA] Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, cardiovascular system, [SDV.IMM]Life Sciences [q-bio]/Immunology, [SDV.IMM.IMM] Life Sciences [q-bio]/Immunology/Immunotherapy, Cardiology and Cardiovascular Medicine, circulatory and respiratory physiology, Blood Platelets, congenital, hereditary, and neonatal diseases and abnormalities, [SDV.SP.MED] Life Sciences [q-bio]/Pharmaceutical sciences/Medication, [SDV.IMM] Life Sciences [q-bio]/Immunology, medicine.drug_class, Hemorrhage, Cross Reactions, Monoclonal antibody, [SDV.SP.PG] Life Sciences [q-bio]/Pharmaceutical sciences/Galenic pharmacology, Capillary Permeability, 03 medical and health sciences, Protein Domains, Von Willebrand factor, [SDV.SP.MED]Life Sciences [q-bio]/Pharmaceutical sciences/Medication, In vivo, von Willebrand Factor, medicine, Animals, Humans, Avidity, Inflammation, Dose-Response Relationship, Drug, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, [SDV.IMM.IMM]Life Sciences [q-bio]/Immunology/Immunotherapy, [SDV.BIO] Life Sciences [q-bio]/Biotechnology, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Single-domain antibody, [SDV.SP.PG]Life Sciences [q-bio]/Pharmaceutical sciences/Galenic pharmacology, Immunology, biology.protein, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, Single-Chain Antibodies
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المؤلفون: Peter J. Lenting, Véronique Regnault, Olivier D. Christophe, Cécile V. Denis, Gabriel Aymé, Paulette Legendre, Amélie Harel, Vincent Muczynski, Cécile Loubière, Marc Vasse, Amine Bazaa, Delphine Borgel
المساهمون: Hémostase, Inflammation, Thrombose (HITH - U1176 Inserm - CHU Bicêtre), Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM)-AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Inovarion SAS, Défaillance Cardiovasculaire Aiguë et Chronique (DCAC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Hôpital Foch [Suresnes], Service d'immuno-hématologie pédiatrique [CHU Necker], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), REGNAULT, Véronique, AYME, Gabriel, Institut National de la Santé et de la Recherche Médicale (INSERM)
المصدر: Blood
Blood, American Society of Hematology, 2017, 129 (17), pp.2443-2454. ⟨10.1182/blood-2016-06-724351⟩مصطلحات موضوعية: 0301 basic medicine, [SDV.BIO]Life Sciences [q-bio]/Biotechnology, Vitamin K, [SDV]Life Sciences [q-bio], Gene Expression, MESH: Factor X, Plasma protein binding, [SDV.BBM.BM] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, MESH: Mice, Knockout, Biochemistry, Mice, chemistry.chemical_compound, 0302 clinical medicine, MESH: RNA, Small Interfering, MESH: Animals, MESH: Nerve Tissue Proteins, RNA, Small Interfering, Internalization, Receptor, [SDV.BBM.BC] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], Factor X Deficiency, MESH: Organ Specificity, media_common, Mice, Knockout, MESH: Kinetics, Chemistry, Factor X, Scavenger Receptors, Class A, Hematology, Endocytosis, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM], [SDV] Life Sciences [q-bio], C-Reactive Protein, Organ Specificity, [SDV.SP.PHARMA] Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, MESH: HEK293 Cells, MESH: Endocytosis, [SDV.IMM]Life Sciences [q-bio]/Immunology, [SDV.IMM.IMM] Life Sciences [q-bio]/Immunology/Immunotherapy, Protein Binding, [SDV.SP.MED] Life Sciences [q-bio]/Pharmaceutical sciences/Medication, MESH: Gene Expression, [SDV.IMM] Life Sciences [q-bio]/Immunology, Immunoprecipitation, media_common.quotation_subject, Immunology, Nerve Tissue Proteins, MESH: Anticoagulants, MESH: Factor X Deficiency, [SDV.SP.PG] Life Sciences [q-bio]/Pharmaceutical sciences/Galenic pharmacology, Cell Line, 03 medical and health sciences, [SDV.SP.MED]Life Sciences [q-bio]/Pharmaceutical sciences/Medication, MESH: Mice, Inbred C57BL, MESH: C-Reactive Protein, MESH: Protein Binding, Animals, Humans, Scavenger receptor, MESH: Mice, MESH: Humans, Macrophages, HEK 293 cells, MESH: Macrophages, MESH: Vitamin K, Anticoagulants, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, [SDV.IMM.IMM]Life Sciences [q-bio]/Immunology/Immunotherapy, Cell Biology, Molecular biology, [SDV.BIO] Life Sciences [q-bio]/Biotechnology, MESH: Scavenger Receptors, Class A, MESH: Cell Line, Mice, Inbred C57BL, Kinetics, [SDV.SP.PG]Life Sciences [q-bio]/Pharmaceutical sciences/Galenic pharmacology, HEK293 Cells, 030104 developmental biology, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, 030215 immunology
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المؤلفون: Erwann P. Loret, Olfa Kallech-Ziri, Naziha Marrakchi, Amine Bazaa, Sofiane Bezzine, Najet Srairi-Abid, Aida Karray, José Luis, Raoudha Zouari-Kessentini, Mohamed El Ayeb
المساهمون: Laboratoire des Venins et Toxines, Institut Pasteur de Tunis, Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Centre de Recherches en Oncologie biologique et Oncopharmacologie (CRO2), Aix Marseille Université (AMU)- Hôpital de la Timone [CHU - APHM] (TIMONE)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Supérieur de Biotechnologie de Sfax (ISBS), Université de Sfax - University of Sfax, Faculté de Médecine de Tunis, Université de Tunis El Manar (UTM), This work was supported in part by grants from the CMCU (Comité Mixte de Coopération Universitaire France-Tunisie), the ARC (Association pour la Recherche sur le Cancer) and the Cancéropôle Provence-Alpes-Côte d'Azur., We thank Pr. Hechmi Louzir, head of Institut Pasteur de Tunis for his continuous interest in this study and for his support. Dr Benlasfar Zakaria (Laboratoire Vétérinaire, Institut Pasteur de Tunis) is acknowledged for providing viper venom. We thank Ms Dorra Abdelmalek for her help during the preparation of this work. Authors thank Pr. Youssef Gargouri (Laboratoire de Biochimie et de Génie Enzymatique des Lipases, Sfax, Tunisia) for his fruitful interest to this work. We thank Pr Juan. J. Calvete for mass spectrometry experiment (Instituto de Biomedicina de Valencia, C.S.I.C., Jaume Roig 11, 46010 Valencia, Spain).
المصدر: Toxicon
Toxicon, Elsevier, 2009, 53 (4), pp.444-53. ⟨10.1016/j.toxicon.2009.01.003⟩مصطلحات موضوعية: Blood Platelets, MESH: Cell Line, Tumor, MESH: Phospholipases A2/chemistry, [SDV]Life Sciences [q-bio], Molecular Sequence Data, MESH: Rabbits, Venom, Viper Venoms, MESH: Amino Acid Sequence, Toxicology, 03 medical and health sciences, MESH: Phospholipases A2/pharmacology, MESH: Blood Platelets/drug effects, Phospholipase A2, Cell Movement, Cell Line, Tumor, Cell Adhesion, Viperidae, Animals, Humans, MESH: Blood Coagulation/drug effects, MESH: Animals, Amino Acid Sequence, Blood Coagulation, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, MESH: Humans, MESH: Molecular Sequence Data, biology, 030302 biochemistry & molecular biology, Cerastes cerastes, biology.organism_classification, MESH: Viper Venoms/chemistry, Fibronectin, Phospholipases A2, Enzyme, MESH: Viperidae/physiology, Biochemistry, chemistry, Snake venom, Sephadex, MESH: Cell Movement/drug effects, MESH: Viper Venoms/enzymology, biology.protein, lipids (amino acids, peptides, and proteins), HT1080, Rabbits, MESH: Cell Adhesion/drug effects
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المؤلفون: Naziha Marrakchi, Amine Bazaa, Ali Gargouri, Samah Sarray, Anis Karboul, Mohamed El Ayeb, Jed Jebali, Khemais Benhaj
المساهمون: Laboratoire des Venins et Biomolécules Thérapeutiques - Laboratory of Venoms and Therapeutic Biomolecules (LR11IPT08), Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Laboratoire de Génétique Moléculaire des Eucaryotes, Centre de Biotechnologie de Sfax (CBS), Faculté des Sciences Mathématiques, Physiques et Naturelles de Tunis (FST), Université de Tunis El Manar (UTM), Laboratoire de Microbiologie Moléculaire, Vaccinologie et Développement Biotechnologique (LR11IPT01), Faculté de Médecine de Tunis
المصدر: Toxicon
Toxicon, Elsevier, 2009, 53 (2), pp.228-237. ⟨10.1016/j.toxicon.2008.11.006⟩مصطلحات موضوعية: DNA, Complementary, Protein family, Sequence analysis, [SDV]Life Sciences [q-bio], Molecular Sequence Data, Gene shuffling, Sequence alignment, Toxicology, Genetic diversity, 03 medical and health sciences, Macrovipera lebetina, C-type lectin, Complementary DNA, Crotalid Venoms, Viperidae, Animals, Lectins, C-Type, Amino Acid Sequence, Viper, Cloning, Molecular, Phylogeny, 030304 developmental biology, Serine protease, 0303 health sciences, biology, 030302 biochemistry & molecular biology, Genetic Variation, biology.organism_classification, Molecular biology, 3. Good health, CTL, Gene Expression Regulation, biology.protein, cDNA cloning
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المؤلفون: Cécile Loubière, Amélie Harel, Ghislaine Cherel, Olivier D. Christophe, Amine Bazaa, Peter J. Lenting, Vincent Muczynski, Cécile V. Denis
المصدر: Blood. 127(6)
مصطلحات موضوعية: 0301 basic medicine, Immunology, Inflammation, Mice, Transgenic, Biology, Biochemistry, Monocytes, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, In vivo, medicine, Extracellular, Macrophage, Animals, Humans, Scavenger receptor, Receptor, Blood Coagulation, Cells, Cultured, Factor X, Macrophages, Scavenger Receptors, Class A, Cell Differentiation, Cell Biology, Hematology, Molecular biology, In vitro, Mice, Inbred C57BL, 030104 developmental biology, HEK293 Cells, chemistry, medicine.symptom, 030215 immunology
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المؤلفون: Amine Bazaa, Libia Sanz, Alicia Pérez, Mehdi Chenik, Naziha Marrakchi, Juan J. Calvete, Zakaria Bel Lasfer, Mohamed El Ayeb
المساهمون: Instituto de biomedicina [Valencia] (IBV), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Laboratoire des Venins et Biomolécules Thérapeutiques - Laboratory of Venoms and Therapeutic Biomolecules (LR11IPT08), Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Laboratoire de Transmission, Contrôle et Immunobiologie des Infections - Laboratory of Transmission, Control and Immunobiology of Infection (LR11IPT02)
المصدر: Biochemical Journal
Biochemical Journal, Portland Press, 2006, 395 (2), pp.385-392. ⟨10.1042/BJ20051678⟩
Digital.CSIC. Repositorio Institucional del CSIC
instnameمصطلحات موضوعية: Integrins, integrin inhibition, Cerastes vipera, Macrovipera lebetina transmediterranea, Integrin Inhibition, Disintegrins, [SDV]Life Sciences [q-bio], Biochemistry, Viperidae, Cloning, Molecular, Genetics, snake venom disintegrin, 0303 health sciences, biology, toxin evolution, 030302 biochemistry & molecular biology, 3. Good health, Toxin evolution, Snake venom, embryonic structures, snake venomics, Macrovipera lebetina, Dimerization, Oligopeptides, Research Article, endocrine system, DNA, Complementary, Sequence analysis, Molecular Sequence Data, Viper Venoms, Molecular cloning, Evolution, Molecular, 03 medical and health sciences, Disintegrin, Animals, Amino Acid Sequence, Snake venomics, Snake venom disintegrin, Molecular Biology, Gene Library, 030304 developmental biology, Base Sequence, cDNA library, Spectrum Analysis, Cell Biology, biology.organism_classification, Molecular biology, carbohydrates (lipids), Integrin inhibition, biology.protein, Sequence Alignment
وصف الملف: 763802 bytes; application/pdf
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المؤلفون: Benoit Decouture, Cécile V. Denis, Blandine Dizier, Orjeta Kuci, Bérard Coqueran, Elise Dreano, Pascale Gaussem, Jean-Sébastien Hulot, Anne-Marie Lompré, Amine Bazaa, Christilla Bachelot-Loza, Tiphaine Belleville-Rolland
المصدر: Blood. 126(15)
مصطلحات موضوعية: Blood Platelets, medicine.medical_specialty, Platelet Aggregation, Platelet Function Tests, Immunology, Integrin, ABCC4, Biochemistry, Mice, Internal medicine, medicine, Cyclic AMP, Animals, Homeostasis, Platelet, Platelet activation, Phosphorylation, Cells, Cultured, Mice, Knockout, biology, Kinase, Biological Transport, Thrombosis, Cell Biology, Hematology, Platelet Activation, Platelets and Thrombopoiesis, Adenosine, Cyclic AMP-Dependent Protein Kinases, Endocrinology, biology.protein, Signal transduction, Multidrug Resistance-Associated Proteins, Platelet factor 4, medicine.drug, Signal Transduction
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المؤلفون: Imen Aissa, Youssef Gargouri, Raoudha Zouari-Kesentini, Najet Srairi-Abid, Jed Jebali, Houcemeddine Othman, Zaineb Abdelkafi-Koubaa, Amen Allah Ellefi, Naziha Marrakchi, Hafedh Majdoub, Mohamed El Ayeb, Maram Morjen, Amine Bazaa
المساهمون: Laboratoire des Venins et Biomolécules Thérapeutiques - Laboratory of Venoms and Therapeutic Biomolecules (LR11IPT08), Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Laboratoire de Biochimie et de Génie Enzymatique des Lipases, École Nationale d'Ingénieurs de Sfax | National School of Engineers of Sfax (ENIS), USCR Séquenceur de Protéines, Faculté des Sciences de Sfax, Université de Sfax - University of Sfax-Université de Sfax - University of Sfax, Faculté de Médecine de Tunis, Université de Tunis El Manar (UTM), This work received financial support from the Ministry of Higher Education, Scientific Research in Tunisia.
المصدر: Toxicon
Toxicon, Elsevier, 2014, 89, pp.32-44. ⟨10.1016/j.toxicon.2014.06.020⟩مصطلحات موضوعية: Snake venom, Glycosylation, [SDV]Life Sciences [q-bio], Molecular Sequence Data, Viper Venoms, Toxicology, L-amino-acid oxidase, L-Amino Acid Oxidase, Chromatography, Affinity, Substrate Specificity, L -amino acid oxidase, 03 medical and health sciences, Affinity chromatography, Sequence Analysis, Protein, Amino Acid Sequence, Cloning, Molecular, Peptide sequence, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Chromatography, Edman degradation, biology, Base Sequence, 030302 biochemistry & molecular biology, Tryptophan, cDNA sequence, Cerastes cerastes, biology.organism_classification, Chromatography, Ion Exchange, Amino acid, Kinetics, Biochemistry, chemistry, [SDV.TOX]Life Sciences [q-bio]/Toxicology, Chromatography, Gel, Electrophoresis, Polyacrylamide Gel, Sequence Alignment, Tertiary model
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المؤلفون: Maram Morjen, Zaineb Abdelkafi-Koubaa, José Luis, Mohamed El Ayeb, Ameneallah Ellafi, Hervé Kovacic, Stéphane Honoré, Amine Bazaa, Naziha Marrakchi, Kamel Mabrouk
المساهمون: Laboratoire des Venins et Biomolécules Thérapeutiques - Laboratory of Venoms and Therapeutic Biomolecules (LR11IPT08), Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Centre de Recherches en Oncologie biologique et Oncopharmacologie (CRO2), Institut National de la Santé et de la Recherche Médicale (INSERM)- Hôpital de la Timone [CHU - APHM] (TIMONE)-Aix Marseille Université (AMU), Service Pharmacie [Hôpital de la Timone - APHM], Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), Institut de Chimie Radicalaire (ICR), Aix Marseille Université (AMU)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Faculté de Médecine de Tunis, Université de Tunis El Manar (UTM), This work was supported in part by MERST (Ministère de l’'Enseignement Supérieur de la Recherche et de la Technologie) (Laboratoire des venins et biomolécules thérapeutiques: LR11IPT08), INSERM UMR911 (Institut National de la Santé et de la Recherche Médicale) and by grants ARCUS (Action en Région de Coopération Universitaire et Scientifique (2008-2012) partners: Centre de recherche en oncologie biologique et onco-pharmacologie (CRO2), INSERM UMR911, Marseille, LVT (Institut Pasteur de Tunis), Laboratoire de génétique moléculaire des eucaryotes université de sfax tunisie) andINCa (Institut National du Cancer), Aix Marseille Université (AMU)- Hôpital de la Timone [CHU - APHM] (TIMONE)-Institut National de la Santé et de la Recherche Médicale (INSERM)
المصدر: Microvascular Research
Microvascular Research, Elsevier, 2014, 95, pp.149-56. ⟨10.1016/j.mvr.2014.08.006⟩
Microvascular Research, 2014, 95, pp.149-56. ⟨10.1016/j.mvr.2014.08.006⟩مصطلحات موضوعية: Serine Proteinase Inhibitors, Time Factors, Angiogenesis, [SDV]Life Sciences [q-bio], Amino Acid Motifs, Integrin, Neovascularization, Physiologic, Angiogenesis Inhibitors, Chick Embryo, Viper Venoms, Microtubule dynamics, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Transfection, Microtubules, Biochemistry, Chorioallantoic Membrane, Chorioallantoic membrane assay, Cell Line, Cell Movement, In vivo, Cell Adhesion, Animals, Humans, Cytotoxicity, Migration, Serine protease, Dose-Response Relationship, Drug, biology, Endothelial Cells, Cell Biology, Integrin alphaVbeta3, Molecular biology, In vitro, 3. Good health, Cell biology, Endothelial stem cell, Fibronectin, biology.protein, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, Cardiology and Cardiovascular Medicine, Integrin alpha5beta1
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المؤلفون: Jed Jebali, José Luis, Assou el Battari, Amine Bazaa, Maram Morjen, Naziha Marrakchi, Sylvie Mathieu, Charlotte Jeanneau, Ali Gargouri, Mohamed El Ayeb
المساهمون: Laboratoire des Venins et Toxines, Institut Pasteur de Tunis, Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Laboratoire de Valorisation de la Biomasse et Production de Protéines chez les Eucaryotes [Sfax, Tunisie], Centre de Biotechnologie de Sfax (CBS), Centre de Recherches en Oncologie biologique et Oncopharmacologie (CRO2), Aix Marseille Université (AMU)- Hôpital de la Timone [CHU - APHM] (TIMONE)-Institut National de la Santé et de la Recherche Médicale (INSERM), Réseau International des Instituts Pasteur (RIIP), Faculté de Médecine de Tunis, Université de Tunis El Manar (UTM), The authors like to express their gratitude to Mr Anouar Smaoui from the English Language Unit at the Faculty of Science of Sfax, Tunisia, for his valuable help with the proofreading and language polishing of the present article.
المصدر: Biotechnology Progress
Biotechnology Progress, Wiley, 2012, 28 (6), pp.1560-1565. ⟨10.1002/btpr.1632⟩مصطلحات موضوعية: Integrins, C‐type lectin, MESH: Viper Venoms/biosynthesis, MESH: Cricetinae, Kidney, MESH: Lectins, C-Type/chemistry, MESH: Kidney/cytology, law.invention, MESH: Cell Movement/drug effects, MESH: Cell Proliferation/drug effects, MESH: Cricetulus, Cell Movement, C-type lectin, law, Cricetinae, lebecetin, MESH: Recombinant Proteins/biosynthesis, MESH: Animals, snake venom, MESH: Viper Venoms/genetics, 0303 health sciences, biology, 030302 biochemistry & molecular biology, Transfection, MESH: Protein Subunits, MESH: Kidney/metabolism, MESH: Viper Venoms/chemistry, Recombinant Proteins, MESH: Integrins/metabolism, MESH: Recombinant Proteins/chemistry, MESH: HEK293 Cells, Recombinant DNA, Biotechnology, MESH: Cell Line, Tumor, integrin, Protein subunit, Blotting, Western, CHO Cells, Viper Venoms, 03 medical and health sciences, Cricetulus, Affinity chromatography, MESH: CHO Cells, MESH: Viper Venoms/pharmacology, Cell Line, Tumor, Complementary DNA, Animals, Humans, MESH: Blotting, Western, Lectins, C-Type, MESH: Recombinant Proteins/genetics, MESH: Recombinant Proteins/pharmacology, Cell Proliferation, 030304 developmental biology, MESH: Humans, heterodimerization, MESH: Lectins, C-Type/genetics, Lectin, Embryo, Mammalian, Molecular biology, Protein Subunits, HEK293 Cells, Glycoprotein Ib, biology.protein, MESH: Lectins, C-Type/biosynthesis, MESH: Embryo, Mammalian/cytology, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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المؤلفون: Olfa Kallech-Ziri, Mohamed El Ayeb, Amine Bazaa, Houcemeddine Othman, Libia Sanz, Raoudha Zouari-Kessentini, Naziha Marrakchi, Najet Srairi-Abid, José Luis, Kamel Mabrouk, Maram Morjen, Juan J. Calvete
المساهمون: Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP), Laboratoire des Venins et Biomolécules Thérapeutiques - Laboratory of Venoms and Therapeutic Biomolecules (LR11IPT08), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Institut de Chimie Radicalaire (ICR), Aix Marseille Université (AMU)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Instituto de biomedicina [Valencia] (IBV), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Centre de Recherches en Oncologie biologique et Oncopharmacologie (CRO2), Aix Marseille Université (AMU)- Hôpital de la Timone [CHU - APHM] (TIMONE)-Institut National de la Santé et de la Recherche Médicale (INSERM), Aix Marseille Université (AMU), Faculté de Médecine de Tunis, Faculte de Medecine de Tunis, This work was supported in part by MERST (Ministère de l'Enseignement Supérieur de la Recherche et de la Technologie) by INSERM and by grants from the ARCUS (Action en Region de Cooperation Universitaire et Scientifique)., Institut National de la Santé et de la Recherche Médicale (INSERM)- Hôpital de la Timone [CHU - APHM] (TIMONE)-Aix Marseille Université (AMU)
المصدر: Matrix Biology
Matrix Biology, 2013, 32 (1), pp.52-62. ⟨10.1016/j.matbio.2012.11.015⟩
Matrix Biology, Elsevier, 2013, 32 (1), pp.52-62. ⟨10.1016/j.matbio.2012.11.015⟩مصطلحات موضوعية: Models, Molecular, MESH: Sequence Analysis, DNA, Protein Conformation, Amino Acid Motifs, MESH: Viperidae, Venom, MESH: Amino Acid Sequence, MESH: Base Sequence, MESH: Dose-Response Relationship, Drug, Serine, MESH: Amino Acid Motifs, MESH: Protein Conformation, 0302 clinical medicine, Cell Movement, Tandem Mass Spectrometry, Viperidae, Cytotoxic T cell, MESH: Animals, Cloning, Molecular, MESH: Cell Movement, Chromatography, High Pressure Liquid, 0303 health sciences, Microscopy, Video, biology, MESH: Peptides, 3. Good health, MESH: Integrin alphaVbeta3, Snake venom, 030220 oncology & carcinogenesis, MESH: Viper Venoms, MESH: Tunisia, Macrovipera lebetina, MESH: Models, Molecular, MESH: DNA Primers, MESH: Cell Line, Tumor, DNA, Complementary, Serine Proteinase Inhibitors, Tunisia, MESH: Serine Proteinase Inhibitors, Integrin, Molecular Sequence Data, MESH: Sequence Alignment, Motility, Viper Venoms, Time-Lapse Imaging, MESH: Cell Adhesion, Lethal Dose 50, 03 medical and health sciences, Cell Line, Tumor, Cell Adhesion, Animals, Humans, MESH: Cloning, Molecular, Amino Acid Sequence, MESH: Time-Lapse Imaging, MESH: Chromatography, High Pressure Liquid, Molecular Biology, 030304 developmental biology, DNA Primers, Serine protease, MESH: Humans, MESH: Molecular Sequence Data, Base Sequence, Dose-Response Relationship, Drug, MESH: Tandem Mass Spectrometry, MESH: DNA, Complementary, Sequence Analysis, DNA, biology.organism_classification, Integrin alphaVbeta3, Molecular biology, MESH: Microscopy, Video, MESH: Lethal Dose 50, biology.protein, Peptides, Sequence Alignment
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المؤلفون: Ines Limam, Olfa Kallech-Ziri, Salma Taboubi, Asma Hammami, José Luis, Jed Jebali, Amine Bazaa, Hafedh Mejdoub, Mohamed El Ayeb, Raoudha Zouari-Kessentini, Najet Srairi-Abid, Naziha Marrakchi
المساهمون: Laboratoire des Venins et Toxines, Institut Pasteur de Tunis, Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Centre de Recherches en Oncologie biologique et Oncopharmacologie (CRO2), Aix Marseille Université (AMU)- Hôpital de la Timone [CHU - APHM] (TIMONE)-Institut National de la Santé et de la Recherche Médicale (INSERM), USCR séquenceur de protéines, Faculté des Sciences de Sfax, Université de Sfax - University of Sfax-Université de Sfax - University of Sfax, Faculté de Médecine, Faculte de Medecine de Tunis, Institut National de la Santé et de la Recherche Médicale (INSERM)- Hôpital de la Timone [CHU - APHM] (TIMONE)-Aix Marseille Université (AMU)
المصدر: Matrix Biology
Matrix Biology, Elsevier, 2010, 29 (2), pp.117-26. ⟨10.1016/j.matbio.2009.09.009⟩مصطلحات موضوعية: Models, Molecular, Integrins, Platelet Aggregation, Disintegrins, MESH: Viperidae, MESH: Antigens, Neoplasm, MESH: Amino Acid Sequence, MESH: Base Sequence, Conserved sequence, MESH: Protein Structure, Tertiary, Protein structure, Viperidae, MESH: Animals, Peptide sequence, MESH: Platelet Aggregation, 0303 health sciences, biology, 030302 biochemistry & molecular biology, MESH: Integrins, MESH: Integrin alphaVbeta3, Biochemistry, MESH: Platelet Aggregation Inhibitors, Jararhagin, Integrin alpha2beta1, MESH: Viper Venoms, Macrovipera lebetina, MESH: Models, Molecular, Integrin alpha5beta1, MESH: Cell Line, Tumor, Molecular Sequence Data, Integrin, MESH: Sequence Alignment, Viper Venoms, MESH: Cell Adhesion, 03 medical and health sciences, Antigens, Neoplasm, Cell Line, Tumor, Cell Adhesion, Disintegrin, Animals, Humans, Amino Acid Sequence, Cysteine, MESH: Disintegrins, Cell adhesion, Molecular Biology, 030304 developmental biology, MESH: Molecular Sequence Data, MESH: Humans, Base Sequence, MESH: Integrin alpha5beta1, MESH: Cysteine, Integrin alphaVbeta3, biology.organism_classification, Molecular biology, Protein Structure, Tertiary, biology.protein, Sequence Alignment, Platelet Aggregation Inhibitors, MESH: Integrin alpha2beta1
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المؤلفون: Eddy Pasquier, José Luis, Amine Bazaa, Raoudha Kessentini-Zouari, Assou el Battari, Naziha Marrakchi, Ines Limam, Céline Defilles, Diane Braguer, Olfa Kallech-Ziri, Mohamed El Ayeb
المساهمون: Laboratoire des Venins et Toxines, Institut Pasteur de Tunis, Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Centre de Recherches en Oncologie biologique et Oncopharmacologie (CRO2), Institut National de la Santé et de la Recherche Médicale (INSERM)- Hôpital de la Timone [CHU - APHM] (TIMONE)-Aix Marseille Université (AMU), Faculté de médecine de Tunis, Faculte de Medecine de Tunis, Aix Marseille Université (AMU)- Hôpital de la Timone [CHU - APHM] (TIMONE)-Institut National de la Santé et de la Recherche Médicale (INSERM), Ben Hassine, Hichem
المصدر: PLoS ONE
PLoS ONE, Public Library of Science, 2010, 5 (4), pp.e10124. ⟨10.1371/journal.pone.0010124⟩
PLoS ONE, Vol 5, Iss 4, p e10124 (2010)مصطلحات موضوعية: Integrins, Role of cell adhesions in neural development, Angiogenesis, Endothelial cells, lcsh:Medicine, Angiogenesis Inhibitors, Microtubules, MESH: Dose-Response Relationship, Drug, 0302 clinical medicine, Cell Movement, MESH: Animals, MESH: Endothelial Cells, lcsh:Science, MESH: Cell Movement, MESH: Phospholipases A2, Cells, Cultured, Cytoskeleton, MESH: Angiogenesis Inhibitors, 0303 health sciences, Multidisciplinary, biology, MESH: Microtubules, Cell migration, Snakes, Cell Biology/Extra-Cellular Matrix, 3. Good health, Cell biology, [SDV.TOX] Life Sciences [q-bio]/Toxicology, 030220 oncology & carcinogenesis, [SDV.TOX]Life Sciences [q-bio]/Toxicology, MESH: Endothelium, Vascular, MESH: Neovascularization, Physiologic, Snake Venoms, Research Article, MESH: Cells, Cultured, Integrin, Neovascularization, Physiologic, MESH: Cell Adhesion, Focal adhesion, 03 medical and health sciences, Cell Biology/Cytoskeleton, Cell Adhesion, Animals, Humans, Cell adhesion, 030304 developmental biology, Matrigel, Focal Adhesions, MESH: Snake Venoms, MESH: Humans, Dose-Response Relationship, Drug, Venoms, lcsh:R, MESH: Focal Adhesions, Actin cytoskeleton, Actins, Phospholipases A2, Cell Biology/Cell Adhesion, biology.protein, lcsh:Q, Endothelium, Vascular
وصف الملف: application/pdf
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المؤلفون: Raoudha Kessentini-Zouari, José Luis, Jean-Claude Lissitzky, Amine Bazaa, Mohamed El Ayeb, Céline Defilles, Olfa Kallech-Ziri, Najet Srairi-Abid, Naziha Marrakchi
المساهمون: Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP), Centre de Recherches en Oncologie biologique et Oncopharmacologie (CRO2), Aix Marseille Université (AMU)- Hôpital de la Timone [CHU - APHM] (TIMONE)-Institut National de la Santé et de la Recherche Médicale (INSERM), Faculté de Médecine de Tunis, Université de Tunis El Manar (UTM)
المصدر: Matrix Biology
Matrix Biology, Elsevier, 2009, 28 (4), pp.188-93. ⟨10.1016/j.matbio.2009.03.007⟩مصطلحات موضوعية: MESH: Neoplasm Proteins, Integrins, MESH: Sequence Homology, Amino Acid, Fibrosarcoma, MESH: Viperidae, MESH: Antigens, Neoplasm, MESH: Catalytic Domain, Venom, MESH: Amino Acid Sequence, MESH: Structure-Activity Relationship, Cell Movement, Catalytic Domain, Viperidae, MESH: Animals, Cytotoxicity, Melanoma, MESH: Phospholipases A2, MESH: Cell Movement, 0303 health sciences, biology, MESH: Fibrosarcoma, 030302 biochemistry & molecular biology, MESH: Drug Screening Assays, Antitumor, MESH: Integrins, Neoplasm Proteins, 3. Good health, MESH: Integrin alphaVbeta3, Biochemistry, Snake venom, lipids (amino acids, peptides, and proteins), MESH: Viper Venoms, Macrovipera lebetina, Integrin alpha5beta1, MESH: Cell Line, Tumor, MESH: Melanoma, Molecular Sequence Data, Integrin, MESH: Sequence Alignment, Antineoplastic Agents, Viper Venoms, MESH: Cell Adhesion, Structure-Activity Relationship, 03 medical and health sciences, Phospholipase A2, Antigens, Neoplasm, Cell Line, Tumor, Cell Adhesion, Animals, Humans, Amino Acid Sequence, Cell adhesion, Molecular Biology, 030304 developmental biology, MESH: Humans, MESH: Molecular Sequence Data, Sequence Homology, Amino Acid, MESH: Integrin alpha5beta1, cDNA library, Integrin alphaVbeta3, biology.organism_classification, Molecular biology, Phospholipases A2, biology.protein, MESH: Antineoplastic Agents, Drug Screening Assays, Antitumor, Sequence Alignment
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المؤلفون: Robert A. Harrison, Amine Bazaa, N. Marrakchi, Juan J. Calvete, Paula Juárez, Mohamed El Ayeb, Libia Sanz, Zakaria Bel Lasfer
المساهمون: Laboratoire des Venins et Toxines, Institut Pasteur de Tunis, Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Instituto de biomedicina [Valencia] (IBV), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Alistair Reid Venom Research Unit, Liverpool School of Tropical Medicine (LSTM), This study was partly financed by Grant BFU2004-01432/BMC from the Ministerio de Educacion y Ciencia, Madrid, Spain, and by Spanish-Tunisian Cooperation Programme 29p/02 of the Agencia Espanola de Cooperacion Internacional (AECI). P.J. is the recipient of a predoctoral fel-lowship from the Formacion de Personal Investigador (FPI) program from the Ministerio de Educacion y Ciencia, Madrid.
المصدر: Journal of Molecular Evolution
Journal of Molecular Evolution, Springer Verlag, 2007, 64 (2), pp.261-271. ⟨10.1007/s00239-006-0161-4⟩مصطلحات موضوعية: Macrovipera lebetina transmediterranea, genomic DNA, MESH: Sequence Homology, Amino Acid, MESH: Introns, Disintegrins, [SDV]Life Sciences [q-bio], MESH: Viperidae, MESH: Amino Acid Sequence, MESH: Base Sequence, Viperidae, MESH: Animals, MESH: Genetic Variation, MESH: Phylogeny, Phylogeny, Sequence Deletion, Genetics, 0303 health sciences, biology, 030302 biochemistry & molecular biology, MESH: DNA, MESH: Sequence Deletion, Snake venom, RNA splicing, embryonic structures, MESH: Viper Venoms, Macrovipera lebetina, MESH: DNA Primers, endocrine system, DNA, Complementary, Sequence analysis, Molecular Sequence Data, MESH: Sequence Alignment, Viper Venoms, 03 medical and health sciences, intronless gene, Disintegrin, Animals, Amino Acid Sequence, intron sequence, MESH: Disintegrins, Molecular Biology, Gene, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, DNA Primers, MESH: Molecular Sequence Data, Base Sequence, Sequence Homology, Amino Acid, urogenital system, disintegrin evolution, Intron, Genetic Variation, DNA, MESH: DNA, Complementary, biology.organism_classification, Introns, carbohydrates (lipids), Echis ocellatus, biology.protein, Sequence Alignment
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المؤلفون: Libia Sanz, Mohamed El Ayeb, Naziha Marrakchi, Juan J. Calvete, Amine Bazaa
المساهمون: Laboratoire des Venins et Toxines, Institut Pasteur de Tunis, Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), This study has been partly financed by grant BFU2004–01432/BMC from the Ministerio de Educación y Ciencia, Madrid, Spain, and by the Spanish-Tunisian Cooperation Programme 29p/02 from the Agencia Española de Cooperación Internacional (AECI)., The authors wish to thank Dr. Ben Lasfar Z. from Pasteur Institute of Tunis for providing the venoms.
المصدر: Proteomics
Proteomics, Wiley-VCH Verlag, 2005, 5 (16), pp.4223-4235. ⟨10.1002/pmic.200402024⟩مصطلحات موضوعية: Cerastes vipera, Proteome, Disintegrins, Venom, MESH: Amino Acid Sequence, Proteomics, Biochemistry, Macrovipera lebetina, Viperidae, MESH: Animals, 0303 health sciences, 030302 biochemistry & molecular biology, Serine Endopeptidases, [SDV.TOX]Life Sciences [q-bio]/Toxicology, MESH: Metalloproteases/metabolism, MESH: Viperidae/metabolism, MESH: Viper Venoms/metabolism, MESH: Lectins, C-Type/metabolism, Protein family, Sequence analysis, Molecular Sequence Data, Zoology, Viper Venoms, Biology, complex mixtures, Phospholipases A, Capillary Permeability, 03 medical and health sciences, MESH: Serine Endopeptidases/metabolism, Cerastes cerastes, Animals, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Lectins, C-Type, Amino Acid Sequence, Snake venomics, Molecular Biology, 030304 developmental biology, N‐terminal sequencing, MESH: Molecular Sequence Data, MESH: Capillary Permeability, biology.organism_classification, MESH: Phospholipases A/metabolism, MESH: Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, MESH: Disintegrins/metabolism, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Metalloproteases, MESH: Proteome/analysis
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المؤلفون: Youssef Gargouri, Jed Jebali, Amine Bazaa, Zaineb Abdelkafi-Koubaa, N. Marrakchi, Hafedh Majdoub, Imen Aissa, Najet Srairi-Abid, Maram Morjen, M. El Ayeb, Houcemeddine Othman, R. Zouari-Kesentini
المصدر: Toxicon. 91:174
مصطلحات موضوعية: Biochemistry, biology, Snake venom, Chemistry, Cerastes cerastes, Toxicology, L-amino-acid oxidase, biology.organism_classification